Page last updated: 2024-08-05 11:13:22

oxacycle

Any organic heterocyclic compound containing at least one ring oxygen atom.

ChEBI ID: 38104

Members (64)

MemberDefinitionRole
(2R)-1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-methylbutane-2,3-diol(2R)-1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-methylbutane-2,3-diol
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone
1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester
1-[2-(diethylamino)ethyl]-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione1-[2-(diethylamino)ethyl]-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione
1,4-dioxinAn oxacycle that is 4H-pyran in which the methylene group at position 4 is replaced by an oxygen. Non-aromatic.1,4-dioxine
2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one
2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-oxo-2-(4-phenylbutan-2-ylamino)ethyl] ester2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-oxo-2-(4-phenylbutan-2-ylamino)ethyl] ester
3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl ester3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl ester
4-hydroxy-6-propan-2-ylpyrano[3,2-c]quinoline-2,5-dione4-hydroxy-6-propan-2-ylpyrano[3,2-c]quinoline-2,5-dione
4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamide4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamide
6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamide6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamide
6,6'-bieckolA phlorotanin that is 1,1'-bioxanthrene substituted by 3,5-dihydroxyphenoxy groups at position 6 and 6' and hydroxy groups at positions 2, 2', 4, 4', 7, 7', 9 and 9' respectively. It is isolated from an edible marine brown alga Ecklonia cava and exhibits antioxidant activity.6,6'-bieckol
7-amino-5-(4-ethoxy-3-methoxyphenyl)-4-oxo-3,5-dihydropyrano[2,3-d]pyrimidine-6-carbonitrile7-amino-5-(4-ethoxy-3-methoxyphenyl)-4-oxo-3,5-dihydropyrano[2,3-d]pyrimidine-6-carbonitrile
7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamide7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamide
acetic acid [1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-hydroxy-3-methylbutan-2-yl] esteracetic acid [1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-hydroxy-3-methylbutan-2-yl] ester
acetosulfameA sulfamate ester that is 1,2,3-oxathiazin-4(3H)-one 2,2-dioxide substituted by a methyl group at position 6.acesulfame
anonaineAn aporphine alkaloid that exhibits anti-cancer, trypanocidal and antiplasmodial activites.(-)-annonaine
bulbocapnineAn aporphine alkaloid that has been isolated from Corydalis and exhibits inhibitory activity against enzymes such as tyrosine 3-monooxygenase and diamine oxidase.bulbocapnine
canadineA berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.canadine
carboxinAn anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment.carboxin
cimifuginCimifugin
cinoxacinA member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.cinoxacin
decarestrictine dDecarestrictine D
dibenzo(1,4)dioxinoxanthrene
dictamnineDictamnine
dieckolA phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities.dieckol
DubinidineDubinidine
eckstolonolA phlorotannin that is [1,4]benzodioxino[2,3-a]oxanthrene substituted by hydroxy groups at positions 1, 3, 6, 9 and 11. Isolated from the brown alga Ecklonia stolonifera, it exhibits radical scavenging activity.eckstolonol
ep 2013,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6-methylcyclo-hexanecarboxylate
ethylene oxideA saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.oxirane
EvoxineEvoxine
flindersiamineFlindersiamine
flindersineFlindersine
gamma-fagarinegamma-Fagarine
haplamine9-Methoxy-2,2-dimethyl-6H-pyrano[3,2-c]quinolin-5-one
heliparvifolineHaplopine
hematoxylinAn organic heterotetracyclic compound 7,11b-dihydroindeno[2,1-c]chromene carrying five hydroxy substituents at positions 3, 4, 6a, 9 and 10. The most important and most used dye in histology, histochemistry, histopathology and in cytology.haematoxylin
hemibrevetoxin bHemibrevetoxin B
interiotherin bA lignan with a dibenzocyclooctadiene skeleton attached to a fatty acid ester side chain. It is isolated from Kadsura interior and has been shown to exhibit anti-HIV activity.interiotherin B
iriloneA hydroxyisoflavone that is 6,7-methylenedioxyisoflavone substituted by hydroxy groups at positions 5 and 4'.irilone
jnj162596853,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone
khellinA furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.khellin
khellosideKhellol glucoside
kokusaginineKokusaginine
lamivudineA monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B.lamivudine
liriodenineAn oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities.liriodenine
LSM-31277LSM-31277
LSM-31434LSM-31434
maculineMaculine
muromonab-cd3An organic heteropentacyclic compound that is isolated from the marine sponge Xestospongia exigua.xestospongin C
mycalamide bMycalamide B
N-[2-(dipropylamino)ethyl]-4-methyl-2-furo[3,2-c]quinolinecarboxamideN-[2-(dipropylamino)ethyl]-4-methyl-2-furo[3,2-c]quinolinecarboxamide
oxetoroneoxetorone
oxireneoxirene
oxolinic acidA quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry.oxolinic acid
oxycarboxinAn anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-4,4-dioxo-1,4-oxathiine-3-carboxylic acid. A fungicide for the control of rust diseases on ornamentals, cereals and nursery trees as well as fairy rings on turf.oxycarboxin
pinolidoxinPinolidoxin
pr toxinPR-toxin
prim-o-glucosylcimifuginPRIM-O-GLUCOSYLCIMIFUGIN
rotundifoloneRotundifolone
schizandrin bAn organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis.(+)-schisandrin B; Deoxygomisin A
skimmianineSkimmianine
tirandamycin aTirandamycin
tripdiolideTripdiolide

Research

Studies (17,574)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,322 (18.90)18.7374
1990's2,237 (12.73)18.2507
2000's5,441 (30.96)29.6817
2010's4,678 (26.62)24.3611
2020's1,896 (10.79)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,721 (8.88%)5.53%
Reviews1,572 (8.11%)6.00%
Case Studies1,576 (8.13%)4.05%
Observational91 (0.47%)0.25%
Other14,417 (74.40%)84.16%