Page last updated: 2024-08-05 11:13:22
oxacycle
Any organic heterocyclic compound containing at least one ring oxygen atom.
ChEBI ID: 38104
Members (64)
| Member | Definition | Role |
|---|---|---|
| (2R)-1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-methylbutane-2,3-diol | (2R)-1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-methylbutane-2,3-diol | |
| [4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone | [4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone | |
| 1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester | 1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester | |
| 1-[2-(diethylamino)ethyl]-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione | 1-[2-(diethylamino)ethyl]-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione | |
| 1,4-dioxin | An oxacycle that is 4H-pyran in which the methylene group at position 4 is replaced by an oxygen. Non-aromatic. | 1,4-dioxine |
| 2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one | 2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one | |
| 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-oxo-2-(4-phenylbutan-2-ylamino)ethyl] ester | 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-oxo-2-(4-phenylbutan-2-ylamino)ethyl] ester | |
| 3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl ester | 3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl ester | |
| 4-hydroxy-6-propan-2-ylpyrano[3,2-c]quinoline-2,5-dione | 4-hydroxy-6-propan-2-ylpyrano[3,2-c]quinoline-2,5-dione | |
| 4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamide | 4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamide | |
| 6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamide | 6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamide | |
| 6,6'-bieckol | A phlorotanin that is 1,1'-bioxanthrene substituted by 3,5-dihydroxyphenoxy groups at position 6 and 6' and hydroxy groups at positions 2, 2', 4, 4', 7, 7', 9 and 9' respectively. It is isolated from an edible marine brown alga Ecklonia cava and exhibits antioxidant activity. | 6,6'-bieckol |
| 7-amino-5-(4-ethoxy-3-methoxyphenyl)-4-oxo-3,5-dihydropyrano[2,3-d]pyrimidine-6-carbonitrile | 7-amino-5-(4-ethoxy-3-methoxyphenyl)-4-oxo-3,5-dihydropyrano[2,3-d]pyrimidine-6-carbonitrile | |
| 7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamide | 7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamide | |
| acetic acid [1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-hydroxy-3-methylbutan-2-yl] ester | acetic acid [1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-hydroxy-3-methylbutan-2-yl] ester | |
| acetosulfame | A sulfamate ester that is 1,2,3-oxathiazin-4(3H)-one 2,2-dioxide substituted by a methyl group at position 6. | acesulfame |
| anonaine | An aporphine alkaloid that exhibits anti-cancer, trypanocidal and antiplasmodial activites. | (-)-annonaine |
| bulbocapnine | An aporphine alkaloid that has been isolated from Corydalis and exhibits inhibitory activity against enzymes such as tyrosine 3-monooxygenase and diamine oxidase. | bulbocapnine |
| canadine | A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10. | canadine |
| carboxin | An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment. | carboxin |
| cimifugin | Cimifugin | |
| cinoxacin | A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections. | cinoxacin |
| decarestrictine d | Decarestrictine D | |
| dibenzo(1,4)dioxin | oxanthrene | |
| dictamnine | Dictamnine | |
| dieckol | A phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities. | dieckol |
| Dubinidine | Dubinidine | |
| eckstolonol | A phlorotannin that is [1,4]benzodioxino[2,3-a]oxanthrene substituted by hydroxy groups at positions 1, 3, 6, 9 and 11. Isolated from the brown alga Ecklonia stolonifera, it exhibits radical scavenging activity. | eckstolonol |
| ep 201 | 3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6-methylcyclo-hexanecarboxylate | |
| ethylene oxide | A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. | oxirane |
| Evoxine | Evoxine | |
| flindersiamine | Flindersiamine | |
| flindersine | Flindersine | |
| gamma-fagarine | gamma-Fagarine | |
| haplamine | 9-Methoxy-2,2-dimethyl-6H-pyrano[3,2-c]quinolin-5-one | |
| heliparvifoline | Haplopine | |
| hematoxylin | An organic heterotetracyclic compound 7,11b-dihydroindeno[2,1-c]chromene carrying five hydroxy substituents at positions 3, 4, 6a, 9 and 10. The most important and most used dye in histology, histochemistry, histopathology and in cytology. | haematoxylin |
| hemibrevetoxin b | Hemibrevetoxin B | |
| interiotherin b | A lignan with a dibenzocyclooctadiene skeleton attached to a fatty acid ester side chain. It is isolated from Kadsura interior and has been shown to exhibit anti-HIV activity. | interiotherin B |
| irilone | A hydroxyisoflavone that is 6,7-methylenedioxyisoflavone substituted by hydroxy groups at positions 5 and 4'. | irilone |
| jnj16259685 | 3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone | |
| khellin | A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. | khellin |
| khelloside | Khellol glucoside | |
| kokusaginine | Kokusaginine | |
| lamivudine | A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. | lamivudine |
| liriodenine | An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities. | liriodenine |
| LSM-31277 | LSM-31277 | |
| LSM-31434 | LSM-31434 | |
| maculine | Maculine | |
| muromonab-cd3 | An organic heteropentacyclic compound that is isolated from the marine sponge Xestospongia exigua. | xestospongin C |
| mycalamide b | Mycalamide B | |
| N-[2-(dipropylamino)ethyl]-4-methyl-2-furo[3,2-c]quinolinecarboxamide | N-[2-(dipropylamino)ethyl]-4-methyl-2-furo[3,2-c]quinolinecarboxamide | |
| oxetorone | oxetorone | |
| oxirene | oxirene | |
| oxolinic acid | A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. | oxolinic acid |
| oxycarboxin | An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-4,4-dioxo-1,4-oxathiine-3-carboxylic acid. A fungicide for the control of rust diseases on ornamentals, cereals and nursery trees as well as fairy rings on turf. | oxycarboxin |
| pinolidoxin | Pinolidoxin | |
| pr toxin | PR-toxin | |
| prim-o-glucosylcimifugin | PRIM-O-GLUCOSYLCIMIFUGIN | |
| rotundifolone | Rotundifolone | |
| schizandrin b | An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis. | (+)-schisandrin B; Deoxygomisin A |
| skimmianine | Skimmianine | |
| tirandamycin a | Tirandamycin | |
| tripdiolide | Tripdiolide |
Research
Studies (17,574)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3,322 (18.90) | 18.7374 |
| 1990's | 2,237 (12.73) | 18.2507 |
| 2000's | 5,441 (30.96) | 29.6817 |
| 2010's | 4,678 (26.62) | 24.3611 |
| 2020's | 1,896 (10.79) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,721 (8.88%) | 5.53% |
| Reviews | 1,572 (8.11%) | 6.00% |
| Case Studies | 1,576 (8.13%) | 4.05% |
| Observational | 91 (0.47%) | 0.25% |
| Other | 14,417 (74.40%) | 84.16% |