nitrogen mustard

Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

ChEBI ID: 37598

Members (12)

Member	Definition	Role
4-hydroxycyclophosphamide	A phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen.	4-hydroxycyclophosphamide
4-ketocyclophosphamide		4-Ketocyclophosphamide
aldophosphamide		Aldophosphamide
carboxyphosphamide		Carboxyphosphamide
chlorambucil	A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.	chlorambucil
mechlorethamine		mechlorethamine
mechlorethamine n-oxide		Nitrogen mustard N-oxide
melphalan	A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.	melphalan
nornitrogen mustard		bis(2-chloroethyl)amine
perfosfamide	A phosphorodiamide that is the active metabolite of the nitrogen mustard cyclophosphamide. It has potent antineoplastic and immunosuppressive properties.	4-hydroperoxycyclophosphamide
phosphoramide mustard		phosphoramide mustard
uracil mustard		5-[bis(2-chloroethyl)amino]uracil