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20-hydroxy steroid

Any hydroxy steroid that in which the steroid skeleton contains a hydroxy substituent at position 20.

ChEBI ID: 36854

Members (10)

MemberDefinitionRole
(20s)-20-hydroxycholesterolAn oxysterol that is cholesterol substituted by a hydroxy group at position 20.20-hydroxycholesterol
20 beta-dihydroprogesteroneA C21-steroid that is pregnane which contains a double bond between positions 4 and 5 and is substituted by an oxo group at position 3 and a hydroxy group at position 20.20-hydroxypregn-4-en-3-one
20,22-dihydroxycholesterolAn oxysterol that is cholesterol substituted by hydroxy groups at positions 20 and 22 (the 20R,22R-stereoisomer).(20R,22R)-20,22-dihydroxycholesterol
cyasteronecyasterone
ecdysteroneAn ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.20-hydroxyecdysone
ginsenoside rfA ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside Rf
ginsenoside rg2A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside Rg2
ginsenoside rh2A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.(20S)-ginsenoside Rh2
ponasterone aponasterone A
withanolide dA withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 22 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Tubocapsicum anomalum and Withania somnifera, it exhibits cytotoxic activity.withanolide D

Research

Studies (2,212)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990391 (17.68)18.7374
1990's327 (14.78)18.2507
2000's569 (25.72)29.6817
2010's658 (29.75)24.3611
2020's267 (12.07)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials11 (0.44%)5.53%
Reviews58 (2.32%)6.00%
Case Studies1 (0.04%)4.05%
Observational0 (0.00%)0.25%
Other2,434 (97.20%)84.16%