An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of inositol-phosphate phosphatase (EC 3.1.3.25).
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 0.5646 | 1 | 3 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.2306 | 1 | 2 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 0.2306 | 1 | 4 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 32.4648 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 4.4780 | 1 | 3 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 29.0522 | 3 | 3 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 21.9744 | 2 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 16.3535 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 5.8353 | 3 | 3 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 26.1216 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 1.4125 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 2.6555 | 1 | 3 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 57.1220 | 2 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.1838 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 12.5893 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 2.1532 | 2 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 14.3335 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 22.6655 | 3 | 5 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 0.0576 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 2.1532 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 13.8154 | 2 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.8554 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 0.5397 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 5.5000 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 14.5500 | 2 | 4 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 4.7444 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 0.0016 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 25.7272 | 4 | 4 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 0.7461 | 1 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 14.5500 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 19.3006 | 4 | 8 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 5.4025 | 2 | 3 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 32.5597 | 1 | 3 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 0.5503 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 0.4496 | 1 | 4 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 11.1471 | 4 | 5 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 17.5594 | 2 | 4 |
| IDH1 | Homo sapiens (human) | Potency | 23.1093 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.0020 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 0.1681 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 17.1216 | 3 | 5 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 18.0789 | 3 | 5 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 4.0027 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 3.5933 | 2 | 6 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 2.1154 | 1 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 29.2953 | 2 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 22.7628 | 2 | 6 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 125.8920 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 28.6954 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 33.8078 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 2.6383 | 1 | 4 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 2.8371 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 0.5661 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.5513 | 5 | 5 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 5.1189 | 4 | 4 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 14.4270 | 1 | 2 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.4054 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 2.9935 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 23.7531 | 1 | 2 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 4.3787 | 2 | 8 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 44.6684 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 14.7715 | 2 | 3 |
| Thrombopoietin | Homo sapiens (human) | Potency | 3.1623 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.8298 | 2 | 2 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 8.9060 | 1 | 4 |