Page last updated: 2024-08-05 11:51:19

cyclopentanes

Cyclopentane and its derivatives formed by substitution.

ChEBI ID: 23493

Members (6)

MemberDefinitionRole
1-(1-phenylcyclopentyl)methylamine1-(1-phenylcyclopentyl)methylamine
b 43A member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively).RK-24466
cyclopentaneA cycloalkane that consists of five carbons each bonded with two hydrogens above and below the plane. The parent of the class of cyclopentanes.cyclopentane
N-([biphenyl]-2-yl)-3-cyclopentylpropanamideA secondary carboxamide resulting from the formal condensation of the carboxy group of 3-cyclopentylpropionic acid with the amino group of [biphenyl]-2-amine.N-([biphenyl]-2-yl)-3-cyclopentylpropanamide
palbociclibA member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer.palbociclib
PP121A pyrazolopyrimidine that is 1H-pyrazolo[3,4-d]pyrimidine which is substituted by a cyclopentyl, 1H-pyrrolo[2,3-b]pyridin-5-yl, and amino groups at positions 1, 3 and 4, respectively. It is a dual inhibitor of tyrosine and phosphoinositide kinases and exhibits anti-cancer properties.PP121

Research

Studies (11,215)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990908 (8.10)18.7374
1990's1,212 (10.81)18.2507
2000's2,569 (22.91)29.6817
2010's4,951 (44.15)24.3611
2020's1,575 (14.04)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials212 (1.85%)5.53%
Reviews673 (5.87%)6.00%
Case Studies91 (0.79%)4.05%
Observational19 (0.17%)0.25%
Other10,469 (91.32%)84.16%