Page last updated: 2024-09-28

Eunuchism

The state of being a eunuch, a male without TESTES or whose testes failed to develop. It is characterized by the lack of mature male GERM CELLS and TESTICULAR HORMONES.

Synonyms(3)

Synonym
Eunuchism
Eunuchoidism
Hypogonadism, Male

Research Excerpts

Overview

ExcerptReference
"A case of fertile eunuchoidism is presented."( Bolté, E; del Pozo, E; Very, M, 1975)

Treatment

ExcerptReference
"Testosterone replacement therapy for male hypogonadism can provoke fatal cardiovascular events."( , 2014)
"Men with male hypogonadism (MH) experience sexual dysfunction, which improves with testosterone replacement therapy (TRT)."( Aceves-Martins, M; Aucott, L; Bhattacharya, S; Brazzelli, M; Cruickshank, M; Dhillo, WS; Gillies, K; Hernandez, R; Hudson, J; Jayasena, CN; Manson, P; Oliver, N; Quinton, R; Wu, F, 2022)

Research

Studies (253)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990145 (57.31)23.3326
1990's10 (3.95)12.5806
2000's7 (2.77)18.1394
2010's68 (26.88)28.8240
2020's23 (9.09)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carnitine0low10
hydrogen sulfide0low10
iodine0low10
thiamine0low10
uric acid0low10
vanillin0low10
menthol0low10
acetaminophen0low10
acetovanillone0low10
berberine0low10
chlorpromazine0low10
2-propanol0low10
metformin0medium21
metyrapone0low30
estriol0low20
thyroxine0low30
prednisone0low10
estrone0low40
oxandrolone0medium11
androsterone0low40
etiocholanolone0low30
dehydroepiandrosterone0low80
triiodothyronine0low10
ethinyl estradiol0low10
testosterone propionate0low10
methyltestosterone0low50
threonine0low10
tryptophan0low10
isoleucine0low10
arginine0low30
fluoxymesterone0low10
trehalose0low10
benzonitrile0low10
nandrolone0low20
dihydrotestosterone0low60
dehydroepiandrosterone sulfate0low10
manganese0low10
trolamine salicylate0low10
pyrrolidine0low10
fludrocortisone0low10
8-bromo cyclic adenosine monophosphate0low10
colforsin0low10
cabergoline0low10
fibrinogen0low10
homocysteine0low10
pregnanetriol0low10
tadalafil0medium11
cortisone0low10
methandriol0low10
glycogen0low10
diethylstilbestrol0low10
enclomiphene0low150
D-fructopyranose0low30
tamoxifen0low10
17-ketosteroids0low270
phosphorus0low20
pregnanediol0low10
ergoline0low10
pituitrin0low10
acid phosphatase0low20
glucagon0low10
cellulose0low20
menotropins0low50
sodium ethylxanthate0low10
methylcellulose0low20
ascorbic acid0low10
tetracycline0low10
vardenafil dihydrochloride0low10
leptin0low20

Protein Targets (817)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit8008
RAR-related orphan receptor gamma210021
GLI family zinc finger 3250025
AR protein270027
aldehyde dehydrogenase 1 family, member A1110011
retinoic acid nuclear receptor alpha variant 1250025
retinoid X nuclear receptor alpha210021
estrogen nuclear receptor alpha300030
peroxisome proliferator-activated receptor delta150015
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a180018
activating transcription factor 69009
v-jun sarcoma virus 17 oncogene homolog (avian)140014
Histone H2A.x110011
thyroid hormone receptor beta isoform a8008
heat shock protein beta-1100010
nuclear factor erythroid 2-related factor 2 isoform 1220022
lamin isoform A-delta10140014
Voltage-dependent calcium channel gamma-2 subunit120012
Glutamate receptor 2120012
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
ATAD5 protein, partial4004
GLS protein6006
Microtubule-associated protein tau9009
Smad37007
thyroid stimulating hormone receptor8008
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor220022
EWS/FLI fusion protein5005
estrogen-related nuclear receptor alpha230023
peroxisome proliferator activated receptor gamma210021
aryl hydrocarbon receptor110011
chromobox protein homolog 1160016
thyroid hormone receptor beta isoform 2200020
peripheral myelin protein 22100010
cytochrome P450 3A4 isoform 1120012
Gamma-aminobutyric acid receptor subunit pi121114
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 409010
Solute carrier family 22 member 60101
Carbonic anhydrase 120102
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0202
Bile salt export pump014014
Cytochrome P450 2B10102
Cytochrome P450 1A10001
Carbonic anhydrase 10405
Carbonic anhydrase 20405
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20113
Prostaglandin G/H synthase 10101
Carbonic anhydrase 30102
Cytochrome P450 3A40405
Cytochrome P450 2D60415
Cytochrome P450 2C9 0202
Polyunsaturated fatty acid lipoxygenase ALOX150606
Gamma-aminobutyric acid receptor subunit beta-1121114
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta121114
Gamma-aminobutyric acid receptor subunit gamma-2121114
UDP-glucuronosyltransferase 1-60001
Gamma-aminobutyric acid receptor subunit alpha-5121114
Gamma-aminobutyric acid receptor subunit alpha-3121114
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0204
Carbonic anhydrase 40203
Prostaglandin G/H synthase 10404
Carbonic anhydrase 60304
Gamma-aminobutyric acid receptor subunit gamma-1121114
Gamma-aminobutyric acid receptor subunit alpha-2121114
Gamma-aminobutyric acid receptor subunit alpha-4121114
Gamma-aminobutyric acid receptor subunit gamma-3121114
Gamma-aminobutyric acid receptor subunit alpha-6121114
Carbonic anhydrase 5A, mitochondrial0203
Prostaglandin G/H synthase 20001
Carbonic anhydrase 70203
Nuclear receptor ROR-gamma9009
Cytochrome P450 2J20202
Gamma-aminobutyric acid receptor subunit alpha-1121114
Gamma-aminobutyric acid receptor subunit beta-3121114
Gamma-aminobutyric acid receptor subunit beta-2121114
Carbonic anhydrase 90203
GABA theta subunit121114
Canalicular multispecific organic anion transporter 10808
Carbonic anhydrase 150102
Carbonic anhydrase 130203
Gamma-aminobutyric acid receptor subunit epsilon121114
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0203
toxin B0001
TDP1 protein220022
geminin210021
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
interleukin 85005
acetylcholinesterase100010
SMAD family member 26006
SMAD family member 36006
estrogen receptor 2 (ER beta)170017
regulator of G-protein signaling 44004
cytochrome P450 family 3 subfamily A polypeptide 4150015
nonstructural protein 12002
glucocorticoid receptor [Homo sapiens]230023
farnesoid X nuclear receptor140014
pregnane X nuclear receptor220022
vitamin D (1,25- dihydroxyvitamin D3) receptor180018
Caspase-74004
Bloom syndrome protein isoform 13003
peripheral myelin protein 22 isoform 14004
potassium voltage-gated channel subfamily H member 2 isoform d4004
caspase-34004
importin subunit beta-1 isoform 13003
mitogen-activated protein kinase 14004
nuclear factor NF-kappa-B p105 subunit isoform 11001
snurportin-13003
GTP-binding nuclear protein Ran isoform 13003
DNA polymerase iota isoform a (long)4004
nuclear receptor ROR-gamma isoform 16006
survival motor neuron protein isoform d6006
muscleblind-like protein 1 isoform 12002
neuropeptide S receptor isoform A3003
Sex hormone-binding globulin011112
Beta-glucuronidase0202
Cholinesterase0202
Corticosteroid-binding globulin0909
Aromatase0508
Androgen receptor018119
Gastrin/cholecystokinin type B receptor0001
Testosterone 17-beta-dehydrogenase 30303
Alpha-synuclein4408
TAR DNA-binding protein 439009
Chain A, retinol dehydratase0101
histone acetyltransferase KAT2A isoform 14004
Glucose-6-phosphate 1-dehydrogenase0404
Solute carrier organic anion transporter family member 1A10304
G-protein coupled bile acid receptor 10055
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase8008
phosphopantetheinyl transferase7007
NFKB1 protein, partial3003
alpha-galactosidase1001
euchromatic histone-lysine N-methyltransferase 29009
cytochrome P450 2C19 precursor2002
flap endonuclease 13003
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)5005
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase3003
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase3003
IDH16006
nuclear factor erythroid 2-related factor 2 isoform 22002
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Polyphenol oxidase 20202
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0819
Spike glycoprotein5128
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Fumarate hydratase4004
PPM1D protein3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
polyprotein4004
cytochrome P450 2D6 isoform 13003
Telomerase reverse transcriptase0101
Acetylcholinesterase0101
Lysine-specific histone demethylase 1A0101
Interferon beta120012
Neuraminidase0101
Neuraminidase0101
Tyrosine-protein phosphatase non-receptor type 10101
Acetylcholinesterase0202
Aldo-keto reductase family 1 member C30101
Prolyl endopeptidase0101
Aldo-keto reductase family 1 member C2 0101
Cholinesterase0101
Inositol monophosphatase 13003
Potassium voltage-gated channel subfamily H member 20606
Cytochrome P450 1B10303
cytochrome P450 2D66006
thyroid stimulating hormone receptor100010
Cellular tumor antigen p53140014
5-hydroxytryptamine receptor 2B011112
Histamine H3 receptor0202
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Proteasome subunit beta type-110001
USP1 protein, partial100010
Thrombopoietin1001
caspase 7, apoptosis-related cysteine protease4004
NADPH oxidase 10101
G8008
67.9K protein5005
Snq2p0001
caspase-34004
Adenylate cyclase type 1 0202
Spike glycoprotein0123
Replicase polyprotein 1ab0123
cellular tumor antigen p53 isoform a3003
D(1A) dopamine receptor2002
vitamin D3 receptor isoform VDRA8008
histone deacetylase 9 isoform 32002
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 12002
DNA polymerase kappa isoform 13003
M-phase phosphoprotein 84004
Proteasome subunit alpha type-70001
Solute carrier family 22 member 1 0405
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Transmembrane protease serine 20123
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
5-hydroxytryptamine receptor 40808
Potassium channel subfamily K member 20101
Epidermal growth factor receptor0303
HLA class I histocompatibility antigen, B alpha chain 8008
Albumin0011
Albumin0011
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Receptor tyrosine-protein kinase erbB-20303
Major prion protein0011
Integrin beta-33003
Tyrosine-protein kinase Fyn0404
Procathepsin L0123
Aldo-keto reductase family 1 member B1010010
Muscarinic acetylcholine receptor M20707
Muscarinic acetylcholine receptor M40606
ATP-dependent translocase ABCB10416
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Integrin alpha-IIb3003
5-hydroxytryptamine receptor 1A0202
5-hydroxytryptamine receptor 2C0101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0808
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0123
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10808
Angiotensin-converting enzyme0404
D(2) dopamine receptor0607
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor011011
Sphingomyelin phosphodiesterase0101
Alpha-2C adrenergic receptor0606
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0202
D(2) dopamine receptor0101
Muscarinic acetylcholine receptor M30808
Proteasome subunit beta type-10001
Substance-K receptor0808
D(1A) dopamine receptor0607
D(4) dopamine receptor0405
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0202
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Sodium-dependent noradrenaline transporter 010010
Sodium-dependent dopamine transporter0202
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0606
D(1B) dopamine receptor0202
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20213
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A0808
5-hydroxytryptamine receptor 2C0808
5-hydroxytryptamine receptor 1B0404
Trypanothione reductase0202
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 2B0101
Histamine H1 receptor0101
Sodium-dependent serotonin transporter014014
Melanocortin receptor 40404
5-hydroxytryptamine receptor 7 0101
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0202
Mu-type opioid receptor0808
Glutamate receptor ionotropic, NMDA 1 0102
D(3) dopamine receptor0809
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0606
Kappa-type opioid receptor0808
Melanocortin receptor 30404
Alpha-1A adrenergic receptor011011
Histamine H2 receptor4004
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60808
5-hydroxytryptamine receptor 70202
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60012
D(2) dopamine receptor0203
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0102
Glutamate receptor ionotropic, NMDA 2B0102
Glutamate receptor ionotropic, NMDA 2C0102
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 010010
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0404
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2D0102
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0102
Inositol hexakisphosphate kinase 18008
D0101
Sodium channel protein type 2 subunit alpha0101
Proteasome subunit beta type-70001
Ataxin-24004
Sigma non-opioid intracellular receptor 10606
Angiotensin-converting enzyme 2 0123
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0102
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial8008
Chain A, Ferritin light chain4004
Chain A, Cruzipain1001
Luciferase5005
15-lipoxygenase, partial2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Vitamin D3 receptor0114
Glycine receptor subunit alpha-10011
Vitamin D3 receptor0011
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
glp-1 receptor, partial5005
pregnane X receptor7007
nuclear receptor subfamily 1, group I, member 22002
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
relaxin receptor 1 isoform 11001
relaxin receptor 2 isoform 11001
Nuclear receptor subfamily 1 group I member 20123
Rap guanine nucleotide exchange factor 35005
Solute carrier family 2, facilitated glucose transporter member 10011
Adenylate cyclase type 80011
Adenylate cyclase type 10112
ATPase family AAA domain-containing protein 53003
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20011
endonuclease IV2002
dopamine D1 receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a120012
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor013115
Glycine receptor subunit alpha-1012012
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10303
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Beta-glucuronidase0101
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Solute carrier organic anion transporter family member 1A40104
Solute carrier organic anion transporter family member 1A50003
Steryl-sulfatase0102
Multidrug resistance-associated protein 1 0001
Solute carrier organic anion transporter family member 1A20003
Solute carrier organic anion transporter family member 1A30003
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30002
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier organic anion transporter family member 1B10003
Chain A, JmjC domain-containing histone demethylation protein 3A3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
serine/threonine-protein kinase PLK12002
high affinity choline transporter 1 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Estrogen receptor012418
Beta-1 adrenergic receptor0404
Polyunsaturated fatty acid 5-lipoxygenase0303
Adenosine receptor A30808
Thromboxane-A synthase 0202
Adenosine receptor A2a0606
Adenosine receptor A10606
Vasopressin V1a receptor0202
Estrogen-related receptor gamma0112
Disintegrin and metalloproteinase domain-containing protein 171001
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140101
Estrogen receptor beta06411
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Cysteinyl leukotriene receptor 10202
Chain A, Sex Hormone-Binding Globulin0011
thyrotropin-releasing hormone receptor2002
transcriptional regulator ERG isoform 34004
Plasma kallikrein0102
Progesterone receptor0101
Progesterone receptor0213
Glucocorticoid receptor0101
Mineralocorticoid receptor 0101
Sex hormone-binding globulin0101
Androgen receptor08314
Androgen receptor0123
Mineralocorticoid receptor0101
Angiotensin-converting enzyme0011
Cannabinoid receptor 20101
Muscarinic acetylcholine receptor0101
Neuropeptide FF receptor 20002
ALK tyrosine kinase receptor0101
Chain A, Beta-lactamase4004
chaperonin-containing TCP-1 beta subunit homolog1001
bromodomain adjacent to zinc finger domain 2B3003
ubiquitin-conjugating enzyme E2 N0202
protein AF-9 isoform a0001
Beta-3 adrenergic receptor0404
C-8 sterol isomerase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0314
UDP-glucuronosyltransferase 2B70001
Lanosterol 14-alpha demethylase0011
Olfactory receptor 51E20011
UDP-glucuronosyltransferase 1A100001
GALC protein3003
arylsulfatase A3003
hexokinase-4 isoform 11001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
glucokinase regulatory protein1001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
17-beta-hydroxysteroid dehydrogenase type 10203
Mu-type opioid receptor0011
Mu-type opioid receptor0011
Ghrelin O-acyltransferase0101
lysosomal alpha-glucosidase preproprotein1001
Vpr1001
Solute carrier family 22 member 20202
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Cytochrome P450 2B60202
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sulfotransferase 1A10214
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
ClpP1001
Guanine nucleotide-binding protein G1001
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
2-dehydropantoate 2-reductase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0102
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0102
Transient receptor potential cation channel subfamily A member 10011
Large neutral amino acids transporter small subunit 10202
Proton-coupled amino acid transporter 10202
Transient receptor potential cation channel subfamily A member 10011
Secreted chorismate mutase0202
Transient receptor potential cation channel subfamily M member 80124
Transient receptor potential cation channel subfamily A member 10011
Transient receptor potential cation channel subfamily M member 80011
Dihydrofolate reductase0303
Dipeptidyl peptidase 40101
Solute carrier family 22 member 10102
glucocerebrosidase4004
Steroid 17-alpha-hydroxylase/17,20 lyase0202
Cytochrome P450 2C80101
Cytochrome P450 11B1, mitochondrial 0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Cytochrome P450 2C190101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0213
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Acetylcholinesterase0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Synaptic vesicular amine transporter0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Nuclear receptor subfamily 2 group E member 10011
Chain A, CES1 protein0101
apical membrane antigen 1, AMA13003
DNA polymerase III, partial1001
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
streptokinase A precursor0011
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Protein kinase C iota type0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
cytochrome P450 2C9 precursor1001
Rap guanine nucleotide exchange factor 41001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10202
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
Solute carrier family 22 member 80102
P2Y purinoceptor 120101
Protein-arginine deiminase type-40101
Solute carrier family 22 member 70001
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Solute carrier family 22 member 20101
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidylate synthase0001
Thymidine phosphorylase0001
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose0101
Trehalose-phosphatase0101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Prothrombin0011
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma non-opioid intracellular receptor 10011
Solute carrier organic anion transporter family member 4C10001
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Chain A, 2-oxoglutarate Oxygenase1001
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 22 member 60001
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Transcription intermediary factor 1-alpha0101
Pancreatic triacylglycerol lipase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
DNA-dependent protein kinase catalytic subunit0101
4-aminobutyrate aminotransferase, mitochondrial0101
E3 ubiquitin-protein ligase TRIM330101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]