Page last updated: 2024-08-05 11:15:52

stilbenoid

Any olefinic compound characterised by a 1,2-diphenylethylene backbone.

ChEBI ID: 26776

Members (85)

MemberDefinitionRole
(+)-trans-epsilon-viniferinA stilbenoid that is the (+)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol.(+)-trans-epsilon-viniferin
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucosideA stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside.(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside
1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
1-(3,4-dimethoxy-2-methylphenyl)-2-(3,4-dimethoxyphenyl)ethanone1-(3,4-dimethoxy-2-methylphenyl)-2-(3,4-dimethoxyphenyl)ethanone
1-(4-bromophenyl)-2-phenylethan-1-one1-(4-bromophenyl)-2-phenylethan-1-one
1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol
1-(4-hydroxyphenyl)-2-phenylethan-1-one1-(4-hydroxyphenyl)-2-phenylethan-1-one
2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone
2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone
2-[(4,7-dimethyl-2-quinazolinyl)thio]-1,2-diphenylethanone2-[(4,7-dimethyl-2-quinazolinyl)thio]-1,2-diphenylethanone
2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
2-chloro-N-(1,2-diphenylethyl)acetamide2-chloro-N-(1,2-diphenylethyl)acetamide
2,3,3-triphenylacrylonitrile2,3,3-Triphenylacrylonitrile
3-[[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(2-methoxyphenyl)-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone3-[[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(2-methoxyphenyl)-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone
3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid
3,3'-Dihydroxyhexestrol3,3'-Dihydroxyhexestrol
3,3',4,5'-tetrahydroxystilbene4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
3,5-dimethoxy-trans-stilbene(E)-3,5-Dimethoxystilbene
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid4-Acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid
4-hydroxy-n-desmethyltamoxifen4-Hydroxy-N-desmethyltamoxifen
4,5-diphenyl-1,5-dihydroimidazol-2-one4,5-diphenyl-1,5-dihydroimidazol-2-one
5-[2-(4-ethoxy-2-hydroxyphenyl)-2-oxoethyl]-2-benzofurancarboxylic acid5-[2-(4-ethoxy-2-hydroxyphenyl)-2-oxoethyl]-2-benzofurancarboxylic acid
aiphanolA lignan that is (2R)-2,3-dihydro-1,4-benzodioxin-2-ylmethanol which is substituted by a 2-(3,5-dihydroxyphenyl)ethenyl group at position 6 and a 4-hydroxy-3,5-dimethoxyphenyl group at position 3. It is a stilbenolignan isolated from the seeds of Aiphanes aculeata and exhibits potent inhibitory efficacy against cyclooxygenase-1 and -2 (COX-1 and COX-2).aiphanol
alpha-hydroxytamoxifenalpha-Hydroxytamoxifen
amorfrutin aAmorfrutin A
astringinA stilbenoid that is piceatannol substituted at position 3 by a beta-D-glucosyl residue.trans-astringin
batatasin-iiiBatatasin III
bay94 9172A member of the class of stilbenoids in which the para-hydrogens of stilbene are replaced by methylamino and 2-{2-[2-((18)F)fluoroethoxy]ethoxy}ethoxy) groups. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease.florbetaben ((18)F)
bms 204493A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenylethynyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer).BMS-493
bms453A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma.BMS-453
cajanine2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid
delta-viniferinA stilbenoid that is the (2S,3S)-trans-stereoisomer of delta-viniferin, obtained by cyclodimerisation of trans-resveratrol.(2S,3S)-trans-delta-viniferin
desdimethyltamoxifenN,N-Didesmethyltamoxifen
desoxyrhaponticinDesoxyrhaponticin
diethylstilbestrol4-[4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
dimethylstilbestrolDimethylstilbestrol
diphenidine1-(1,2-diphenylethyl)piperidine
droloxifeneDroloxifene
epsilon-viniferinA stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol.(-)-trans-epsilon-viniferin
ethamoxytriphetolEthamoxytriphetol
fosbretabulinCombretastatin A4
gw 4064GW 4064
hexestrolhexestrol
hexestrol bis(diethylaminoethyl ether)diethylaminoethoxyhexestrol
idoxifeneIdoxifene
iodoalphionic acidpheniodol sodium
isorhapontigeninIsorhapontigenin
isorhapontinIsorhapontin
lephetaminelefetamine
lunularic acidLunularic acid
lunularinLunularin
ly 288513(4S,5R)-N-(4-bromophenyl)-3-oxo-4,5-diphenyl-1-pyrazolidinecarboxamide
metaflumizoneMetaflumizone
mulberroside acis-Mulberroside A
n-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamideTaranabant
n-desmethyltamoxifenN-Desmethyltamoxifen
n-desmethyltoremifeneN-desmethyltoremifene
norpropoxypheneNorpropoxyphene
nutlin 34-[[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazol-1-yl]-oxomethyl]-2-piperazinone
nutlin-3a4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazol-1-yl]-oxomethyl]-2-piperazinone
o-desmethylangolensinO-Desmethylangolensin
pallidolA tetracyclic stilbenoid that is a homodimer obtained by cyclodimerisation of resveratrol.pallidol
palovarotenePalovarotene
Pinosylvin methyl etherPinosylvin methyl ether
polydatinA stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue.trans-piceid
quadrangularin aAn indane-derived stilbenoid that is a homodimer obtained by cyclodimerisation of resveratrol.quadrangularin A
remacemide2-amino-N-(1,2-diphenylpropan-2-yl)acetamide
resveratrol-4'-o-glucuronidetrans-Resveratrol 4'-O-glucuronide
rhapontigeninRhapontigenin
salvianolic acid aSalvianolic acid A
sarpogrelatesarpogrelate
sc 57666SC-57666
schweinfurthin fA stilbenoid isolated from Macaranga alnifolia and has been shown to exhibit cytotoxic activity.schweinfurthin F
schweinfurthin gA stilbenoid that is the 3-deoxy derivative of vedelianin. Isolated from Macaranga alnifolia, it exhibits cytotoxic activity.schweinfurthin G
tamoxifentamoxifen
tetraphenylcyclopentadienoneTetraphenylcyclopentadienone
toremifene citrateToremifene citrate
trans-2,3',4,5'-tetrahydroxystilbeneOxyresveratrol
triparanoltriparanol
triphenylethyleneTriphenylethylene
vedelianinA stilbenoid derivative isolated from Macaranga alnifolia and Macaranga alnifolia and has been shown to exhibit cytotoxic activity.vedelianin
zuclomiphenezuclomifene

Research

Studies (24,888)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19904,166 (16.74)18.7374
1990's5,107 (20.52)18.2507
2000's6,658 (26.75)29.6817
2010's7,178 (28.84)24.3611
2020's1,779 (7.15)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials2,419 (8.90%)5.53%
Reviews3,006 (11.05%)6.00%
Case Studies1,287 (4.73%)4.05%
Observational68 (0.25%)0.25%
Other20,415 (75.07%)84.16%