Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.
| Member | Definition | Class |
|---|
| beryllium | Alkaline earth metal atom with atomic number 4. | beryllium atom; beryllium(0) |
| caffeine | A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. | caffeine |
| cimetidine | A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach. | cimetidine |
| fentanyl | A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid. | fentanyl |
| lucanthone | A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone. | lucanthone |
| medroxyprogesterone acetate | An acetate ester resulting from the formal condensation of the 17alpha-hydroxy group of medroxyprogesterone with the carboxy group of acetic acid. A widely used progestin in menopausal hormone therapy and in progestogen-only birth control. | medroxyprogesterone acetate |
| pinellic acid | A trihydroxyoctadecenoic acid with hydroxy groups at positions C-9, -12, and 13, and an E (cis) double bond at position 10. | pinellic acid |
| thymoquinone | A member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity. | thymoquinone |
| triacetin | A triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. | triacetin |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 67.9K protein | Vaccinia virus | Potency | 5.0119 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 50.7151 | 2 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 13.0658 | 12 | 37 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 65.7908 | 2 | 2 |
| arylsulfatase A | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 29.0810 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 21.6592 | 1 | 2 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 4.7755 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 44.2633 | 1 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 26.6320 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 28.7968 | 2 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 8.4465 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 18.9389 | 2 | 6 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.0078 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0235 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 20.0506 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 22.1209 | 8 | 19 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 27.5806 | 6 | 17 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 6.9530 | 1 | 8 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 24.3958 | 4 | 6 |
| G | Vesicular stomatitis virus | Potency | 8.4465 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 18.9389 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 8.8049 | 2 | 7 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 18.7930 | 2 | 6 |
| GLS protein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 3.9854 | 5 | 13 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 18.4152 | 1 | 3 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 24.9618 | 1 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 8.4465 | 1 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 8.4465 | 1 | 4 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 19.1060 | 2 | 5 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 25.3248 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 1.1294 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 40.5334 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 33.5875 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0623 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 7.9433 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 27.8865 | 3 | 8 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 0.2214 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 26.0952 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 8.9223 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 15.8489 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 1.2589 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 58.3290 | 2 | 4 |
| Parkin | Homo sapiens (human) | Potency | 40.8708 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 2.2794 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 26.4222 | 2 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 21.8750 | 5 | 7 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 60.7690 | 1 | 3 |
| PINK1 | Homo sapiens (human) | Potency | 40.8708 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 2.2387 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 26.2123 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 6.5323 | 3 | 7 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 2.4362 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 5.9707 | 2 | 5 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.2375 | 2 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 46.3605 | 3 | 8 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.0782 | 4 | 8 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 6.8583 | 2 | 3 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 6.8583 | 2 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 10.0000 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 8.9672 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 18.0254 | 2 | 7 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 12.1221 | 2 | 6 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0014 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 11.2610 | 5 | 5 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 25.1900 | 2 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 21.0163 | 3 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 18.4152 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 1.1970 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 7.2500 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 113.5000 | 2 | 2 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | Ki | 100.0000 | 5 | 5 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 35.4333 | 15 | 15 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 37.5909 | 30 | 33 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 20.4720 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2a | Cavia porcellus (domestic guinea pig) | Ki | 50.0000 | 3 | 3 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 20.5069 | 21 | 21 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 160.9033 | 25 | 30 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 26.7211 | 19 | 19 |
| Adenosine receptor A2b | Mus musculus (house mouse) | Ki | 23.0000 | 1 | 1 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 35.3050 | 15 | 20 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 34.9750 | 12 | 12 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 56.6667 | 6 | 6 |
| Aldehyde oxidase | Homo sapiens (human) | Ki | 155.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C1 | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | IC50 | 4.0405 | 2 | 2 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 1.4059 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 5.4620 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 2,468.4873 | 3 | 3 |
| Androgen receptor | Homo sapiens (human) | IC50 | 0.0061 | 2 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2790 | 2 | 3 |
| Androgen receptor | Homo sapiens (human) | Ki | 0.0029 | 5 | 5 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 0.0048 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 39.1250 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 50.0000 | 4 | 4 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 364.5286 | 3 | 7 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 14,000.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | IC50 | 747.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 28,500.0000 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 28,500.0000 | 1 | 2 |
| Caspase-1 | Homo sapiens (human) | IC50 | 1.0800 | 1 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Chain A, Chitinase | Clonostachys rosea | Ki | 19,700.0000 | 1 | 1 |
| Chain A, Glycogen Phosphorylase | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 1 |
| Chitotriosidase-1 | Homo sapiens (human) | IC50 | 363.0000 | 1 | 2 |
| Cholinesterase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 77.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 507.5000 | 2 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 21.0000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 26.2000 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.5540 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 0.3092 | 2 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 5.3294 | 3 | 3 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0122 | 4 | 5 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.8025 | 2 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.5690 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.6117 | 2 | 3 |
| DNA-(apurinic or apyrimidinic site) endonuclease | Homo sapiens (human) | IC50 | 5.0000 | 2 | 2 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 1 |
| Endochitinase B1 | Aspergillus fumigatus | IC50 | 363.0000 | 1 | 2 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 0.9240 | 2 | 2 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 0.9240 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 0.0130 | 3 | 3 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 0.0124 | 6 | 6 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 1 |
| Glycogen phosphorylase, liver form | Rattus norvegicus (Norway rat) | IC50 | 648.0000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 159.1933 | 13 | 15 |
| Glycogen phosphorylase, muscle form | Rattus norvegicus (Norway rat) | IC50 | 182.0000 | 1 | 1 |
| Guanine deaminase | Homo sapiens (human) | Ki | 10.2000 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 147.9110 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 1.0200 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 4.1460 | 8 | 9 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.3020 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 4.8321 | 5 | 7 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 5.8930 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 1.5800 | 1 | 1 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0122 | 4 | 5 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.1965 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.1965 | 1 | 1 |
| Mineralocorticoid receptor | Homo sapiens (human) | IC50 | 1.1970 | 3 | 3 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0031 | 1 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 0.0058 | 3 | 3 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1888 | 6 | 7 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0059 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 0.0030 | 6 | 6 |
| Mu-type opioid receptor | Mus musculus (house mouse) | Ki | 0.0059 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0734 | 5 | 8 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 3.0333 | 3 | 3 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 39.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 96.1667 | 1 | 3 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | IC50 | 18.6000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3,630.0000 | 1 | 1 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 1.8197 | 1 | 1 |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | IC50 | 50.4100 | 2 | 2 |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | IC50 | 50.4100 | 2 | 2 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 2.5081 | 4 | 4 |
| Progesterone receptor | Homo sapiens (human) | Ki | 0.0005 | 8 | 8 |
| Renin | Homo sapiens (human) | Ki | 15.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 100.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 100.0000 | 1 | 1 |
| Serine-protein kinase ATM | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | IC50 | 1,100.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 2.1800 | 1 | 1 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 14.7200 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | IC50 | 4.9730 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 0.3540 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 2.4743 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 0.5900 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 329.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 5.7000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 98.3900 | 3 | 3 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 166.0000 | 1 | 1 |
| Solute carrier family 22 member 11 | Homo sapiens (human) | IC50 | 2,000.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 8.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 373.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 57.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 103.7000 | 2 | 2 |
| Solute carrier family 22 member 4 | Rattus norvegicus (Norway rat) | IC50 | 1,500.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 492.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | IC50 | 2,000.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 1,000.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | IC50 | 92.4000 | 1 | 1 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | IC50 | 166.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | Ki | 46.8000 | 1 | 1 |