Page last updated: 2024-08-05 10:43:09
acetate ester
Any carboxylic ester where the carboxylic acid component is acetic acid.
ChEBI ID: 47622
Members (109)
| Member | Definition | Role |
|---|---|---|
| 1,9-dideoxyforskolin | A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin. | 1,9-dideoxyforskolin |
| 1'-acetoxychavicol acetate | An acetate ester that is chavicol acetate substituted by an acetoxy group at position 1'. | 1'-acetoxychavicol acetate |
| 11-cis-vaccenyl acetate | (Z)-octadec-11-enyl acetate | |
| 16-acetylgitoxin | A cardenolide glycoside that is the 16-acetate of gitoxin. | 16-O-acetylgitoxin |
| 2-phenylethyl acetate | The acetate ester of 2-phenylethanol. | phenethyl acetate |
| 3-mercaptohexyl acetate | An acetate ester obtained by formal O-acetylation of 3-mercaptohexanol. | 3-mercaptohexyl acetate |
| 4-methylumbelliferyl acetate | An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group. | 4-methylumbelliferyl acetate |
| 5-bromo-4-chloroindoxyl acetate | An acetate ester obtained by formal condensation of the carboxy group of acetic acid with the hydroxy group of 5-bromo-4-chloroindoxyl. | 5-bromo-4-chloro-3-indolyl acetate |
| 5-chloromethylfluorescein diacetate | 5-chloromethylfluorescein diacetate | |
| acequinocyl | An acetate ester consisting of 1,4-naphthoquinone bearing acetoxy and dodecyl substituents at positions 2 and 3 respectively. | acequinocyl |
| acetyl aleuritolic acid | A pentacyclic triterpenoid isolated from the leaves of Garcia parviflora. | acetyl aleuritolic acid |
| acetylspiramycin | A macrolide antibiotic produced by various Streptomyces species. | spiramycin II |
| acetylstrophanthidin | An acetate ester that is strophanidin acetylated at the 3beta-hydroxy group. | acetylstrophanthidin |
| amcinonide | amcinonide | |
| amyl acetate | An acetate ester of pentanol. | pentyl acetate |
| asperuloside | A iridoid monoterpenoid glycoside isolated from Galium verum. | asperuloside |
| ay 25545 | A C-glycosylated naphthoisochromene derivative obtained from Streptomyces ravidus; exhibits antibiotic and anticancer properties. | ravidomycin |
| azadirachtin | A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica). | azadirachtin A |
| azadiradione | A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by oxo groups at positions 3 and 16, an acetoxy group at position 7 and a furan-3-yl group at position 17. Isolated from Azadirachta indica, it exhibits antimycobacterial and anti-inflammatory activities. | azadiradione |
| azadirone | A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by an oxo group at position 3, an acetoxy group at position 7 and a furan-3-yl group at position 17. Isolated from Azadirachta indica, it exhibits antiplasmodial and antineoplastic activities. | azadirone |
| azaribine | A N-glycosyl-1,2,4-triazine that is 6-azauridine acetylated at positions 2', 3' and 5' on the sugar ring. It is a prodrug for 6-azauridine and is used for treatment of psoriasis. | azaribine |
| baccatin iii | A tetracyclic diterpenoid isolated from plant species of the genus Taxus. | baccatin III |
| benzyl acetate | The acetate ester of benzyl alcohol. | benzyl acetate |
| betamethasone acetate | betamethasone acetate | |
| bielschowskysin | A diterpenoid that is isolated from Pseudopterogorgia kallos and exhibits antimalarial and anticancer activity. | bielschowskysin |
| bigelovin | A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetoxy group at position 4. Isolated from Inula hupehensis, it exhibits antineoplastic activity. | bigelovin |
| bornyl acetate | (+)-bornyl acetate | |
| brl 42810 | 2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients. | famciclovir |
| bryostatin 1 | A member of the class of bryostatins that is (17E)-2-oxooxacyclohexacos-17-ene which is substituted by hydroxy groups at positions 4, 10, and 20; an acetoxy group at position 8; methyl groups at positions 9, 9, 18, and 19; 2-methoxy-2-oxoethylidene groups at positions 14 and 24; an (E,E)-octa-2,4-dienoyloxy group at position 21; and with oxygen bridges linking positions 6 to 10, 12 to 16, and 20 to 24. It is one of the most abundant member of the class of bryostatins. | bryostatin 1 |
| butyl acetate | The acetate ester of butanol. | butyl acetate |
| calcein am | An organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases. | calcein am |
| cerberin | A cardenolide glycoside that is the 2'-acetyl derivative of neriifolin. | cerberin |
| chloramphenicol 3-acetate | chloramphenicol 3-acetate | |
| cholesterol acetate | A cholesterol ester obtained by formal acylation of the hydroxy group of cholesterol by acetic acid. | cholesteryl acetate |
| cinnamyl acetate | trans-cinnamyl acetate | |
| cis-3-hexenyl acetate | An acetate ester that results from the formal condensation of acetic acid with (Z)-hex-3-en-1-ol. | (3Z)-hex-3-en-1-yl acetate |
| citronellyl acetate | A monoterpenoid that is the acetate ester of citronellol. It has been isolated from Citrus hystrix. | citronellol acetate |
| colforsin | A labdane diterpenoid isolated from the Indian Coleus plant. | forskolin |
| colforsin daropate | A carboxylic ester resuting from the formal condensation of the carboxy group of N,N-dimethyl-beta-alanine with the 6-hydroxy group of forskolin. It is an adenylate cyclase activator. | colforsin daropate |
| columbianetin acetate | An acetate ester obtained by formal acetylation of the tertiary hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. | columbianetin acetate |
| cyproterone acetate | A steroid ester resulting from the formal condensation of the carboxy group of acetic acid with the 17-hydroxy group of cyproterone. It is an antiandrogenic drug which has recently been recognized to promote the occurrence and growth of intracranial meningiomas. | cyproterone acetate |
| deltaline | deltaline | |
| deoxyaconitine | A diterpene alkaloid with formula C34H47NO10 that is isolated from several Aconitum species. | deoxyaconitine |
| diflorasone diacetate | The 17,21-diacetate derivative of diflorasone. It is used topically for its anti-inflammatory and antipruritic properties in the treatment of various skin disorders. | diflorasone diacetate |
| dilacor xr | A lactam that is 2,3-dihydro-1,5-benzothiazepin-4(5H)-one in which positions 2 and 3 are substituted by 4-methoxyphenyl and acetoxy, respectively, while the hydrogen attached to the nitrogen is substituted by a 2-(dimethylamino)ethyl group. | 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate |
| ecteinascidin 743 | A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer. | trabectedin |
| epoxyazadiradione | A limonoid that is azadiradione with an epoxy group across positions 14 and 15. Isolated from Azadirachta indica it exhibits insecticidal activitry against mosquitoes. | epoxyazadiradione |
| ergolide | A sesquiterpene lactone that is decahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetyloxy group at position 4. It has been isolated from the aerial parts of Inula hupehensis. | ergolide |
| eslicarbazepine acetate | The acetate ester, with S configuration, of licarbazepine. An anticonvulsant, it is approved for use in Europe and the United States as an adjunctive therapy for epilepsy. | eslicarbazepine acetate |
| ethyl acetate | The acetate ester formed between acetic acid and ethanol. | ethyl acetate |
| euonine | A sesquiterpene alkaloid that has been isolated from Tripterygium wilfordii and exhibits immunosuppressive and insecticidal properties. It was found to be identical with euonine, previously isolated from Euonymous sieboldiana. | wilformine |
| fludrocortisone acetate | An acetate ester resulting from the formal condensation of the primary hydroxy group of fludrocortisone with acetic acid. A synthetic corticosteroid, it has glucocorticoid actions about 10 times as potent as hydrocortisone, while its mineralocorticoid actions are over 100 times as potent. It is used in partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenal hyperplasia. | fludrocortisone acetate |
| fr 901464 | A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663. | FR901464 |
| gedunin | A pentacyclic triterpenoid natural product found particularly in Azadirachta indica and Cedrela odorata. | gedunin |
| geranyl acetate | A monoterpenoid that is the acetate ester derivative of geraniol. | geranyl acetate |
| grayanotoxin i | A tetracyclic diterpenoid that is grayanotoxane in which the pro-R hydrogen at position 14 is substituted by an acetoxy group and in which the 3beta-, 5-, 6beta-, 10-, and 16- positions are substituted by hydroxy groups. | grayanotoxin I |
| gs 4071 | A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). An antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza. | oseltamivir acid |
| helvolic acid | A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24. | helvolic acid |
| HT-2 toxin | A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin. | HT-2 toxin |
| hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester | An organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation. | hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester |
| isoamyl acetate | The acetate ester of isoamylol. | isoamyl acetate |
| isobutyl acetate | The acetate ester of isobutanol. | isobutyl acetate |
| josamycin | A macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus. | josamycin |
| linalyl acetate | A monoterpenoid that is the acetate ester of linalool. It forms a principal component of the essential oils from bergamot and lavender. | 3,7-dimethylocta-1,6-dien-3-yl acetate |
| medroxyprogesterone acetate | An acetate ester resulting from the formal condensation of the 17alpha-hydroxy group of medroxyprogesterone with the carboxy group of acetic acid. A widely used progestin in menopausal hormone therapy and in progestogen-only birth control. | medroxyprogesterone acetate |
| megestrol acetate | A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. | megestrol acetate |
| methacholine | A quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group. Parasympathomimetic bronchoconstrictor drug used in clinical diagnosis. | methacholine |
| methyl acetate | An acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 degreeC) colourless, flammable liquid, it is used as a solvent for many resins and oils. | methyl acetate |
| methylprednisolone acetate | An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid. | methylprednisolone acetate |
| metipranolol | 3-(Propan-2-ylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by a 4-acetoxy-2,3,5-trimethylphenoxy group. A non-cardioselective beta-blocker, it is used to lower intra-ocular pressure in the management of open-angle glaucoma. | metipranolol |
| nimbin | A limonoid found in Azadirachta indica. | nimbin |
| nisone | cortancyl | |
| norethindrone acetate | A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester. | norethisterone acetate |
| octyl acetate | The acetate ester of octan-1-ol. | octyl acetate |
| pancuronium | A steroid ester in which a 5alpha-androstane skeleton is C-3alpha- and C-17beta-disubstituted with acetoxy groups and 2beta- and 16beta-disubstituted with 1-methylpiperidinium-1-yl groups. It is a non-depolarizing curare-mimetic muscle relaxant. | pancuronium |
| pedilstatin | A phorbol ester that is 4-deoxyphorbol in which the hydroxy groups at positions 12 and 13 have been replaced by octa-2,4-dienoyloxy and acetyloxy groups respectively. | pedilstatin |
| phentin acetate | An organotin compound that is the O-acetyl derivative of triphenyltin hydroxide. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans. | fentin acetate |
| pn 401 | An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. | uridine triacetate |
| poly-o-acetylserine | An acetyl-L-serine where the acetyl group is attached to the side-chain oxygen. It is an intermediate in the biosynthesis of the amino acid cysteine in bacteria. | O-acetyl-L-serine zwitterion; O-acetyl-L-serine |
| prasugrel | A member of the class of thienopyridines that is 2-acetoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the amino hydrogen is replaced by a 2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl group. | 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate |
| propyl acetate | An acetate ester obtained by the formal condensation of acetic acid with propanol. | propyl acetate |
| px-866 | An organic heterotetracyclic compound that is obtained from wortmanin via aminolysis of its furan ring by diallyl amine. | PX-866 |
| retinol acetate | retinyl acetate | |
| rifamycin b | rifamycin B | |
| rifamycin sv | A member of the class of rifamycins that exhibits antibiotic and antitubercular properties. | rifamycin SV |
| rifaximin | A semisynthetic member of the class of rifamycins and non-systemic gastrointestinal site-specific broad spectrum antibiotic. Used in the treatment of traveller's diarrhoea, hepatic encephalopathy and irritable bowel syndrome. | rifaximin |
| rocuronium | A 5alpha-androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents. | rocuronium |
| rosiglitazone | A coumarin substituted by a methyl group at position 4 and by acetyloxy groups at positions 7 and 8. It exhibits strong antioxidant and radical scavenging properties. | 7,8-diacetoxy-4-methylcoumarin |
| salannin | A limonoid with insecticidal activity isolated from Azadirachta indica. | salannin |
| scalaradial | A scalarane sesterterpenoid with formula C27H40O4. It is a natural product found in the marine sponges Spongia officinalis and Cacospongia mollior, and exhibits anti-inflammatory activity. | scalaradial |
| sm 1 peptide | An ergot alkaloid produced by the fungus Aspergillus fumigatus that is ergoline which is substituted by a 2-methylbut-3-en-2-yl group at position 2, methyl groups at the 6 and 8beta positions, and by an acetoxy group at the 9beta position. | fumigaclavine C |
| squalestatin 1 | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid A |
| t-2 toxin | A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. | T-2 toxin |
| taxusin | A taxane diterpenoid that is taxa-4(20),11-diene in which the 5alpha, 9alpha, 10beta and 13alpha hydrogens have been replaced by acetoxy groups. It is a prominent secondary metabolite of yew heartwood. | taxusin |
| tetradecanoylphorbol acetate | A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types. | phorbol 13-acetate 12-myristate |
| thiopropazate | A phenothiazine derivative in which 10H-phenothiazine has a chloro subsitituent at the 2-position and a 3-[4-(2-acetoxyethyl)piperazin-1-yl]propyl group at N-10. | thiopropazate |
| troleandomycin | A semi-synthetic macrolide antibiotic obtained by acetylation of the three free hydroxy groups of oleandomycin. Troleandomycin is only found in individuals that have taken the drug. | troleandomycin |
| ulipristal acetate | A 20-oxo steroid obtained by acetylation of the 17-hydroxy group of (11beta,17alpha)-17-acetyl-11-[4-(dimethylamino)phenyl]-3-oxoestra-4,9-dien-17-ol (ulipristal). A selective progesterone receptor modulator, which is employed as an emergency contraceptive. | ulipristal acetate |
| vecuronium | A 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidino- and 16beta-N-methylpiperidinium substituents. | vecuronium |
| versiconal hemiacetal acetate | An anthrafuran that is 2,3-dihydroanthra[2,3-b]furan-5,10-dione substituted at positions 2, 4, 6 and 8 by hydroxy groups and at position 3 by a 2-acetoxyethyl group. An intermediate in the biosynthesis of aflatoxin. | versiconal hemiacetal acetate |
| vincaleukoblastine | vincaleukoblastine | |
| vincristine | A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. | vincristine |
| vinflunine | An organic heteropentacyclic compound and an organic heterotetracyclic compound that is vinorelbine in which the tetrahydropyridine moiety of the heterotetracyclic part of the molecule has been redced to the corresponding piperidine, and in which the ethyl group attached to this ring has been replaced by a 1,1-difluoroethyl group. | vinflunine |
| vinorelbine | A vinca alkaloid with a norvinblastine skeleton. | vinorelbine |
| vinyl acetate | vinyl acetate | |
| wilforgine | A dihydroagarofuran sesquiterpenoid and pyridine alkaloid with formula C41H47NO19 originally isolated from the roots of Tripterygium wilfordii. | wilforgine |
| wortmannin | wortmannin | |
| yunaconitine | A diterpene alkaloid with formula C35H49NO11 that is isolated from several Aconitum species. | yunaconitine |
| zaragozic acid c | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid C |
Research
Studies (67,767)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14,405 (21.26) | 18.7374 |
| 1990's | 24,382 (35.98) | 18.2507 |
| 2000's | 16,583 (24.47) | 29.6817 |
| 2010's | 10,261 (15.14) | 24.3611 |
| 2020's | 2,136 (3.15) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 3,926 (5.39%) | 5.53% |
| Reviews | 2,205 (3.03%) | 6.00% |
| Case Studies | 1,885 (2.59%) | 4.05% |
| Observational | 149 (0.20%) | 0.25% |
| Other | 64,628 (88.78%) | 84.16% |