INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.
| Excerpt | Reference |
|---|
| "Therefore chronic osteomyelitis is prevalent in Nigerian children." | ( Dawodu, AH; Olusanya, AO; Oyemade, GA, 1977) |
| "Pyogenic vertebral osteomyelitis is a disease of adults that should be distinguished from true disk space infection." | ( Stauffer, RN, 1975) |
| "Chronic osteomyelitis is a devastating disease of unknown etiology." | ( Diktaban, G, 1992) |
| "Multifocal osteomyelitis is considered an uncommon complication of acute osteomyelitis." | ( Howman-Giles, R; Uren, R, 1992) |
| "Osteomyelitis are infections difficult to be completely cured, and its optimal therapy had not clearly been established." | ( Burgaleta, C; Messeguer, M; Peletier, R; Pernas, M; Velasco, GL, 1992) |
| "Osteomyelitis is a serious health problem that results in multiple limb amputations annually." | ( Schauwecker, DS, 1992) |
| "Coccidioidal osteomyelitis is difficult to diagnose." | ( Mishra, DD; Mohanty, A, 1991) |
| "Nocardial osteomyelitis is increasing in both immunocompetent and immunosuppressed patients." | ( Carbajosa, S; Carrero, P; Guiral, J; Refolio, C, 1991) |
| "Osteomyelitis is a common clinical problem that may be difficult to diagnose." | ( Ehrlich, LE; Iles, SE; Martin, RH; Saliken, JC, 1987) |
| "Osteomyelitis is becoming a more common infection." | ( Gentry, LO, 1987) |
| "Hematogenous osteomyelitis is usually diagnosed by an abnormal technetium Tc 99m diphosphonate bone scan in symptomatic patients who have positive blood cultures." | ( Mates, SM; Mikolich, DJ; Schlaeffer, F, 1987) |
| "Osteomyelitis is usually treated with wide surgical debridement and prolonged intravenous antibiotics." | ( Burdge, RE; Davenport, K; Perry, CR; Rice, SH; Ritterbusch, JK, 1986) |
| "acnes osteomyelitis is an adult male who has had prior surgery." | ( Noble, RC; Overman, SB, 1987) |
| "Subacute osteomyelitis is characterised by absence of symptoms of generalised infection and a favourable prognosis." | ( Claus, D; Delefortrie, G; Rombouts, JJ; Vincent, A, 1986) |
| "Fungal osteomyelitis is rare in patients who are not immunocompromised." | ( Brandt, SJ; Thompson, RL; Wenzel, RP, 1985) |
| "This unusual osteomyelitis is characteristically recurrent and multifocal with a predilection for the metaphyses." | ( Cyrlak, D; Pais, MJ, 1986) |
| "MRSA osteomyelitis is usually acquired by spread from a contiguous focus of infection and is often polymicrobic in nature." | ( Cierny, G; Mader, JT; Pennick, JJ; Sheftel, TG, 1985) |
| "H." | ( Reing, CM; Schwartz, RH, 1981) |
| "A case of chronic osteomyelitis is presented in which bone scintigraphy with Tc-99m-MDP provided more accurate information than radiography in demonstrating the extent of the sequestrum and the involucrum response." | ( Hemingway, DL; Lieberman, CM, 1980) |
| "Salmonella osteomyelitis is rare." | ( de Vogel, PL; van Cappelle, HG; Veenendaal, D, 1995) |
| "Vertebral osteomyelitis is an unusual complication of pneumococcal infection." | ( Duggan, JM; Kauffman, CA; Kutas, LM, 1995) |
| "Salmonella typhi osteomyelitis is an uncommon disease, usually associated with sickle cell anemia and other hemoglobinopathies, as well as with other disease states." | ( Carlson, DA; Dobozi, WR, 1994) |
| "Primary sternal osteomyelitis is a rare condition." | ( Bassaris, HP; Dougenis, D; Gogos, CA; Skoutelis, AT, 1993) |
| "Aspergillus osteomyelitis is rare, but the spine is most frequently affected." | ( D'Hoore, K; Hoogmartens, M, 1993) |
| "Contiguous osteomyelitis is a well recognized complication of pressure ulcers, but remains a challenging diagnostic and management problem." | ( Burdge, DR; Gribble, MJ, 1993) |
| "Osteomyelitis is a relatively infrequent manifestation of disseminated coccidioidomycosis." | ( Bickel, KD; Hovey, LM; Press, BH, 1993) |
| "Pelvic osteomyelitis is extremely rare in patients without predisposing factors." | ( Groeneweg, CE; Thurnheer, U, 1993) |
| "The incidence of osteomyelitis is significantly less when a nonvirulent strain of bacteria is substituted for a virulent strain." | ( Evans, RP; Harrison, BH; Nelson, CL, 1993) |
| "Chronic osteomyelitis is one of the most serious complications of orthopedic open fracture treatment." | ( Arm, DM; Bohach, GA; Price, JS; Tencer, AF, 1996) |
| "Pyogenic osteomyelitis is often accompanied by diabetes, but the disease in the clavicula has rarely been reported." | ( Kasamatsu, Y; Kondo, M; Nagata, H; Nakamura, Y; Yokoo, S; Yoshida, T; Yoshioka, K, 1997) |
| "Osteomyelitis is an inflammatory bone disease caused by pyogenic bacteria and involves the medullary cavity, cortex and periosteum." | ( Ramchandani, M; Robinson, D, 1998) |
| "Hematogenous osteomyelitis is a known complication of varicella." | ( Aebi, C; Ramilo, O, 1998) |
| "Early diagnosis of osteomyelitis is helpful for a successful conservative treatment." | ( Boulahdour, H; Hamissa, S; Kretz, S; Meignan, M; Montazel, JL; Perlemuter, L; Rahmouni, A; Vesco, L, 1999) |
| "Osteomyelitis is generally treated by the systemic administration of antibiotics and continuous irrigation after curettage of the lesion, and bone graft is performed secondarily to treat any bone defect." | ( Ishii, Y; Sasaki, S, 1999) |
| "However osteomyelitis is not uncommon with incidences as high as 14 p." | ( Aguiar, J; Lagarrigue, V; Meyers, WM; Portaels, F, 2000) |
| "Cervical osteomyelitis is uncommon." | ( Bernard, L; Carlier, RY; Faye, A; Frot-Martin, B; Morand-Blot, V; Vallée, C, 2001) |
| "If negative, osteomyelitis is unlikely." | ( Maugendre, D; Poirier, JY, 2001) |
| "Chronic osteomyelitis is a debilitating disease that is fairly common in developing countries." | ( Alonge, TO; Fashina, AN; Ogunlade, SO; Oluwatosin, A; Omololu, AB, 2002) |
| "Although osteomyelitis is a rare complication which may be caused by sepsis, or contamination during insertion, we speculate that adrenaline in high concentrations may promote the development of osteomyelitis and the drug should be applied cautiously in more diluted concentrations." | ( Boigner, H; Burda, G; Golej, J; Hermon, M; Stoll, E; Trittenwein, G, 2002) |
| "Bone infection or osteomyelitis is characterized by uncontrolled inflammation and destructive bone loss although little is known about immunopathogenesis of infection." | ( Friedland, JS; Wright, KM, 2002) |
| "Tuberculous osteomyelitis is characterized by uncontrolled inflammation leading to bone destruction." | ( Friedland, JS; Wright, KM, 2003) |
| "Osteomyelitis is a difficult problem for orthopaedic surgeons." | ( Ambrose, CG; Clyburn, TA; Gogola, GR; Mikos, AG; Peng, AS; Raymond, AK, 2003) |
| "Osteomyelitis is a familiar complication of sickle cell disease, and it may result in significant morbidity, especially when occurring in multiple sites." | ( Bibbo, C; Chang, V; Patel, DV; Sirkin, MS; Tyndall, WA, 2003) |
| "Salmonella osteomyelitis is rare in children and usually occurs in conjunction with haemoglobinopathies." | ( Haga, N; Iwaya, T; Nakamura, S; Takikawa, K, 2003) |
| "Diabetic foot osteomyelitis is among the most common and serious complications in patients with diabetes mellitus." | ( Bader, M; Jafri, AK; Krueger, T; Kumar, V, 2003) |
| "Cranial osteomyelitis is a common complication of brain surgery." | ( Asai, S; Kamei, Y; Torii, S, 2004) |
| "Metaphyseal osteomyelitis is a rarely described condition in small animals, especially the cat." | ( Bradley, WA, 2003) |
| "Pyomyositis and osteomyelitis are usually considered a late complication of advanced HIV disease." | ( Buckland, MS; Longhurst, HJ; Murphy, M, 2004) |
| "Subacute osteomyelitis is well known for diagnostic difficulty because of insidious nonspecific clinical courses and radiographic appearances mimicking various benign and malignant conditions." | ( Shih, HN; Shih, LY; Wong, YC, 2005) |
| "Osteomyelitis is a very rare association." | ( Desnoes, R; East-Innis, A; Gilbert, D; Shirley, S; Thame, K, 2005) |
| "Calcaneal osteomyelitis is uncommon and difficult to treat." | ( Alcaraz, P; Announ, N; Aubran, C; Chagnaud, C; Guis, S; Jaoua, S; Mattei, JP; Roudier, C; Roudier, J, 2006) |
| "Candidal vertebra osteomyelitis is a rare condition which occurs primarily in immunocompromised patients." | ( Akyurek, N; Erbaş, G; Gursel, T; Kaya, Z; Kocak, U; Tali, ET, 2005) |
| "Osteomyelitis is a recognised manifestation of melioidosis but Burkholderia pseudomallei is a relatively rare aetiological agent in musculoskeletal infections." | ( Kwan, MK; Merican, AM; Ng, WM, 2006) |
| "As soon as osteomyelitis is suspected, investigations with MRI and percutaneous biopsy should be performed followed by medical therapy." | ( Debnath, UK; Fares, Y; Khazim, RM, 2006) |
| "Osteomyelitis is an infection of the bone and successful treatment involves the removal of the affected bone and the tissue by a surgical procedure following prolonged systemic and local antibiotic therapy for 4 to 6 weeks." | ( Fu, YC; Guan Lee, HC; Lee, DJ; Naraharisetti, PK; Wang, CH, 2006) |
| "Osteomyelitis is an extremely unusual complication of invasive otitis externa." | ( Boulaïch, M; Filali, A; Jamal, H; Kzadri, M; Lazrak, A; Nazih, N; Oujilal, A, 2006) |
| "Diabetic foot osteomyelitis is a serious disease in view of its site and the microorganisms involved, which are often multidrug-resistant." | ( Beytout, J; Bonnet, R; Couret, G; Desbiez, F; Laurichesse, H; Lesens, O; Tauveron, I; Thieblot, P, 2007) |
| "Osteomyelitis is a common clinical manifestation of chronic granulomatous disease, a disorder of phagocytic function." | ( Braverman, RM; Davis, CM; Dishop, MK; Noroski, LM; Paul, ME; Rosenblatt, HM; Sutton, DA, 2007) |
| "Tubercular osteomyelitis is clinically and radiologically indistinguishable from pyogenic osteomyelitis, and the two conditions can be differentiated only on the basis of histopathological evaluation of involved tissue." | ( Agarwal, AK; Gupta, A; Nigam, S; Sethi, A; Sethi, D, 2008) |
| "Osteomyelitis is an inflammatory bone disease caused by pyogenic bacteria." | ( Baddour, MM; El-Kamel, AH, 2007) |
| "Tubercular sternal osteomyelitis is a rare manifestation of tuberculosis." | ( Howell, JM; Mohammadi, A, 2009) |
| "Osteomyelitis is the inflammation of bone secondary to infection with pyogenic organisms." | ( Farooqi, BJ; Hashmi, I; Rafi, S; Sabir, N, 2007) |
| "Osteomyelitis is a relatively frequent bacterial infection of the jaw bones." | ( Brutto, D; Cappello, V; Carlino, V; Consolo, G; Marescalco, M; Mauro, M; Pappalardo, S; Tanteri, L, 2008) |
| "Osteomyelitis is a progressive infectious process resulting in inflammatory destruction and necrosis of bone." | ( Kobayashi, S; Miyamoto, K; Nomura, M; Sakura, N; Takahashi, T; Yokogawa, K, 2008) |
| "Osteomyelitis is an inflammatory disease of the bone that is characterized by the presence of necrotic bone tissue and increased osteoclast activity." | ( Hudson, MC; Marriott, I; Ritchie, S; Sahraei, M; Somayaji, SN, 2008) |
| "Osteomyelitis is a difficult to treat bacterial infection of the bone." | ( Arhin, FF; Caron, L; Delorme, D; Dietrich, E; Fadhil, I; Ferreira, SS; Houghton, TJ; Kang, T; Laquerre, K; Lehoux, D; Liu, J; Moeck, G; Ostiguy, V; Parr, TR; Poirier, H; Rafai Far, A; Sarmiento, I; Tanaka, KS; Viens, F, 2008) |
| "Osteomyelitis is an infection located in bone and a notoriously difficult disease to manage, requiring frequent and heavy doses of systemically administered antibiotics." | ( Arhin, FF; Delorme, D; Dietrich, E; Fadhil, I; Far, AR; Ferreira, SS; Houghton, TJ; Kang, T; Lafontaine, Y; Laquerre, K; Lehoux, D; Liu, J; Moeck, G; Ostiguy, V; Parr, TR; Poirier, H; Sarmiento, I; Tanaka, KS; Viens, F, 2008) |
| "Cranial osteomyelitis is a potentially fatal lesion." | ( Bruni, C; Padovano, F; Schillaci, O; Simonetti, G; Travascio, L, 2008) |
| "Osteomyelitis is an inflammatory process involving cortical and cancellous bone." | ( Feichtinger, M; Kärcher, H; Pau, M; Zemann, W, 2011) |
| "Osteomyelitis is an inflammation of the bone caused by infecting organisms." | ( Brncic, N; Gulan, G; Jotanovic, Z; Jurdana, H; Ravlic-Gulan, J; Sestan, B, 2010) |
| "Osteomyelitis is a severe bone infection frequently caused by Staphylococcus aureus, which shows significant resistance to methicillin." | ( Amador, G; Bouler, JM; Gautier, H; Merle, C; Plumecocq, A; Weiss, P, 2012) |
| "Osteomyelitis is one of the most serious infectious problems in the orthopedic field." | ( Aizawa, S; Goto, B; Harada, T; Horaguchi, T; Iriuchishima, T; Nagai, Y; Saito, A; Tokuhashi, Y, 2011) |
| "The diagnosis of osteomyelitis is a challenge for diagnostic imaging." | ( Amthauer, H; Chossat, F; Dahmane, A; Ivancevic, V; Lang, O; Le Guludec, D; Meller, J; Richter, WS; Schwenke, C; Signore, A; Szilvazi, I, 2011) |
| "Early osteomyelitis is a challenging diagnosis clinically and radiologically in patients with sickle cell disease, which can be diagnosed on M." | ( Ahmad, S; Khan, ZA; Rehmani, R; Sheikh, MY, 2010) |
| "Vertebral osteomyelitis is one of the most common forms of Aspergillus osteomyelitis." | ( Chen, XS; Weng, XH; Wu, JQ; Yang, FF; Zhu, LP, 2011) |
| "Osteomyelitis is a debilitating infectious disease of the bone." | ( Claro, T; Foster, TJ; Kerrigan, SW; Miajlovic, H; O'Brien, FJ; O'Seaghdha, M; Widaa, A, 2011) |
| "The diagnosis of osteomyelitis is a key step of diabetic foot management." | ( İpcioğlu, OM; Mutlu, H; Mutluoğlu, M; Özcan, Ö; Sildiroglu, O; Turhan, V; Uzun, G; Yildiz, S, 2011) |
| "Osteomyelitis is an uncommon infection that is considered to be a childhood disease." | ( Gil-Albarova, J; Gómez-Palacio, VE; Herrera, A, 2012) |
| "Chronic osteomyelitis is still common in developing countries like Nigeria due to the fact that conditions associated with the lowering of resistance to infections like malnutrition, malaria, anaemia, and acute eruptive fever are still prevalent in our society." | ( Alonge, TO; Obiechina, AE; Okoje, VN, 2011) |
| "Cryptococcal osteomyelitis is extremely rare and almost always occurs in immunocompromised patients." | ( Tang, ZH; Yu, YS; Zang, GQ; Zhang, Y, 2012) |
| "Candida osteomyelitis is a rare infection." | ( Horn, DL; Keith, SW; Slenker, AK, 2012) |
| "Pelvis osteomyelitis is rare in childhood." | ( Campanacci, D; Canessa, C; Chiappini, E; Maglione, M; Resti, M; Trapani, S, 2011) |
| "Candida osteomyelitis is a well recognized but infrequent entity." | ( Alfonso, M; Bustos, C; Del Pozo, JL; Quintana, J; Rubio, M; Villas, C; Yuste, JR, 2012) |
| "Cryptococcal osteomyelitis is itself an extremely rare diagnosis, and the unique presentation with concurrent cryptococcal meningitis in our patient with lymphoma was likely due to his PEP-C treatment." | ( Brown, JM; Fan, AC; Felsher, DW; Fischbein, NJ; Howard, W; Hsieh, RW; McClellan, JS; To, CA, 2012) |
| "Osteomyelitis is a complex and heterogeneous group of infections that require surgical and antimicrobial interventions." | ( Chaves, RL; Gargalianos-Kakolyris, P; Heep, M; Malizos, KN; Pathan, R; Petrelli, E; Santantonio, T; Seaton, RA; Viale, P, 2013) |
| "Chronic osteomyelitis is a challenging setback to the orthopedic surgeons in deciding an optimal therapeutic strategy." | ( Basu, D; Bhattacharya, R; Kundu, B; Nandi, SK, 2013) |
| "Calcaneal osteomyelitis is a surgical diagnosis that may be treated by local, resection or major amputation." | ( Walsh, TP; Yates, BJ, 2013) |
| "Candida Osteomyelitis is uncommon." | ( Eves, S; Potter, M; Sayeed, R, 2014) |
| "This type of osteomyelitis is uncommon, and in the immunocompetent host, is more often related to a chronic evolution following direct inoculation of the microorganism." | ( Cicero, A; Colin, C; Franco-Cendejas, R; Hernández, M; López-Jácome, E; Vanegas, S, 2014) |
| "Xanthogranulomatous osteomyelitis is a rare inflammatory process characterized histologically by collection of foamy macrophages admixed with mononuclear cells." | ( Cui, XJ; Han, JK; Wang, YL; Yu, H; Zhang, H, 2014) |
| "Osteomyelitis is a severe orthopaedic complication which is difficult to diagnose and treat." | ( Arts, JJ; Brans, BT; Odekerken, JC; Walenkamp, GH; Welting, TJ, 2014) |
| "Osteomyelitis is a common manifestation of invasive Staphylococcus aureus infection characterized by bone loss and destruction." | ( Chen, Q; Hou, T; Luo, F; Wu, X; Xie, Z; Xu, J, 2014) |
| "Osteomyelitis is a potential fatal disease process that requires accurate diagnosis and medical management." | ( Hawkins, AP; Kirages, D; Sahai-Srivastava, S; Sigman, E; Sum, JC, 2015) |
| "Osteomyelitis is characterised by weakened bones associated with progressive bone loss." | ( Claro, T; Foster, TJ; Kavanagh, N; Kerrigan, SW; O'Brien, FJ, 2015) |
| "Osteomyelitis is a progressive destruction of bones caused by microorganisms." | ( Boratto, FA; Cardoso, VN; Fernandes, SO; Ferreira, Ddos S; Ferreira, LA; Oliveira, MC; Serakides, R, 2015) |
| "Candida albicans osteomyelitis is a rare disease that occurs in immunocompromised individuals, sometimes with a late diagnosis related to the mismatch between symptoms and candidemia." | ( Cortez, J; Magano, R; Ramos, E; Trindade, L, 2015) |
| "Pedal osteomyelitis is a worrisome complication of diabetic foot disease." | ( Alavi, A; Rubello, D; Yang, H; Zhuang, H, 2016) |
| "Osteomyelitis is a serious infection predominantly caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA)." | ( Gaudias, J; Hamed, K; Malizos, K; Menichetti, F; Militz, M; Pathan, R; Riccio, G; Sarma, J; Seaton, RA; Trostmann, U, 2016) |
| "Although Salmonella osteomyelitis is commonly seen in immunocompromised patients, it may occasionally affect an immunocompetent host." | ( Mohan, S; Roy, S; Shrestha, P, 2015) |
| "Osteomyelitis is still considered to be one of the major challenges for orthopedic surgeons despite advanced antiseptic surgical procedures and pharmaceutical therapeutics." | ( Kwon, OS; Lee, IS; Lee, JH; Oh, EJ; Oh, SH, 2016) |
| "Osteomyelitis is not an uncommon emergency department diagnosis in pediatric patients, and most cases are in the lower extremities." | ( Kienstra, AJ; Wallin, D, 2016) |
| "Chronic osteomyelitis is difficult to be cured and often relapses, which presents to be a great challenge to clinicians." | ( Cheng, Z; Wu, G; Wu, W; Ye, C; Zheng, Q, 2016) |
| "Rib osteomyelitis is a rare entity, occurring in approximately 1 % or less of all cases of haematogenous osteomyelitis." | ( Borzani, I; Esposito, S; Giannitto, C; Pinzani, R; Principi, N; Raffaeli, G, 2016) |
| "Treatment of osteomyelitis is confounded by widespread antimicrobial resistance and the propensity of bacteria to trigger pathological changes in bone remodeling that limit antimicrobial penetration to the infectious focus." | ( Cassat, JE; Guelcher, SA; Hammer, ND; Hendrix, AS; Putnam, NE; Skaar, EP; Snyder, DJ; Spoonmore, TJ; Wilde, AD, 2016) |
| "Osteomyelitis is an infectious process in bone that occasionally leads to bone destruction." | ( Alizadeh, C; Artiaco, S; Arts, JJ; Bialecki, J; Brychcy, A; Domenico, A; Drago, L; Geurts, J; Hyvönen, P; Juutilainen, V; Lindfors, N; Romanò, CL; Suda, AJ, 2017) |
| "Osteomyelitis is a major problem worldwide and is devastating due to the potential for limb-threatening sequelae and mortality." | ( Bakhshalian, N; Bartoszewicz, M; Ebetino, FH; Junka, AF; Lundy, MW; Mahabady, S; McKenna, CE; Neighbors, JD; Oleksy, M; Richard, E; Russell, RG; Sadrerafi, K; Sedghizadeh, PP; Sun, S; Szymczyk, P; Tjokro, N, 2017) |
| "Chronic osteomyelitis is a prolonged persistent disease accompanied by bone destruction and sequestrum formation, it is very difficult to treat." | ( Chen, C; Gu, H; He, X; Huang, W; Jiang, J; Li, J; Liu, W; Wang, Q; Zhang, D; Zhou, N, 2017) |
| "Skull base osteomyelitis is an uncommon disease that usually complicates a malignant external otitis with temporal bone involvement." | ( Conde-Díaz, C; Gutiérrez, F; Llenas-García, J; Masiá, M; Parra Grande, M; Terol Esclapez, G, 2017) |
| "Skull base osteomyelitis is a life-threating condition; clinical suspicion and correct microbiological identification are key to achieve an accurate and timely diagnosis." | ( Conde-Díaz, C; Gutiérrez, F; Llenas-García, J; Masiá, M; Parra Grande, M; Terol Esclapez, G, 2017) |
| "Chronic osteomyelitis is a chronic inflammatory disease induced by bone infection." | ( Frippiat, F; Gillet, P; Kabore, C; Wouters, A, 2017) |
| "vertebral osteomyelitis is rare." | ( Bouaziz, M; Chaabane, I; Kilani, B; Ladeb, F; Tiouiri, HB; Zayet, S, 2017) |
| "Osteomyelitis is an inflammation of bone caused by invading organisms." | ( Chai, Y; Wen, G; Weng, Z; Wu, T; Xu, J; Yu, Y, 2018) |
| "Salmonella osteomyelitis is an uncommon complication of salmonella infection, especially the salmonella vertebral osteomyelitis (SVO)." | ( Cheng, W; Feng, W; Li, T; Lian, K; Lin, D; Luo, D; Xian, H, 2018) |
| "Chronic osteomyelitis is caused by bacterial infection of the bone and is a major problem in orthopaedic surgery." | ( Arts, JJC; Geurts, JAP; van Vugt, TAG; Walraven, JMB, 2018) |
| "Osteomyelitis is a well-known bone infection in humans." | ( Tang, T; Wang, Y; Xia, D; Xia, Y; Xu, S; Zhang, H; Zhou, P, 2019) |
| "Salmonella osteomyelitis is extremely rare; only a few cases have been reported in healthy adults." | ( Akagi, M; Hashimoto, K; Iemura, S; Nishimura, S, 2018) |
| "Osteomyelitis is an acute or chronic inflammatory process of the bone following infection with pyogenic organisms like Staphylococcus aureus." | ( Abba, Y; Karunanidhi, A; Lulu, GA; Mohamad Yusof, L; Mohd Fauzi, F; Othman, F, 2018) |
| "Clival osteomyelitis is a life-threatening complication of untreated malignant otitis externa or paranasal sinus infection." | ( Abou-Al-Shaar, H; Alzhrani, G; Couldwell, WT; Gozal, YM; Mulvaney, GG; Oakley, GM, 2019) |
| "Osteomyelitis is an infection in a bone." | ( Anno, T; Irie, S; Kaku, K; Kaneto, H; Kawasaki, F; Okimoto, N; Shigemoto, R, 2019) |
| "Candida osteomyelitis is a debilitating disease that is difficult to diagnose and treat." | ( Agadakos, E; Chatziioannou, S; Gamaletsou, MN; Katsimpoulas, M; Kostomitsopoulos, N; Meletiadis, J; Panayiotides, IG; Petraitis, V; Sipsas, NV; Walsh, TJ, 2019) |
| "Chronic osteomyelitis is difficult to treat, with biofilm growth and the diffusion barrier to antibiotics presented by bone contributory factors." | ( Bowker, KE; Lovering, AM; MacGowan, AP; Nelson, SM; Sweeney, E, 2019) |
| "Osteomyelitis is often challenging to treat." | ( Guervil, DJ; Johnson, LB; Ramani, A, 2019) |
| "Osteomyelitis is characterized by a series of microbial invasion, vascular disruption, bony necrosis, and sequestrum formation due to impaired host defense response." | ( Baik, SC; Byun, JH; Byun, SH; Hwang, DS; Hwang, SC; Kang, YH; Kim, HY; Kim, MJ; Kim, SH; Lee, HC; Lee, HJ; Oh, SH; Park, JS; Rho, GJ, 2019) |
| "Implant-associated osteomyelitis is a chronic infection that complicates orthopaedic surgeries." | ( Awad, HA; de Mesy Bentley, KL; Kate, SL; Schwarz, EM; Trombetta, RP, 2019) |
| "Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role." | ( Álvarez, V; Asensi, V; Carton, JA; Fierer, J; Meana, Á; Montes, AH; Ocaña, MG; Pérez-Is, L; Valle-Garay, E, 2019) |
| "Chronic osteomyelitis is a challenging condition to treat and although no exact treatment guidelines exist, the surgical management strategy includes wide resection of necrotic and infected bone followed by dead space management." | ( Ferreira, N; Oosthuysen, W; Tanwar, Y; Venter, R, 2020) |
| "Osteomyelitis is an inflammatory bone disease caused by infection microorganisms which leads to progressive bone destruction and loss." | ( Qiu, Y; Shen, K; Shi, M; Xiao, Y; Yuan, Q; Zhang, P; Zhang, Y; Zhao, Q, 2020) |
| "Mandibular osteomyelitis is common in domestic and wild ruminants." | ( Ganter, M; Meilwes, JM; Punsmann, TM; Schwennen, C; Wagener, MG, 2020) |
| "Fungal osteomyelitis is a rare disease which usually presents in an indolent manner." | ( Bhaskaran, V; Chandran, S; Dinesh, K; Khan, S; Kumar, A, 2019) |
| "Chronic osteomyelitis is a relapsing, persistent, low-grade inflammation of bone caused by various infectious agents." | ( Bhat, SN; Chawla, K; Mukhopadhyay, C; Shenoy, PA; Vishwanath, S, 2020) |
| "In general, osteomyelitis is treated with antibiotics, and in severe cases, the inflammatory bone tissue is removed and substituted with poly (methyl methacrylate) (PMMA) beads containing antibiotics." | ( Ahn, CB; Baik, JM; Choi, ES; Kim, JH; Lee, JH; Lee, JW; Son, KH; Yu, YS, 2020) |
| "Osteomyelitis is an infection involving bone." | ( Alzueta, N; Castresana, M; Echeverria, A; Gascón, A; Marin, M; Pío, M, 2021) |
| "Osteomyelitis is a progressive inflammatory disease requiring prolonged systemic treatment with high antibiotic doses, and is very challenging to be treated." | ( Abdeltawab, NF; Awad, GAS; Ishak, RAH; Nasr, M; Radwan, NH, 2020) |
| "Osteomyelitis is a bone marrow infection which generally involves cortical plates and which may occur after bone trauma, orthopedic/maxillofacial surgery or after vascular insufficiency episodes." | ( Chindamo, G; Chirio, D; Gallarate, M; Peira, E; Sapino, S, 2021) |
| "Osteomyelitis is a rare initial presentation of HIV." | ( Lantion-Ang, FL; Reyes, PVSJ; Santos, NJC; Tomacruz, IDV, 2020) |
| "Osteomyelitis is a complex disease in orthopedics mainly caused by bacterial pathogens invading bone or bone marrow." | ( Deng, H; Jin, L; Luo, Y; Ma, S; Tao, F; Tao, H; Xiang, W; Zheng, J, 2021) |
| "Mycobacterial osteomyelitis is rare, difficult to diagnose and treat, and may necessitate prolonged interruption of anti-leukemic therapy." | ( Chan, WY; Ha, SY; Ho, KW; Ho, PL; Lam, AY; Lau, TW; So, NL; To, KK, 2021) |
| "Osteomyelitis is a debilitating infection of bone that results in substantial morbidity." | ( Cassat, JE; Duvall, CL; Ford, CA; Guelcher, SA; Gupta, MK; Spoonmore, TJ, 2021) |
| "Rib osteomyelitis is a rare disease, comprising 1% or less of all osteomyelitis." | ( Mitsui, S; Mizuki, S; Tauchi, S; Tobe, S, 2021) |
| "Skull base osteomyelitis is 1 of the complications of a middle ear infection seen mainly in immunocompromised individuals." | ( Bhattacharya, A; Krishnaraju, VS; Kumar, R; Mittal, BR; Patro, SK; Singh, H, 2021) |
| "Osteomyelitis is characterized by progressive inflammatory bone destruction accompanied by severe pain and disability." | ( Fujita, R; Hamano, H; Hiratsuka, S; Iwasaki, N; Kobayashi, H; Sato, D; Shimizu, T; Takahata, M, 2022) |
| "Osteomyelitis is bacterial infection of bone, commonly caused by Staphylococcus aureus." | ( Gao, L; Li, T; Tang, Z; Wang, J, 2021) |
| "Osteomyelitis is an infection of the bone marrow." | ( Banks, JS; Labiste, CC; McElroy, E; Subhawong, TK, 2022) |
| "Osteomyelitis is an inflammatory process of bone and bone marrow that may even lead to patient death." | ( Aguilera-Correa, JJ; Carias-Cálix, RA; Esteban, J; Gisbert-Garzarán, M; Jiménez-Jiménez, C; Mediero, A; Vallet-Regí, M, 2022) |
| "Chronic osteomyelitis is a challenging disease due to its serious rates of mortality and morbidity while the currently available treatment strategies are suboptimal." | ( Elkayal, M; Elkheshen, SA; Shamma, RN; Wassif, RK, 2021) |
| "Candida osteomyelitis is uncommon, especially after dog bites." | ( Ceccarelli, G; Cera, G; De Meo, D; Di Bari, S; Gavaruzzi, F; Raponi, G; Villani, C, 2022) |
| "Osteomyelitis is considered as the most serious bone infection, which can lead to the bone destruction or fatal sepsis." | ( Feng, X; Lei, C; Lei, J; Li, G; Liang, H; Liu, X; Ma, L; Ouyang, Q; Tan, L; Yang, C; Zeng, Y, 2022) |
| "Salmonella osteomyelitis is a well-known complication of hemoglobinopathies but is unusual in healthy individuals." | ( Habeck, C; Mayer, J; Weiner, S; Willen, J, 2021) |
| "Osteomyelitis is an acute or chronic inflammatory bone disease with a high disability rate." | ( Guo, QF; Huang, K; Lin, BY; Liu, YY; Ma, GP; Wang, LJ; Yu, HJ; Yu, M, 2022) |
| "Osteomyelitis is commonly developed via hematogenous spreading or direct inoculation of bacteria from orthopedics trauma." | ( Chen, B; Chen, G; Gao, X; Hu, J; Lin, B; Wang, M; Zhang, C; Zhang, S, 2022) |
| "Osteomyelitis is a potentially devastating inflammatory bone disease that leads to bone destruction and loss." | ( Hayashi, K; Ishikawa, K; Kishida, R; Shimabukuro, M; Tsuchiya, A, 2022) |
| "Treatment of osteomyelitis is still challenging, as conventional antibiotic therapy is limited by the emergence of resistant strains and the formation of biofilms." | ( Chen, G; He, Z; Hu, H; Jin, X; Lu, F; Song, X; Sun, J; Wu, X; Zhang, J, 2022) |
| "Osteomyelitis is a difficult-to-treat infectious disease." | ( Cheng, X; Peng, C; Ren, G; Wang, Q; Wang, Y; Yuan, B; Zhang, Y; Zhou, S, 2022) |
| "Osteomyelitis is a hard-to-treat infection of the bone and bone marrow that is mainly caused by Staphylococcus aureus, with an increasing incidence of methicillin-resistant S." | ( Aguilera-Correa, JJ; de-Pablo-Velasco, D; Esteban, J; Fernández-Aceñero, MJ; Gisbert-Garzarán, M; Lozano, D; Mediero, A; Vallet-Regí, M, 2022) |
| "Salmonella osteomyelitis is rare in patients without sickling hemoglobinopathies." | ( Chattaway, MA; Godbole, G; Hurt, W; Hutchinson, J; Stephenson, J, 2023) |
| "Among these, osteomyelitis is inflammation of the bone caused by the invasion of the bacterial pathogen in the bones." | ( Guo, X, 2023) |
| "Osteomyelitis is an infection of the bone, associated with an inflammatory process." | ( Aguilera-Correa, JJ; Bouza, E; Cussó, L; de Pablo, D; Desco, M; Esteban, J; Fernández Aceñero, MJ; González-Arjona, M; Muñoz, P; Salinas, B, 2023) |
| "Osteomyelitis is a bone inflammation that can be related to various infectious agents." | ( Ampadiotaki, MM; Diamantopoulou, K; Georgousi, K; Gourtzelidis, G; Kokkinis, C; Lelekis, M; Pallis, D; Papadakis, SA; Tatakis, F; Tsivelekas, K, 2023) |
| "Osteomyelitis is infected condition of bone by micro-organisms." | ( Gao, L; Li, T; Tang, Z; Wang, J, 2023) |
| "Osteomyelitis is a frequent complication of diabetic foot ulcers, since bacteria can contiguously spread from soft tissues to the bone, involving the cortex first and then the bone marrow." | ( Doukanaris, PT; Neofytou, MS; Papaetis, GS; Stylianou, ES, 2023) |
| Excerpt | Reference |
|---|
| "Suction-irrigation in the treatment of acute osteomyelitis in children does not appear to be essential for successful management, and introduces added risks of superinfection and technical complications." | ( Letts, RM; Wong, E, 1975) |
| "A new therapeutic principle in the treatment of osteomyelitis is introduced-as an alternative to "Suction Drainage"-, i." | ( Kantor, H, 1978) |
| "In 41% of all patients operative treatment for osteomyelitis was necessary (37% sequesterectomies, 44% stabilisations with fixateur externe)." | ( Bartsch, C; Peters, KM; Zilkens, KW, 1992) |
| "Long-term follow-up of patients treated for osteomyelitis outcome has not been done in sufficient detail to be certain of the comparative results of different antimicrobials." | ( Tice, AD, 1991) |
| "Cefadroxil has been used for the treatment of acute osteomyelitis." | ( Jackson, DS; Nahata, MC; Powell, DA, 1990) |
| "In spite of prompt antibiotic treatment, osteomyelitis of the compressed T12 was recognized 5 weeks later." | ( DaSilva, RM; Fellmeth, BD; Spengler, DM, 1988) |
| "We have diagnosed and treated 17 cases of osteomyelitis of the skull base." | ( Chandler, JR; Grobman, L; Quencer, R; Serafini, A, 1986) |
| "In the treatment of osteomyelitis, flap coverage provides the necessary blood supply for healing." | ( Scharnagl, E, 1986) |
| "This method was applied in the treatment of osteomyelitis in 14 patients whose duration of symptoms ranged from one month to 22 years." | ( Burdge, RE; Davenport, K; Perry, CR; Rice, SH; Ritterbusch, JK, 1986) |
| "After successful antibiotic treatment of the osteomyelitis, the clinical and pathologic findings of amyloidosis disappeared." | ( Brungardt, G; Dunn, M; Hornbaker, S, 1986) |
| "The standard method of treating osteomyelitis generally consists of irrigation and debridement supplemented by pre- and postoperative antibiotics and intraoperative antimicrobial solutions." | ( Galloway, KP; Henry, SL, 1995) |
| "Conservative treatment of osteomyelitis at the C1-C2 level can be efficacious in the correct setting." | ( Ethier, R; Lam, CH; Pokrupa, R, 1996) |
| "A 39-year-old woman being treated for osteomyelitis with vancomycin developed severe neutropenia and drug fever." | ( Smith, PF; Taylor, CT, 1999) |
| "HAC is an effective adjuvant in treating chronic osteomyelitis in a rat model when using a void-fill placement technique." | ( Baumgaertner, MR; Gutow, AP; Solberg, BD, 1999) |
| "Antibiotic classes used in the treatment of osteomyelitis include penicillins, beta-lactamase inhibitors, cephalosporins, other beta-lactams (aztreonam and imipenem), vancomycin, clindamycin, rifampin, aminoglycosides, fluoroquinolones, trimethoprim-sulfamethoxazole, metronidazole, and new investigational agents including teicoplanin, quinupristin/dalfopristin, and oxazolidinones." | ( Bergquist, SC; Calhoun, J; Mader, JT; Shirtliff, ME, 1999) |
| "Implants to prevent or treat osteomyelitis are described, composed of phosphate/poly(d,l-lactide) blends containing the antibiotic gentamicin." | ( Evora, C; Soriano, I, 2000) |
| "Therefore, oral gatifloxacin treatment of osteomyelitis may be an effective alternative to intravenous nafcillin treatment." | ( Calhoun, JH; Mader, JT; Shirtliff, ME, 2002) |
| "Conventional treatment of osteomyelitis involves the repeated surgical removal of dead bone tissue coupled with repeated irrigation of the wound and prolonged systemic administration of antibiotics." | ( Ahmed, K; El-Ghannam, A; Omran, M, 2005) |
| "Second, we were successful in treating 2 cases of osteomyelitis and prosthesis infection with VCM-impregnated CPC." | ( Ishibashi, Y; Katano, H; Nagumo, A; Sasaki, T; Toh, S, 2005) |
| "aureus make successful treatment of osteomyelitis difficult." | ( Ellington, JK; Harris, M; Hudson, MC; Sherertz, R; Vishin, S; Webb, LX, 2006) |
| "The child responded nicely to the treatment for acute osteomyelitis and congenital hypofibrinogenemia." | ( Bagchi, S; Datta Kanjilal, S, 2006) |
| "The use of fluoroquinolones for treatment of MDRVS osteomyelitis has not been established." | ( Ang, JY; Asmar, BI, 2008) |
| "The value of fluoroquinolones for the treatment of osteomyelitis lies in the fact that they can be administered in an outpatient setting." | ( Falagas, ME; Karamanis, EM; Matthaiou, DK; Moraitis, LI, 2008) |
| "The results of the surgical treatment of osteomyelitis with expandable titanium cages and either allograft or autograft are presented." | ( Chou, D; Lu, DC; Wang, V, 2009) |
| "It is difficult to treat chronic osteomyelitis due to the formation of the Staphylococcus aureus biofilms." | ( Ding, J; Fan, X; Li, G; Li, J; Lin, Y; Mei, L; Tang, H; Tang, X; Xu, Y; Yang, J; You, Y; Zhao, W; Zhao, X, 2010) |
| "Six children received PET/CT after treatment of acute osteomyelitis." | ( Bares, R; Dittmann, H; Fuchs, J; Schäfer, JF; Seitz, G; Warmann, SW, 2011) |
| "The VBC is effective in treating chronic osteomyelitis of rabbit by providing a sustained release of vancomycin, in addition to stimulating bone regeneration, so it may be a promising biomaterial for treating chronic osteomyelitis." | ( Cui, X; Huang, W; Jia, W; Wang, X; Zhang, C; Zhao, C, 2012) |
| "Antibiotic treatment of osteomyelitis with the current degradable and non-degradable delivery devices is effective in the majority of cases." | ( Busscher, HJ; Kluin, OS; Neut, D; van der Mei, HC, 2013) |
| "Surgery is usually used to treat diabetic foot osteomyelitis (DFO), whether primarily or in cases in which antibiotics are not able to control infection." | ( Aragón-Sánchez, J; Cabrera-Galván, JJ; Hernández-Herrero, MJ; Lázaro-Martínez, JL; Quintana-Marrero, Y; Sanz-Corbalán, I, 2013) |
| "In total, 220 patients were treated for osteomyelitis; the population was predominantly elderly, with predisposing baseline conditions such as diabetes and chronic renal/cardiac diseases." | ( Chaves, RL; Gargalianos-Kakolyris, P; Heep, M; Malizos, KN; Pathan, R; Petrelli, E; Santantonio, T; Seaton, RA; Viale, P, 2013) |
| "In the conventional treatment of osteomyelitis, the penetration of antibiotics into the infected bone is commonly poor." | ( Chia, WT; Chung, MF; Hsiao, CW; Hsiao, HC; Liu, HY; Sung, HW; Yang, CM, 2014) |
| "Clinical effect of treating long bone osteomyelitis with Masquelet technology and the possible effects of vancomycin in different doses on knitting were also evaluated in follow-up visit lasting for 6~18 months, and 22 cases' bone was healed on imaging at the last follow up." | ( Gao, S; Luo, J; Su, Y; Tian, S; Yang, G, 2015) |
| "Twenty-four patients treated for osteomyelitis of the cervical spine are presented." | ( Hao, DJ; Li, T; Zhang, ZX, 2016) |
| "This single-stage surgical treatment for osteomyelitis of the cervical spine provided satisfactory results." | ( Hao, DJ; Li, T; Zhang, ZX, 2016) |
| "This was accomplished in the course of treating osteomyelitis patients, using a combination of long-term (6 weeks), outpatient, intravenous (IV) an- tibiotics administered through a femoral central line." | ( Coulson, A; Haugen, D; Peek, A, 2016) |
| "The obstacles faced to treat chronic osteomyelitis infection clinically led to the search for an ideal biomaterial, resulted in combining two major aspects of bone tissue engineering namely surface modified metallic implant and polymer nanocomposite scaffold." | ( David, N; Nallaiyan, R, 2018) |
| "Recent case series suggest success in treating osteomyelitis of the foot with CAS in a mean time to healing of 4 months; however, few studies with a control group for comparison exist." | ( Dekker, AP; Scammell, B; Uzoho, C, 2019) |
| "The traditional treatment for osteomyelitis, which involves antibiotics and debridement, does not provide a complete solution for infection and bone repair." | ( Cai, D; Diao, L; Hu, Y; Shen, A; Tao, J; Wang, L; Yang, Y; Zhang, Y, 2020) |
| "Next-generation treatment strategies to treat osteomyelitis with complete eradication of pathogen at the bone nidus and prevention of emergence of drug resistance is a real challenge in orthopedics." | ( Kumar, A; Panjla, A; Qayoom, I; Teotia, AK; Verma, S, 2020) |
| "Indications for surgical treatment of rib osteomyelitis remain unclear, however, because of few reported cases." | ( Mitsui, S; Mizuki, S; Tauchi, S; Tobe, S, 2021) |
| "Currently, the treatment of osteomyelitis poses a great challenge to clinical orthopedics." | ( Li, P; Li, S; Li, Z; Lou, J; Shi, X; Wang, J; Wang, X; Xu, B; Yang, C; Zhen, P, 2022) |