An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol.
ChEBI ID: 25223
| Member | Definition | Role |
|---|---|---|
| busulfan | A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. | busulfan |
| dimethylmyleran | A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. | dimethylmyleran |
| ethofumesate | A methanesulfonate ester that is methanesulfonic acid in which the hydrogen of the hydroxy group has been replaced by a 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl group. | 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate |
| ethyl methanesulfonate | A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol. | ethyl methanesulfonate |
| methyl methanesulfonate | A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol. | methyl methanesulfonate |
| treosulfan | Treosulfan |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3,124 (34.89) | 18.7374 |
| 1990's | 1,665 (18.60) | 18.2507 |
| 2000's | 1,876 (20.95) | 29.6817 |
| 2010's | 1,711 (19.11) | 24.3611 |
| 2020's | 577 (6.44) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 716 (7.33%) | 5.53% |
| Reviews | 373 (3.82%) | 6.00% |
| Case Studies | 511 (5.23%) | 4.05% |
| Observational | 23 (0.24%) | 0.25% |
| Other | 8,143 (83.38%) | 84.16% |