Page last updated: 2024-08-05 12:26:03

ergostanoid

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ChEBI ID: 50403

Members (16)

MemberDefinitionRole
2,3-dihydro-3beta-methoxy withaferin AA withanolide that is 2,3-dihydrowithaferin A substituted by a beta-methoxy group at position 3. It has been isolated from the aerial parts of Physalis longifolia.2,3-dihydro-3beta-methoxy withaferin A
2,3-dihydro-3beta-O-sulfate withaferin AA withanolide that is 2,3-dihydrowithaferin A substituted by a sulfoxy group at position 3. Isolated from Physalis longifolia, it exhibits antineoplastic activity.2,3-dihydro-3beta-O-sulfate withaferin A
2,3-dihydrowithaferin AA withanolide that is the 2,3-dihydro derivative of withaferin A. It has been isolated from the aerial parts of Physalis longifolia.2,3-dihydrowithaferin A
22,23-dihydroergosterolA phytosterol consiting of ergostane having double bonds at the 5,6- and 7,8-positions as well as a 3beta-hydroxy group.ergosta-5,7-dien-3beta-ol
4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity.zhankuic acid A
antcin aantcin A
brassicasterolAn 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil.brassicasterol
cerevisterolAn ergostanoid that is (22E)-ergosta-7,22-diene substituted by hydroxy groups at positions 3, 5 and 6 (the 3beta,5alpha,6beta stereoisomer). It has been isolated from the fungus, Xylaria species.cerevisterol
dehydroergosterolA phytosterol consiting of ergostane having double bonds at the 5,6-, 7,8- 9,11- and 22,23-positions as well as a 3beta-hydroxy group.dehydroergosterol
ergosta-4,6,8(14),22-tetraen-3-oneAn ergostanoid that is (22E)-ergosta-4,6,8(14),22-tetraene substituted by an oxo group at position 3. It has been isolated from the mycelia of Cordyceps sinensis.ergosta-4,6,8(14),22-tetraen-3-one
ergosterolA phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group.ergosterol
ergosterol-5,8-peroxideAn ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities.ergosterol peroxide
halistanol trisulfateHalistanol sulfate
tubocapsanolide aA withanolide that is 5beta,6beta:16alpha,17alpha-diepoxywitha-2,24-dienolide substituted by a hydroxy group at position 4 and an oxo group at position 1. Isolated from Tubocapsicum anomalum, it exhibits cytotoxic activity.tubocapsanolide A
withaferin aA withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.withaferin A
withanolide dA withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 22 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Tubocapsicum anomalum and Withania somnifera, it exhibits cytotoxic activity.withanolide D

Research

Studies (3,439)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990495 (14.39)18.7374
1990's336 (9.77)18.2507
2000's809 (23.52)29.6817
2010's1,317 (38.30)24.3611
2020's482 (14.02)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials25 (0.63%)5.53%
Reviews204 (5.17%)6.00%
Case Studies8 (0.20%)4.05%
Observational0 (0.00%)0.25%
Other3,709 (93.99%)84.16%