Page last updated: 2024-08-05 10:58:45

pyridazines

null

ChEBI ID: 37921

Members (44)

MemberDefinitionRole
1-(3,4-dimethylphenyl)-4-(4-methyl-1-piperidinyl)phthalazine1-(3,4-dimethylphenyl)-4-(4-methyl-1-piperidinyl)phthalazine
1,3,8-trimethyl-5,10-diphenylpyrimido[1,2]pyrrolo[4,5-b]pyridazine-2,4-dione1,3,8-trimethyl-5,10-diphenylpyrimido[1,2]pyrrolo[4,5-b]pyridazine-2,4-dione
2-(4-nitrophenoxy)-1-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethanone2-(4-nitrophenoxy)-1-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethanone
2-[(2,6-dichlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone2-[(2,6-dichlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
2-[(3-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone2-[(3-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
2-[(4-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone2-[(4-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(1-pyrrolidinyl)ethanone2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(1-pyrrolidinyl)ethanone
2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(4-morpholinyl)ethanone2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(4-morpholinyl)ethanone
2-[[6-(4-ethylphenyl)-3-pyridazinyl]thio]-N-(2-oxolanylmethyl)acetamide2-[[6-(4-ethylphenyl)-3-pyridazinyl]thio]-N-(2-oxolanylmethyl)acetamide
2-[2-oxo-2-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethyl]isoindole-1,3-dione2-[2-oxo-2-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethyl]isoindole-1,3-dione
2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide
3-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]-N-[2-(2-methyl-1-piperidinyl)ethyl]propanamide3-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]-N-[2-(2-methyl-1-piperidinyl)ethyl]propanamide
3-amino-5-(4-bromophenyl)-4-pyridazinecarbonitrile3-amino-5-(4-bromophenyl)-4-pyridazinecarbonitrile
3-chloro-6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine3-chloro-6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine
3-oxido-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium3-oxido-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium
3-phenyl-1H-cinnolin-4-one3-phenyl-1H-cinnolin-4-one
4-(2,4-dimethylphenyl)-2H-phthalazin-1-one4-(2,4-dimethylphenyl)-2H-phthalazin-1-one
4-(3-bromophenyl)-2-(4-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine4-(3-bromophenyl)-2-(4-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine
4-(3-bromophenyl)-7-methyl-2-(4-methylphenyl)pyrazolo[3,4-d]pyridazine4-(3-bromophenyl)-7-methyl-2-(4-methylphenyl)pyrazolo[3,4-d]pyridazine
4-(4-hydroxy-3,5-dimethylphenyl)-2-methylphthalazin-1(2H)-one4-(4-hydroxy-3,5-dimethylphenyl)-2-methylphthalazin-1(2H)-one
4-[6-amino-3-(4-methoxyphenyl)-1-pyridazin-1-iumyl]butanoic acid4-[6-amino-3-(4-methoxyphenyl)-1-pyridazin-1-iumyl]butanoic acid
4,5-diphenyl-2,3-dihydro-1H-pyrazolo[3,4-c]pyridazin-3-one4,5-diphenyl-2,3-dihydro-1H-pyrazolo[3,4-c]pyridazin-3-one
5-Methyl-6-(2-thienyl)-2,3,4,5-tetrahydropyridazin-3-one5-Methyl-6-(2-thienyl)-2,3,4,5-tetrahydropyridazin-3-one
6-(4-ethylphenyl)-3-(methylthio)-[1,2,4]triazolo[4,3-b]pyridazine6-(4-ethylphenyl)-3-(methylthio)-[1,2,4]triazolo[4,3-b]pyridazine
6-phenyl-4,5-dihydro-3(2h)-pyridazinone6-Phenyl-2,3,4,5-tetrahydropyridazin-3-one
6-phenyl-5-(1-piperidinyl)-2-prop-2-enyl-3-pyridazinone6-phenyl-5-(1-piperidinyl)-2-prop-2-enyl-3-pyridazinone
cep 26401irdabisant
cl 2188723-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
gsk 2126458A member of the class of quinolines that is quinoline which is substituted by pyridazin-4-yl and 5-[(2,4-difluorobenzene-1-sulfonyl)amino]-6-methoxypyridin-3-yl groups at positions 4 and 6, respectively. It is a highly potent inhibitor of PI3K and mTOR developed by GlaxoSmithKline and was previously in human phase 1 clinical trials for the treatment of idiopathic pulmonary fibrosis and solid tumors.omipalisib
ly2784544Gandotinib
minaprineminaprine
my 5445N-(3-chlorophenyl)-4-phenyl-1-phthalazinamine
N-(3,4-dichlorophenyl)-2-[4-(4-methoxyphenyl)-1-oxo-2-phthalazinyl]acetamideN-(3,4-dichlorophenyl)-2-[4-(4-methoxyphenyl)-1-oxo-2-phthalazinyl]acetamide
n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamideN-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide
N-(5-methyl-3-isoxazolyl)-2-[[6-(4-methylphenyl)-3-pyridazinyl]thio]acetamideN-(5-methyl-3-isoxazolyl)-2-[[6-(4-methylphenyl)-3-pyridazinyl]thio]acetamide
N-[2-(dimethylamino)ethyl]-2-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]acetamideN-[2-(dimethylamino)ethyl]-2-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]acetamide
N-[2-methoxy-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]-2-(4-methylphenoxy)acetamideN-[2-methoxy-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]-2-(4-methylphenoxy)acetamide
N-[3-[6-(1-azepanyl)-3-pyridazinyl]phenyl]-4-methylbenzenesulfonamideN-[3-[6-(1-azepanyl)-3-pyridazinyl]phenyl]-4-methylbenzenesulfonamide
N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]cyclohexanecarboxamideN-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]cyclohexanecarboxamide
N-cyclohexyl-2-[[6-(4-ethoxyphenyl)-3-pyridazinyl]thio]acetamideN-cyclohexyl-2-[[6-(4-ethoxyphenyl)-3-pyridazinyl]thio]acetamide
N,N-dimethyl-6-phenyl-3-pyridazinamineN,N-dimethyl-6-phenyl-3-pyridazinamine
pyridazinepyridazine
sulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.sulfachloropyridazine
sulfamethoxypyridazineA sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position.sulfamethoxypyridazine

Research

Studies (1,205)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990754 (62.57)18.7374
1990's112 (9.29)18.2507
2000's79 (6.56)29.6817
2010's200 (16.60)24.3611
2020's60 (4.98)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials41 (2.59%)5.53%
Reviews34 (2.15%)6.00%
Case Studies38 (2.40%)4.05%
Observational0 (0.00%)0.25%
Other1,469 (92.86%)84.16%