An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid.
ChEBI ID: 26666
| Member | Definition | Role |
|---|---|---|
| 2-ethylhydracrylic acid | A branched-chain saturated fatty acid that is butanoic acid substituted by a hydroxymethyl group at position 2. It is a metabolite derived from the isoleucine metabolism. | 2-ethylhydracrylic acid |
| 2-hydroxy-3-methylvaleric acid | A branched-chain fatty acid that is 3-methylpentanoic acid carrying a hydroxy substitutent at position 2. | 2-hydroxy-3-methylpentanoic acid |
| 2-methylvaleric acid | A methyl-branched fatty acid that is pentanoic acid which carries a methyl group at position 2. | 2-methylvaleric acid |
| alpha-ketobutyric acid | A 2-oxo monocarboxylic acid that is the 2-oxo derivative of butanoic acid. | 2-oxobutanoic acid |
| beta-hydroxyvaleric acid | A short-chain fatty acid that is valeric acid in which one of the methylene hydrogens at position 3 has been replaced by a hydroxy group. | 3-hydroxypentanoic acid |
| isovaleric acid | A C5, branched-chain saturated fatty acid. | isovaleric acid |
| n-pentanoic acid | A straight-chain saturated fatty acid containing five carbon atoms. | valeric acid |
| pivalic acid | A branched, short-chain fatty acid composed of propanoic acid having two methyl substituents at the 2-position. | pivalic acid |
| propiolic acid | A terminal acetylenic compound that is a 3-carbon, straight-chain, monounsaturated fatty acid having one acetylenic bond. | propynoic acid |
| propionic acid | A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group. | propionic acid |
| senecioic acid | A methyl-branched fatty acid that is but-2-enoic acid bearing a methyl substituent at position 3. | 3-methylbut-2-enoic acid |
| trans-3-methyl-2-hexenoic acid | A monounsaturated fatty acid that is (2E)-hexenoic acid in which the hydrogen at position 3 has been replaced by a methyl group. A malodourous component in the sweat of schizophrenics. | (2E)-3-methylhex-2-enoic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 531 (18.15) | 18.7374 |
| 1990's | 540 (18.46) | 18.2507 |
| 2000's | 712 (24.34) | 29.6817 |
| 2010's | 839 (28.68) | 24.3611 |
| 2020's | 303 (10.36) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 74 (2.36%) | 5.53% |
| Reviews | 77 (2.46%) | 6.00% |
| Case Studies | 117 (3.74%) | 4.05% |
| Observational | 3 (0.10%) | 0.25% |
| Other | 2,859 (91.34%) | 84.16% |