Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
| Member | Definition | Class |
|---|
| (3E,9E)-5,6-Dihydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-3,9,12-triene-2,18-dione | | (3E,9E)-5,6-Dihydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-3,9,12-triene-2,18-dione |
| 1-octen-3-ol | An alkenyl alcohol with a structure based on a C8 unbranched chain with the hydroxy group at C-2 and unsaturation at C-1-C-2. It is a major volatile compound present in many mushrooms and fungi. | oct-1-en-3-ol |
| 1,8-dihydroxynaphthalene | A member of the class of naphthalenediols that is naphthalene in which the hydrogens at positions 1 and 8 are replaced by hydroxy groups. | naphthalene-1,8-diol |
| 2-ethylhexanal | A saturated fatty aldehyde that is heptane in which one of the hydrogens at position 3 has been replaced by a formyl group. It is a metabolite of the plasticisers di-2-ethylhexyl phthalate (DEHP) and di-2-ethylhexyl adipate (DEHA). | 2-ethylhexanal |
| 2,5-dihydroxybenzoic acid | A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions. | 2,5-dihydroxybenzoic acid |
| 2,5-dihydroxybenzyl alcohol | An aromatic primary alcohol that is benzyl alcohol substituted by hydroxy groups at positions 2 and 5. | gentisyl alcohol |
| 2'-o-methyladenosine | A member of the class of adenosines that is adenosine in which the hydroxy group at position 2' is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis. | cordysinin B |
| 3-hydroxybutyric acid | The R-enantiomer of 3-hydroxybutyric acid. Involved in the synthesis and degradation of ketone bodies, it can be used as an energy source by the brain during hypoglycaemia, and for the synthesis of biodegradable plastics. It is a sex pheremone in the European spider Linyphia triangularis. | (R)-3-hydroxybutyric acid |
| 3-methylfuran | A member of the class of furans that is furan in which the hydrogen at position 3 is replaced by a methyl group. It is a chemical that is produced in foods during food processing and preservation techniques that involve heat treatment such as cooking and pasteurization. | 3-methylfuran |
| 3-octanone | A dialkyl ketone that is octane in which the two methylene protons at position 3 have been replaced by an oxo group. | 3-octanone |
| 4-hydroxyacetophenone | A monohydroxyacetophenone carrying a hydroxy substituent at position 4'. | 4'-hydroxyacetophenone |
| 4-hydroxyphenylacetic acid | A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. | 4-hydroxyphenylacetic acid |
| 4-hydroxyphenylethanol | A phenol substituted at position 4 by a 2-hydroxyethyl group. | 2-(4-hydroxyphenyl)ethanol |
| 5-hydroxybenzofuran-2-one | A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a hydroxy group at position 5. | 5-hydroxybenzofuran-2-one |
| 5-hydroxymethyl-2-furoic acid | A member of the class of furoic acids that is 2-furoic acid substituted at position 5 by a hydroxymethyl group. | 5-hydroxymethyl-2-furoic acid |
| 5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one | A member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. | rohitukine |
| 8,11,14-eicosatrienoic acid | An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14. | all-cis-icosa-8,11,14-trienoic acid |
| acromelic acid a | A pyrrolidinecarboxylic acid that is siolated from the poisonous mushroom Clitocybe amoenolens. | acromelic acid A |
| acrylonitrile | A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an ethenyl group. | acrylonitrile |
| acuminatin | A neolignan that is 5-[(1E)-prop-1-en-1-yl]-2,3-dihydro-1-benzofuran carrying additional 3,4-dimethoxyphenyl, methyl and methoxy substituents at positions 2, 3 and 7 respectively. | acuminatin |
| albicanol | A drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities. | (+)-albicanol |
| altenusin | A carboxybiphenyl that is [biphenyl]-2-carboxylic acid which is substituted by a hydroxy group at positions 3, 4' and 5', methoxy group at position 5 and a methyl group at position 2'. It is a a metabolite isolated from Alternaria and several other fungal species. | altenusin |
| alternariol monomethyl ether | A benzochromenone that is alternariol in which the hydroxy group at position 9 has been converted into the corresponding methyl ether. A natural product found in Chaetomium globosum as well as being one of the two most important compounds belonging to the group of Altenaria mycotoxins. | djalonensone |
| antroquinonol d | An enone that is cyclohex-2-en-1-one substituted by a hydroxy group at position 4, methoxy groups at positions 2 and 3, a methyl group at position 6 and a (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl group at position 5 (the 4R,5R,6R stereoisomer). It is isolated from the solid-state fermented mycelium of the fungus Antrodia camphorata and has been found to exhibit potent cytotoxicity against a number of human cancer cell lines. However, a synthesis-enabled biological re-examination published in 2016, revealed minimal in vitro and in vivo antitumour activity in preclinical models. | antroquinonol |
| aphidicolin | A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. | aphidicolin |
| ascochlorin | A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (1E,3E)-3-methyl-1-[(1R,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl]penta-1,3-dien-5-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by several fungi including Ascochyta viciae . It exhibits anticancer, antifungal and antiprotozoal activities. | ascochlorin |
| ascofuranone | A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by the soil fungus, Acremonium sclerotigenum. It is a promising drug candidate against the tropical disease, African trypanosomiasis. | ascofuranone |
| asperfuranone | A member of the class of 2-benzofurans that is 6,7-dihydro-2-benzofuran-4(5H)-one that is substituted at positions 5 and 6 by hydroxy groups, at position 5 by a methyl group and at position 1 by a (2E,4E,6S)-4,6-dimethylocta-2,4-dienoyl group (the 5S,6R-diastereoisomer). A polyketide that was first obtained from the fungus Aspergillus nidulans by using a genomic mining approach. | asperfuranone |
| atromentin | A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione which is substituted by a 4-hydroxyphenyl group at positions 3 and 6. It is a mushroom pigment isolated from several fungi species and acts as a smooth muscle stimulant, and exhibits anticoagulant, antibacterial and antineoplastic properties. | atromentin |
| averufin | An organic heteropentacyclic compound that is 3,4,5,6-tetrahydro-2H-2,6-epoxyanthra[2,3-b]oxocine-8,13-dione substituted at position 2 by a methyl group and at positions 7, 9 and 11 by hydroxy groups (the S,S-diastereomer) | (1'S,5'S)-averufin |
| baeocystin | A tryptamine alkaloid that is N-methyltryptamine carrying an additional phosphoryloxy substituent at position 4. | baeocystin |
| bassianolide | A cyclodepsipeptide consisting of a cyclic tetramer of the depsipeptide D-Hiv-N-methyl-L-leucine (where D-Hiv = D-alpha-hydroxyisovaleric acid). Found in the fungal species Beauveria bassiana and Verticillium lecanii, it has insecticidal properties and is used as a commercial biopesticide to control of insects of agricultural, veterinary and medical significance. For elucidation of the structure, see Suzuki et al., Tetrahedron Lett. 1977 v25, 2167-2170. | bassianolide |
| beauvericin | A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues. | beauvericin |
| caffeine | A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. | caffeine |
| canthaxanthin | A carotenone that consists of beta,beta-carotene bearing two oxo substituents at positions 4 and 4'. | canthaxanthin |
| cephalosporin c | A cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N(6)-L-lysino group at position 7. | cephalosporin C |
| cercosporamide | A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. | cercosporamide |
| deoxyfuconojirimycin | A hydroxypiperidine in which the three hydroxy substituents are located at positions 3, 4 and 5 together with an additional methyl substituent at position 2. | deoxyfuconojirimycin |
| depudecin | A polyketide obtained from the fungus Alternaria brassicicola and having a highly unusual structure of an 11-carbon chain containing two epoxides and six stereogenic centres. It is an inhibitor of histone deacetylase (HDAC) both in vivo and in vitro and also exhibits anti-angiogenic activity. | depudecin |
| diorcinol | An aromatic ether that is diphenyl ether in which both phenyl groups are substituted at position 3 by a hydroxy group and at position 5 by a methyl group. | diorcinol |
| ebericol | A tetracyclic triterpenoid that is 24,25-dihydrolanosterol carrying an additional methylene substituent at position 24. A natural product found in Taiwanofungus camphoratus. | eburicol |
| eicosapentaenoic acid | An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. | all-cis-5,8,11,14,17-icosapentaenoic acid |
| ellagic acid | An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. | ellagic acid |
| emodin anthrone | A member of the class of anthracenones that is anthracen-9(10H)-one which carries a methyl group at position 6 and hydroxy groups at positions 1, 3 and 8, respectively. It is an intermediate precursor in the synthesis of hypericin. | emodin anthrone |
| equisetin | A member of the class of tetramic acids that is trichosetin in which the hydrogen attached to the lactam nitrogen has been replaced by a methyl group. It is produced by the filamentous fungus Fusarium heterosporum. | equisetin |
| ergonovine | A monocarboxylic acid amide that is lysergamide in which one of the hydrogens attached to the amide nitrogen is substituted by a 1-hydroxypropan-2-yl group (S-configuration). An ergot alkaloid that has a particularly powerful action on the uterus, its maleate (and formerly tartrate) salt is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by maintaining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced. | ergometrine |
| ergosine | An ergot alkaloid isolated from the fungus Epichloe typhina. | ergosine |
| ergosta-4,6,8(14),22-tetraen-3-one | An ergostanoid that is (22E)-ergosta-4,6,8(14),22-tetraene substituted by an oxo group at position 3. It has been isolated from the mycelia of Cordyceps sinensis. | ergosta-4,6,8(14),22-tetraen-3-one |
| ergosterol | A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group. | ergosterol |
| ergothioneine | A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs. | ergothioneine thione form; ergothioneine |
| ergothioneine | A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a thioxo group. | ergothioneine thione form; ergothioneine |
| fibrinogen | The D-enantiomer of iditol. | D-iditol |
| fumagillin | A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. | fumagillin |
| gamma-dodecalactone | A gamma-lactone that is oxolan-2-one substituted by an octyl group at position 5. | gamma-dodecalactone |
| gamma-guanidinobutyric acid | The 4-guanidino derivative of butanoic acid. | 4-guanidinobutanoic acid zwitterion; 4-guanidinobutanoic acid; 4-guanidinobutyric acid |
| ganodermadiol | A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species. | ganoderol B |
| glycitein | A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis. | glycitein |
| helvolic acid | A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24. | helvolic acid |
| hispidin | Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus). | hispidin |
| HT-2 toxin | A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin. | HT-2 toxin |
| hypothemycin | A macrolide that is isolated from the cultured broth of Hypomyces subiculosus and shows antifungal activity and inhibits the growth of some human cancer cells. | hypothemycin |
| iditol | The L-enantiomer of iditol. | L-iditol |
| indoleacetamide | A member of the class of indoles that is acetamide substituted by a 1H-indol-3-yl group at position 2. It is an intermediate in the production of plant hormone indole acetic acid (IAA). | indole-3-acetamide |
| itaconic acid | A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group. | itaconic acid |
| lenticin | An amino acid betaine obtaine by exhaustive methylation of the alpha-amino group of L-tryptophan with concomitant deprotonation of the carboxy group. | hypaphorine |
| methyl cinnamate | The E (trans) isomer of methyl cinnamate. | methyl trans-cinnamate |
| methyl n-methylanthranilate | A methyl ester resulting from the formal condensation of the carboxy group of N-methylanthranilic acid with methanol. | methyl N-methylanthranilate |
| mevalonolactone | A 4-hydroxy-4-methyloxan-2-one that has (R)-configuration. It is a natural product found in Phomopsis archeri. | (R)-mevalonolactone |
| mevastatin | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. | mevastatin |
| ml 236a | A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity. | compactin diol lactone |
| monacolin j | A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8. | monacolin J |
| monascin | An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl and methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of carcinogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours. | monascin |
| monascorubrin | | monascorubrin |
| mucidin | An enoate ester that is the methyl ester of (2E,3Z,5E)-2-(methoxymethylene)-3-methyl-6-phenylhexa-3,5-dienoic acid. | mucidin |
| muscimol | A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita. | muscimol |
| nebularine | A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage. | nebularine |
| nonadecanoic acid | A C19 straight-chain fatty acid of plant or bacterial origin. An intermediate in the biodegradation of n-icosane, it has been shown to inhibit cancer growth. | nonadecanoic acid |
| norharman | The parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring. | beta-carboline |
| norlichexanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 8. It has been isolated from Wardomyces anomalus. | norlichexanthone |
| norsolorinic acid | A polyketide that is anthraquinone bearing four hydroxy substituents at positions 1, 3, 6 and 8 as well as a hexanoyl substituent at position 2. | norsolorinic acid |
| orobol | A member of the class of 7-hydroxyisoflavones which consists of isoflavone substituted by hydroxy groups at positions 5, 7, 3' and 4'. It has been isolated from the mycelia of Cordyceps sinensis. | orobol |
| orotidine | A nucleoside formed by attaching orotic acid to a ribose ring via a beta-N(1)-glycosidic bond. | orotidine |
| orsellinic acid | A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group. | o-orsellinic acid |
| poricoic acid a | A tricyclic triterpenoid isolated from Poria cocos. | poricoic acid A |
| poricoic acid g | A tricyclic triterpenoid isolated from Poria cocos. | poricoic acid G |
| prosomatostatin | A heterodetic cyclic peptide consisting of somatostatin in which the amino terminus has been acylated by the fourteen membered peptide Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys. | somatostatin-28 |
| psilocin | A tryptamine alkaloid that is N,N-dimethyltryptamine carrying an additional hydroxy substituent at position 4. A hallucinogenic alkaloid isolated in trace amounts from Psilocybe mushrooms (also known as Teonanacatl or "magic mushrooms"). | psilocin |
| psilocybin | A tryptamine alkaloid that is N,N-dimethyltryptamine carrying an additional phosphoryloxy substituent at position 4. The major hallucinogenic alkaloid isolated from Psilocybe mushrooms (also known as Teonanacatl or "magic mushrooms"). | psilocybin |
| rhodotorulic acid | A member of the class of 2,5-diketopiperazines obtained by cyclodimerisation of N(5)-acetyl-N(5)-hydroxy-L-ornithine. | rhodotorulic acid |
| rubrofusarin | A member of the class of benzochromenones that is benzo[g]chromen-4-one carrying two additional hydroxy substituents at positions 5 and 6 as well as methyl and methoxy substituents at positions 2 and 8 respectively. An orange polyketide pigment that is a common intermediate in many different fungal biosynthetic pathways. | rubrofusarin |
| saintopin | A member of the class of tetracenequinones that is tetracene-5,12-dione in which the hydrogens at positions 1, 3, 8, 10, and 11 have been replaced by hydroxy groups. Isolated from Paecilomyces. | saintopin |
| siccanin | | Siccanin |
| sordaricin | A tetracyclic diterpenoid that is produced by several fungi including Sordaria araneosa. | sordaricin |
| sporothriolide | A furofuran that is (3aR,6aR)-hexahydrofuro[3,4-b]furan substituted by an oxo group at positions 2 and 4, methylene group at position 3 and by an hexyl group at position 6. It is a metabolite isolated from several species of fungi. | sporothriolide |
| squalestatin 1 | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid A |
| strobilurin b | An enoate ester that is the methyl ester of (2E,3Z,5E)-6-(4-chloro-3-methoxyphenyl)-2-(methoxymethylene)-3-methylhexa-3,5-dienoic acid. | strobilurin B |
| sulfur | A homomonocyclic compound composed of eight sulfur atoms. It has been isolated from Ganoderma lucidum, a mushroom commonly used in Chinese medicine. | cyclooctasulfur |
| t-2 toxin | A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. | T-2 toxin |
| theophylline | A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. | theophylline |
| thermozymocidin | An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. | myriocin |
| tmc-95a | A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. It includes a R-hydroxy group at position 11 and a (3-methyl-2-oxopentanoyl)amino group at position at position 18 with a S-methyl group. It acts as a proteasome inhibitor and is obtained from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. | TMC-95A |
| tmc-95b | A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. A stereoisomer of TMC-95A, it has a [(3R)-3-methyl-2-oxopentanoyl]amino group at position 18. It acts as a proteasome inhibitor and is isolated from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. | TMC-95B |
| trachyspic acid | An oxaspiro compound that is 1,6-dioxaspiro[4.4]non-2-en-4-one substituted by a carboxymethyl group at position 2, carboxy groups at positions 2 and 3, an oxo group at position 9 and a nonyl group at position 8. Isolated from the culture broth of the fungus Talaromyces trachyspermus, it exhibits inhibitory activity against the enzyme heparanase. | trachyspic acid |
| trapoxin a | A homodetic cyclic tetrapeptide constructed from L-phenylalanyl (x2), D-pipecolinyl and L-2-amino-8-oxo-9,10-epoxydecanoyl residues. | trapoxin A |
| urethane | A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages. | urethane |
| veratryl alcohol | A member of the class of benzyl alcohols that is benzyl alcohol in which the hydrogens at positions 3 and 4 of the phenyl group are substituted by methoxy groups. | (3,4-dimethoxyphenyl)methanol |
| yw 3548 | A terpene lactone that is obtained from Codinea simplex and acts as an inhibitor of glycerophosphoinositol biosynthesis. | YW3548 |
| zaragozic acid c | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid C |
| zearalenone | A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species. | zearalenone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 8.9109 | 1 | 8 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 27.0170 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 17.2560 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 38.2897 | 2 | 4 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 170.6734 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 30.9485 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 25.9979 | 1 | 10 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.7943 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 31.3809 | 12 | 49 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 49.7601 | 2 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 20.5526 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.7346 | 4 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 16.5935 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 16.8089 | 2 | 6 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 16.5935 | 1 | 1 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 4.7755 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 3.9860 | 2 | 7 |
| BRCA1 | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 19.8468 | 1 | 3 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 58.8760 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 58.8760 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 25.8870 | 3 | 12 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 18.5412 | 2 | 4 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 17.1346 | 1 | 9 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 11.9737 | 3 | 8 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 25.3643 | 2 | 6 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 35.7168 | 2 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 33.0488 | 1 | 3 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 15.2864 | 2 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 16.2595 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 13.2247 | 4 | 13 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 11.1609 | 2 | 5 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 2.6054 | 2 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 15.2864 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 58.7704 | 2 | 10 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 0.3604 | 2 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 26.2000 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 13.2036 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 7.4378 | 2 | 7 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.7275 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 14.2184 | 1 | 6 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 4.1092 | 1 | 1 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 16.4816 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 19.8928 | 3 | 4 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 10.1505 | 3 | 4 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 27.0498 | 1 | 5 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 23.2925 | 2 | 5 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 21.1923 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 42.3866 | 1 | 8 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 20.0910 | 1 | 8 |
| endonuclease IV | Escherichia coli | Potency | 22.5358 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 2.8184 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 2.8184 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 26.4288 | 12 | 69 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 20.9899 | 2 | 4 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 19.1961 | 9 | 31 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 3.6500 | 1 | 13 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 22.0858 | 3 | 3 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 26.3340 | 3 | 7 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 40.3553 | 2 | 6 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 63.0957 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 6.5578 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 11.9519 | 2 | 12 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 22.9127 | 3 | 19 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 2.2387 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 17.3782 | 2 | 8 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 20.4985 | 5 | 15 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 31.6005 | 2 | 7 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 16.1272 | 2 | 4 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 18.1554 | 2 | 4 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 32.0526 | 2 | 7 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 5.6294 | 2 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 17.2337 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 22.5599 | 1 | 3 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 28.9240 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 82.1801 | 1 | 4 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 30.6694 | 1 | 2 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 2.4181 | 2 | 3 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 11.0956 | 3 | 4 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 32.4664 | 1 | 6 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 2.5788 | 2 | 4 |
| IDH1 | Homo sapiens (human) | Potency | 9.1044 | 1 | 4 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 11.6708 | 2 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 67.2676 | 1 | 2 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 8.1374 | 2 | 8 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 3.9804 | 1 | 5 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 33.9155 | 3 | 6 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 30.1383 | 3 | 4 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 3.6593 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 24.6288 | 2 | 11 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 27.3294 | 2 | 6 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 14.1096 | 1 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 45.3265 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.9244 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 8.1548 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 29.7403 | 4 | 17 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 16.4687 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 40.0651 | 1 | 5 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 58.5706 | 1 | 4 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 17.2103 | 2 | 9 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 34.4183 | 3 | 16 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 48.6078 | 1 | 2 |
| Parkin | Homo sapiens (human) | Potency | 21.5763 | 3 | 5 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 5.3576 | 2 | 3 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0026 | 1 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 32.9721 | 4 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 40.6542 | 4 | 9 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 1.2928 | 2 | 2 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 68.5705 | 1 | 7 |
| PINK1 | Homo sapiens (human) | Potency | 31.3540 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 1.1294 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 3.7842 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 48.0224 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.8626 | 2 | 10 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 31.4034 | 2 | 6 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 2.8184 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 49.5626 | 1 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 23.1824 | 2 | 12 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 35.6193 | 1 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 40.9903 | 3 | 27 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 24.2554 | 3 | 11 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 0.3604 | 2 | 2 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 25.7877 | 1 | 2 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 12.8750 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 22.1971 | 1 | 4 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 15.8489 | 1 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 31.5749 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 31.5749 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 6.1900 | 1 | 3 |
| snurportin-1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 29.8816 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 9.5486 | 1 | 10 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 7.0193 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 13.2781 | 2 | 27 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 2.0698 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 26.6743 | 2 | 9 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 28.2179 | 3 | 25 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 26.1854 | 3 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 26.6934 | 6 | 14 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 9.8400 | 1 | 3 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 1.1294 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 1.1294 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 51.0103 | 2 | 7 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 47.0958 | 2 | 6 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 21.6723 | 5 | 10 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 29.2099 | 5 | 8 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 36.8649 | 1 | 6 |
| Vpr | Human immunodeficiency virus 1 | Potency | 3.1623 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | IC50 | 0.0483 | 4 | 4 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | IC50 | 0.1340 | 9 | 9 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 188.0000 | 1 | 1 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | Homo sapiens (human) | IC50 | 115.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 0.0081 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.0046 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Oryctolagus cuniculus (rabbit) | IC50 | 100.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 0.0081 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.0046 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 0.0053 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.0006 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.2820 | 3 | 4 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.0026 | 2 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.0026 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 0.0144 | 2 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.0110 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0210 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.0110 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 0.0032 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.0015 | 1 | 1 |
| 5-lipoxygenase | Bos taurus (cattle) | IC50 | 14.0000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 1.8500 | 1 | 1 |
| 5'-nucleotidase | Mus musculus (house mouse) | IC50 | 0.0400 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 115.0000 | 1 | 1 |
| 72 kDa type IV collagenase isoform 1 preproprotein | Homo sapiens (human) | IC50 | 78.4000 | 1 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 2.4020 | 1 | 1 |
| acetyl-CoA acetyltransferase/HMG-CoA reductase | Enterococcus faecalis | IC50 | 1,265.3900 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 132.9200 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 17.0150 | 2 | 2 |
| Adenosine deaminase | Homo sapiens (human) | Ki | 7.0000 | 1 | 1 |
| Adenosine deaminase | Bos taurus (cattle) | Ki | 11.0000 | 2 | 2 |
| Adenosine receptor A1 | Bos taurus (cattle) | IC50 | 1,006,650,005.0433 | 3 | 3 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 10.0520 | 2 | 2 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 44.1668 | 4 | 6 |
| Adenosine receptor A1 | Bos taurus (cattle) | Ki | 4.1143 | 7 | 7 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | Ki | 57.0909 | 7 | 11 |
| Adenosine receptor A1 | Gallus gallus (chicken) | Ki | 6.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 19.7278 | 28 | 33 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 22.1301 | 45 | 73 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 16.2395 | 1 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2a | Cavia porcellus (domestic guinea pig) | Ki | 35.6000 | 3 | 5 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 13.7803 | 38 | 48 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 84.7183 | 34 | 63 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 18.4318 | 29 | 38 |
| Adenosine receptor A2b | Mus musculus (house mouse) | Ki | 23.0000 | 1 | 1 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 24.4420 | 20 | 44 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 47.4067 | 28 | 32 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 49.9100 | 9 | 15 |
| Aldehyde oxidase 1 | Cavia porcellus (domestic guinea pig) | Ki | 4.5300 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 0.2000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 40.6500 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Ki | 82.0000 | 1 | 1 |
| Alpha-(1,3)-fucosyltransferase 7 | Homo sapiens (human) | IC50 | 115.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 15.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.6800 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.6300 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.2890 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.1320 | 1 | 1 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | IC50 | 0.0020 | 1 | 1 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | Ki | 0.0001 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 17.8067 | 3 | 3 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 0.2600 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 1,850.5800 | 4 | 4 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 100.0000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 200.0000 | 2 | 2 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 0.2600 | 1 | 1 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 5,000.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 53.2000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 1,000.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 107.7500 | 2 | 2 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 558.7500 | 2 | 2 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 2.4800 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 2.6333 | 3 | 3 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 5.8250 | 1 | 2 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 3.9000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 20.7000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 366.1429 | 3 | 7 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 14,000.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 340.4000 | 5 | 5 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 300.5000 | 4 | 4 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Ki | 2.0976 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 0.6000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 9.7000 | 3 | 3 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 9.7000 | 3 | 3 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 9.7000 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | IC50 | 608.8000 | 4 | 5 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 527.7500 | 4 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | IC50 | 637.0000 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 637.0000 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 1.0600 | 1 | 2 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 0.9900 | 1 | 2 |
| Carbonic anhydrase | Mycobacterium tuberculosis H37Rv | Ki | 11.7500 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 28,500.0000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 166.6743 | 5 | 7 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 8.5167 | 3 | 3 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 4.2400 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 10.3000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 37.9550 | 2 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 20,666.6667 | 2 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 68.3257 | 5 | 7 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 9.0800 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 7.5900 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 12.7000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 7.0600 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 27.7033 | 3 | 3 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 31.9233 | 3 | 3 |
| Casein kinase 1, delta tv1 | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 6.2800 | 4 | 4 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Casein kinase II subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0400 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 8.3600 | 3 | 3 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 8.3600 | 3 | 3 |
| Casein kinase II subunit beta | Rattus norvegicus (Norway rat) | IC50 | 0.0400 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 210.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| Chain A, ADENOSINE DEAMINASE | Mus musculus (house mouse) | Ki | 9.0000 | 1 | 1 |
| Chain A, Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Chain A, Chitinase | Clonostachys rosea | Ki | 19,700.0000 | 1 | 1 |
| Chain A, Glycogen Phosphorylase | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 1 |
| Chain A, Penicillin Amidohydrolase | Escherichia coli | Ki | 107.0000 | 1 | 7 |
| Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta)) | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 5,000.0000 | 1 | 6 |
| Chain A, Pyridoxal Kinase | Homo sapiens (human) | Ki | 50.0000 | 1 | 2 |
| Chain B, Penicillin Amidohydrolase | Escherichia coli | Ki | 107.0000 | 1 | 7 |
| Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 5,000.0000 | 1 | 6 |
| Chain X, Dimeric dihydrodiol dehydrogenase | Macaca fascicularis (crab-eating macaque) | IC50 | 0.9700 | 1 | 1 |
| Chitotriosidase-1 | Homo sapiens (human) | IC50 | 681.5000 | 1 | 4 |
| Cholinesterase | Homo sapiens (human) | IC50 | 125.0000 | 2 | 2 |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | Homo sapiens (human) | IC50 | 115.0000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 61.0000 | 1 | 3 |
| Cruzipain | Trypanosoma cruzi | IC50 | 142.0000 | 2 | 2 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 3.3900 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 5.2120 | 5 | 5 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 5.2120 | 5 | 5 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 1.0900 | 1 | 1 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.2800 | 4 | 4 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 0.2800 | 4 | 4 |
| Cysteine protease ATG4B | Homo sapiens (human) | IC50 | 4.2500 | 2 | 2 |
| Cytidine deaminase | Mus musculus (house mouse) | Ki | 10.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 58.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 7.6320 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 4.7700 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 1.9500 | 1 | 1 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 100.0000 | 2 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 5.9010 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 2.9500 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 0.5520 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.1840 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.5670 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.1930 | 1 | 1 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.0006 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 3.3500 | 1 | 2 |
| DNA damage-inducible transcript 3 protein | Mus musculus (house mouse) | IC50 | 9.6900 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| DNA polymerase alpha catalytic subunit | Homo sapiens (human) | IC50 | 5.1500 | 6 | 6 |
| DNA polymerase beta | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| DNA polymerase beta | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain 17 | IC50 | 0.5000 | 1 | 1 |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain KOS | IC50 | 0.4380 | 1 | 1 |
| DNA polymerase catalytic subunit | Human herpesvirus 3 strain Dumas | IC50 | 1.6000 | 1 | 2 |
| DNA polymerase catalytic subunit | Human herpesvirus 5 strain AD169 | IC50 | 0.4435 | 2 | 2 |
| DNA polymerase catalytic subunit | Human herpesvirus 6 (strain Uganda-1102) | IC50 | 0.4000 | 1 | 1 |
| DNA polymerase delta catalytic subunit | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| DNA polymerase eta | Homo sapiens (human) | IC50 | 0.0620 | 1 | 1 |
| DNA polymerase iota | Homo sapiens (human) | IC50 | 0.0620 | 1 | 1 |
| DNA polymerase lambda | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| DNA polymerase subunit gamma-1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| DNA primase | Mycobacterium tuberculosis CDC1551 | IC50 | 100.0000 | 1 | 1 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 1.1050 | 2 | 2 |
| dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 39.5000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | Mus musculus (house mouse) | IC50 | 0.5000 | 1 | 1 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Endochitinase B1 | Aspergillus fumigatus | IC50 | 681.5000 | 1 | 4 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 1.8300 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.6900 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 47.6714 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 47.6714 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 51.5550 | 2 | 2 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| G-protein coupled receptor 35 isoform a | Homo sapiens (human) | IC50 | 3.0557 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 1.0900 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.5025 | 10 | 13 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.5439 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 0.8120 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 0.8189 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 0.0085 | 2 | 2 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 31.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 34.3833 | 3 | 3 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 22.8000 | 1 | 1 |
| Glutathione S-transferase | Plasmodium falciparum 3D7 | IC50 | 74.4000 | 1 | 1 |
| Glutathione S-transferase Mu 1 | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 63.5500 | 2 | 2 |
| Glycogen phosphorylase, liver form | Rattus norvegicus (Norway rat) | IC50 | 648.0000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 159.1933 | 13 | 15 |
| Glycogen phosphorylase, muscle form | Rattus norvegicus (Norway rat) | IC50 | 182.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 6.4877 | 3 | 3 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Guanine deaminase | Homo sapiens (human) | Ki | 10.2000 | 1 | 1 |
| heat shock 70kDa protein 1A | Homo sapiens (human) | IC50 | 66.9200 | 3 | 3 |
| heat shock cognate 71 kDa protein isoform 1 | Homo sapiens (human) | IC50 | 99.6000 | 2 | 2 |
| heat shock cognate 71 kDa protein isoform 2 | Homo sapiens (human) | IC50 | 99.6000 | 2 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 2.4020 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 40.1933 | 3 | 3 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 3.7730 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 90.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 90.0600 | 2 | 2 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 1.9800 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | IC50 | 0.3400 | 1 | 1 |
| Insulin receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1190 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 16.7750 | 2 | 2 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 5.1000 | 2 | 2 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Isocitrate lyase 1 | Mycobacterium tuberculosis CDC1551 | IC50 | 29.4000 | 1 | 1 |
| likely tRNA 2'-phosphotransferase | Candida albicans SC5314 | IC50 | 0.2913 | 2 | 2 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 138.0800 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 4.7700 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 1.9500 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0430 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0380 | 1 | 1 |
| Matrilysin | Homo sapiens (human) | IC50 | 115.0000 | 1 | 1 |
| Mcl-1 | Homo sapiens (human) | IC50 | 19.5726 | 2 | 3 |
| Methionine aminopeptidase | Escherichia coli K-12 | IC50 | 100.0000 | 1 | 1 |
| Methionine aminopeptidase 1 | Saccharomyces cerevisiae S288C | IC50 | 100.0000 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 0.0082 | 4 | 4 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | IC50 | 0.0330 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 8 | Homo sapiens (human) | IC50 | 2.3700 | 1 | 1 |
| mothers against decapentaplegic homolog 3 isoform 1 | Homo sapiens (human) | IC50 | 0.1420 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 4 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 37.6667 | 3 | 3 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 30.6000 | 1 | 1 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 16.7550 | 2 | 2 |
| Nuclear receptor subfamily 2 group C member 2 | Homo sapiens (human) | IC50 | 0.0300 | 1 | 1 |
| Nucleophosmin | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Oxoeicosanoid receptor 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 2 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | IC50 | 18.6000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3,267.0000 | 1 | 2 |
| Phosphodiesterase | Bos taurus (cattle) | IC50 | 250.3333 | 6 | 6 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Phosphodiesterase | Bos taurus (cattle) | Ki | 77.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens (human) | IC50 | 1.7200 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Potassium channel subfamily K member 9 | Homo sapiens (human) | IC50 | 159.0000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 1,400.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 223.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 13.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 0.1190 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 17.9000 | 2 | 2 |
| Protein farnesyltransferase subunit beta | Rattus norvegicus (Norway rat) | IC50 | 1.4990 | 2 | 2 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 1.4990 | 2 | 2 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 9.0067 | 3 | 3 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 8.5500 | 3 | 3 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 15.4000 | 2 | 2 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Protein kinase C-like 1 | Candida albicans | IC50 | 0.0440 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 9.1000 | 4 | 4 |
| PSMD14 protein | Homo sapiens (human) | IC50 | 2.9400 | 1 | 1 |
| PTK2B protein tyrosine kinase 2 beta | Homo sapiens (human) | IC50 | 6.9220 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 51.6700 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 3.5400 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Renin | Homo sapiens (human) | IC50 | 0.9800 | 1 | 1 |
| Renin | Homo sapiens (human) | Ki | 6.5500 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 68.8933 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 100.0000 | 1 | 2 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 7.6320 | 1 | 1 |
| RNA-directed RNA polymerase | | IC50 | 47.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 51.0000 | 1 | 1 |
| Sentrin-specific protease 1 | Homo sapiens (human) | IC50 | 4.9450 | 2 | 2 |
| Serine palmitoyltransferase 2 | Homo sapiens (human) | IC50 | 0.0001 | 1 | 1 |
| Serine-protein kinase ATM | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | IC50 | 1,100.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 1.7600 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 54.9000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 4.2000 | 2 | 2 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 39.5200 | 2 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | IC50 | 2.9700 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 7.9000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 190.5460 | 1 | 1 |
| Solute carrier family 22 member 4 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 3,235.9400 | 1 | 1 |
| sphingosine 1-phosphate receptor 1 | Homo sapiens (human) | IC50 | 17.6200 | 1 | 1 |
| Sphingosine-1-phosphate receptor 4 | Homo sapiens (human) | IC50 | 0.6480 | 1 | 1 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 2.0000 | 1 | 1 |
| Squalene synthase | Rattus norvegicus (Norway rat) | IC50 | 0.0043 | 2 | 3 |
| Succinate-semialdehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 166.0000 | 1 | 1 |
| Tat | Human immunodeficiency virus 1 | IC50 | 1.6690 | 1 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 1,708.9200 | 1 | 1 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | IC50 | 0.0300 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | Ki | 14.0000 | 1 | 1 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | IC50 | 0.0575 | 2 | 2 |
| Tissue alpha-L-fucosidase | Homo sapiens (human) | IC50 | 0.2300 | 3 | 3 |
| Tissue alpha-L-fucosidase | Rattus norvegicus (Norway rat) | IC50 | 0.3400 | 1 | 1 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | Ki | 0.0026 | 3 | 3 |
| Tissue alpha-L-fucosidase | Homo sapiens (human) | Ki | 0.0450 | 2 | 2 |
| Tissue factor | Homo sapiens (human) | IC50 | 61.0000 | 1 | 3 |
| TPA: prothrombin | Bos taurus (cattle) | IC50 | 4.8100 | 1 | 1 |
| Translin-associated protein X | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| Translocator protein | Rattus norvegicus (Norway rat) | IC50 | 1.6218 | 1 | 1 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 2 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Tyrosinase | Mus musculus (house mouse) | IC50 | 500.0000 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Rattus norvegicus (Norway rat) | IC50 | 3.5000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Rattus norvegicus (Norway rat) | IC50 | 7.5000 | 1 | 1 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| unnamed protein product | Aspergillus oryzae RIB40 | IC50 | 52.7195 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 6.2450 | 2 | 2 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 1.5400 | 1 | 1 |
| Vif | Human immunodeficiency virus 1 | IC50 | 0.4500 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 841.3000 | 2 | 2 |
| XBP1 | Homo sapiens (human) | IC50 | 6.3400 | 1 | 1 |