An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to one other carbon and one hydrogen.
| Member | Definition | Role |
|---|
| 11-hydroxy-9,12-octadecadienoic acid | A HODE that is linoleic acid carrying a single hydroxy substituent at position 11. | (9Z,12Z)-11-hydroxyoctadecadienoic acid |
| 14,15-dihydroxyeicosatrienoic acid | A DHET obtained by formal dihydroxylation across the 14,15-double bond of arachidonic acid. | (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoic acid |
| 16,16-dimethylprostaglandin e2 | A prostanoid that is prostaglandin E2 in which both of the hydrogens at position 16 have been replaced by methyl groups. A synthetic analogue of prostaglandin E2, it is a potent inhibitor of pancreatic function and growth of experimental tumors. It also protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. | 16,16-dimethylprostaglandin E2 |
| 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid | A hydroxydocosahexaenoic acid that consists of 4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid bearing an additional 17-hydroxy substituent. | (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid |
| 4-hydroxyretinal | A retinoid that is all-trans-retinal carrying a hydroxy substituent at position 4 on the cyclohexenyl ring. | all-trans-4-hydroxyretinal |
| 4-hydroxyretinoic acid | A retinoid that consists of all-trans-retinoic acid bearing a hydroxy substituent at position 4 on the cyclohexenyl ring. | all-trans-4-hydroxyretinoic acid |
| 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid | An icosanoid that is (6E,8Z,11Z,13E)-icosatetraenoic acid substituted at positions 5 and 15 by oxo and hydroxy groups respectively. | (6E,8Z,11Z,13E,15S)-15-hydroxy-5-oxoicosatetraenoic acid |
| beraprost | An organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist which is approved to treat pulmonary arterial hypertension in Asia. | beraprost |
| fostriecin | A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines. | fostriecin |
| hawkinsin | A cysteine derivative that is cysteine in which the thiol group is substituted by a [2-(carboxymethyl)-2,5-dihydroxycyclohex-3-en-1-yl]sulfanediyl group. Hawkinsinuria is an inherited disorder which is characterized by the inability to break down the amino acid tyrosine. This results in the finding of certain metabolites in the urine, such as hawkinsin. | hawkinsin |
| laulimalide | A macrolide with formula C30H42O7 that is isolated from the marine sponges, Cacospongia mycofijiensis and Hyattella sp. | laulimalide |
| piericidin a | A member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductase | piericidin A |
| protectin d1 | A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1 | protectin D1 |
| resolvin d2 | A member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer). | resolvin D2 |
| resolvin d3 | A member of the class of resolvins that is (5Z,7E,9E,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 11 and 17 (the 4S,11R,17S-stereoisomer). | resolvin D3 |
| resolvin D4 | A member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17S-stereoisomer). | resolvin D4 |
| resolvin e2 | A member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18R stereoisomer). | resolvin E2 |