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aporphine alkaloid

Any benzylisoquinoline alkaloid that has a structure based on 4H-dibenzo[de,g]quinoline or its 3-methyl derivative.

ChEBI ID: 134209

Members (23)

MemberDefinitionRole
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol
1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
10,11-dihydroxy-n-allylnoraporphine(8R)-7-prop-2-enyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
actinodaphineAn organic heteropentacyclic compound 6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline bering additional hydroxy and methoxy substituents at positions 10 and 11 respectively.actinodaphnine
anonaineAn aporphine alkaloid that exhibits anti-cancer, trypanocidal and antiplasmodial activites.(-)-annonaine
apomorphineapomorphine
aporphineAn isoquinoline alkaloid that is the N-methyl derivative of 5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline.aporphine
asimilobineR-(-)-asimilobine
boldineBoldine
bulbocapnineAn aporphine alkaloid that has been isolated from Corydalis and exhibits inhibitory activity against enzymes such as tyrosine 3-monooxygenase and diamine oxidase.bulbocapnine
corytuberineAn aporphine alkaloid that is aporphine which is substituted by hydroxy groups at positions 1 and 11, and by methoxy groups at positions 2 and 10 (the S enantiomer).(S)-corytuberine
dicentrineDicentrine
glaucineAn aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups.(S)-glaucine
isocorydineIsocorydine
isoteolinIsoboldine
laurolitsineAn aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase.laurolistine
magnoflorineAn aporphine alkaloid that is (S)-corytuberine in which the nitrogen has been quaternised by an additional methyl group.(S)-magnoflorine
n-methylactinodaphnine(+)-Cassythicine
n-n-propylnorapomorphine(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol
R-(-)-actinodaphnineR-(-)-actinodaphnine
xylopineXylopine

Research

Studies (9,231)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19904,886 (52.93)18.7374
1990's1,907 (20.66)18.2507
2000's1,325 (14.35)29.6817
2010's914 (9.90)24.3611
2020's199 (2.16)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials295 (2.97%)5.53%
Reviews438 (4.41%)6.00%
Case Studies119 (1.20%)4.05%
Observational11 (0.11%)0.25%
Other9,062 (91.30%)84.16%