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diarylheptanoid

A family of plant metabolites with a common 1,7-diphenylheptane structural skeleton, carrying various substituents. They are mainly distributed in the roots, rhizomes and bark of Alpinia, Zingiber, Curcuma and Alnus species.

ChEBI ID: 78802

Members (25)

MemberDefinitionRole
(E)-1,7-Bis(4-hydroxyphenyl)hept-4-en-3-one(E)-1,7-Bis(4-hydroxyphenyl)hept-4-en-3-one
[3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(3,4-dimethoxyphenyl)methanone[3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(3,4-dimethoxyphenyl)methanone
1-(4-hydroxyphenyl)-7-phenyl-(6E)-hept-6-en-3-oneA diarylheptanoid that is hept-6-en-3-one substituted by a 4-hydroxyphenyl group at position 1 and a phenyl group at position 7 respectively. It has been isolated from the rhizomes of Curcuma kwangsiensis.1-(4-hydroxyphenyl)-7-phenyl-(6E)-hept-6-en-3-one
1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one(1E,4E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-oneA diarylheptanoid that is 1,4,6-heptatrien-3-one substituted by 4-hydroxypheny group at positions 1 and 7 respectively. It has been isolated from the rhizomes of Curcuma domestica and Etlingera elatior.1,7-bis (4-hydroxyphenyl)-1,4,6-heptatrien-3-one
1,7-bis(4-hydroxyphenyl)hepta-4E-6E-dien-3-oneA diarylheptanoid that is 4E-6E-dien-3-one substituted by 4-hydroxyphenyl group at positions 1 and 7. It has been isolated from the rhizomes of Curcuma kwangsiensis.1,7-bis(4-hydroxyphenyl)hepta-4E-6E-dien-3-one
3-(3-fluoro-4-methoxyphenyl)-5-phenyl-7-furo[3,2-g][1]benzopyranone3-(3-fluoro-4-methoxyphenyl)-5-phenyl-7-furo[3,2-g][1]benzopyranone
5-[(4-chlorophenyl)-oxomethyl]-4-hydroxy-6-[5-(2-nitrophenyl)-2-furanyl]-4-(trifluoromethyl)-1,3-diazinan-2-one5-[(4-chlorophenyl)-oxomethyl]-4-hydroxy-6-[5-(2-nitrophenyl)-2-furanyl]-4-(trifluoromethyl)-1,3-diazinan-2-one
5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenyl-3- heptanone5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenyl-3-heptanone
5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-(3-methyl-1-piperidinyl)-3-oxopropyl]-4-phenyl-1-benzopyran-2-one5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-(3-methyl-1-piperidinyl)-3-oxopropyl]-4-phenyl-1-benzopyran-2-one
8-[1-[4-(dimethylamino)phenyl]-3-(3-methyl-1-piperidinyl)propyl]-5,7-dimethoxy-4-phenyl-1-benzopyran-2-one8-[1-[4-(dimethylamino)phenyl]-3-(3-methyl-1-piperidinyl)propyl]-5,7-dimethoxy-4-phenyl-1-benzopyran-2-one
bisdemethoxycurcuminA beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups.bisdemethoxycurcumin
bromadioloneBromadiolone
curcuminA beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.curcumin
curcumin glucuronidecurcumin glucuronide
demethoxycurcuminA beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior.demethoxycurcumin
dichamanetinDichamanetin
gingerenone aGingerenone A
hexahydrocurcuminHexahydrocurcumin
hirsutanone(4E)-1,7-bis(3,4-dihydroxyphenyl)hept-4-en-3-one
myricanoneA cyclic ketone isolated from the bark of Morella species and has been shown to exhibit cytotoxic activity against cancer cells.Myricanone
oregoninOregonin
panduratin aPanduratin A
tetrahydrocurcuminA beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds.tetrahydrocurcumin
tetrahydroxycurcuminA beta-diketone that is curcumin in which the two methoxy groups have been replaced by hydroxy groups. It is a metabolite of curcumin.tetrahydroxycurcumin

Research

Studies (16,228)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199095 (0.59)18.7374
1990's334 (2.06)18.2507
2000's2,344 (14.44)29.6817
2010's8,802 (54.24)24.3611
2020's4,653 (28.67)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials622 (3.58%)5.53%
Reviews1,782 (10.27%)6.00%
Case Studies78 (0.45%)4.05%
Observational6 (0.03%)0.25%
Other14,868 (85.66%)84.16%