Page last updated: 2024-09-28

Jaw Fractures

Fractures of the upper or lower jaw.

Synonyms(1)

Synonym
Jaw Fractures

Research

Studies (153)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990101 (66.01)23.3326
1990's20 (13.07)12.5806
2000's15 (9.80)18.1394
2010's15 (9.80)28.8240
2020's2 (1.31)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lactic acid0medium31
nickel0low10
acetaminophen0low10
alendronate0low10
benzocaine0low10
halothane0low10
hexetidine0low10
lidocaine0low10
labetalol0low10
propranolol0low10
biguanides0medium11
isoprene0low20
methylprednisolone0low10
caprolactam0low10
methohexital0low10
pyrazines0low10
erythromycin0low10
propanidid0low20
benperidol0low10
iodinated glycerol0low10
enbucrilate0low10
tantalum0low10
technetium0low20
titanium0low180
trolamine salicylate0low120
titanium dioxide0low10
amoxicillin0low10
vecuronium bromide0low10
cefmetazole0low10
propiconazole0low100
4-methacryloxyethyltrimellitic acid anhydride0low10
triazoles0low10
inositol 3-phosphate0medium151
pancuronium0low10
retinol0low10
posaconazole0low10
thiopental0low10
codeine0low10
phenylephrine hydrochloride0low160
aluminum0low10
sulfur0low10
phosphorus0low10
chlorhexidine0medium21
jaw0low390
colistin0low10
ascorbic acid0low10
tetracycline0low10
rome0low10
technetium tc 99m medronate0low10

Protein Targets (520)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma130013
ATAD5 protein, partial4004
GLS protein3003
Microtubule-associated protein tau3003
Smad31001
aldehyde dehydrogenase 1 family, member A16006
thyroid stimulating hormone receptor4004
nuclear receptor subfamily 1, group I, member 38008
progesterone receptor6006
EWS/FLI fusion protein2002
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha9009
estrogen-related nuclear receptor alpha170017
estrogen nuclear receptor alpha180018
peroxisome proliferator activated receptor gamma8008
aryl hydrocarbon receptor8008
chromobox protein homolog 16006
thyroid hormone receptor beta isoform 28008
peripheral myelin protein 224004
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi5218
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010010
Solute carrier family 22 member 60202
Carbonic anhydrase 120101
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0303
Voltage-dependent calcium channel gamma-2 subunit7007
Bile salt export pump011011
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20102
Prostaglandin G/H synthase 10101
Carbonic anhydrase 30101
Cytochrome P450 3A40505
Cytochrome P450 2D60404
Cytochrome P450 2C9 0505
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit beta-15218
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta5218
Gamma-aminobutyric acid receptor subunit gamma-25218
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 27007
Gamma-aminobutyric acid receptor subunit alpha-55218
Gamma-aminobutyric acid receptor subunit alpha-35218
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0001
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Gamma-aminobutyric acid receptor subunit gamma-15218
Gamma-aminobutyric acid receptor subunit alpha-25218
Gamma-aminobutyric acid receptor subunit alpha-45218
Gamma-aminobutyric acid receptor subunit gamma-35218
Gamma-aminobutyric acid receptor subunit alpha-65218
Carbonic anhydrase 5A, mitochondrial0101
Prostaglandin G/H synthase 20001
Carbonic anhydrase 70101
Nuclear receptor ROR-gamma3003
Cytochrome P450 2J20404
Gamma-aminobutyric acid receptor subunit alpha-15218
Gamma-aminobutyric acid receptor subunit beta-35218
Gamma-aminobutyric acid receptor subunit beta-25218
Carbonic anhydrase 90101
GABA theta subunit5218
Canalicular multispecific organic anion transporter 1010010
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Gamma-aminobutyric acid receptor subunit epsilon5218
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
toxin B0001
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0101
Farnesyl pyrophosphate synthase0202
Acetylcholinesterase0101
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0101
Farnesyl pyrophosphate synthase 0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, Beta-lactamase4004
Chain A, 2-oxoglutarate Oxygenase2002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0002
AR protein170017
apical membrane antigen 1, AMA11001
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)3003
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
DNA polymerase kappa isoform 12002
Beta-lactamase SHV-10001
Beta-lactamase SHV-10002
Beta-lactamase0002
Kappa-type opioid receptor0001
Solute carrier family 15 member 10303
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20303
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20303
Beta-lactamase 0001
Beta-lactamase 0001
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase6006
GLI family zinc finger 3130013
thioredoxin glutathione reductase1001
cytochrome P450 family 3 subfamily A polypeptide 45005
glucocorticoid receptor [Homo sapiens]100010
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
IDH15005
euchromatic histone-lysine N-methyltransferase 25005
nuclear factor erythroid 2-related factor 2 isoform 23003
nuclear factor erythroid 2-related factor 2 isoform 1130013
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin9009
lethal factor (plasmid)2002
lamin isoform A-delta107007
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0023
Spike glycoprotein6006
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
glp-1 receptor, partial5005
TDP1 protein120012
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
farnesoid X nuclear receptor4004
pregnane X nuclear receptor8008
cytochrome P450 2D65005
peroxisome proliferator-activated receptor delta8008
thyroid stimulating hormone receptor8008
cytochrome P450 2D6 isoform 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
potassium voltage-gated channel subfamily H member 2 isoform d5005
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Rap guanine nucleotide exchange factor 33003
D(2) dopamine receptor0213
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 2A0314
D(3) dopamine receptor0101
Histamine H2 receptor3003
USP1 protein, partial4004
G5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
nuclear receptor ROR-gamma isoform 14004
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 5005
TAR DNA-binding protein 433003
Inositol hexakisphosphate kinase 15005
ATPase family AAA domain-containing protein 55005
Ataxin-27007
cytochrome P450 2C9, partial5005
SMAD family member 26006
SMAD family member 36006
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x5005
Solute carrier family 22 member 80101
Insulin-degrading enzyme0101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase0001
Nuclear receptor subfamily 1 group I member 20022
Solute carrier family 22 member 50101
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0001
Beta-lactamase0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Solute carrier family 22 member 60202
Beta-lactamase 0001
Solute carrier family 22 member 70101
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 110102
Solute carrier family 22 member 80101
Solute carrier family 22 member 70102
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, BCL-2-RELATED PROTEIN A10011
Chain A, Cruzipain3003
Luciferase1001
acid sphingomyelinase2002
interleukin 83003
PAX80001
15-lipoxygenase, partial2002
pregnane X receptor3003
phosphopantetheinyl transferase3003
hypoxia-inducible factor 1 alpha subunit3003
PINK11001
estrogen receptor 2 (ER beta)6006
67.9K protein3003
glucocerebrosidase2002
Parkin1001
heat shock protein 900011
calcineurin A1, putative0011
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
perilipin-50101
thyroid hormone receptor beta isoform a3003
perilipin-10101
transcriptional regulator ERG isoform 31001
heat shock protein beta-13003
huntingtin isoform 21001
importin subunit beta-1 isoform 11001
mitogen-activated protein kinase 13003
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 12002
protein AF-9 isoform a0001
snurportin-11001
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Solute carrier family 22 member 20202
Solute carrier family 22 member 1 0404
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0102
Cellular tumor antigen p535005
Integrin beta-33003
72 kDa type IV collagenase0202
Integrin alpha-IIb3003
Matrix metalloproteinase-90101
Trypanothione reductase0101
Alpha-synuclein1203
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Rap guanine nucleotide exchange factor 41001
Multidrug and toxin extrusion protein 10404
Spermine oxidase0101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
UDP-glucuronosyltransferase 2B70001
Delta-type opioid receptor0101
Kappa-type opioid receptor0101
Mu-type opioid receptor0325
Delta-type opioid receptor0314
Kappa-type opioid receptor0314
Mu-type opioid receptor0101
Potassium voltage-gated channel subfamily H member 20404
Cytochrome P450 2D40101
Mas-related G-protein coupled receptor member X20011
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK11001
streptokinase A precursor0011
Motilin receptor0112
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
Albumin0123
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10404
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
60 kDa heat shock protein, mitochondrial0101
Chitinase B0101
ATP-dependent translocase ABCB10202
Low molecular weight phosphotyrosine protein phosphatase0101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
10 kDa heat shock protein, mitochondrial0101
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0101
50S ribosomal protein L36 20213
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Chymotrypsinogen A0101
ATP-dependent phosphofructokinase2002
thioredoxin reductase7007
Beta-1 adrenergic receptor 0124
Beta-2 adrenergic receptor0426
Aldo-keto reductase family 1 member B10202
Beta-1 adrenergic receptor0426
Beta-3 adrenergic receptor0224
5-hydroxytryptamine receptor 1A0416
Alpha-2B adrenergic receptor0022
Alpha-2C adrenergic receptor0022
Alpha-2A adrenergic receptor0022
Sodium-dependent noradrenaline transporter 0202
Alpha-1D adrenergic receptor0225
5-hydroxytryptamine receptor 1B0404
Alpha-1A adrenergic receptor0135
Alpha-1B adrenergic receptor0023
5-hydroxytryptamine receptor 2B0415
Sodium-dependent dopamine transporter 0202
Beta-2 adrenergic receptor0124
Sigma non-opioid intracellular receptor 10404
Heparanase0011
muscarinic acetylcholine receptor M11001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
PPM1D protein1001
nonstructural protein 12002
bromodomain adjacent to zinc finger domain 2B1001
nuclear receptor subfamily 1, group I, member 21001
muscleblind-like protein 1 isoform 11001
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0404
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nuclear receptor subfamily 1 group I member 20011
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
5-hydroxytryptamine receptor 70202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
arylsulfatase A2002
serine/threonine-protein kinase mTOR isoform 11001
GALC protein1001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 11001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Sterol 14-alpha-demethylase0011
Fumarate hydratase1001
polyprotein1001
14-alpha sterol demethylase 0011
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Lanosterol 14-alpha demethylase0011
Aromatase0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
14-alpha sterol demethylase 0011
14-alpha sterol demethylase 0011
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Chain A, Ferritin light chain2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
vitamin D3 receptor isoform VDRA2002
heat shock protein HSP 90-alpha isoform 20102
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
D(1A) dopamine receptor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Muscarinic acetylcholine receptor M20213
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0124
Adenosine receptor A30112
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
Muscarinic acetylcholine receptor M10112
Alpha-1B adrenergic receptor0213
Beta-1 adrenergic receptor0214
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
Muscarinic acetylcholine receptor M30112
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-1D adrenergic receptor0213
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2C0213
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Vasopressin V1a receptor0112
Alpha-1A adrenergic receptor0213
5-hydroxytryptamine receptor 60213
Beta-2 adrenergic receptor0101
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Disintegrin and metalloproteinase domain-containing protein 171001
Sphingosine kinase 20202
Sphingosine kinase 10101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Stromelysin-10101
Multidrug transporter MdfA0101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40101
histone acetyltransferase KAT2A isoform 11001
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]