Any pyridone which is substituted on the nitrogen by a hydroxy group and which has been used as an antifungal drug.
ChEBI ID: 87130
| Member | Definition | Role |
|---|---|---|
| ciclopirox | A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, respectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections. | ciclopirox |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 46 (10.75) | 18.7374 |
| 1990's | 43 (10.05) | 18.2507 |
| 2000's | 134 (31.31) | 29.6817 |
| 2010's | 150 (35.05) | 24.3611 |
| 2020's | 55 (12.85) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 76 (16.14%) | 5.53% |
| Reviews | 50 (10.62%) | 6.00% |
| Case Studies | 47 (9.98%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 298 (63.27%) | 84.16% |