Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
| Member | Definition | Class |
|---|
| ((5z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4h-imidazol-4-one) | A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 muM, respectively). | leucettine L41 |
| 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | A member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. | 3PO |
| AZ3451 | A member of the class of benzimidazoles that is 1H-benzimidazole substituted by (1S)-1-cyclohexylethyl, 6-bromo-1,3-benzodioxol-5-yl, and 4-(cyanoanilino)acyl groups at positions 1, 2 and 5, respectively. It is an allosteric modulator of protease-activated receptor 2 (IC50 = 23 nM) and exhibits anti-osteoarthritis properties. | AZ3451 |
| AZD3463 | A member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. | AZD3463 |
| bay 11-7085 | A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB. | BAY11-7085 |
| diethylstilbestrol | An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. | diethylstilbestrol |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| gsk 2126458 | A member of the class of quinolines that is quinoline which is substituted by pyridazin-4-yl and 5-[(2,4-difluorobenzene-1-sulfonyl)amino]-6-methoxypyridin-3-yl groups at positions 4 and 6, respectively. It is a highly potent inhibitor of PI3K and mTOR developed by GlaxoSmithKline and was previously in human phase 1 clinical trials for the treatment of idiopathic pulmonary fibrosis and solid tumors. | omipalisib |
| ly3009120 | A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAF(V600E), BRAF(WT) and CRAF(WT) (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties. | LY3009120 |
| mocetinostat | A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11). | mocetinostat |
| N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide | A hydroxamic acid that is N-hydroxy-D-valinamide in which the alpha-amino group has been substituted by isopropoxy and [biphenyl]-4-ylsulfonyl groups. A selective matrix metalloproteinase-2 (MMP-2) inhibitor, it is one of the most potent inducers of autophagy. Its physiological roles include angiogenesis, cancer metastasis, embryogenesis, tissue remodeling in development, and wound healing. | N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide |
| salvigenin | A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups. | salvigenin |
| saracatinib | A member of the class of quinazolines that is quinazoline substituted by (5-chloro-2H-1,3-benzodioxol-4-yl)amino, (oxan-4-yl)oxy and 2-(4-methylpiperazin-1-yl)ethoxy groups at positions 4, 5 and 7, respectively. It is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). Saracatinib was originally developed by AstraZeneca for the treatment of cancer but in 2019 it was granted orphan drug designation by the US Food and Drug Administration for the treatment of idiopathic pulmonary fibrosis (IPF), a type of lung disease that results in scarring (fibrosis) of the lungs. | saracatinib |
| SMER 28 | A member of the class of quinazolines that is quinazoline which is substituted by a prop-2-en-1-ylnitrilo group and a bromo group at positions 4 and 6, respectively. It is a modulator of mammalian autophagy. | SMER 28 |
| spermidine | A triamine that is the 1,5,10-triaza derivative of decane. | spermidine |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 17.5594 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 12.5893 | 1 | 2 |
| 67.9K protein | Vaccinia virus | Potency | 5.0119 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 0.7762 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 54.5111 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.7022 | 1 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 15.8174 | 1 | 4 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 1.1582 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 27.7715 | 7 | 17 |
| arylsulfatase A | Homo sapiens (human) | Potency | 7.5686 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 19.8897 | 3 | 8 |
| Ataxin-2 | Homo sapiens (human) | Potency | 19.7312 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 37.9330 | 1 | 1 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 11.9955 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 7.3621 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 0.0056 | 2 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 20.9924 | 3 | 7 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 23.7358 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 22.3872 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 7.7038 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 12.5893 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 59.4873 | 2 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 17.3382 | 1 | 3 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 18.9969 | 1 | 3 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 5.8805 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 64.6116 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 6.8739 | 2 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 5.8479 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.0911 | 11 | 29 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 23.3237 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 38.5934 | 10 | 20 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 4.3586 | 1 | 4 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 8.7724 | 4 | 13 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 45.4422 | 3 | 6 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 22.8988 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 17.3382 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 17.4028 | 3 | 5 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 22.9658 | 2 | 6 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 19.0481 | 2 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 28.6493 | 4 | 9 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 54.2612 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 2.9309 | 2 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 36.1214 | 2 | 4 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 11.8042 | 2 | 11 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 31.2489 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 125.7890 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 17.3382 | 1 | 3 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 8.4921 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 47.2868 | 2 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 17.3382 | 1 | 6 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.3377 | 2 | 18 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 9.2057 | 2 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.8489 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 26.7640 | 2 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 20.3805 | 1 | 3 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 8.9125 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 16.2710 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 1.9514 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 3,690.4390 | 1 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 11.5821 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.4478 | 3 | 8 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 27.5004 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 22.3872 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 8.2188 | 3 | 7 |
| Parkin | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 0.0675 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 32.1968 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 8.4921 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 34.6238 | 3 | 6 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 46.7037 | 3 | 3 |
| polyprotein | Zika virus | Potency | 22.8988 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 11.5098 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 40.0748 | 1 | 2 |
| PPM1D protein | Homo sapiens (human) | Potency | 8.9377 | 1 | 10 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 40.4288 | 3 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 23.8620 | 1 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 35.7188 | 2 | 6 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 69.3652 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 36.8665 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 37.6919 | 3 | 4 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 36.1095 | 4 | 6 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.9306 | 4 | 5 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 31.6228 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 24.8033 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 15.4186 | 2 | 6 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 1.1444 | 2 | 4 |
| Thrombopoietin | Homo sapiens (human) | Potency | 6.3096 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 20.3453 | 3 | 8 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 44.9647 | 1 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 45.2479 | 3 | 6 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| TSHR protein | Homo sapiens (human) | Potency | 42.5615 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 11.5020 | 2 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 69.2547 | 1 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 61.1624 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.9009 | 2 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 47.7174 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 54.2612 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 2.9350 | 4 | 4 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 4.7900 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 1.3690 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 3.1400 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 1.9980 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 50.8190 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 26.6190 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 50.8190 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 26.6190 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 12.8920 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 5.9860 | 1 | 1 |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | Homo sapiens (human) | IC50 | 49.3000 | 3 | 3 |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | Homo sapiens (human) | Ki | 25.1000 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 0.0006 | 3 | 3 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 25.5500 | 1 | 1 |
| Acyl-homoserine lactone acylase PvdQ | Pseudomonas aeruginosa PAO1 | IC50 | 65.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 2.8560 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 1.6660 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 9.0130 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 5.0600 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 2.2080 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.2480 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.4600 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 3.6700 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 3.6400 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2080 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.2480 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2080 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.2480 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 10.8260 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 5.3210 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 14.1270 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0012 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 5.2970 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 11.6980 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0012 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 5.3400 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 15.1510 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0012 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 2.2010 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 14.1254 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 22.0880 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 12.7550 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 0.5000 | 2 | 2 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 4.1770 | 1 | 1 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 1.6140 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 0.3140 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 11.6000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 91.5000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 1.4000 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 44.1000 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 11.6000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 91.5000 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 1.1100 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 11.5000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 0.1120 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 1.2200 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 1.4400 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 1.4100 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 1.2300 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 1.3700 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.4150 | 2 | 2 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.4150 | 2 | 2 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.4150 | 2 | 2 |
| Chain A, Acyl-homoserine lactone acylase pvdQ | Pseudomonas aeruginosa PAO1 | IC50 | 65.0000 | 1 | 2 |
| Chain A, Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.0027 | 1 | 1 |
| Chain B, Acyl-homoserine lactone acylase pvdQ | Pseudomonas aeruginosa PAO1 | IC50 | 65.0000 | 1 | 2 |
| Collagenase 3 | Homo sapiens (human) | IC50 | 0.0041 | 1 | 1 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 20.0000 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 16.6667 | 3 | 3 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 13.4700 | 3 | 3 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 14.0000 | 2 | 2 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 13.4700 | 3 | 3 |
| Cyclin-H | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 14.0000 | 2 | 2 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 17.7450 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | Ki | 8.8720 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.0012 | 1 | 2 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 0.1020 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 0.1020 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 0.1292 | 4 | 5 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 6.0875 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 3.0440 | 1 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 13.3210 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 4.4400 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 6.1280 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 2.0810 | 1 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 2.7180 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 13.4790 | 2 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 17.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | IC50 | 17.0000 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | IC50 | 0.0710 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 0.0360 | 4 | 4 |
| Dual specificity protein kinase CLK2 | Mus musculus (house mouse) | IC50 | 0.3900 | 3 | 3 |
| Dual specificity protein kinase CLK3 | Mus musculus (house mouse) | IC50 | 6.0500 | 4 | 4 |
| Dual specificity protein kinase CLK4 | Mus musculus (house mouse) | IC50 | 0.0393 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 0.0371 | 6 | 6 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 0.0300 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | IC50 | 0.0550 | 4 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | IC50 | 0.0855 | 4 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | IC50 | 0.4167 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Homo sapiens (human) | IC50 | 0.5200 | 1 | 1 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| Elastase | Pseudomonas aeruginosa PAO1 | IC50 | 427.5000 | 2 | 2 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | IC50 | 0.0200 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | GI50 | 0.1315 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 1.9615 | 4 | 4 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 0.1312 | 6 | 6 |
| Estrogen receptor | Homo sapiens (human) | Ki | 0.0002 | 5 | 5 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 0.1588 | 4 | 4 |
| Estrogen receptor beta | Homo sapiens (human) | Ki | 0.0003 | 3 | 3 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 10.6000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 0.2100 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 5.1900 | 2 | 2 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 2.9350 | 4 | 4 |
| GTPase KRas | Homo sapiens (human) | IC50 | 0.1500 | 1 | 1 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 12.5893 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 2.4892 | 17 | 27 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 0.0090 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 4.9592 | 4 | 13 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 3.5691 | 9 | 18 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 0.0324 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 3.4180 | 11 | 21 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 0.2650 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 6.2287 | 5 | 15 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 7.3350 | 5 | 14 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 8.6016 | 9 | 19 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 7.3350 | 5 | 14 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 11.7306 | 7 | 16 |
| Huntingtin | Homo sapiens (human) | IC50 | 5.3600 | 1 | 1 |
| Integrin alpha-4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Integrin beta-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 0.3185 | 2 | 2 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 5.0355 | 2 | 2 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 4.5630 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 1.8250 | 1 | 1 |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Macrophage metalloelastase | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | IC50 | 0.2000 | 3 | 3 |
| Matrilysin | Homo sapiens (human) | IC50 | 6.0555 | 1 | 2 |
| Matrix metalloproteinase-14 | Homo sapiens (human) | IC50 | 0.0098 | 2 | 2 |
| Matrix metalloproteinase-16 | Homo sapiens (human) | IC50 | 0.0510 | 1 | 1 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 0.0067 | 3 | 3 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | IC50 | 5.2090 | 2 | 2 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Ki | 2.6199 | 2 | 2 |
| Mitogen-activated protein kinase 1 | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 5.2350 | 2 | 2 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 0.0610 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 0.0610 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 0.0610 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 16.4820 | 2 | 2 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | IC50 | 5.2350 | 2 | 2 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 5.2350 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | IC50 | 0.0980 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | IC50 | 0.0390 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 0.9700 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 5.7780 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 2.3450 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 15.1710 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 3.6540 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 18.4320 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 3.9070 | 1 | 1 |
| Neutrophil collagenase | Homo sapiens (human) | IC50 | 0.0016 | 2 | 2 |
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | IC50 | 6.7890 | 1 | 1 |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | IC50 | 2.2990 | 1 | 1 |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | IC50 | 0.0450 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | IC50 | 14.6000 | 1 | 1 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens (human) | IC50 | 0.0000 | 1 | 1 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens (human) | Ki | 0.0002 | 3 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 0.0006 | 9 | 9 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Ki | 0.0000 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | IC50 | 0.0009 | 5 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Ki | 0.0003 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 0.0014 | 5 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Ki | 0.0000 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 0.0006 | 5 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Ki | 0.0003 | 2 | 2 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 2.9630 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Proteinase-activated receptor 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Proteinase-activated receptor 2 | Homo sapiens (human) | IC50 | 3.3012 | 2 | 2 |
| Proteinase-activated receptor 4 | Homo sapiens (human) | IC50 | 0.3800 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 1.5230 | 12 | 14 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 1.4100 | 1 | 1 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0230 | 4 | 4 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Ki | 0.0001 | 2 | 2 |
| Rapamycin-insensitive companion of mTOR | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.4733 | 3 | 3 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 0.8400 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 14.0000 | 1 | 1 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | IC50 | 0.0297 | 3 | 3 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 0.6620 | 9 | 9 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Ki | 0.0001 | 2 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.0006 | 8 | 8 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 4.0450 | 4 | 4 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | IC50 | 0.7100 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 1.0710 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.8510 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 3.6700 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 3.6400 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 12.4920 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 6.6370 | 1 | 1 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 0.0500 | 2 | 2 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 9.5530 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 3.1840 | 1 | 1 |
| Target of rapamycin complex 2 subunit MAPKAP1 | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
| Thermolysin | Bacillus thermoproteolyticus | IC50 | 608.0000 | 2 | 2 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 4.3590 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 5.9580 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 0.1175 | 4 | 4 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | IC50 | 0.7025 | 4 | 4 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 7.1620 | 2 | 2 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 0.0040 | 3 | 3 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 0.0038 | 5 | 5 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 13.3405 | 4 | 5 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 25.9250 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | Ki | 10.4010 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 17.3250 | 1 | 2 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 15.0020 | 1 | 2 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 15.0710 | 1 | 2 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 16.9390 | 1 | 2 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 2.9000 | 1 | 1 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 20.0917 | 1 | 3 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Aurora kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 15.0300 | 1 | 2 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 15.0145 | 1 | 2 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 15.0080 | 1 | 2 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 15.0540 | 1 | 2 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 36.1400 | 1 | 2 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 20.0250 | 2 | 3 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 20.1200 | 2 | 3 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 15.5500 | 2 | 2 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 20.0233 | 2 | 3 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 22.5020 | 2 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 0.1400 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 0.4500 | 1 | 1 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 0.0100 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 10.3557 | 2 | 3 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 15.4585 | 1 | 2 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 16.1905 | 1 | 2 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 19.7075 | 1 | 2 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 16.9390 | 1 | 2 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 16.8010 | 1 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 17.2005 | 1 | 2 |
| Estrogen receptor | Homo sapiens (human) | EC50 | 0.0025 | 5 | 5 |
| Estrogen receptor beta | Homo sapiens (human) | EC50 | 0.0045 | 2 | 2 |
| Estrogen-related receptor gamma | Homo sapiens (human) | EC50 | 0.6300 | 2 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 22.6375 | 2 | 4 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 0.3200 | 1 | 1 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 0.2300 | 1 | 1 |
| Huntingtin | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 20.3100 | 2 | 3 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 16.5165 | 1 | 2 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 20.9390 | 2 | 3 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 16.4925 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 15.5605 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 28.5440 | 1 | 2 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Nucleoside diphosphate kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 15.6860 | 1 | 2 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 15.3155 | 1 | 2 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Procathepsin L | Homo sapiens (human) | EC50 | 2.9000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 15.2830 | 1 | 2 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 15.0890 | 1 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 15.0660 | 1 | 2 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Putative nucleoside diphosphate kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 15.0010 | 1 | 2 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 15.8840 | 1 | 2 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 15.0700 | 1 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 2.9000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 2.9000 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 2.9000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 2.9000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 2.9000 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 20.8405 | 1 | 2 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | EC50 | 5.0050 | 2 | 2 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | EC50 | 5.0050 | 2 | 2 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | EC50 | 5.0050 | 2 | 2 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 15.7035 | 1 | 2 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 17.4255 | 1 | 2 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 20.5667 | 2 | 3 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 2.9000 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 2.9000 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.8565 | 1 | 2 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 15.0985 | 1 | 2 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 15.6875 | 1 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 2.9000 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 15.0265 | 1 | 2 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 15.0455 | 1 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 20.0765 | 1 | 2 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 34.7765 | 1 | 2 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 0.9560 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 16.1650 | 1 | 2 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 15.0490 | 1 | 2 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 15.0500 | 1 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 15.0045 | 1 | 2 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 15.0565 | 1 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 15.0475 | 1 | 2 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |