A succinate ester in which only one of the carboxy groups of succinic acid has been esterified.
ChEBI ID: 138979
| Member | Definition | Role |
|---|---|---|
| alpha-tocopherol succinate | tocopherol succinate | |
| artesunate | An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria. | artesunate |
| butoctamide succinate | Butoctamide hydrogen succinate | |
| chloramphenicol succinate | Chloramphenicol succinate | |
| cholesteryl succinate | A dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. | cholesteryl hemisuccinate |
| estriol succinate | estriol succinate | |
| hydrocortisone hemisuccinate | A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone). | hydrocortisone succinate |
| methylprednisolone hemisuccinate | methylprednisolone succinate | |
| monoethyl succinate | 4-Ethoxy-4-oxobutanoic acid | |
| monomethyl succinate | A dicarboxylic acid monoester that is succinic acid in which one of the carboxy groups has been converted to its methyl ester. | monomethyl succinate |
| o-succinylhomoserine | The O-succinyl derivative of L-homoserine. | O-succinyl-L-homoserine |
| prednisolone hemisuccinate | A hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. | prednisolone succinate |
| progesterone 11-hemisuccinate, (11alpha)-isomer | A steroid ester that is the O-succinoyl derivative of 11alpha-hydroxyprogesterone. | 11alpha-hydroxyprogesterone hemisuccinate |
| sarpogrelate | sarpogrelate | |
| suxibuzone | A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses. | suxibuzone |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 466 (28.04) | 18.7374 |
| 1990's | 309 (18.59) | 18.2507 |
| 2000's | 376 (22.62) | 29.6817 |
| 2010's | 437 (26.29) | 24.3611 |
| 2020's | 74 (4.45) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 165 (9.16%) | 5.53% |
| Reviews | 58 (3.22%) | 6.00% |
| Case Studies | 252 (13.98%) | 4.05% |
| Observational | 4 (0.22%) | 0.25% |
| Other | 1,323 (73.42%) | 84.16% |