Anemia, Megaloblastic

A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.

Synonym
Anemia, Megaloblastic

Excerpt	Reference
"Most, but not all, megaloblastic anemia is produced by "ineffective erythropoiesis" in the bone marrow due to either folic acid or vitamin B12 deficiency."	( Castle, WB, 1978)
"Macrocytic megaloblastic anemia is the most typical but the latest sign of a cobalamin (vitamin B12) and/or folic acid deficiency or of a congenital abnormality of cobalamin and folate metabolism."	( Zittoun, J, 1993)
"Megaloblastic anemias are basically caused by vitamin B(12) and/or folic acid deficiency."	( Kvezereli-Kopadze, AN; Kvezereli-Kopadze, MA; Mtvarelidze, ZG, 2009)
"Thiamine-responsive megaloblastic anemia is a rare autosomal recessive disorder whose main symptoms are anemia, diabetes mellitus, and sensorineural deafness."	( Azzalli, M; Borgna-Pignatti, C; Pedretti, S, 2009)
"Megaloblastic anemias are a subgroup of macrocytic anemias, in which distinctive morphologic abnormalities occur in red cell precursors in bone marrow, namely megaloblastic erythropoiesis."	( Ferreira, KB; Fonseca, FP; Neto, NC; Pinto, Ddos S; Pontes, FS; Pontes, HA; Vallinoto, GM, 2009)
"Megaloblastic anemia is not uncommon in developing countries."	( Byotra, SP; Hussain, S; Kakar, A; Masoodi, I; Sachdev, MK, 2011)
"Megaloblastic anemias are basically caused by vit."	( Kvezereli-Kopadze, M; Mtvarelidze, Z, 2019)
"Megaloblastic anemia is due to disruptions in DNA synthesis during hematopoiesis and can be a result of an inherited or drug-induced disorder or a consequence of folate or cobalamin deficiency."	( Cora, M, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	710 (62.06)	23.3326
1990's	122 (10.66)	12.5806
2000's	131 (11.45)	18.1394
2010's	125 (10.93)	28.8240
2020's	56 (4.90)	9.53

Drug	Relationship Strength	Studies	Trials
aminolevulinic acid	low	1	0
adenine	low	1	0
benzene	low	1	0
formic acid	low	2	0
choline	low	1	0
salicylic acid	low	1	0
methylmalonic acid	low	28	0
cytosine	low	1	0
lactic acid	low	3	0
glycine	low	3	0
histamine	low	1	0
nitrous oxide	medium	24	1
orotic acid	low	10	0
purine	low	4	0
pyridoxine	low	3	0
thiamine	low	92	0
thymine	low	1	0
uracil	low	6	0
uric acid	low	3	0
phenytoin	low	17	0
amobarbital	low	1	0
azathioprine	low	7	0
benphothiamine	low	1	0
busulfan	low	2	0
caffeine	low	1	0
chloroquine	low	3	0
chlorpromazine	low	1	0
dapsone	low	3	0
deferoxamine	low	1	0
valproic acid	low	1	0
erythrosine	low	1	0
fluorouracil	low	5	0
glutethimide	low	1	0
halothane	low	1	0
hydroxyurea	low	9	0
isoniazid	low	1	0
lansoprazole	low	1	0
mesalamine	low	1	0
metformin	low	4	0
metronidazole	low	1	0
ethylmaleimide	low	2	0
niclosamide	low	2	0
omeprazole	low	1	0
oxonic acid	medium	1	1
oxyphenbutazone	low	2	0
aminosalicylic acid	low	2	0
pentamidine	low	1	0
phenacetin	low	1	0
phenobarbital	low	16	0
phenylbutazone	low	2	0
pipobroman	low	1	0
piracetam	low	1	0
primidone	low	20	0
probenecid	low	1	0
pyrimethamine	low	19	0
risperidone	low	1	0
secobarbital	low	1	0
sulfamethoxazole	low	14	0
sulfasalazine	low	10	0
tegafur	medium	1	1
triamterene	low	7	0
trimethadione	low	1	0
trimethoprim	low	18	0
prednisolone	low	5	0
thymidine	low	24	0
thyroxine	low	1	0
lynestrenol	low	1	0
norethandrolone	low	1	0
prednisone	low	1	0
azauridine	low	1	0
penicillin g	low	3	0
biguanides	low	1	0
serine	low	4	0
chloramphenicol	low	9	0
aspartic acid	low	1	0
glutamine	low	1	0
ethinyl estradiol	low	3	0
chlordan	low	1	0
adenosine diphosphate	low	1	0
uridine	low	5	0
uridine monophosphate	low	1	0
bromodeoxyuridine	low	1	0
edetic acid	low	1	0
tyrosine	low	2	0
methionine	low	25	0
colchicine	low	2	0
barbituric acid	low	5	0
norethindrone	low	1	0
ampicillin	low	1	0
cytarabine	low	1	0
histidine	low	8	0
mestranol	low	3	0
phensuximide	low	1	0
phosphoribosyl pyrophosphate	low	1	0
1,3-butadiene	low	2	0
pyrroles	low	1	0
ergotamine	low	1	0
mephobarbital	low	1	0
framycetin	low	2	0
diphenhydramine hydrochloride	low	1	0
thiamine pyrophosphate	low	7	0
quinazolines	low	1	0
pyrimidine	low	2	0
ethynodiol diacetate	low	1	0
nitroblue tetrazolium	low	1	0
hydrazine	low	1	0
thymidine monophosphate	low	3	0
nandrolone	low	1	0
hydantoins	low	18	0
homocystine	low	1	0
malondialdehyde	low	1	0
eosine yellowish-(ys)	low	1	0
4-chloromercuribenzenesulfonate	low	1	0
congo red	low	1	0
erythromycin	low	1	0
ethylnitrosourea	low	1	0
norgestrienone	low	1	0
deoxyuridine	medium	39	1
durapatite	low	1	0
sodium hydroxide	low	1	0
d-alpha tocopherol	low	1	0
amiloride	low	1	0
sulfadoxine	low	1	0
carbenicillin	low	1	0
technetium	low	1	0
gold	low	1	0
ferrous sulfate	low	2	0
ammonium ferric sulfate	low	1	0
trolamine salicylate	low	2	0
urobilinogen	low	1	0
phytanic acid	low	1	0
danazol	low	1	0
phenyl acetate	low	1	0
transferrin	low	13	0
glutamic acid	low	1	0
amoxicillin	low	1	0
zidovudine	low	1	0
methyldopa	low	3	0
metsulfuron methyl	low	1	0
adenosine	low	1	0
trimethoprim, sulfadoxine drug combination	low	1	0
3-aminoisobutyric acid	low	1	0
thymidine 5'-triphosphate	low	1	0
5-methylcytosine	low	1	0
2'-deoxycytidine 5'-triphosphate	low	1	0
sertraline	low	1	0
leupeptin	low	1	0
clarithromycin	low	1	0
homocysteine	low	31	0
orotidine	low	1	0
vitamin b 6	low	1	0
artesunic acid	low	1	0
entonox	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
methotrexate	low	30	0
xylose	low	1	0
aminopterin	low	2	0
biotin	low	1	0
angiotensin ii	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	4	0
leupeptins	low	1	0
s-adenosylhomocysteine	low	3	0
5'-methylthioadenosine	low	1	0
formiminoglutamic acid	low	8	0
puromycin	low	1	0
retinol	low	1	0
tacrolimus	low	1	0
mycophenolic acid	low	1	0
tenofovir	low	1	0
riboflavin	low	2	0
isomethyleugenol	low	7	0
mercaptopurine	low	1	0
urocanic acid	low	2	0
lithium	low	1	0
quinine	low	1	0
6-thioguanylic acid	low	1	0
myelin basic protein	low	1	0
bilirubin	low	2	0
vitamin k semiquinone radical	low	1	0
lead	low	1	0
diamide	low	1	0
arsenic	low	2	0
sulfur	low	1	0
cysteine	low	1	0
phosphorus	low	2	0
proguanil	low	3	0
factor iii, vitamin b 12	low	1	0
nitrofurantoin	low	6	0
pentagastrin	low	2	0
mocetinostat	low	4	0
ribose	low	1	0
losartan potassium	low	12	0
sepharose	low	1	0
acid phosphatase	low	1	0
cholecystokinin	low	1	0
gastrins	low	5	0
oligonucleotides	low	1	0
ristocetin	low	1	0
cellulose	low	1	0
s-adenosylmethionine	low	4	0
intrinsic factor	low	50	0
hydroxocobalamin	low	25	0
heme	low	2	0
ascorbic acid	low	16	0
tetracycline	medium	9	1
chlortetracycline	low	1	0
oxytetracycline, anhydrous	low	1	0
salicylates	low	1	0
s 1 (combination)	medium	1	1
epidermal growth factor	low	1	0
aquacobalamin	low	1	0
cyclin d1	low	1	0
cobamamide	low	3	0
epoetin alfa	low	1	0
vitamin b 12	medium	515	5
norgestrel	low	2	0
technetium tc 99m medronate	low	1	0
thromboplastin	low	1	0
exudates	low	1	0
acyclovir	low	1	0
levoleucovorin	low	29	0
sapropterin	low	1	0
folic acid	medium	413	4
olanzapine	low	1	0
bl 4162a	low	1	0
5,6,7,8-tetrahydrofolic acid	low	2	0
amg531	low	1	0
5-methyltetrahydrofolate	low	10	0
eye	low	1	0
antimony sodium gluconate	low	1	0

Protein Targets (1,653)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Reverse transcriptase/RNaseH	0	3	5	15
Canalicular multispecific organic anion transporter 1	0	3	0	4
Protein arginine N-methyltransferase 5	0	2	1	3
Indolethylamine N-methyltransferase	0	2	0	2
Adenosine receptor A3	0	9	2	12
Catechol O-methyltransferase	0	1	0	1
Adenosine receptor A1	0	7	1	12
Adenosine receptor A2a	0	6	3	12
Adenosine receptor A2b	0	2	1	6
Adenosine receptor A2a	0	4	1	10
Fatty acid synthase	0	7	0	7
S-methyl-5'-thioadenosine phosphorylase	0	0	0	1
Methylosome protein 50	0	1	1	2
Spermidine synthase	0	1	0	1
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	3
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	19	0	0	19
Chain B, HADH2 protein	19	0	0	19
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Chain A, Ferritin light chain	11	0	0	11
Thymidine kinase	0	2	0	3
thioredoxin reductase	34	0	0	34
phosphopantetheinyl transferase	27	0	0	27
GLS protein	19	0	0	19
TDP1 protein	60	0	0	60
Smad3	13	0	0	13
thyroid stimulating hormone receptor	24	0	0	24
EWS/FLI fusion protein	27	0	0	27
arylsulfatase A	17	0	0	17
euchromatic histone-lysine N-methyltransferase 2	52	0	0	52
activating transcription factor 6	21	0	0	21
Histone H2A.x	28	0	0	28
Bloom syndrome protein isoform 1	16	0	0	16
hemoglobin subunit beta	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
ubiquitin carboxyl-terminal hydrolase 2 isoform a	10	0	0	10
lamin isoform A-delta10	42	0	0	42
Solute carrier family 22 member 1	0	12	0	16
ATP-binding cassette sub-family C member 3	0	42	0	42
Multidrug resistance-associated protein 4	0	42	0	44
Solute carrier family 22 member 6	0	6	0	8
Bile salt export pump	0	13	0	13
Bile salt export pump	0	63	0	63
Purine nucleoside phosphorylase	0	2	0	2
Thymidine kinase, cytosolic	0	6	0	12
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	18	0	18
Cytochrome P450 2J2	0	14	0	14
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	4	0	9
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	6	0	11
Canalicular multispecific organic anion transporter 1	0	40	0	40
Thymidine kinase	0	2	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	29	0	0	29
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	47	0	0	47
AR protein	68	0	0	68
nuclear receptor subfamily 1, group I, member 3	46	0	0	46
cytochrome P450 family 3 subfamily A polypeptide 4	40	0	0	40
glucocorticoid receptor [Homo sapiens]	49	0	0	49
estrogen-related nuclear receptor alpha	61	0	0	61
pregnane X nuclear receptor	43	0	0	43
estrogen nuclear receptor alpha	80	0	0	80
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	29	0	0	29
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
heat shock protein beta-1	21	0	0	21
importin subunit beta-1 isoform 1	10	0	0	10
snurportin-1	10	0	0	10
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	7	0	0	7
Voltage-dependent calcium channel gamma-2 subunit	30	0	0	30
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	1	4
Glutamate receptor 2	30	3	1	34
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	13	0	0	13
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	18	0	0	18
Ataxin-2	24	0	0	24
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	19	0	0	19
retinoid X nuclear receptor alpha	40	0	0	40
NPYLR7B	0	0	2	2
IDH1	19	0	0	19
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	11	0	0	11
flap endonuclease 1	13	0	0	13
nuclear receptor ROR-gamma isoform 1	18	0	0	18
peripheral myelin protein 22	28	0	0	28
survival motor neuron protein isoform d	20	0	0	20
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	4	0	4
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	4	0	4
Rap guanine nucleotide exchange factor 3	12	0	0	12
Epidermal growth factor receptor	0	6	0	6
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	1	0	2
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	1	0	2
Inosine-5'-monophosphate dehydrogenase 2	0	3	0	3
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	3
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	2	2
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	3	9
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	4	0	4
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	3	1	4
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	4	0	4
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	8	2	10
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	6	1	7
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	8	0	0	8
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Luciferase	18	0	0	18
acetylcholinesterase	24	0	0	24
hypoxia-inducible factor 1 alpha subunit	15	0	0	15
estrogen receptor 2 (ER beta)	29	0	0	29
progesterone receptor	34	0	0	34
retinoic acid nuclear receptor alpha variant 1	49	0	0	49
farnesoid X nuclear receptor	34	0	0	34
G	25	0	0	25
cytochrome P450 2D6	24	0	0	24
peroxisome proliferator-activated receptor delta	28	0	0	28
peroxisome proliferator activated receptor gamma	36	0	0	36
vitamin D (1,25- dihydroxyvitamin D3) receptor	36	0	0	36
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	32	0	0	32
nuclear factor erythroid 2-related factor 2 isoform 1	51	0	0	51
Solute carrier organic anion transporter family member 2B1	0	3	0	4
Interferon beta	33	0	0	33
HLA class I histocompatibility antigen, B alpha chain	25	0	0	25
Replicase polyprotein 1ab	0	6	2	8
Replicase polyprotein 1ab	0	7	3	10
Thrombopoietin receptor	0	0	1	1
Potassium voltage-gated channel subfamily H member 2	0	22	0	22
Sodium channel protein type 5 subunit alpha	0	6	0	6
Inositol hexakisphosphate kinase 1	25	0	0	25
Solute carrier organic anion transporter family member 1B3	0	6	0	9
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	10
cytochrome P450 2C9, partial	25	0	0	25
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	24	0	0	24
acid sphingomyelinase	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	38	0	0	38
glucocerebrosidase	8	0	0	8
alpha-galactosidase	6	0	0	6
cytochrome P450 2D6 isoform 1	10	0	0	10
lysosomal alpha-glucosidase preproprotein	8	0	0	8
cytochrome P450 2C19 precursor	9	0	0	9
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	19	0	0	19
thyroid hormone receptor beta isoform 2	48	0	0	48
huntingtin isoform 2	4	0	0	4
geminin	60	0	0	60
Membrane primary amine oxidase	0	1	0	1
Prothrombin	0	1	1	2
Coagulation factor X	0	2	0	2
Plasminogen	0	3	0	3
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	2	0	2
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	2	0	6
Vitamin K-dependent protein C	0	1	0	1
Cellular tumor antigen p53	47	0	0	47
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	3	0	3
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	4
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	6	0	6
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	7	0	11
Solute carrier family 22 member 2	0	7	0	9
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Chain A, Beta-lactamase	19	0	0	19
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 2	0	3	1	4
Glutamate receptor 3	0	2	1	3
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Solute carrier family 15 member 1	0	6	0	6
Glutamate receptor 4	0	3	1	4
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 2	0	4	0	4
SMAD family member 2	17	0	0	17
SMAD family member 3	17	0	0	17
Dihydrofolate reductase	0	9	0	11
Dihydrofolate reductase	0	5	0	7
Dihydrofolate reductase	0	5	0	7
5-hydroxytryptamine receptor 2C	0	8	0	10
Dihydrofolate reductase	0	7	4	12
Folylpolyglutamate synthase, mitochondrial	0	2	0	6
Solute carrier organic anion transporter family member 1A3	0	2	0	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	6
Microtubule-associated protein tau	24	0	0	24
thioredoxin glutathione reductase	11	0	0	11
microphthalmia-associated transcription factor isoform 9	0	3	0	3
Carbonic anhydrase 1	0	10	0	17
Carbonic anhydrase 2	0	11	2	22
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
apical membrane antigen 1, AMA1	13	0	0	13
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	23	0	0	23
urokinase-type plasminogen activator precursor	16	0	0	16
plasminogen precursor	16	0	0	16
urokinase plasminogen activator surface receptor precursor	16	0	0	16
DNA polymerase kappa isoform 1	15	0	0	15
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	1	0	3
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	7	0	0	7
Beta-lactamase	0	0	0	2
GLI family zinc finger 3	52	0	0	52
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
chromobox protein homolog 1	33	0	0	33
DNA polymerase beta	8	0	0	8
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	1
Spike glycoprotein	22	3	2	27
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	1	1	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	3
60 kDa chaperonin	0	6	0	6
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	6	0	6
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	1	0	3
ATP-dependent phosphofructokinase	20	0	0	20
histone acetyltransferase KAT2A isoform 1	20	0	0	20
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	18	0	0	18
Polyphenol oxidase 2	0	4	0	6
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	15	1	16
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	24	0	0	24
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	4
Glutamate receptor ionotropic, NMDA 1	0	7	2	12
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	7	2	12
Glutamate receptor ionotropic, NMDA 2B	0	7	2	12
Glutamate receptor ionotropic, NMDA 2C	0	7	2	12
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	6
Glutamate receptor ionotropic, NMDA 2D	0	7	2	12
Glutamate receptor ionotropic, NMDA 3B	0	7	2	12
Carbonic anhydrase 4	0	0	0	3
Glutamate receptor ionotropic, NMDA 3A	0	7	2	12
interleukin 8	13	0	0	13
ATAD5 protein, partial	19	0	0	19
Fumarate hydratase	14	0	0	14
polyprotein	14	0	0	14
P53	1	0	0	1
aryl hydrocarbon receptor	23	0	0	23
thyroid stimulating hormone receptor	25	0	0	25
peripheral myelin protein 22 isoform 1	15	0	0	15
cellular tumor antigen p53 isoform a	13	0	0	13
cytochrome P450 3A4 isoform 1	26	0	0	26
M-phase phosphoprotein 8	11	0	0	11
muscleblind-like protein 1 isoform 1	11	0	0	11
muscarinic acetylcholine receptor M1	15	0	0	15
Gamma-aminobutyric acid receptor subunit pi	26	1	0	27
Gamma-aminobutyric acid receptor subunit beta-1	26	1	0	27
Gamma-aminobutyric acid receptor subunit delta	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-2	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-5	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-1	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-2	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-4	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-6	26	1	0	27
Nuclear receptor ROR-gamma	11	0	0	11
Gamma-aminobutyric acid receptor subunit alpha-1	26	1	0	27
Gamma-aminobutyric acid receptor subunit beta-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit beta-2	26	1	0	27
GABA theta subunit	26	1	0	27
Gamma-aminobutyric acid receptor subunit epsilon	26	1	0	27
Protein-arginine deiminase type-4	0	8	0	8
glp-1 receptor, partial	12	0	0	12
Skn7p	0	0	0	2
nonstructural protein 1	8	0	0	8
67.9K protein	16	0	0	16
Janus kinase 2 (a protein tyrosine kinase)	0	2	0	2
Orotidine 5'-phosphate decarboxylase	0	2	0	2
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Integrin beta-3	9	0	1	10
Integrin alpha-IIb	9	0	1	10
Alpha-synuclein	6	2	0	8
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
pregnane X receptor	15	0	0	15
Endolysin	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	12	0	0	12
USP1 protein, partial	27	0	0	27
vitamin D3 receptor isoform VDRA	21	0	0	21
caspase-1 isoform alpha precursor	6	0	0	6
Caspase-7	6	0	0	6
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
PPM1D protein	7	0	0	7
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	10	0	0	10
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine phosphorylase	0	0	0	3
Thymidylate kinase	0	2	0	3
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	4	0	5
15-lipoxygenase, partial	9	0	0	9
Matrix metalloproteinase-9	0	2	0	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
thyroid hormone receptor beta isoform a	19	0	0	19
Potassium channel subfamily K member 2	0	3	1	4
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Acetylcholinesterase	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	3	0	3
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	2
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	2	0	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	3
streptokinase A precursor	0	0	6	6
30S ribosomal protein S6	0	5	1	7
30S ribosomal protein S7	0	5	1	7
50S ribosomal protein L15	0	5	1	7
Cytochrome P450 3A4	0	18	0	19
50S ribosomal protein L10	0	5	1	7
50S ribosomal protein L11	0	5	1	7
50S ribosomal protein L7/L12	0	5	1	7
50S ribosomal protein L19	0	5	1	7
50S ribosomal protein L1	0	5	1	7
50S ribosomal protein L20	0	5	1	7
50S ribosomal protein L27	0	5	1	7
50S ribosomal protein L28	0	5	1	7
50S ribosomal protein L29	0	5	1	7
50S ribosomal protein L31	0	5	1	7
50S ribosomal protein L31 type B	0	5	1	7
50S ribosomal protein L32	0	5	1	7
50S ribosomal protein L33	0	5	1	7
50S ribosomal protein L34	0	5	1	7
50S ribosomal protein L35	0	5	1	7
50S ribosomal protein L36	0	5	1	7
30S ribosomal protein S10	0	5	1	7
30S ribosomal protein S11	0	5	1	7
30S ribosomal protein S12	0	5	1	7
30S ribosomal protein S13	0	5	1	7
30S ribosomal protein S16	0	5	1	7
30S ribosomal protein S18	0	5	1	7
30S ribosomal protein S19	0	5	1	7
30S ribosomal protein S20	0	5	1	7
30S ribosomal protein S2	0	5	1	7
30S ribosomal protein S3	0	5	1	7
30S ribosomal protein S4	0	5	1	7
30S ribosomal protein S5	0	5	1	7
30S ribosomal protein S8	0	5	1	7
30S ribosomal protein S9	0	5	1	7
50S ribosomal protein L13	0	5	1	7
50S ribosomal protein L14	0	5	1	7
50S ribosomal protein L16	0	5	1	7
50S ribosomal protein L23	0	5	1	7
30S ribosomal protein S15	0	5	1	7
50S ribosomal protein L17	0	5	1	7
50S ribosomal protein L21	0	5	1	7
50S ribosomal protein L30	0	5	1	7
50S ribosomal protein L6	0	5	1	7
30S ribosomal protein S14	0	5	1	7
30S ribosomal protein S17	0	5	1	7
30S ribosomal protein S1	0	5	1	7
50S ribosomal protein L18	0	5	1	7
50S ribosomal protein L2	0	5	1	7
50S ribosomal protein L3	0	5	1	7
50S ribosomal protein L24	0	5	1	7
50S ribosomal protein L4	0	5	1	7
50S ribosomal protein L22	0	5	1	7
50S ribosomal protein L5	0	5	1	7
30S ribosomal protein S21	0	5	1	7
50S ribosomal protein L25	0	5	1	7
50S ribosomal protein L36 2	0	5	1	7
Methionine--tRNA ligase, mitochondrial	0	0	1	1
caspase 7, apoptosis-related cysteine protease	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
caspase-3	7	0	0	7
Caspase-7	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
caspase-3	4	0	0	4
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
Androgen receptor	0	16	0	16
Peroxisome proliferator-activated receptor alpha	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	3	0	3
Spike glycoprotein	0	3	2	5
Replicase polyprotein 1ab	0	4	3	7
glucose-6-phosphate 1-dehydrogenase isoform b	0	3	0	3
Transmembrane protease serine 2	0	3	2	5
Dihydrofolate reductase	0	5	0	5
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	3	3
Amyloid-beta precursor protein	2	5	0	7
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	4	2	6
Muscarinic acetylcholine receptor M2	0	11	0	11
Muscarinic acetylcholine receptor M4	0	11	0	11
Muscarinic acetylcholine receptor M5	0	12	0	12
Alpha-2A adrenergic receptor	0	17	0	17
Replicase polyprotein 1a	0	3	2	5
Replicase polyprotein 1ab	0	3	2	5
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	9	1	10
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	15	0	15
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	10	0	10
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	8	0	8
Angiotensin-converting enzyme 2	0	3	2	5
Cysteine proteinase falcipain 2a	0	2	0	2
Cysteine proteinase falcipain 2a	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
NFKB1 protein, partial	5	0	0	5
Thrombopoietin	6	0	0	6
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	3	0	3
D(1A) dopamine receptor	5	0	0	5
histone deacetylase 9 isoform 3	6	0	0	6
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
ras-related protein Rab-9A	7	0	0	7
Proteasome subunit alpha type-7	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	14	0	14
Albumin	0	2	4	6
Albumin	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	4	1	6
Tyrosine-protein kinase Fyn	0	3	0	3
Aldo-keto reductase family 1 member B1	0	15	0	15
ATP-dependent translocase ABCB1	0	13	1	20
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
5-hydroxytryptamine receptor 1A	0	5	3	8
Muscarinic acetylcholine receptor M5	0	3	0	3
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Cytochrome P450 2D6	0	10	1	11
Muscarinic acetylcholine receptor M2	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Angiotensin-converting enzyme	0	10	0	10
D(2) dopamine receptor	0	10	1	14
5-hydroxytryptamine receptor 2A	0	10	0	11
Alpha-1B adrenergic receptor	0	11	0	11
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	7	0	7
D(3) dopamine receptor	0	7	0	7
5-hydroxytryptamine receptor 1A	0	11	0	11
Alpha-2B adrenergic receptor	0	5	0	5
D(2) dopamine receptor	0	3	0	3
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	12	0	14
D(4) dopamine receptor	0	7	1	11
D(1B) dopamine receptor	0	3	0	5
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	5	0	5
UDP-glucuronosyltransferase 1A4	0	2	0	6
Alpha-2A adrenergic receptor	0	5	0	5
Alpha-1D adrenergic receptor	0	7	0	7
Sodium-dependent noradrenaline transporter	0	15	1	16
Sodium-dependent dopamine transporter	0	6	0	6
Histamine H2 receptor	0	7	2	9
Alpha-1D adrenergic receptor	0	10	0	10
D(1B) dopamine receptor	0	5	0	5
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	16	0	16
5-hydroxytryptamine receptor 2C	0	14	0	14
5-hydroxytryptamine receptor 1B	0	7	0	7
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	6	0	6
5-hydroxytryptamine receptor 2B	0	8	0	8
Histamine H1 receptor	0	4	3	7
Sodium-dependent serotonin transporter	0	17	1	18
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	4	0	4
Histamine H1 receptor	0	10	3	13
D(3) dopamine receptor	0	14	1	18
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	4
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
5-hydroxytryptamine receptor 2B	0	12	0	12
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	11	0	11
Histamine H2 receptor	13	0	1	15
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	6	1	0	7
5-hydroxytryptamine receptor 6	0	9	0	9
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	9	0	10
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Sodium-dependent dopamine transporter	0	10	1	11
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	9	0	9
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	3	2	5
Sodium channel protein type 10 subunit alpha	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	5	0	8
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	4	1	0	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	4	1	0	5
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
endonuclease IV	10	0	0	10
PAX8	0	0	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	10	0	0	10
steroidogenic factor 1	0	1	0	1
neuropeptide S receptor isoform A	4	0	0	4
Solute carrier family 22 member 3	0	3	0	4
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
B2 bradykinin receptor	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Chymotrypsinogen A	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-galactosidase	0	1	0	2
Choline O-acetyltransferase	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
PH domain leucine-rich repeat-containing protein phosphatase 2	0	1	0	1
Chymotrypsin-C	0	1	0	1
dopamine D1 receptor	4	0	0	4
Glucocorticoid receptor	0	12	2	19
Sex hormone-binding globulin	0	0	5	5
Glycine receptor subunit alpha-1	0	12	0	12
Corticosteroid-binding globulin	0	3	0	3
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	7	0	7
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	4	0	6
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	2	0	3
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
Estrogen receptor	0	10	1	11
Beta-3 adrenergic receptor	0	2	0	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Myeloperoxidase	0	2	0	2
Dihydrofolate reductase	0	8	0	9
Lysine-specific demethylase 4A	0	1	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
hypothetical protein, conserved	4	0	0	4
eyes absent homolog 2 isoform a	2	0	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Thromboxane-A synthase	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
serine/threonine-protein kinase PLK1	7	0	0	7
Motilin receptor	0	1	1	2
60 kDa chaperonin	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	2	0	2
Vpr	2	0	0	2
Cytochrome P450 2B1	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	5	0	7
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Estrogen receptor beta	0	3	1	4
Ghrelin O-acyltransferase	0	1	0	1
Monoglyceride lipase	0	1	0	1
14 kDa phosphohistidine phosphatase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	5
Aromatase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	5	0	5
Aldo-keto reductase family 1 member B1	0	2	0	3
Multidrug resistance associated protein	0	1	0	3
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	2	2	4
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Proton-coupled amino acid transporter 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	2	0	5
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	2	0	2
Beta-2 adrenergic receptor	0	2	0	2
Integrin alpha-4	0	2	0	2
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	4	0	8
Beta-1 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
Histamine H1 receptor	0	4	1	5
Sodium-dependent serotonin transporter	0	3	0	3
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	3	0	3
Cholecystokinin receptor type A	0	1	0	1
Protease	0	4	2	6
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	3	0	0	3
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	2	0	5
Carbonic anhydrase 3	0	1	0	4
Macrophage migration inhibitory factor	0	3	0	3
Carbonic anhydrase 4	0	2	0	5
Carbonic anhydrase 6	0	2	0	5
Carbonic anhydrase 5A, mitochondrial	0	2	0	5
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase 7	0	1	0	4
Carbonic anhydrase	0	0	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase 9	0	3	0	7
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 15	0	1	0	4
Carbonic anhydrase 13	0	1	0	3
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Carbonic anhydrase 14	0	1	0	4
Carbonic anhydrase 5B, mitochondrial	0	1	0	4
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	3	0	3
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	0	2
Protein cereblon	0	7	0	7
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Stromelysin-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Urease subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Urease subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	2	0	2
Cytochrome P450 2C19	0	6	0	7
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Endonuclease 8-like 1	0	1	0	1
Parkin	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
phosphoethanolamine/phosphocholine phosphatase isoform 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Microtubule-associated protein tau	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-2	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	1	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	2	0	2
Sodium/potassium-transporting ATPase subunit gamma	0	2	0	2
WD repeat-containing protein 5	0	3	0	3
Histone-lysine N-methyltransferase 2A	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	2	0	2
Cytosolic endo-beta-N-acetylglucosaminidase	0	2	0	2
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Cathepsin B	0	1	0	1
Prothrombin	0	1	0	1
Trypsin	0	1	0	1
Papain	0	1	0	1
Serine protease hepsin	0	1	0	1
Plasminogen	0	1	0	1
Cathepsin B	0	1	0	1
Cathepsin B	0	2	0	2
Pro-cathepsin H	0	1	0	1
Calpain-1 catalytic subunit	0	1	0	1
Cathepsin K	0	1	0	1
Hepatocyte growth factor activator	0	1	0	1
Transmembrane protease serine 6	0	1	0	1
Cysteine protease	0	1	0	1
Cysteine protease falcipain-3	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
UDP-glucose 6-dehydrogenase	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Tumor necrosis factor	0	1	1	2
Neuraminidase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Platelet-activating factor receptor	1	0	0	1
Cystathionine gamma-lyase	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Cystine/glutamate transporter	0	2	0	2
Hydroxyacid oxidase 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Dipeptidyl peptidase 4	0	3	0	3
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	2	0	2
Tyrosine-protein kinase ABL1	0	1	1	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	5	0	5
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Multidrug resistance-associated protein 1	0	0	0	1
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Dihydrofolate reductase	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Dihydrofolate reductase	0	3	0	4
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	2	0	5
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
pyruvate kinase	3	0	0	3
estrogen receptor beta isoform 1	0	2	0	2
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Serine racemase	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Histone deacetylase 3	0	4	0	4
Nuclear receptor corepressor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Histone deacetylase 4	0	3	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 5	0	3	0	3
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
TSHR protein	1	0	0	1
PINK1	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
pyruvate kinase PKM isoform b	2	0	0	2
Aurora kinase A	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase Lyn	0	1	0	1
Ornithine decarboxylase	2	0	0	2
Mast/stem cell growth factor receptor Kit	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Mitogen-activated protein kinase 1	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Mitogen-activated protein kinase 8	0	1	0	1
Anoctamin-1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Estrogen receptor	0	0	3	3
Estrogen receptor beta	0	0	3	3
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Progesterone receptor	0	4	2	7
5-hydroxytryptamine receptor 3E	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Transporter	0	3	0	3
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	3	0	4
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Glutathione S-transferase omega-1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	2	2	4
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
caspase recruitment domain family, member 15	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Beta lactamase (plasmid)	0	1	0	1
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	3	0	4
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	0	1	1
Gastrin/cholecystokinin type B receptor	0	1	1	2
Protein tyrosine phosphatase type IVA 3	0	1	0	1
Protein S100-B	0	1	1	2
Protein S100-B	0	0	1	1
Acrosin	0	1	0	1
Amiloride-sensitive amine oxidase [copper-containing]	0	1	0	1
Diamine acetyltransferase 1	0	1	0	1
Protein tyrosine phosphatase type IVA 2	0	1	0	1
Protein tyrosine phosphatase type IVA 1	0	1	0	1
Aurora kinase B	0	1	0	1
Protein arginine N-methyltransferase 1	0	3	0	3
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Fatty acid-binding protein, liver	0	1	0	1
Hsf1 protein	0	0	3	4
Synaptic vesicle glycoprotein 2A	0	1	0	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier family 22 member 7	0	1	0	3
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 7	0	2	0	4
Trace amine-associated receptor 5	0	0	3	3
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
Pyridoxal kinase	0	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
tumor necrosis factor	2	0	0	2
D(2) dopamine receptor	0	1	0	1
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Adenine-n6-dna-methyltransferase Taqi	0	0	1	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Ermc' Methyltransferase	0	1	0	1
Chain A, Ermc' Rrna Methyltransferase	0	1	0	1
Chain A, Uroporphyrin-III C-methyltransferase	0	1	0	1
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
tRNA (cytosine(38)-C(5))-methyltransferase	0	1	1	2
Histone-lysine N-methyltransferase SUV39H1	0	2	0	2
Adenosylhomocysteinase	0	0	0	1
Protein arginine N-methyltransferase 3	0	1	0	1
Histone-lysine N-methyltransferase NSD2	0	1	0	1
Adenosylhomocysteinase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
rRNA adenine N-6-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Histone-lysine N-methyltransferase SETDB1	0	1	0	1
Retinoblastoma-binding protein 5	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N6-adenosine-methyltransferase catalytic subunit	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Histone-lysine N-methyltransferase KMT5C	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Histone-lysine N-methyltransferase EZH1	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
Protein dpy-30 homolog	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Histone-lysine N-methyltransferase SUV39H2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N-lysine methyltransferase SMYD2	0	1	0	1
Protein arginine N-methyltransferase 7	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Set1/Ash2 histone methyltransferase complex subunit ASH2	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Non-structural protein 1	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Nitric oxide synthase, brain	0	0	1	1
Acetylcholinesterase	0	2	0	2
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Envelope glycoprotein	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Chain A, Glutathione S-transferase	0	1	0	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Caspase-1	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Adenylate kinase isoenzyme 1	0	0	0	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Capsid protein	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Thymidine kinase, cytosolic	0	0	0	3
Thymidine kinase	0	2	0	4
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	1	0	3
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN	0	0	1	1
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN	0	0	1	1
Chain A, Deoxynucleoside kinase	0	1	0	1
DNA polymerase beta	0	2	0	2
Chain A, Thymidylate Synthase	0	0	1	1
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, PAPAIN	1	0	0	1
putative alpha-glucosidase	1	0	0	1
Cathepsin G	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Chain A, Cytidine Deaminase	0	1	0	1
Uridine-cytidine kinase 1	0	0	0	1
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain B, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, PyrR bifunctional protein	0	0	1	1
Uridine 5'-monophosphate synthase	0	1	0	1
UMP-CMP kinase	0	0	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Protein argonaute-2	0	0	1	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Polyamine deacetylase HDAC10	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 9	0	2	0	2
tyrosine-protein kinase Yes	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (1,144)

Protein Targets (1,653)

Anemia, Megaloblastic

Synonyms(1)

Research Excerpts

Overview

Research

Studies (1,144)

Drugs Studied (258)

Protein Targets (1,653)