A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2).
ChEBI ID: 17102
| Member | Definition | Role |
|---|---|---|
| acephate | A phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. | acephate |
| azetepa | azatepa | |
| fosaprepitant | A morpholine derivative that is the (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl ether of (3-{[(2R,3S)-3-(4-fluorophenyl)-2-hydroxymorpholin-4-yl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid. | fosaprepitant |
| hempa | hexamethylphosphoric triamide | |
| metepa | Tris(2-methyl-1-aziridinyl)phosphine oxide | |
| methamidophos | An organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate. | methamidophos |
| meturedepa | meturedepa | |
| mipafox | Mipafox | |
| phosphoglycocyamine | A guanidinoacetate having a phospho group attached to the primary amino part of the guanidine moiety. | phosphoguanidinoacetic acid |
| tetraisopropylpyrophosphamide | Diphosphoramide, N,N',N'',N'''-tetrakis(1-methylethyl)- | |
| triethylenephosphoramide | Tris(1-aziridinyl)phosphine oxide |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 251 (24.88) | 18.7374 |
| 1990's | 166 (16.45) | 18.2507 |
| 2000's | 241 (23.89) | 29.6817 |
| 2010's | 266 (26.36) | 24.3611 |
| 2020's | 85 (8.42) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 52 (4.60%) | 5.53% |
| Reviews | 41 (3.63%) | 6.00% |
| Case Studies | 27 (2.39%) | 4.05% |
| Observational | 3 (0.27%) | 0.25% |
| Other | 1,008 (89.12%) | 84.16% |