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cyanine dye
Cyanine dyes are synthetic dyes with the general formula R2N[CH=CH]nCH=N(+)R2 <-> R2N(+)=CH[CH=CH]nNR2 (n is a small number) in which the nitrogen and part of the conjugated chain usually form part of a heterocyclic system, such as imidazole, pyridine, pyrrole, quinoline and thiazole.
ChEBI ID: 37960
Members (21)
| Member | Definition | Role |
|---|---|---|
| 1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidine)quinolinium, tetraiodide | YoYo-1 | |
| 1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium | ToTo-1 | |
| 2-(dimethylaminostyryl)-1-ethylpyridinium | 2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide | |
| 3,3'-diethyloxacarbocyanine | The cationic form of a C3 cyanine dye having 3-ethyl-1,3-benzoxazol-2(3H)-yl units at each end. | C3-oxacyanine cation |
| 3,3'-diethylthiacarbocyanine iodide | C3-thiacarbocyanine | |
| 3,3'-diethylthiacarbocyanine iodide | C3-thiacarbocyanine | |
| 3,3'-dipentyl-2,2'-oxacarbocyanine | The cationic form of a C3 cyanine dye having 3-pentyl-1,3-benzoxazol-2(3H)-yl units at each end. A fluorescent compound that preferentially stains chronic myelogenic leukemia cells. | 3,3'-dipentyloxacarbocyanine |
| 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine | The cationic form of a C3 cyanine dye having 1,3-diethyl-5,6-dichloroindoleinine units at each end. | 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine |
| bobo 3 | BoBo-3 | |
| carbocyanines | pinacyanol iodide | |
| indocyanine green | indocyanine green | |
| indocyanine green | indocyanine green | |
| picogreen | A cyanine dye that is 1-phenylquinoline which is substituted at position 2 by a bis[3-(dimethylamino)propyl]amino group and at position 4 by a (3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene group. The counter ion is not stated. A fluorochrome that selectively binds double-stranded DNA and has characteristics similar to that of SYBR-Green I. | PicoGreen |
| quinaldine blue | pinacyanol iodide | |
| stains-all | carbocyanin DBTC | |
| sybr green i | A benzothiazolium ion resulting from the methylation of the nitrogen of the benzothiazole group of N-[4-(1,3-benzothiazol-2-ylmethylene)-1-phenyl-1,4-dihydroquinolin-2-yl]-N',N'-dimethyl-N-propylpropane-1,3-diamine. A cationic unsymmetrical cyanine dye that binds to double-stranded DNA and is used as a nucleic acid stain in molecular biology. | SYBR Green I |
| thiazole orange | A cyanine dye comprising the thiazole orange cation [1-methyl-4-[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]quinolinium] with the p-tosylate counterion. | thiazole orange |
| to-pro-1 | A C1 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents. | To-Pro-1 |
| to-pro-3 | An unsymmetrical C3 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents. | To-Pro-3 |
| yo-pro 1 | An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents. | Yo-Pro-1 |
| yoyo-3 | YoYo-3 |
Research
Studies (16,154)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,457 (9.02) | 18.7374 |
| 1990's | 1,952 (12.08) | 18.2507 |
| 2000's | 3,853 (23.85) | 29.6817 |
| 2010's | 6,121 (37.89) | 24.3611 |
| 2020's | 2,771 (17.15) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 597 (3.40%) | 5.53% |
| Reviews | 645 (3.68%) | 6.00% |
| Case Studies | 1,395 (7.95%) | 4.05% |
| Observational | 143 (0.81%) | 0.25% |
| Other | 14,768 (84.16%) | 84.16% |