A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration.
| Member | Definition | Role |
|---|
| 1-testosterone | An anabolic steroid that differs from testosterone by having a 1,2-double bond instead of a 4,5-double bond in its A ring. A potent androgen with anabolic properties, it was legally sold as a prohormone in the U.S.A. until 2005, when it was reclassified as a Schedule III drug. | Delta(1)-dihydrotestosterone |
| 11-hydroxytestosterone | An androstanoid that is testosterone carrying an additional hydroxy substituent at the 11beta-position. | 11beta-hydroxytestosterone |
| 11-ketotestosterone | A 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11. | 11-oxotestosterone |
| 15-hydroxytestosterone | An androstanoid that is testosterone substituted by a alpha-hydroxy group at position 15. A natural product found in Daphnia magna exposed to the biocide tributyltin. | 15alpha-hydroxytestosterone |
| 16-hydroxytestosterone | A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group. | 16alpha-hydroxytestosterone |
| 19-hydroxytestosterone | A 3-oxo Delta(4)-steroid that is testosterone which is substituted by a hydroxy group at positions 19. | 19-hydroxytestosterone |
| 2-hydroxyestradiol | A 2-hydroxy steroid that consists of 17beta-estradiol having an additional hydroxy group at position 2. | 2-hydroxy-17beta-estradiol |
| 2-methoxyestradiol | A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2. | 2-methoxy-17beta-estradiol |
| 4-methoxyestradiol | A 17beta-hydroxy steroid that is 17beta-estradiol in which the hydrogen at position 4 has been replaced by a methoxy group. | 4-methoxy-17beta-estradiol |
| 5 alpha-androstane-3 beta,17 beta-diol | An androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone. | 5alpha-androstane-3beta,17beta-diol |
| 6-dehydrotestosterone | A 17beta-hydroxy steroid that is testosterone that contains an additional double bond between positions 6 and 7. | 6-dehydrotestosterone |
| androstane-3,6,17-triol | A 3beta sterol that is 5alpha-androstane which is substituted by beta-hydroxy groups at positions 3 and 17 and by an alpha-hydroxy group at position 6. | 5alpha-androstane-3beta,6alpha,17beta-triol |
| androstane-3,7,17-triol | A 3beta sterol that is 5alpha-androstane which is substituted by beta-hydroxy groups at positions 3 and 17 and by an alpha-hydroxy group at position 7. | 5alpha-androstane-3beta,7alpha,17beta-triol |
| androstenediol | A 3beta-hydroxy-Delta(5)-steroid that is 3beta-hydroxyandrost-5-ene carrying an additional hydroxy group at position 17beta. | androst-5-ene-3beta,17beta-diol |
| boldenone | An 3-oxo-Delta(1),Delta(4)-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been developed for veterinary use. | boldenone |
| danazol | | danazol |
| desogestrel | | desogestrel |
| dienogest | A steroid hormone that is 17beta-hydroxy-3-oxoestra-4,9-diene substituted at position 17 by a cyanomethyl group. Used as an oral contraceptive. | dienogest |
| dihydrotestosterone | A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5. | 17beta-hydroxy-5alpha-androstan-3-one |
| dromostanolone | | metholone |
| estetrol | A 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. | estetrol |
| estradiol 3-benzoate | A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol. | 17beta-estradiol 3-benzoate |
| estradiol-3-glucuronide | A steroid glucosiduronic acid that consists of 17beta-estradiol having a beta-glucuronyl residue attached at position 3 via a glycosidic linkage. | 17beta-estradiol 3-glucosiduronic acid |
| estradiol-3-sulfate | A steroid sulfate obtained by the formal condensation of sulfuric acid with the 3-hydroxy group of 17beta-estradiol. | 17beta-estradiol 3-sulfate |
| estramustine | A carbamate ester obtained by the formal condensation of the hydroxy group of 17beta-estradiol with the carboxy group of bis(2-chloroethyl)carbamic acid. | estramustine |
| estriol | A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer). | estriol |
| estriol 3-glucuronide | A steroid glucosiduronic acid that is the 3-beta-D-glucuronide of estriol; a steroid hormone ligand recognised by the monoclonal antibody 4155. | estriol 3-O-(beta-D-glucuronide) |
| estriol-16 alpha-glucuronide | A steroid glucosiduronic acid that is estriol in which the phenolic hydrogen has been replaced by a beta-D-glucuronyl residue. | estriol 16-O-(beta-D-glucuronide) |
| ethinylestradiol-3-sulfate | A steroid sulfate that is 17alpha-ethynylestradiol in which the phenolic hydrogen at position 3 has been replaced by a sulfo group. | 17alpha-ethynylestradiol 3-sulfate |
| ethisterone | A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol. | ethisterone |
| ethylestrenol | A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth. | ethylestrenol |
| ethynodiol | | ethynodiol |
| etonogestrel | | etonogestrel |
| fluoxymesterone | | fluoxymesterone |
| fulvestrant | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. | fulvestrant |
| ici 164384 | A 3-hydroxy steroid that is 17beta-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines. | ICI-164384 |
| levonorgestrel | | levonorgestrel |
| mestranol | A terminal acetylenic compound that is (17alpha)-17-ethynylestra-1(10),2,4-triene substituted by a methoxy group at position 3 and a hydroxy group at position 17. | mestranol |
| methyltestosterone | A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position. | methyltestosterone |
| metribolone | A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one |
| mibolerone | An androgen that is nalandrone carrying two methyl substituents at positions 7alpha and 17. | mibolerone |
| nandrolone | A 3-oxo Delta(4)-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17. | nandrolone |
| norethindrone | A 17beta-hydroxy steroid that is testosterone in which the hydrogen at position 17 is replaced by an ethynyl group and in which the methyl group attached to position 10 is replaced by hydrogen. | norethisterone |
| oxandrolone | | oxandrolone |
| ru 58668 | A 17beta-hydroxy steroid that is 17beta-estradiol in the the hydrogen at the 11beta position has been replaced by a p-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl group. RU 58668 is a pure anti-estrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). | RU 58668 |
| stanozolol | An organic heteropentacyclic compound resulting from the formal condensation of the 3-keto-aldehyde moiety of oxymetholone with hydrazine. Like oxymetholone, it is a synthetic anabolic steroid. It has both anabolic and androgenic properties, and has been used to treat hereditary angioedema and various vascular disorders. It has also been widely abused by professional athletes. | stanozolol |
| tibolone | Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. | tibolone |
| trilostane | An epoxy steroid that is 3,17beta-dihydroxy-5alpha-androst-2-ene-2-carbonitrile in which the oxygen of the epoxy group is joined to the 4alpha and 5 alpha positions. | trilostane |