Aneurysm, Bacterial

Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.

Synonym
Aneurysm, Bacterial
Fungal Aneurysm
Aneurysm, Infected
Mycotic Aneurysm
Bacterial Aneurysms
Aneurysm, Mycotic
Infected Aneurysm
Bacterial Aneurysm

Excerpt	Reference
"Early diagnosis of a mycotic aneurysm is critical, but often unsuspected, due to the insidious onset of symptoms related to occult infection."	( Ben-Haim, S; Hawes, DR; Rooholamini, SA; Seabold, JE, 1992)
"Ruptured fungal aneurysms are difficult to treat, so fungal meningitis or sepsis must be eradicated before an aneurysm develops."	( Kobayashi, E; Komatsu, Y; Narushima, K; Nose, T; Tomono, Y, 1991)
"The diagnosis of mycotic aneurysm is often elusive, since the patient frequently has signs and symptoms of sepsis only."	( Binet, EF; Schaefer, RF; Seabold, JE, 1983)
"Strategy for mycotic aneurysm is still controversial."	( Akai, T; Sonobe, M; Sugita, K; Suzuki, K; Takahashi, S, 1995)
"Mycotic aneurysm is a rare disease."	( Daum, H; Debus, ES; Gross-Fengels, W; Imig, H; Kindel, M; Larena-Avellaneda, A, 2004)
"Coronary mycotic aneurysms are rare with a poor prognosis."	( Shah, RK; Vijayakumar, V, 2005)
"Mycotic aneurysms are associated with high mortality rates and are managed in the local setting with extra-anatomical bypass followed by ligation, exclusion and debridement of the aneurysm."	( Chia, KH; Kam, MH; Tan, SG; Toh, LK; Wong, D, 2007)
"Mycotic aneurysms are a fatal manifestation of disseminated fungal infections in immunocompromised hosts."	( Birkenbach, M; Faizer, R; Green, JS; Ustun, C; Wasko, JA, 2019)
"Mycotic aneurysm is one of the extra-intestinal manifestations of Salmonella Enteritidis infection."	( Ding, CH; Mohamed, N; Mohammed, F; Muttaqillah, NAS; Rosli, N; Wahab, AA, 2023)

Excerpt	Reference
"Although infected aneurysms have been described well before, an aneurysm infected with Bacillus cereus is rare."	( Huang, PW; Pai, CC; Tung, CB; Wu, TC, 2019)

Excerpt	Reference
"Indications for treatment were: mycotic aneurysms-3, primary aorto-enteric fistula-2 and graft infection-7."	( Bauer, E; Carrell, T; Laske, A; Olah, A; Turina, M; Vogt, M, 1992)
"Four patients with mycotic aneurysm of the extracranial carotid artery, the innominate artery, the ascending aorta, and the infrarenal aorta were treated with local implantation of antibiotic-releasing carriers after resection of the aneurysm, excision of all infected tissue, and in situ reconstruction by prosthetic graft replacement in two patients and patch plasty in two patients."	( Pasic, M; Turina, M; von Segesser, L, 1992)
"Ruptured fungal aneurysms are difficult to treat, so fungal meningitis or sepsis must be eradicated before an aneurysm develops."	( Kobayashi, E; Komatsu, Y; Narushima, K; Nose, T; Tomono, Y, 1991)
"fetus may represent a subset of infected aneurysms that can be treated successfully with an anatomically placed prosthetic graft and antibiotics."	( Eakins, JW; Maxwell, JG; Rutherford, EJ; Tackett, AD, 1989)
"Different treatments of intracranial mycotic aneurysms are finally reviewed and a therapeutic approach is discussed."	( Flament-Durand, J; Hermanus, N; Noterman, J; Rodesch, G; Thys, JP, 1987)
"Rupture of a mycotic aneurysm often occurs before the diagnosis of bacterial endocarditis is made or whilst the patient is being treated with antibiotics."	( Bamford, J; Hodges, J; Warlow, C, 1986)
"Fifty patients were treated for 52 mycotic aneurysms secondary to intravenous drug abuse."	( Johnson, JR; Ledgerwood, AM; Lucas, CE, 1983)
"Antibiotics were administered because a mycotic aneurysm was suspected."	( Akai, T; Sonobe, M; Sugita, K; Suzuki, K; Takahashi, S, 1995)
"The brain abscess and intracranial mycotic aneurysm were resolved under appropriate antibiotic therapy for eight weeks."	( Abe, H; Nakajima, N; Nakaya, M; Okimoto, M; Sato, A; Watanabe, Y, 1998)
"Thus, an infected aneurysm was effectively treated with a RFP-soaked vascular prosthesis and omentopexy."	( Hamano, K; Ikeda, Y; Ikenaga, S; Itoh, H; Mikamo, A; Takahashi, M, 2005)
"Owing to the inevitable rupture of mycotic aneurysms, the standard treatment is surgical repair with appropriate secondary antibiotics."	( Jorgensen, MS; Murray, PM; Oldenburg, WA, 2019)
"A review of endovascular cerebral mycotic aneurysm treatment with Onyx liquid embolic, N-butyl-2-cyanoacrylate (NBCA), or coil embolization has not been reported."	( Desai, B; Desai, H; Kumar, J; Park, MS; Raper, DM; Shah, S; Soldozy, S, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	92 (26.74)	23.3326
1990's	61 (17.73)	12.5806
2000's	71 (20.64)	18.1394
2010's	99 (28.78)	28.8240
2020's	21 (6.10)	9.53

Drug	Relationship Strength	Studies	Trials
citric acid, anhydrous	low	2	0
lactic acid	low	1	0
dimethyl sulfoxide	low	4	0
iodine	low	1	0
oxyquinoline	low	1	0
albendazole	low	2	0
aspirin	low	3	0
azathioprine	low	1	0
aztreonam	low	1	0
cefuroxime	low	1	0
ciprofloxacin	low	9	0
pentetic acid	low	1	0
fentanyl	low	1	0
fluconazole	low	3	0
flucytosine	low	2	0
fluorouracil	low	1	0
gentamicin	low	17	0
hydroxychloroquine	low	3	0
iohexol	low	1	0
iopromide	low	1	0
isoniazid	low	2	0
ketoconazole	low	2	0
methadone	low	1	0
methylphenidate	low	3	0
metronidazole	low	3	0
nimodipine	low	1	0
ofloxacin	low	3	0
aminosalicylic acid	low	1	0
piracetam	low	1	0
potassium chloride	low	1	0
probenecid	low	1	0
propofol	low	1	0
sulfamethizole	low	1	0
sulfamethoxazole	low	2	0
ticlopidine	low	1	0
trimethoprim	low	3	0
prednisolone	low	4	0
spironolactone	low	1	0
prednisone	low	3	0
penicillin g	low	11	0
chloramphenicol	low	4	0
cephalothin	low	3	0
kanamycin a	low	2	0
galactose	low	1	0
methicillin	low	5	0
cloxacillin	low	3	0
lactose	low	1	0
colchicine	low	1	0
oxacillin	low	2	0
ampicillin	low	11	0
mannitol	low	1	0
cytarabine	low	1	0
valine	low	1	0
penicillanic acid	low	2	0
nafcillin	low	1	0
copper gluconate	low	1	0
methamphetamine	low	1	0
erythromycin	low	2	0
bucrylate	low	1	0
ethambutol	low	1	0
vancomycin	medium	19	1
methylprednisolone hemisuccinate	low	1	0
streptomycin	low	5	0
floxacillin	low	4	0
enbucrilate	low	1	0
platinum	low	1	0
silver	medium	4	1
tantalum	low	1	0
technetium	medium	10	1
titanium	low	1	0
gadolinium	low	1	0
chlormerodrin	low	1	0
trolamine salicylate	low	4	0
cefazolin	low	5	0
amoxicillin	low	6	0
tobramycin	low	1	0
paclitaxel	low	2	0
eg 626	low	1	0
propiconazole	low	2	0
cefonicid	low	1	0
piperacillin	low	4	0
cefotiam	low	1	0
cefaclor anhydrous	low	1	0
lovastatin	low	1	0
itraconazole	low	2	0
clopidogrel	low	1	0
trimethoprim sulfamethizole	low	1	0
cephalosporin c	low	8	0
fropenem	low	1	0
triazoles	low	5	0
fluorodeoxyglucose f18	low	25	0
voriconazole	low	6	0
fibrinogen	low	1	0
dextromoramide	low	1	0
imipenem, anhydrous	low	1	0
beta-lactams	low	1	0
levofloxacin	low	2	0
moxifloxacin	low	1	0
naproxen	low	1	0
mt 0703	low	1	0
technetium tc 99m pentetate	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	6	0
elastin	low	3	0
meropenem	low	3	0
netilmicin	low	1	0
linezolid	low	1	0
resveratrol	low	1	0
cocaine	low	1	0
clindamycin	low	3	0
zithromax	low	1	0
posaconazole	low	1	0
l 743,872	low	3	0
micafungin	low	1	0
sodium acetate, anhydrous	low	1	0
stilbenes	low	1	0
buprenorphine	low	1	0
fusidic acid	low	2	0
indium oxine	low	1	0
nitinol	low	2	0
galactomannan	low	1	0
amphotericin b	low	17	0
phenylephrine hydrochloride	low	1	0
levetiracetam	low	1	0
naloxone	low	1	0
sirolimus	low	4	0
indium	low	1	0
sulfur	low	1	0
heroin	low	7	0
cefotaxime	low	5	0
gadolinium dtpa	low	1	0
mocetinostat	low	1	0
technetium tc 99m exametazime	low	2	0
indocyanine green	low	2	0
ro13-9904	low	18	0
sodium pertechnetate tc 99m	low	1	0
piperacillin, tazobactam drug combination	low	2	0
cardiovascular agents	low	1	0
mannans	low	1	0
technetium tc 99m gluceptate	low	1	0
tetracycline	low	1	0
chlortetracycline	low	1	0
technetium tc 99m sulfur colloid	low	1	0
daptomycin	low	1	0
cyclosporine	low	1	0
exudates	low	3	0
acyclovir	low	2	0
rifampin	low	32	0
valacyclovir	low	1	0

Protein Targets (1,399)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Ferritin light chain	9	0	0	9
Thymidine kinase	0	1	0	1
thioredoxin reductase	15	0	0	15
phosphopantetheinyl transferase	12	0	0	12
GLS protein	14	0	0	14
TDP1 protein	34	0	0	34
Smad3	8	0	0	8
thyroid stimulating hormone receptor	14	0	0	14
EWS/FLI fusion protein	25	0	0	25
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	29	0	0	29
activating transcription factor 6	13	0	0	13
Histone H2A.x	11	0	0	11
Bloom syndrome protein isoform 1	10	0	0	10
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lamin isoform A-delta10	25	0	0	25
Solute carrier family 22 member 1	0	3	0	4
ATP-binding cassette sub-family C member 3	0	41	0	41
Multidrug resistance-associated protein 4	0	41	0	42
Solute carrier family 22 member 6	0	9	0	10
Bile salt export pump	0	15	0	15
Bile salt export pump	0	52	0	52
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	18	0	19
Cytochrome P450 2J2	0	10	0	10
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	6	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	7	0	10
Canalicular multispecific organic anion transporter 1	0	41	0	41
Thymidine kinase	0	2	0	2
Chain A, Beta-lactamase	13	0	0	13
Luciferase	13	0	0	13
glp-1 receptor, partial	10	0	0	10
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
RAR-related orphan receptor gamma	26	0	0	26
ATAD5 protein, partial	11	0	0	11
Fumarate hydratase	7	0	0	7
GLI family zinc finger 3	30	0	0	30
AR protein	33	0	0	33
caspase 7, apoptosis-related cysteine protease	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	21	0	0	21
progesterone receptor	18	0	0	18
glucocorticoid receptor [Homo sapiens]	29	0	0	29
retinoic acid nuclear receptor alpha variant 1	28	0	0	28
retinoid X nuclear receptor alpha	20	0	0	20
estrogen-related nuclear receptor alpha	28	0	0	28
farnesoid X nuclear receptor	20	0	0	20
pregnane X nuclear receptor	26	0	0	26
estrogen nuclear receptor alpha	44	0	0	44
polyprotein	7	0	0	7
67.9K protein	10	0	0	10
peroxisome proliferator activated receptor gamma	18	0	0	18
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
caspase-3	6	0	0	6
IDH1	12	0	0	12
aryl hydrocarbon receptor	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
cellular tumor antigen p53 isoform a	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
chromobox protein homolog 1	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	25	0	0	25
histone deacetylase 9 isoform 3	4	0	0	4
heat shock protein beta-1	10	0	0	10
mitogen-activated protein kinase 1	3	0	0	3
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
geminin	31	0	0	31
Vif	0	1	0	2
peripheral myelin protein 22	11	0	0	11
survival motor neuron protein isoform d	6	0	0	6
muscleblind-like protein 1 isoform 1	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
neuropeptide S receptor isoform A	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	16	0	0	16
Interferon beta	19	0	0	19
Cellular tumor antigen p53	26	0	0	26
Integrin beta-3	3	2	0	5
Integrin alpha-IIb	3	1	0	4
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	16	0	0	16
Fatty-acid amide hydrolase 1	0	3	0	3
Inositol monophosphatase 1	2	0	0	2
ATPase family AAA domain-containing protein 5	11	0	0	11
Ataxin-2	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	13	0	0	13
Microtubule-associated protein tau	9	0	0	9
thioredoxin glutathione reductase	6	0	0	6
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Carbonic anhydrase 1	0	10	0	10
Carbonic anhydrase 2	0	10	0	10
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	6
Beta-lactamase	0	0	0	7
Beta-lactamase	0	0	0	6
apical membrane antigen 1, AMA1	4	0	0	4
Beta-lactamase	0	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	15	0	0	15
DNA polymerase kappa isoform 1	8	0	0	8
Beta-lactamase SHV-1	0	0	0	5
Beta-lactamase SHV-1	0	0	0	7
Beta-lactamase	0	0	0	7
Kappa-type opioid receptor	0	5	1	12
Solute carrier family 15 member 1	0	15	0	16
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	7
Solute carrier family 15 member 2	0	8	0	8
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	5
Solute carrier family 15 member 2	0	9	0	9
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	6
Chain A, Cruzipain	6	0	0	6
interleukin 8	12	0	0	12
peroxisome proliferator-activated receptor delta	17	0	0	17
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	29	0	0	29
Cytochrome P450 1A2	0	5	0	6
Cytochrome P450 3A4	0	21	0	23
Cytochrome P450 2D6	0	6	0	7
Cytochrome P450 2C19	0	13	0	14
Nuclear receptor ROR-gamma	9	0	0	9
Potassium voltage-gated channel subfamily H member 2	0	16	0	18
Aurora kinase B	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	7
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	2	0	6
acid sphingomyelinase	2	0	0	2
Beta-lactamase	0	1	0	6
Beta-lactamase	0	0	0	7
Metallo-beta-lactamase type 2	0	0	1	8
Metallo-beta-lactamase VIM-11	0	0	0	6
Metallo-beta-lactamase VIM-2	0	0	0	6
Beta-lactamase	0	0	0	7
Metallo-beta-lactamase	0	0	0	6
Beta-lactamase	0	1	0	6
DNA polymerase beta	3	0	0	3
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	4
Spike glycoprotein	15	0	1	16
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	0	0	7
Efflux transporter	0	1	0	4
Beta-lactamase	0	0	0	6
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	1	0	4
Class D beta-lactamase	0	0	0	5
60 kDa chaperonin	0	5	0	5
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	6
Beta-lactamase	0	0	1	5
10 kDa chaperonin	0	5	0	5
Metallo-b-lactamase	0	0	0	9
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	7
Histamine H3 receptor	0	0	0	6
Beta-lactamase class B VIM-2	0	0	1	10
Beta-lactamase VIM-1	0	0	0	7
ATP-dependent phosphofructokinase	7	0	0	7
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	24	0	0	24
cytochrome P450 2D6	11	0	0	11
glucocerebrosidase	2	0	0	2
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	3	1	4
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	1	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Adenosine receptor A1	0	2	0	2
Adenosine receptor A2a	0	3	0	3
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	6	0	6
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	10	4	1	16
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	9	1	10
Sigma non-opioid intracellular receptor 1	0	2	1	3
acetylcholinesterase	8	0	0	8
SMAD family member 2	7	0	0	7
SMAD family member 3	7	0	0	7
G	15	0	0	15
P53	2	0	0	2
thyroid stimulating hormone receptor	8	0	0	8
peripheral myelin protein 22 isoform 1	5	0	0	5
cytochrome P450 3A4 isoform 1	10	0	0	10
M-phase phosphoprotein 8	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	10	3	1	15
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
Gamma-aminobutyric acid receptor subunit beta-1	10	3	1	15
Gamma-aminobutyric acid receptor subunit delta	10	3	1	15
Gamma-aminobutyric acid receptor subunit gamma-2	10	3	1	15
Gamma-aminobutyric acid receptor subunit alpha-5	10	3	1	15
Gamma-aminobutyric acid receptor subunit alpha-3	10	3	1	15
Gamma-aminobutyric acid receptor subunit gamma-1	10	3	1	15
Gamma-aminobutyric acid receptor subunit alpha-2	10	3	1	15
Gamma-aminobutyric acid receptor subunit alpha-4	10	3	1	15
Gamma-aminobutyric acid receptor subunit gamma-3	10	3	1	15
Gamma-aminobutyric acid receptor subunit alpha-6	10	3	1	15
Gamma-aminobutyric acid receptor subunit beta-3	10	3	1	15
Gamma-aminobutyric acid receptor subunit beta-2	10	3	1	15
GABA theta subunit	10	3	1	15
Inositol hexakisphosphate kinase 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit epsilon	10	3	1	15
Protein-arginine deiminase type-4	0	12	0	12
cytochrome P450 2C9, partial	15	0	0	15
Kappa-type opioid receptor	0	6	2	9
Dihydroxyacetone phosphate acyltransferase	0	0	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
importin subunit beta-1 isoform 1	4	0	0	4
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	7	0	0	7
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	2	0	2
streptokinase A precursor	0	0	10	10
Estrogen receptor	0	0	3	3
Estrogen receptor beta	0	0	3	3
Solute carrier family 22 member 11	0	5	0	6
Solute carrier family 22 member 8	0	6	0	7
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase VIM-19	0	0	0	5
Beta-lactamase	0	0	0	4
Albumin	0	0	7	7
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase VIM-2	0	0	0	6
Solute carrier family 22 member 7	0	3	0	3
BlaVIM-1	0	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	4
Solute carrier family 22 member 7	0	4	0	5
endonuclease IV	7	0	0	7
WRN	1	0	0	1
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
flap endonuclease 1	6	0	0	6
Solute carrier family 22 member 8	0	7	0	9
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	4
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase TEM	0	2	0	6
Beta-lactamase	0	0	0	3
phosphoglycerate kinase	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
30S ribosomal protein S6	0	6	1	7
30S ribosomal protein S7	0	6	1	7
50S ribosomal protein L15	0	6	1	7
50S ribosomal protein L10	0	6	1	7
50S ribosomal protein L11	0	6	1	7
50S ribosomal protein L7/L12	0	6	1	7
50S ribosomal protein L19	0	6	1	7
50S ribosomal protein L1	0	6	1	7
50S ribosomal protein L20	0	6	1	7
50S ribosomal protein L27	0	6	1	7
50S ribosomal protein L28	0	6	1	7
50S ribosomal protein L29	0	6	1	7
50S ribosomal protein L31	0	6	1	7
50S ribosomal protein L31 type B	0	6	1	7
50S ribosomal protein L32	0	6	1	7
50S ribosomal protein L33	0	6	1	7
50S ribosomal protein L34	0	6	1	7
50S ribosomal protein L35	0	6	1	7
50S ribosomal protein L36	0	6	1	7
30S ribosomal protein S10	0	6	1	7
30S ribosomal protein S11	0	6	1	7
30S ribosomal protein S12	0	6	1	7
30S ribosomal protein S13	0	6	1	7
30S ribosomal protein S16	0	6	1	7
30S ribosomal protein S18	0	6	1	7
30S ribosomal protein S19	0	6	1	7
30S ribosomal protein S20	0	6	1	7
30S ribosomal protein S2	0	6	1	7
30S ribosomal protein S3	0	6	1	7
30S ribosomal protein S4	0	6	1	7
30S ribosomal protein S5	0	6	1	7
30S ribosomal protein S8	0	6	1	7
30S ribosomal protein S9	0	6	1	7
50S ribosomal protein L13	0	6	1	7
50S ribosomal protein L14	0	6	1	7
50S ribosomal protein L16	0	6	1	7
50S ribosomal protein L23	0	6	1	7
30S ribosomal protein S15	0	6	1	7
50S ribosomal protein L17	0	6	1	7
50S ribosomal protein L21	0	6	1	7
50S ribosomal protein L30	0	6	1	7
50S ribosomal protein L6	0	6	1	7
30S ribosomal protein S14	0	6	1	7
30S ribosomal protein S17	0	6	1	7
30S ribosomal protein S1	0	6	1	7
50S ribosomal protein L18	0	6	1	7
50S ribosomal protein L2	0	6	1	7
50S ribosomal protein L3	0	6	1	7
50S ribosomal protein L24	0	6	1	7
50S ribosomal protein L4	0	6	1	7
50S ribosomal protein L22	0	6	1	7
50S ribosomal protein L5	0	6	1	7
30S ribosomal protein S21	0	6	1	7
50S ribosomal protein L25	0	6	1	7
50S ribosomal protein L36 2	0	6	1	7
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	3	0	3
cytochrome P450 2C9 precursor	2	0	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	5	0	9
DNA gyrase subunit B	0	5	0	9
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA topoisomerase 2-alpha	0	1	1	6
DNA gyrase subunit A	0	2	0	3
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	6	0	0	6
DNA gyrase subunit B	0	5	0	7
DNA gyrase subunit A	0	6	0	8
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
thyroid hormone receptor beta isoform a	7	0	0	7
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	1	3
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
nonstructural protein 1	7	0	0	7
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2B6	0	5	1	6
Liver carboxylesterase 1	0	0	0	3
Sodium-dependent serotonin transporter	0	8	1	9
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	1	2	1	4
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	2
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	12	2	14
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium-dependent serotonin transporter	0	4	0	5
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium-dependent dopamine transporter	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	3	0	3
PAX8	0	0	0	1
pregnane X receptor	7	0	0	7
USP1 protein, partial	12	0	0	12
PPM1D protein	3	0	0	3
Thrombopoietin	2	0	0	2
estrogen receptor 2 (ER beta)	14	0	0	14
cytochrome P450 2D6 isoform 1	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C19 precursor	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Tubulin alpha-1A chain	0	2	2	5
Tubulin beta chain	0	2	2	4
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	4	3	9
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	4	3	9
ATP-dependent translocase ABCB1	0	13	0	18
Tubulin alpha-3C chain	0	4	3	9
Serine/threonine-protein kinase pim-1	0	1	1	2
ATP-dependent translocase ABCB1	0	7	0	7
Tubulin alpha-1B chain	0	4	3	9
Tubulin alpha-4A chain	0	4	3	9
Tubulin beta-4B chain	0	4	3	9
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	5	3	10
Tubulin beta-2A chain	0	4	3	9
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	4	3	9
Tubulin beta-2B chain	0	3	1	6
Tubulin alpha-3E chain	0	4	3	9
Tubulin alpha-1A chain	0	4	3	9
Similar to alpha-tubulin isoform 1	0	2	1	5
Similar to alpha-tubulin isoform 1	0	2	0	4
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	4	3	9
Tubulin beta-6 chain	0	4	3	9
Tubulin beta-2B chain	0	4	3	9
Tubulin beta-1 chain	0	4	3	9
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	1	0	2
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	1	2
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	2	0	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
60 kDa chaperonin	0	2	0	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Lanosterol 14-alpha demethylase	0	7	2	9
Multidrug and toxin extrusion protein 1	0	3	0	3
Pantothenate synthetase	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(2) dopamine receptor	0	2	0	2
Amine oxidase [flavin-containing] A	0	4	0	4
D(4) dopamine receptor	0	2	0	2
Amine oxidase [flavin-containing] B	0	3	0	3
Delta-type opioid receptor	0	4	1	6
Delta-type opioid receptor	0	4	2	6
Mu-type opioid receptor	0	4	3	7
Kappa-type opioid receptor	0	2	2	4
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	6	2	9
D(3) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	9	1	11
Mu-type opioid receptor	0	2	0	3
Mu-type opioid receptor	0	5	1	6
Sigma non-opioid intracellular receptor 1	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	2	0	4
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	3	0	3
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	4	0	4
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	3	4
Aromatase	0	7	0	7
Cytochrome P450 11B1, mitochondrial	0	3	0	3
Cytochrome P450 11B2, mitochondrial	0	3	0	3
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	2	0	2
Histone deacetylase 4	0	2	0	2
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
TAR DNA-binding protein 43	6	0	0	6
Histone deacetylase 1	0	4	0	4
Sterol 14-alpha demethylase	0	0	3	3
Sterol 14-alpha demethylase	0	2	2	4
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
14-alpha sterol demethylase	0	0	3	3
Histone deacetylase 8	0	2	1	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Skn7p	0	0	0	2
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
huntingtin isoform 2	2	0	0	2
Vpr	3	0	0	3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Canalicular multispecific organic anion transporter 1	0	2	0	2
large T antigen	0	2	0	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	6	0	6
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	2	1	3
Replicase polyprotein 1ab	0	2	1	3
Muscarinic acetylcholine receptor M1	0	1	0	1
Alpha-2B adrenergic receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	3	0	3
Muscarinic acetylcholine receptor M3	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
nuclear receptor ROR-gamma isoform 1	8	0	0	8
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	2	0	2
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
GALC protein	4	0	0	4
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Estrogen receptor beta	0	1	1	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	8	0	8
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	1	2
Substance-K receptor	0	6	0	6
UDP-glucuronosyltransferase 1A1	0	3	0	3
Thromboxane-A synthase	0	1	0	1
Histamine H2 receptor	0	2	0	2
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	2	0	2
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA primase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	7	0	7
Amine oxidase [flavin-containing] B	0	2	0	2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1S	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	8
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
15-lipoxygenase, partial	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
PINK1	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
Parkin	3	0	0	3
thyrotropin-releasing hormone receptor	2	0	0	2
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	1	0	1
Insulin receptor	0	1	0	1
Androgen receptor	0	5	0	6
Integrin alpha-L	0	1	1	2
Adenosine receptor A1	0	3	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	6	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
DNA gyrase subunit B	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Histidine decarboxylase	0	0	1	1
D(3) dopamine receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	2
Beta-2 adrenergic receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Dihydrofolate reductase	0	3	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Caspase-1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
regulator of G-protein signaling 4	2	0	0	2
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Adenosine receptor A3	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	1	0	1
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
MecA	0	1	0	1
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	2	0	3
Cholinesterase	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Botulinum neurotoxin type A	0	2	0	2
Catechol O-methyltransferase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Catechol O-methyltransferase	0	1	0	1
Alpha-synuclein	2	2	0	4
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Tyrosine-protein kinase ABL1	0	2	1	4
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	1	2
Integrin alpha-V	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Fibroblast growth factor receptor 1	0	1	1	2
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	2	0	2
Tyrosine-protein kinase Mer	0	1	1	2
Beta-tubulin	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Hsf1 protein	0	0	1	2
Sterol 14-alpha-demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
Carbonic anhydrase 4	0	3	0	3
Carbonic anhydrase 5A, mitochondrial	0	3	0	3
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Carbonic anhydrase 9	0	4	0	4
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	5	1	6
Glucocorticoid receptor	0	6	3	14
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	6	0	6
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	4	1	6
Androgen receptor	0	4	1	5
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	3	1	4
alpha-galactosidase	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Carbonic anhydrase 12	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
D(1A) dopamine receptor	1	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
ClpP	1	0	0	1
pyruvate kinase	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	0	0	1	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
POsterior Segregation	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Acetylcholinesterase	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Myc proto-oncogene protein	0	1	0	2
Transthyretin	0	0	1	1
Cytochrome P450 1A1	0	1	0	1
Tyrosine-protein kinase Lck	0	1	1	2
Cathepsin D	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Breakpoint cluster region protein	0	1	1	3
Tyrosinase	0	3	0	3
Ornithine decarboxylase	0	1	0	1
Tyrosinase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	2	4
Protein kinase C alpha type	0	0	2	2
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Endothelin receptor type B	1	0	0	1
Carbonic anhydrase 6	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Endothelin-1 receptor	1	1	0	2
Dipeptidyl peptidase 4	0	2	0	2
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Alpha-glucosidase MAL12	0	1	0	1
Cholinesterase	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Squalene synthase	0	1	0	1
Transcription factor p65	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	3
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
Carbonic anhydrase 13	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Carbonic anhydrase 15	0	1	0	1
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Carbonic anhydrase 14	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Cyclin-dependent kinase 1	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	1	2
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Free fatty acid receptor 3	0	0	1	1
Carbonic anhydrase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	2	0	2
exodeoxyribonuclease V subunit RecB	0	2	0	2
exodeoxyribonuclease V subunit RecC	0	2	0	2
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Protease	0	1	1	2
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Collagenase 3	0	1	0	1
Protein Rev	0	0	1	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
dopamine D1 receptor	1	0	0	1
NFKB1 protein, partial	1	0	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(8)

Research Excerpts

Overview

Context

Treatment

Research

Studies (344)

Protein Targets (1,399)

Aneurysm, Bacterial

Synonyms(8)

Research Excerpts

Overview

Context

Treatment

Research

Studies (344)

Drugs Studied (161)

Protein Targets (1,399)