Roles > oxidising agent
Page last updated: 2024-08-05 14:35:02

oxidising agent

A substance that removes electrons from another reactant in a redox reaction.

ChEBI ID: 63248

Members (18)

MemberDefinitionClass
2,2'-dipyridyl disulfideA member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols.aldrithiol
acetaldehydeThe aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.acetaldehyde
ammonium nitrateThe ammonium salt of nitric acid.ammonium nitrate
carbamide peroxideA mixture obtained by combining equimolar amounts of hydrogen peroxide and urea.urea hydrogen peroxide
chromatesA chromium oxoanion resulting from the removal of two protons from chromic acid.chromate(2-)
chromic acidchromic acid
cumene hydroperoxideA peroxol that is cumene in which the alpha-hydrogen is replaced by a hydroperoxy group.cumene hydroperoxide
hypothiocyanite ionA sulfur oxoacid that is sulfenic acid in which the hydrogen attached to the sulfur has been replaced by a cyano group.hypothiocyanous acid
nitrogen tetroxidedinitrogen tetraoxide
o-iodoxybenzoic acidA benziodoxole compound having hydroxy and oxo substituents at the 1-position and an oxo substituent at the 3-position. It is a mild and efficient hypervalent iodine synthetic reagent used to carry out several selective oxidation reactions.1-hydroxy-1,3-dioxobenziodoxole
osmium tetroxideAn osmium coordination entity consisting of four oxygen atoms bound to a central osmium atom via covalent double bonds.osmium tetroxide
ozoneAn elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.ozone
peracetic acidA peroxy acid that is acetic acid in which the OH group is substituted by a hydroperoxy group. It is a versatile oxidising agent that is used as a disinfectant.peracetic acid
potassium chromate(vi)A potassium salt consisting of potassium and chromate ions in a 2:1 ratio.potassium chromate
potassium dichromateA potassium salt that is the dipotassium salt of dichromic acid.potassium dichromate
sodium bromateAn inorganic sodium salt having bromate as the counterion.sodium bromate
sodium chromate(vi)An inorganic sodium salt consisting of sodium and chromate ions in a 2:1 ratio.sodium chromate
tert-butylhydroperoxideAn alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.tert-butyl hydroperoxide

Research

Studies (30,872)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19906,878 (22.28)18.7374
1990's4,273 (13.84)18.2507
2000's7,970 (25.82)29.6817
2010's8,379 (27.14)24.3611
2020's3,372 (10.92)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials829 (2.47%)5.53%
Reviews1,889 (5.63%)6.00%
Case Studies419 (1.25%)4.05%
Observational43 (0.13%)0.25%
Other30,396 (90.53%)84.16%

Protein Targets (85)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-lipoxygenase, partialHomo sapiens (human)Potency0.125911
acetylcholinesteraseHomo sapiens (human)Potency47.477133
activating transcription factor 6Homo sapiens (human)Potency43.704013
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency30.699514
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency39.810711
AR proteinHomo sapiens (human)Potency19.2994820
aryl hydrocarbon receptorHomo sapiens (human)Potency63.110011
Ataxin-2Homo sapiens (human)Potency19.781812
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency19.781812
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency40.758812
caspase-3Cricetulus griseus (Chinese hamster)Potency71.740311
caspase-3Homo sapiens (human)Potency40.758812
Caspase-7Cricetulus griseus (Chinese hamster)Potency71.740311
Cellular tumor antigen p53Homo sapiens (human)Potency24.452838
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency10.000011
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency12.589311
Chain A, CruzipainTrypanosoma cruziPotency22.387211
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency3.981111
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency25.118911
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency22.387211
chromobox protein homolog 1Homo sapiens (human)Potency11.220211
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency17.356414
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency22.387211
DNA polymerase kappa isoform 1Homo sapiens (human)Potency29.934911
estrogen nuclear receptor alphaHomo sapiens (human)Potency18.32711120
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency79.078812
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency11.8448613
farnesoid X nuclear receptorHomo sapiens (human)Potency27.711058
flap endonuclease 1Homo sapiens (human)Potency89.125111
gemininHomo sapiens (human)Potency15.701922
GLI family zinc finger 3Homo sapiens (human)Potency24.8242210
GLS proteinHomo sapiens (human)Potency10.000011
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency16.3247512
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency15.661012
Glycoprotein hormones alpha chainHomo sapiens (human)Potency10.000011
heat shock protein beta-1Homo sapiens (human)Potency57.801427
Histone H2A.xCricetulus griseus (Chinese hamster)Potency66.742424
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency39.810711
hypothetical protein, conservedTrypanosoma bruceiPotency25.118911
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency41.289523
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency15.848911
IDH1Homo sapiens (human)Potency25.929011
interleukin 8Homo sapiens (human)Potency74.978011
LuciferasePhotinus pyralis (common eastern firefly)Potency32.016211
mitogen-activated protein kinase 1Homo sapiens (human)Potency100.000011
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency40.6280310
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency48.286813
Nuclear receptor ROR-gammaHomo sapiens (human)Potency41.854614
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency35.481311
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency31.272227
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency26.225345
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency44.352636
pregnane X nuclear receptorHomo sapiens (human)Potency6.620212
pregnane X receptorRattus norvegicus (Norway rat)Potency44.668411
progesterone receptorHomo sapiens (human)Potency28.560311
RAR-related orphan receptor gammaMus musculus (house mouse)Potency25.655426
regulator of G-protein signaling 4Homo sapiens (human)Potency56.234111
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency24.816836
retinoid X nuclear receptor alphaHomo sapiens (human)Potency20.548933
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency0.670211
SMAD family member 2Homo sapiens (human)Potency22.884823
SMAD family member 3Homo sapiens (human)Potency22.884823
Smad3Homo sapiens (human)Potency22.387211
TAR DNA-binding protein 43Homo sapiens (human)Potency12.589311
TDP1 proteinHomo sapiens (human)Potency13.541124
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency25.0351312
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency29.881622
thyroid stimulating hormone receptorHomo sapiens (human)Potency39.069948
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency42.699322
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency64.537011
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency37.066945
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency3.162311
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency15.661012
VprHuman immunodeficiency virus 1Potency44.668411
WRNHomo sapiens (human)Potency22.387211

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
DNA dC->dU-editing enzyme APOBEC-3A isoform aHomo sapiens (human)IC50100.000011
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)IC503.880011
glucose-6-phosphate 1-dehydrogenase isoform bHomo sapiens (human)IC5080.000011
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium bergheiIC5044.906733
Histone-lysine N-methyltransferase EHMT1Homo sapiens (human)IC502.700011
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)IC500.650011
large T antigenBetapolyomavirus macacaeIC50100.000011
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC501,160.000011
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)Ki17,000.000011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
MSRA proteinBos taurus (cattle)EC50103.879011