Page last updated: 2024-08-05 11:00:53
anthracycline
Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.
ChEBI ID: 48120
Members (16)
| Member | Definition | Role |
|---|
| (7R,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | | (7R,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
| (7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | | (7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
| aclacinomycin | An anthracycline that is aklavinone having an alpha-L-rhodosaminyl residue attached at position 4 via a glycosidic linkage. | aclacinomycin T zwitterion; aclacinomycin T |
| aclarubicin | An anthracycline antibiotic that is produced by Streptomyces galilaeus and also has potent antineoplastic activity. | aclacinomycin A zwitterion; aclacinomycin A |
| aklavinone | | aklavinone |
| daunorubicin | A natural product found in Actinomadura roseola. | daunorubicin |
| daunorubicin hydrochloride | | Daunorubicin hydrochloride |
| doxorubicin hydrochloride | | Doxorubicin hydrochloride |
| epirubicin | An anthracycline that is the 4'-epi-isomer of doxorubicin. | 4'-epidoxorubicin |
| idarubicin hydrochloride | | Idarubicin hydrochloride |
| idarubicinol | | Idarubicinol |
| nsc-267703 | | 7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
| pirarubicin | | (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
| pirarubicin hydrochloride | | Pirarubicin |
| pyrromycin | | Pyrromycin |
| valrubicin | | valrubicin |
Research
Studies (14,324)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 3,877 (27.07) | 18.7374 |
| 1990's | 3,496 (24.41) | 18.2507 |
| 2000's | 3,206 (22.38) | 29.6817 |
| 2010's | 3,058 (21.35) | 24.3611 |
| 2020's | 687 (4.80) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 2,978 (18.60%) | 5.53% |
| Reviews | 792 (4.95%) | 6.00% |
| Case Studies | 1,410 (8.81%) | 4.05% |
| Observational | 39 (0.24%) | 0.25% |
| Other | 10,789 (67.40%) | 84.16% |