Cryoglobulinemia

A condition characterized by the presence of abnormal quantities of CRYOGLOBULINS in the blood. Upon cold exposure, these abnormal proteins precipitate into the microvasculature leading to restricted blood flow in the exposed areas.

Synonym
Cryoglobulinemia

Excerpt	Reference
"Cryoglobulinemia is seen in a minority of patients with plasma cell dyscrasias and can be of clinical relevance if intravascular gelling or precipitate formation occurs at low temperatures."	( Anselstetter, V; Binder, T; Galle, J; Heimpel, H; Schoengen, A; Schreiner, T; Weber, L, 1989)
"Essential mixed cryoglobulinemia is a systemic disorder in which cutaneous vasculitis and frequently glomerulonephritis are associated with cryoprecipitable serum immune complexes."	( Curd, JG; Lee, TC; Miller, WE; Piro, LD; Saven, A, 1996)
"Mixed cryoglobulinemia is a well-known complication after hepatitis C virus (HCV) infection."	( Ashur, Y; Ilan, Y; Safadi, R; Shouval, D; Tur-Kaspa, R, 1996)
"Mixed cryoglobulinemia is common in patients with HIV-1 infection."	( Dimitrakopoulos, AN; Hatzakis, A; Kordossis, T; Moutsopoulos, HM, 1999)
"Type II cryoglobulinemia is sometimes observed in patients with HCV infection."	( Nishikawa, T; Suzuki, H; Takei, T; Tsuji, H, 2000)
"Mixed cryoglobulinemia is characterized by a wide spectrum of manifestations that may vary from mild symptoms (such as purpura, arthralgias, and Raynaud phenomenon) to life-threatening conditions (such as acute abdomen, hyperviscosity syndrome, and renal involvement)."	( Baldini, C; Bombardieri, S; Della Rossa, A; Tavoni, A, 2002)
"Renal cryoglobulinemia is an uncommon illness of diverse etiologies and clinical presentations."	( Bastacky, S; Beddhu, S; Johnson, JP, 2002)
"Mixed cryoglobulinemia is currently treated with steroids, low-antigen content diet, immunosuppressors, plasma exchange, and antiviral therapy, namely, alpha -interferon alone or, more recently, in association with ribavirin."	( Cacciatore, P; Capani, F; Chincoli, C; Cosentino, L; D'Amico, E; di Pasqua, G; Palazzi, C; Pennese, E; Riario-Sforza, G, 2005)
"Type II cryoglobulinemia is a nonfatal disease most frequently associated with hepatitis C."	( Bryce, AH; Dispenzieri, A; Gertz, MA; Kyle, RA, 2006)
"Mixed cryoglobulinemias are associated with hepatitis C virus infection in over 80% of cases."	( Jeker, R; Tini, GM; Wüscher, V, 2007)
"Cryoglobulinemia are immune complexes that may induce systemic cryoglobulinemic vasculitis."	( Cacoub, P; Saadoun, D; Sène, D, 2008)
"Hepatitis C-related cryoglobulinemia is a rare condition that usually presents with nonspecific symptoms."	( Dalhoff, K; Heyer, P; Rupp, J; Schaaf, B; Witte, L, 2008)
"Cryoglobulinemia is frequent after liver transplant and is symptomatic in approximately 20% of all patients."	( Blancher, A; Boulestin, A; Durand, D; Esposito, L; Garrouste, C; Kamar, N; Lavayssiere, L; Rostaing, L, 2008)
"Cryoglobulinemia is a systemic immune complex-mediated vasculitis that can have significant morbidity and mortality."	( Fogo, AB; Schulman, G; Wallace, E, 2012)
"Mixed cryoglobulinemia is commonly related to chronic HCV infection, and renal complications occur frequently."	( Calayoglu, R; Ensari, A; Erbay, B; Kiremitci, S, 2012)
"HCV-related mixed cryoglobulinemia is uncommon in developed countries and this clearly hampers randomized controlled clinical trials aimed to evaluate efficacy and safety of antiviral therapy in non-immunosuppressed individuals."	( Dixit, V; Fabrizi, F; Messa, P, 2013)
"Heat-insoluble cryoglobulinemia is rare, and its pathogenesis and comorbidities remain poorly understood."	( Du, YJ; Li, X; Lu, RH; Wu, H; Xu, Y; Yu, JY; Zhang, L; Zou, HB, 2013)
"Mixed cryoglobulinemia is occasionally seen in patients with hepatitis B virus (HBV) infection."	( Akimoto, T; Iwazu, K; Iwazu, Y; Komada, T; Kusano, E; Morishita, Y; Muto, S; Numata, A; Okuda, K; Saito, O; Sugase, T; Takemoto, F; Takeshima, E; Yamazaki, T; Yoshizawa, H, 2014)
"Type 1 cryoglobulinemia is composed of a single monoclonal immunoglobulin and is associated with renal involvement in up to 40% of cases."	( Alyanakian, MA; Bridoux, F; Javaugue, V; Joly, D; Knebelmann, B; Nochy, D; Plasse, F; Rabant, M; Zaidan, M, 2016)
"Mixed cryoglobulinemia is strongly associated with hepatitis C virus (HCV) infection and ranges from being asymptomatic to causing life-threatening vasculitis."	( Almarzooqi, S; Emery, JS; Feld, JJ; Janssen, HLA; Kowgier, M; Kuczynski, M; La, D; Shah, H; Wong, D, 2017)
"Cryoglobulinemia is a manifestation of hepatitis C virus (HCV) infection."	( Chowdhury, R; Tsen, A, 2017)
"Mixed cryoglobulinemia is frequently secondary to hepatitis C virus infection."	( Bana E Costa, T; Carvalho, L; Chagas, C; Túlio, M, 2017)
"Type I cryoglobulinemia is associated with B cell proliferative diseases, whereas essential mixed cryoglobulinemia is classically associated with infections, malignancy, and autoimmune diseases, but may be idiopathic."	( Biro, A; Rozman, Z; Tanay, A; Tocut, M; Winder, A; Zandman-Goddard, G, 2019)

Excerpt	Reference
"Cryoglobulinemia has been reported in several chronic infectious and autoimmune diseases, and in patients with HIV-1 infection."	( Dafni, U; Kontos, A; Kordossis, T; Moutsopoulos, HM; Sipsas, NV, 2001)
"Cryoglobulinemia has been described in infectious diseases, but in only three patients with brucellosis."	( Hermida Lazcano, I; Sáez Méndez, L; Solera Santos, J, 2005)

Excerpt	Reference
"Twenty-seven patients were treated for cryoglobulinemia."	( Siami, FS; Siami, GA, 1998)
"Splenectomy is not widely accepted as a treatment for cryoglobulinemia."	( Chayama, K; Hara, M; Hara, S; Katori, H; Kitamura, A; Matsushita, Y; Nagahama, K; Tagami, T; Takemoto, F; Ubara, Y; Yamada, A; Yokota, M, 2000)
"Successful treatment of cryoglobulinemia with IFN/RBV in recipients of combined liver/kidney transplant has not been previously reported."	( Colledan, M; Montalbano, M; Pasulo, L; Remuzzi, G; Sonzogni, A; Strazzabosco, M, 2007)
"The current treatment for cryoglobulinemia, including chlorambucil, steroids, plasmapheresis, and rituximab, is lacking in terms of efficacy, safety, and relapse rates."	( Fogo, AB; Schulman, G; Wallace, E, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	95 (17.09)	23.3326
1990's	94 (16.91)	12.5806
2000's	173 (31.12)	18.1394
2010's	175 (31.47)	28.8240
2020's	19 (3.42)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
adenine	low	4	0
carbamates	low	9	0
chlorine	low	1	0
formaldehyde	low	1	0
glycine	low	1	0
dalteparin	low	1	0
purine	low	1	0
pyridoxine	low	1	0
uracil	low	2	0
urea	low	3	0
mercaptoethanol	low	1	0
hydroxyindoleacetic acid	low	1	0
amantadine	low	1	0
azathioprine	medium	8	1
carbamazepine	low	2	0
chlorambucil	low	7	0
chloroquine	low	4	0
dapsone	low	1	0
deferoxamine	low	1	0
furosemide	low	1	0
gabapentin	low	1	0
guanidine	low	1	0
hydralazine	low	1	0
hydroxychloroquine	low	3	0
hydroxyurea	low	1	0
avapro	low	1	0
isoniazid	low	1	0
2-propanol	low	1	0
ketamine	low	1	0
methadone	low	1	0
methylphenidate	low	1	0
nafamostat	low	1	0
nifedipine	low	1	0
ofloxacin	low	1	0
pentoxifylline	low	2	0
sulfinpyrazone	low	1	0
thalidomide	low	10	0
ticlopidine	low	1	0
prednisolone	low	40	0
thymidine	low	1	0
penicillamine	low	3	0
trichlorfon	low	1	0
prednisone	medium	46	3
penicillin g	low	1	0
aspartic acid	low	1	0
uridine monophosphate	low	3	0
galactose	low	2	0
tyrosine	low	1	0
cysteamine	low	1	0
methylene blue	low	1	0
methionine	low	2	0
colchicine	low	6	0
valine	low	8	0
methylprednisolone	medium	25	1
penicillanic acid	low	1	0
2-naphthylamine	low	2	0
sym-trinitrobenzene	low	1	0
pyrroles	low	1	0
2-chloroadenosine	low	1	0
fluocortolone	low	1	0
pyrazines	low	4	0
testosterone enanthate	low	1	0
citrulline	low	1	0
betamethasone	low	1	0
limestone	low	1	0
eosine yellowish-(ys)	low	1	0
pyrithioxin	low	1	0
vancomycin	low	1	0
methylprednisolone hemisuccinate	low	1	0
mannose	low	1	0
cladribine	low	3	0
vidarabine	low	9	0
trolamine salicylate	medium	26	1
stanozolol	low	7	0
tetradecanoylphorbol acetate	low	1	0
fludarabine phosphate	low	1	0
4-methoxyamphetamine	low	1	0
oxcarbazepine	low	1	0
vidarabine phosphate	low	1	0
ribavirin	medium	107	14
piperacillin	low	1	0
captopril	medium	1	1
fomesafen	low	1	0
adefovir	low	2	0
clopidogrel	low	1	0
lamivudine	low	5	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	1	0
diflorasone	low	1	0
voriconazole	low	1	0
bendamustine hydrochloride	low	2	0
fibrinogen	low	36	0
mizoribine	low	3	0
bosentan anhydrous	low	1	0
imatinib mesylate	low	2	0
tazobactam	low	1	0
methotrexate	low	3	0
proline	medium	6	2
telbivudine	low	1	0
tartrazine	low	1	0
technetium tc 99m pentetate	low	1	0
organophosphonates	low	2	0
deflazacort	medium	3	1
deferasirox	low	1	0
lenalidomide	low	5	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
bortezomib	low	19	0
ritonavir	low	4	0
fibrin	low	4	0
retinol	low	1	0
cocaine	low	1	0
mycophenolic acid	low	5	0
zithromax	low	1	0
diethylstilbestrol	low	1	0
arsphenamine	low	1	0
melphalan	low	2	0
tenofovir	low	1	0
l 743,872	low	1	0
fludarabine	low	7	0
propylthiouracil	low	1	0
telaprevir	medium	3	1
2-chloro-3'-deoxyadenosine	low	1	0
chloramine-t	low	1	0
dinoprost	low	1	0
alprostadil	low	1	0
amphotericin b	low	4	0
phenylephrine hydrochloride	low	2	0
oxycodone	low	1	0
aluminum	low	1	0
heroin	low	2	0
i(3)so3-galactosylceramide	low	2	0
sq-23377	low	1	0
mocetinostat	low	7	0
losartan potassium	low	1	0
sepharose	low	1	0
acid phosphatase	low	1	0
bms-650032	low	1	0
glycoprotein e2, hepatitis c virus	low	9	0
ristocetin	low	1	0
cellulose	low	1	0
igk	low	1	0
ro13-9904	low	1	0
pci 32765	low	2	0
cardiovascular agents	low	2	0
bms-790052	low	5	0
ixazomib	low	1	0
piperidines	low	2	0
interleukin-8	low	2	0
abt-450	low	4	0
sofosbuvir	medium	16	2
natriuretic peptide, brain	low	2	0
ascorbic acid	low	1	0
tetracycline	low	1	0
salicylates	low	1	0
dicumarol	low	2	0
warfarin	low	5	0
abt-267	low	4	0
abt-333	low	2	0
transforming growth factor beta	low	2	0
ledipasvir	low	1	0
gs-5816	low	1	0
agar	low	1	0
cyclin d1	low	1	0
cyclosporine	low	1	0
entecavir	low	6	0
guanine	low	6	0
neopterin	low	2	0
rifampin	low	2	0
ganciclovir	low	1	0
allopurinol	low	1	0
valganciclovir	low	1	0
defibrotide	low	1	0
eye	low	3	0
concanavalin a	low	2	0
metallothionein	low	1	0

Protein Targets (1,610)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
Chain A, Beta-lactamase	7	0	0	7
glp-1 receptor, partial	10	0	0	10
TDP1 protein	43	0	0	43
Smad3	14	0	0	14
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
NPYLR7B	0	0	1	1
67.9K protein	13	0	0	13
IDH1	22	0	0	22
cellular tumor antigen p53 isoform a	9	0	0	9
vasopressin V1b receptor	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	18	0	0	18
glycogen synthase kinase-3 beta isoform 1	0	0	5	5
mitogen-activated protein kinase 1	9	0	0	9
flap endonuclease 1	8	0	0	8
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
DNA polymerase iota isoform a (long)	13	0	0	13
urokinase-type plasminogen activator precursor	14	0	0	14
plasminogen precursor	14	0	0	14
urokinase plasminogen activator surface receptor precursor	14	0	0	14
geminin	41	0	0	41
survival motor neuron protein isoform d	18	0	0	18
relaxin receptor 1 isoform 1	3	0	0	3
high affinity choline transporter 1 isoform a	0	2	0	2
relaxin receptor 2 isoform 1	1	0	0	1
lamin isoform A-delta10	43	0	0	43
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Renin	0	2	0	2
Integrin beta-3	7	1	0	8
Heat shock protein HSP 90-alpha	0	2	1	3
Integrin alpha-IIb	7	1	0	8
Adenosine receptor A3	0	8	1	9
Endoplasmin	0	1	1	2
Adenosine receptor A1	0	2	0	4
Adenosine receptor A1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	5	2	8
Adenosine receptor A2b	0	2	1	4
Adenosine receptor A2b	0	2	0	4
Adenosine receptor A1	0	6	0	7
Adenosine receptor A2a	0	3	0	6
Adenosine receptor A2a	0	0	1	1
Adenosine receptor A1	0	1	1	2
Adenosine deaminase	0	2	0	5
Adenylate cyclase type 5	0	1	0	1
Ataxin-2	20	0	0	20
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Luciferase	18	0	0	18
thioredoxin reductase	24	0	0	24
ClpP	3	0	0	3
pregnane X receptor	7	0	0	7
RAR-related orphan receptor gamma	31	0	0	31
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
AR protein	49	0	0	49
apical membrane antigen 1, AMA1	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
estrogen receptor 2 (ER beta)	18	0	0	18
nuclear receptor subfamily 1, group I, member 3	25	0	0	25
regulator of G-protein signaling 4	12	0	0	12
glucocorticoid receptor [Homo sapiens]	35	0	0	35
retinoic acid nuclear receptor alpha variant 1	32	0	0	32
estrogen-related nuclear receptor alpha	39	0	0	39
pregnane X nuclear receptor	35	0	0	35
estrogen nuclear receptor alpha	53	0	0	53
aryl hydrocarbon receptor	15	0	0	15
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	26	0	0	26
thyroid hormone receptor beta isoform 2	31	0	0	31
nuclear factor erythroid 2-related factor 2 isoform 1	39	0	0	39
cytochrome P450 3A4 isoform 1	22	0	0	22
Gamma-aminobutyric acid receptor subunit pi	22	3	0	25
Neutrophil cytosol factor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	22	3	0	25
Gamma-aminobutyric acid receptor subunit delta	22	3	0	25
Gamma-aminobutyric acid receptor subunit gamma-2	22	3	1	26
Gamma-aminobutyric acid receptor subunit alpha-5	22	3	0	25
Gamma-aminobutyric acid receptor subunit alpha-3	22	3	0	25
Gamma-aminobutyric acid receptor subunit gamma-1	22	3	0	25
Gamma-aminobutyric acid receptor subunit alpha-2	22	3	0	25
Gamma-aminobutyric acid receptor subunit alpha-4	22	3	0	25
Gamma-aminobutyric acid receptor subunit gamma-3	22	3	0	25
Gamma-aminobutyric acid receptor subunit alpha-6	22	3	0	25
Nuclear receptor ROR-gamma	13	0	0	13
Gamma-aminobutyric acid receptor subunit alpha-1	22	3	1	26
Gamma-aminobutyric acid receptor subunit beta-3	22	3	0	25
Guanine nucleotide-binding protein G	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	22	3	1	26
GABA theta subunit	22	3	0	25
Gamma-aminobutyric acid receptor subunit epsilon	22	3	0	25
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
GLI family zinc finger 3	33	0	0	33
retinoid X nuclear receptor alpha	27	0	0	27
peroxisome proliferator-activated receptor delta	26	0	0	26
activating transcription factor 6	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	16	0	0	16
Histone H2A.x	17	0	0	17
thyroid hormone receptor beta isoform a	9	0	0	9
heat shock protein beta-1	15	0	0	15
Voltage-dependent calcium channel gamma-2 subunit	20	0	0	20
Glutamate receptor 2	20	1	0	21
5-hydroxytryptamine receptor 2C	0	5	1	7
5-hydroxytryptamine receptor 2A	0	7	1	8
5-hydroxytryptamine receptor 1A	0	4	1	5
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	4	1	5
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	8	1	9
Sodium-dependent serotonin transporter	0	5	0	6
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
Nonstructural protein 5A	0	2	4	6
Genome polyprotein	0	0	1	1
Genome polyprotein	0	0	1	1
Spike glycoprotein	20	1	3	24
RNA-directed RNA polymerase	0	1	3	5
Protein cereblon	0	10	2	15
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Solute carrier family 22 member 6	0	2	0	3
Phosphoribosyl pyrophosphate synthase-associated protein 2	0	1	0	2
Adenylate kinase isoenzyme 1	0	0	0	2
Adenylate kinase 2, mitochondrial	0	0	1	3
Capsid protein	0	1	5	6
Solute carrier family 22 member 6	0	1	0	7
Solute carrier family 22 member 8	0	2	0	7
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	35	0	0	35
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Bile salt export pump	0	60	0	60
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	13	0	0	13
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	16	0	0	16
interleukin 8	12	0	0	12
thyroid stimulating hormone receptor	21	0	0	21
progesterone receptor	23	0	0	23
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
Bloom syndrome protein isoform 1	15	0	0	15
transcriptional regulator ERG isoform 3	4	0	0	4
ras-related protein Rab-9A	3	0	0	3
ATP-binding cassette sub-family C member 3	0	44	0	44
Multidrug resistance-associated protein 4	0	44	0	46
Polyphenol oxidase 2	0	3	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	26	0	0	26
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	2	2
Canalicular multispecific organic anion transporter 1	0	41	0	41
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	2
peroxisome proliferator activated receptor gamma	28	0	0	28
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	4	2	6
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	2	0	5
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
acetylcholinesterase	14	0	0	14
NFKB1 protein, partial	7	0	0	7
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
EWS/FLI fusion protein	33	0	0	33
putative alpha-glucosidase	1	0	0	1
peripheral myelin protein 22	17	0	0	17
histone acetyltransferase KAT2A isoform 1	11	0	0	11
Solute carrier family 22 member 2	0	2	0	4
Solute carrier family 22 member 1	0	3	0	7
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 1	0	8	1	10
Glutamate receptor ionotropic, NMDA 2A	0	7	1	9
Glutamate receptor ionotropic, NMDA 2B	0	7	1	9
Glutamate receptor ionotropic, NMDA 2C	0	7	1	9
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	7	1	9
Solute carrier family 22 member 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	7	1	9
Multidrug and toxin extrusion protein 1	0	5	0	5
Solute carrier family 22 member 2	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	7	1	9
ATP-dependent phosphofructokinase	12	0	0	12
Chain A, Ferritin light chain	11	0	0	11
acid sphingomyelinase	2	0	0	2
G	18	0	0	18
cytochrome P450 2D6	12	0	0	12
chromobox protein homolog 1	22	0	0	22
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	12	0	0	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Potassium channel subfamily K member 2	0	1	2	3
Interferon beta	29	0	0	29
HLA class I histocompatibility antigen, B alpha chain	18	0	0	18
ATP-dependent translocase ABCB1	0	5	0	6
Alpha-2A adrenergic receptor	0	9	0	9
Alpha-2C adrenergic receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	5	0	5
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 6	0	5	0	5
Sodium-dependent dopamine transporter	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	11
Potassium channel subfamily K member 2	0	2	0	2
Inositol hexakisphosphate kinase 1	18	0	0	18
cytochrome P450 2C9, partial	18	0	0	18
Chain A, Cruzipain	5	0	0	5
phosphopantetheinyl transferase	16	0	0	16
GLS protein	14	0	0	14
farnesoid X nuclear receptor	22	0	0	22
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
tumor necrosis factor	2	0	0	2
vitamin D3 receptor isoform VDRA	17	0	0	17
Cytochrome P450 1A2	0	8	0	9
Cytochrome P450 3A4	0	15	0	19
Cytochrome P450 2D6	0	11	0	12
Cytochrome P450 2C9	0	16	1	19
Cytochrome P450 2C19	0	11	0	12
Potassium voltage-gated channel subfamily H member 2	0	18	0	18
Aurora kinase B	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	0	7
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	7	0	0	7
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	6	1	7
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	10	0	0	10
arylsulfatase A	10	0	0	10
cytochrome P450 2C19 precursor	6	0	0	6
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	7	0	10
Carbonic anhydrase 2	0	8	1	13
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase 4	0	0	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
Thromboxane A2 receptor	0	1	1	3
Endothelin-1 receptor	0	3	0	3
Type-1B angiotensin II receptor	0	3	0	3
Type-1 angiotensin II receptor	0	2	0	3
Type-2 angiotensin II receptor	0	1	0	1
Sodium/bile acid cotransporter	0	5	0	5
Leukotriene B4 receptor 2	0	1	1	3
ATAD5 protein, partial	10	0	0	10
Fumarate hydratase	15	0	0	15
Microtubule-associated protein tau	16	0	0	16
polyprotein	15	0	0	15
P53	1	0	0	1
thyroid stimulating hormone receptor	10	0	0	10
peripheral myelin protein 22 isoform 1	9	0	0	9
hemoglobin subunit beta	1	0	0	1
M-phase phosphoprotein 8	6	0	0	6
muscleblind-like protein 1 isoform 1	10	0	0	10
muscarinic acetylcholine receptor M1	9	0	0	9
Bile salt export pump	0	14	0	14
Protein-arginine deiminase type-4	0	4	0	4
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	12	2	19
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Genome polyprotein	0	1	0	1
Genome polyprotein	0	0	1	1
Non-structural protein 4A	0	1	0	1
PPM1D protein	12	0	0	12
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	2	0	2
caspase 7, apoptosis-related cysteine protease	5	0	0	5
caspase-3	5	0	0	5
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	2	0	2
Histone deacetylase 3	0	4	0	4
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	3	0	5
Prothrombin	0	4	0	5
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	2	0	3
Cathepsin B	0	2	0	2
Neutrophil elastase	0	2	0	3
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	2	0	3
Carbonic anhydrase 4	0	4	0	6
Carbonic anhydrase 6	0	3	0	5
Chymase	0	2	0	2
Proteasome subunit alpha type-1	0	2	0	2
Proteasome subunit alpha type-2	0	2	0	2
Proteasome subunit alpha type-3	0	2	0	2
Proteasome subunit alpha type-4	0	2	0	2
Proteasome subunit beta type-8	0	2	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	2	0	2
Proteasome subunit alpha type-5	0	2	0	2
Proteasome subunit beta type-4	0	2	0	2
Proteasome subunit beta type-6	0	2	0	2
Proteasome subunit beta type-5	0	3	0	4
Carbonic anhydrase 5A, mitochondrial	0	4	0	6
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	2	0	2
Carbonic anhydrase 7	0	2	0	4
26S proteasome regulatory subunit 6B	0	1	1	2
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	2	0	2
Proteasome subunit beta type-2	0	2	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	2	0	2
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	4	0	4
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	4	0	7
ATP-dependent Clp protease proteolytic subunit	0	2	2	4
Carbonic anhydrase 13	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	2	0	2
Histone deacetylase 2	0	4	0	4
Proteasome subunit beta type-7	0	2	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	2	0	3
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Carbonic anhydrase 14	0	2	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
Nuclear receptor subfamily 1 group I member 2	0	1	4	5
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	2	1	3
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
15-lipoxygenase, partial	6	0	0	6
Thrombopoietin	6	0	0	6
Metallo-beta-lactamase type 2	0	1	1	4
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	4	1	5
Angiotensin-converting enzyme	0	3	0	4
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	4	0	5
Mu-type opioid receptor	0	0	1	1
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	3	5
Beta-lactamase class B VIM-2	0	1	1	5
USP1 protein, partial	12	0	0	12
Vpr	3	0	0	3
Albumin	0	0	2	2
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 2B6	0	7	2	10
Sodium channel protein type 4 subunit alpha	0	3	0	4
Cytochrome P450 2J2	0	5	0	5
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
GALC protein	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Carbonic anhydrase	0	1	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	3	4
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Amyloid-beta precursor protein	0	4	0	4
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	3	5
Muscarinic acetylcholine receptor M2	0	4	0	5
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	4	3	7
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	5	3	8
Muscarinic acetylcholine receptor M1	0	4	0	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	1	2
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	4	0	5
Serine/threonine-protein kinase mTOR	0	1	0	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	7	0	7
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
huntingtin isoform 2	3	0	0	3
tyrosine-protein kinase Yes	2	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Deoxycytidine kinase	0	0	1	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
nonstructural protein 1	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Cytochrome P450 2C8	0	4	0	6
Liver carboxylesterase 1	0	0	0	3
P2Y purinoceptor 12	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
D	0	1	0	1
Sodium-dependent noradrenaline transporter	0	6	1	7
Sodium-dependent dopamine transporter	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Transporter	0	3	0	3
endonuclease IV	5	0	0	5
PAX8	0	0	0	1
glucocerebrosidase	2	0	0	2
cytochrome P450 2D6 isoform 1	5	0	0	5
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	6	0	0	6
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
neuropeptide S receptor isoform A	6	0	0	6
Solute carrier family 22 member 3	0	5	0	5
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	2
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	2	0	2
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	1	2
ATP-dependent translocase ABCB1	0	2	0	2
Histamine H2 receptor	8	0	0	8
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
dopamine D1 receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	9	0	0	9
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Myeloperoxidase	0	4	0	4
Dihydrofolate reductase	0	3	0	3
Lysine-specific demethylase 6B	0	1	0	1
Lysine-specific demethylase 4A	0	2	1	3
Lysine-specific demethylase 5A	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Sodium channel protein type 5 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
NAD	0	1	0	1
Cholinesterase	0	2	0	2
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	1	2
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	2	0	2
G-protein coupled receptor 35	0	2	2	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
serine/threonine-protein kinase PLK1	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
5-hydroxytryptamine receptor 4	0	4	0	4
Estrogen receptor	0	6	1	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Tyrosine-protein kinase Fyn	0	2	1	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
D(2) dopamine receptor	0	3	0	3
Androgen receptor	0	6	0	6
Alpha-1B adrenergic receptor	0	10	0	10
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	2	0	2
Acetylcholinesterase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
Mu-type opioid receptor	0	7	1	8
D(3) dopamine receptor	0	3	0	3
Vasopressin V1a receptor	0	4	0	4
Alpha-synuclein	3	3	0	6
Delta-type opioid receptor	0	3	1	4
Kappa-type opioid receptor	0	5	1	6
5-hydroxytryptamine receptor 2B	0	2	0	2
Alpha-1A adrenergic receptor	0	10	0	10
Estrogen-related receptor gamma	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Inositol monophosphatase 1	5	0	0	5
Aldehyde oxidase	0	1	0	1
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	1	1	2
Estrogen receptor beta	0	4	1	5
Cysteinyl leukotriene receptor 1	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	2	3
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier family 22 member 7	0	0	0	2
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
5'-nucleotidase	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Albumin	0	1	5	8
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Carbonic anhydrase 13	0	1	0	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
DNA polymerase kappa isoform 1	8	0	0	8
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	2
D(1A) dopamine receptor	2	0	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Thymidine kinase	0	2	0	3
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Parkin	2	0	0	2
pyruvate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Genome polyprotein	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
hypothetical protein, conserved	3	0	0	3
alpha-galactosidase	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Stromelysin-1	0	1	1	2
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	2	0	2
Prostacyclin receptor	0	1	1	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Tyrosine-protein kinase ABL1	0	1	3	5
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	2	3
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	1	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	3	0	4
DNA gyrase subunit A	0	3	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Acetylcholinesterase	0	2	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Cholinesterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Reverse transcriptase/RNaseH	0	1	2	5
Cereblon isoform 4	0	4	0	4
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Zinc finger protein Aiolos	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
DNA polymerase beta	2	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Chain E, Fibrin beta chain	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	4	0	4
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	1	3
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Complement C1r subcomponent	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	3	0	4
Coagulation factor XII	0	1	0	1
Cationic trypsin	0	1	0	1
Interstitial collagenase	0	1	0	1
Serine protease hepsin	0	2	0	2
Cathepsin D	0	1	0	1
Trypsin-1	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Complement C1s subcomponent	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	2	0	2
Hepatocyte growth factor activator	0	2	1	3
Suppressor of tumorigenicity 14 protein	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
beta-2 adrenergic receptor	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
eyes absent homolog 2 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Myosin light chain kinase, smooth muscle	0	1	1	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Beta-2 adrenergic receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
streptokinase A precursor	0	0	3	3
Trypsin	0	0	0	1
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Kappa-type opioid receptor	0	0	1	1
Kappa-type opioid receptor	0	1	0	3
Mu-type opioid receptor	0	0	1	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	2
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	0	2
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Epidermal growth factor receptor	0	2	2	4
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	1	1	2
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	0	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Receptor-type tyrosine-protein kinase FLT3	0	2	1	3
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	1	1	2
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	1	1	2
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	2	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	1	1	2
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Peroxiredoxin-like 2A	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Cystathionine gamma-lyase	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	2	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	2	0	4
Beta-lactamase SHV-1	0	1	0	3
Beta-lactamase SHV-1	0	2	0	4
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	3
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase	0	1	0	2
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	3
Efflux transporter	0	0	0	1
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Metallo-b-lactamase	0	0	0	3
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	4
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase VIM-1	0	0	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Beta-lactamase OXA-7	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Glutamate 5-kinase	0	0	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
NS5	0	0	2	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	2	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	2	0	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	4	0	5
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Protease	0	2	1	5
Multidrug and toxin extrusion protein 2	0	1	0	1
Plasmepsin V	0	1	0	1
Protease	0	2	1	3
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Multidrug resistance-associated protein 5	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Beta-lactamase	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	2
Metallo-beta-lactamase type 2	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
NS3 protease	0	2	0	3
Cathepsin L2	0	1	0	1
Cathepsin S	0	1	0	2
Cathepsin K	0	1	0	1
NS3 protease	0	1	0	1
Cathepsin F	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
Tetracycline resistance protein, class B	0	0	0	1
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Protein kinase C eta type	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Protein kinase C zeta type	0	0	1	1
Serine/threonine-protein kinase D1	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Thymidine kinase, cytosolic	0	2	0	5
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Carbonic anhydrase	0	0	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain B, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, PyrR bifunctional protein	0	0	1	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Uridine 5'-monophosphate synthase	0	1	0	1
UMP-CMP kinase	0	0	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Protein argonaute-2	0	0	1	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (556)

Protein Targets (1,610)

Cryoglobulinemia

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (556)

Drugs Studied (198)

Protein Targets (1,610)