A provitamin that can be converted into vitamin A by enzymes from animal tissues.
ChEBI ID: 67200
| Member | Definition | Class |
|---|---|---|
| alpha-carotene | A cyclic carotene with a beta- and an epsilon-ring at opposite ends respectively. | alpha-carotene |
| beta carotene | A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. | beta-carotene |
| cryptoxanthins | A carotenol that exhibits antioxidant activity. It has been isolated from fruits such as papaya and oranges. | beta-cryptoxanthin |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 590 (7.22) | 18.7374 |
| 1990's | 2,004 (24.51) | 18.2507 |
| 2000's | 2,505 (30.63) | 29.6817 |
| 2010's | 2,280 (27.88) | 24.3611 |
| 2020's | 798 (9.76) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 980 (10.56%) | 5.53% |
| Reviews | 730 (7.86%) | 6.00% |
| Case Studies | 69 (0.74%) | 4.05% |
| Observational | 12 (0.13%) | 0.25% |
| Other | 7,491 (80.70%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 2.6609 | 1 | 1 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 12.5797 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| core protein, partial | IC50 | 35.9842 | 3 | 4 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.6166 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.3400 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 2.9512 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 2.2600 | 1 | 1 |