Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom.
ChEBI ID: 35284
| Member | Definition | Role |
|---|---|---|
| 3-(2,2,2-trimethylhydrazine)propionate | An ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes. | meldonium |
| calcium crimson | calcium crimson | |
| cocamidopropyl betaine | An ammonium betaine in which the the ammonium nitrogen is substituted by two methyl groups and a lauramidopropyl group. It is the major (>50%) component of cocamidopropyl betaine. | lauramidopropyl betaine |
| nicotinate ribonucleoside | Conjugate base of D-ribosylnicotinic acid. | D-ribosylnicotinate |
| perifosine | A phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group. | perifosine |
| thiamine triphosphate | An ammonium betaine that is the conjugate base of thiamine(1+) triphosphate arising from the deptoronation of one of the hydroxy groups of the terminal phosphate group. | thiamine(1+) triphosphate(1-) |
| zwittergent 3-12 | An ammonium betaine in which the ammonium nitrogen is substituted by dodecyl, 3-sulfatopropyl and two methyl groups. | lauryl sulfobetaine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 35 (5.66) | 18.7374 |
| 1990's | 69 (11.17) | 18.2507 |
| 2000's | 172 (27.83) | 29.6817 |
| 2010's | 274 (44.34) | 24.3611 |
| 2020's | 68 (11.00) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 78 (11.27%) | 5.53% |
| Reviews | 35 (5.06%) | 6.00% |
| Case Studies | 25 (3.61%) | 4.05% |
| Observational | 1 (0.14%) | 0.25% |
| Other | 553 (79.91%) | 84.16% |