tetracycline and Balanitis

Chancroid, an ulcerous disease of the genitalia caused by Haemophilus ducreyi, occurs rarely but regularly in Germany. Exact diagnosis is based on the clinical features and a direct smear, and in particular on cultivation of the organism, showing its unique macromorphological characteristics. The sensitivity of cultivation has increased due to the development of selective media for primary isolation. Resistance problems during the last decade meant that a change to new therapeutic strategies was unavoidable. The work presented here includes a case report and a review of the recent literature, it illustrates modern methods of diagnosis and treatment of Haemophilus ducreyi infections 100 years after the first description of the organism.

Topics: Administration, Topical; Bacteriological Techniques; Balanitis; Ceftriaxone; Chancroid; Drug Therapy, Combination; Haemophilus ducreyi; Humans; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Middle Aged; Tetracycline

An unusual American epidemic consisting of twenty cases of granuloma inguinale is chronicled. Evidence from this series supports the venereal transmission of the disorder. Trimethoprim/sulfamethoxazole proved to be a safe and effective therapy.

Topics: Administration, Oral; Adult; Balanitis; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Granuloma Inguinale; Homosexuality; Humans; Male; Middle Aged; Sex Work; Sulfamethoxazole; Tetracycline; Texas; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

Aim of the study was to assess both prevalence and antibiotic resistance in anaerobic bacteria from glans penis skin of 70 adults. Strain susceptibility was determined by breakpoint susceptibility test or E test. In 9 asymptomatic, 48 untreated and 13 treated symptomatic patients, anaerobes were found in 22.2%, 70.8% and 53.3%, respectively. Gram-positive strains (GPAs) were 2.2-fold more common than Gram-negative ones. Prevalent Gram-negative (GNAs) and GPAs were Prevotella spp. and anaerobic cocci, respectively. Clostridium difficile strain was found in an untreated patient. In GNAs, resistance rates to amoxicillin, metronidazole, clindamycin, tetracycline, levofloxacin, and amoxicillin/clavulanate were 42.1, 0, 52.6, 53.3, 86.7 and 5.2%, respectively. In GPAs, the resistance rates to metronidazole, clindamycin, tetracycline, levofloxacin and amoxicillin/clavulanate were 18.2, 34.1, 52.6, 36.8 and 0%, respectively. In conclusion, anaerobes were 1.6-fold more frequent in untreated symptomatic patients compared with other patients, suggesting their participation in development of chronic balanitis. GPAs were more common than GNAs. The resistance rates to amoxicillin, clindamycin, tetracycline, and levofloxacin were high. Most active agents were metronidazole and amoxicillin/clavulanate. Resistance in anaerobes varies according to sites of specimens and years of study.

Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Balanitis; Clindamycin; Clostridioides difficile; Drug Resistance, Multiple, Bacterial; Humans; Inhibitory Concentration 50; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Tetracycline; Young Adult

Topics: Animals; Anti-Bacterial Agents; Antipruritics; Balanitis; Behavior, Animal; Cat Diseases; Cats; Chlorpheniramine; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combination; Male; Self Mutilation; Tetracycline

A case of gonococcal urethritis with bilateral tysonitis is discussed. The patient was treated successfully with oral tetracycline 500 mg 6 hourly for 10 days, with a complete resolution.

Topics: Adult; Balanitis; Gonorrhea; Humans; Male; Tetracycline; Urethritis

Fixed drug eruptions are a rarely reported complication of tetracycline therapy. For poorly understood reasons, the epithelium of the glans penis seems unusually susceptible to this type of reaction. We report 3 additional cases of balanitis secondary to orally administered tetracycline and suggest that there may not be cross sensitivity to doxycycline.

Topics: Adult; Aged; Balanitis; Drug Eruptions; Humans; Male; Middle Aged; Penile Diseases; Tetracycline

Topics: Adult; Balanitis; Doxycycline; Drug Eruptions; Humans; Male; Middle Aged; Minocycline; Risk; Tetracycline; Tetracyclines

Topics: Adult; Aminopyrine; Balanitis; Drug Eruptions; Humans; Male; Middle Aged; Phenylbutazone; Tetracycline

Topics: Adult; Balanitis; Drug Hypersensitivity; Humans; Laryngitis; Male; Tetracycline

Topics: Adult; Balanitis; Drug Eruptions; Humans; Male; Tetracycline; Urethritis

Topics: Adult; Aged; Alopecia; Anti-Bacterial Agents; Balanitis; Biopsy; Child; Child, Preschool; Chloramphenicol; Deoxyuridine; Diagnosis, Differential; Diagnostic Errors; Erythromycin; Exanthema; Female; Hemorrhoids; Hernia, Inguinal; Herpes Simplex; Humans; Lymphadenitis; Male; Metronidazole; Middle Aged; Mycoses; Oxytetracycline; Penicillins; Sarcoidosis; Sclerosis; Skin Tests; Stomatitis; Syphilis; Syphilis Serodiagnosis; Syphilis, Latent; Tetracycline