Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
| Member | Definition | Role |
|---|
| (5-Phenyl-1,2,4-triazol-3-yl)urea | | (5-Phenyl-1,2,4-triazol-3-yl)urea |
| (5S)-1-(4-cyclohexylbutyl)-5-phenyl-4,5-dihydroimidazol-2-amine | | (5S)-1-(4-cyclohexylbutyl)-5-phenyl-4,5-dihydroimidazol-2-amine |
| 1-(1-adamantyl)-3-[1-(phenylmethyl)-4-pyrazolyl]urea | | 1-(1-adamantyl)-3-[1-(phenylmethyl)-4-pyrazolyl]urea |
| 1-(3-methoxyphenyl)-3-(4-phenylbutyl)urea | | 1-(3-methoxyphenyl)-3-(4-phenylbutyl)urea |
| 1-[(2-ethyl-4-hydroxy-4-methyl-1-oxopentyl)amino]-3-phenylthiourea | | 1-[(2-ethyl-4-hydroxy-4-methyl-1-oxopentyl)amino]-3-phenylthiourea |
| 1-amino-1-phenylmethyl phosphonic acid | A member of the class of phosphonic acids that is phosphonic acid having a amino(phenyl)methyl group attached to the phosphorus. | 1-amino-1-phenylmethyl phosphonic acid |
| 1-amino-3-[3-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea | | 1-amino-3-[3-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea |
| 1-cyclohexyl-3-(2-phenylethyl)urea | | 1-cyclohexyl-3-(2-phenylethyl)urea |
| 1-ethyl-3-[[[(phenylmethyl)amino]-sulfanylidenemethyl]amino]thiourea | | 1-ethyl-3-[[[(phenylmethyl)amino]-sulfanylidenemethyl]amino]thiourea |
| 1-hydroxy-1-phenyl-2-propanone | A secondary alpha-hydroxy ketone that is benzene which is substituted by a 1-hydroxy-2-oxopropyl group at position 1. | 1-hydroxy-1-phenylpropan-2-one |
| 1-hydroxy-5-nitro-N-(2-phenylethyl)-4-spiro[benzimidazole-2,1'-cyclohexane]imine | | 1-hydroxy-5-nitro-N-(2-phenylethyl)-4-spiro[benzimidazole-2,1'-cyclohexane]imine |
| 1-hydroxy-5,5-dimethyl-2-phenyltetrahydro-4H-imidazole-4-thione | | 1-hydroxy-5,5-dimethyl-2-phenyltetrahydro-4H-imidazole-4-thione |
| 1-phenylcyclohex-1-ene | | 3-cyclohexen-1-yl-Benzene |
| 1,1,1,2,2-pentafluoro-7-phenylheptan-3-one | | FKGK 11 |
| 1,3-bis(2-phenylethyl)thiourea | | 1,3-bis(2-phenylethyl)thiourea |
| 1,4-diethylbenzene | | 1,4-Diethylbenzene |
| 2-(2-furanyl)-3,5-dimethyl-4-oxido-6-phenylpyrazin-1-ium 1-oxide | | 2-(2-furanyl)-3,5-dimethyl-4-oxido-6-phenylpyrazin-1-ium 1-oxide |
| 2-(2-phenylethyl)chromone | A member of the class of chromones that is chromone which is substituted by a 2-phenylethyl group at position 2. It is found in agarwood, a fragrant resinous heartwood obtained from certain trees in the genus Aquilaria. | 2-(2-phenylethyl)chromone |
| 2-(4-pentylphenyl)acetic acid | | 2-(4-pentylphenyl)acetic acid |
| 2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile | | 2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile |
| 2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile | | 2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile |
| 2-[1-[2-oxo-2-[(4-thiophen-2-ylphenyl)methylamino]ethyl]cyclohexyl]acetic acid | | 2-[1-[2-oxo-2-[(4-thiophen-2-ylphenyl)methylamino]ethyl]cyclohexyl]acetic acid |
| 2-[6-amino-5-cyano-4-(4-ethylphenyl)-2,4-dihydropyrano[2,3-c]pyrazol-3-yl]acetic acid methyl ester | | 2-[6-amino-5-cyano-4-(4-ethylphenyl)-2,4-dihydropyrano[2,3-c]pyrazol-3-yl]acetic acid methyl ester |
| 2-acetyl-6-amino-8-(2-phenylethyl)-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile | | 2-acetyl-6-amino-8-(2-phenylethyl)-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile |
| 2-aminobenzenesulfonamide | | 2-aminobenzenesulfonamide |
| 2-cyanophenol | | 2-Cyanophenol |
| 2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1,1-dimethyl-3-pyrrolidin-1-iumyl) ester | | 2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1,1-dimethyl-3-pyrrolidin-1-iumyl) ester |
| 2-Oxo-4-phenylbutyric acid | | 2-Oxo-4-phenylbutyric acid |
| 2-phenylbutyric acid | A monocarboxylic acid that is butyric acid substituted by a phenyl group at position 2. | 2-phenylbutyric acid |
| 2-phenylcyclopropan-1-amine | A member of the class of cyclopropanes carrying amino and phenyl substituents at positions 1 and 2 respectively. | 2-phenylcyclopropan-1-amine |
| 2-phenylpropanol | | 2-Phenyl-1-propanol |
| 2,6-dimethoxybenzoic acid | | 2,6-Dimethoxybenzoic acid |
| 3-(4-ethyl-5-methyl-3-thiophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | | 3-(4-ethyl-5-methyl-3-thiophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione |
| 3-(4-nitrophenyl)-N-(4-phenylbutyl)-5-(phenylmethyl)-4,6-dihydro-3aH-pyrrolo[3,4-d]isoxazole-6a-carboxamide | | 3-(4-nitrophenyl)-N-(4-phenylbutyl)-5-(phenylmethyl)-4,6-dihydro-3aH-pyrrolo[3,4-d]isoxazole-6a-carboxamide |
| 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid | | Dihydrosinapic acid |
| 3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline | | 3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline |
| 3-[di(propan-2-yl)phosphorylmethyl]benzonitrile | | 3-[di(propan-2-yl)phosphorylmethyl]benzonitrile |
| 3-Hydroxy-alpha-methyl-DL-tyrosine | | 3-Hydroxy-alpha-methyl-DL-tyrosine |
| 3-phenyl-3-(1-tetrazolyl)propanoic acid | | 3-phenyl-3-(1-tetrazolyl)propanoic acid |
| 3-phenylbutyric acid | A monocarboxylic acid that is butanoic acid substituted by a phenyl group at position 3. | 3-phenylbutyric acid |
| 3-phenylpropanal | A benzene which is substituted by a 3-oxopropyl group at position 1. | 3-phenylpropanal |
| 3-phenylpropionic acid | A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group. | 3-phenylpropionic acid |
| 3-phenylpropyl isothiocyanate | | 1-Isothiocyanato-3-phenylpropane |
| 3-phenylpropylamine | A phenylalkylamine that is benzene in which one of the hydrogens is substituted by a 3-aminopropyl group. | 3-phenylpropylamine |
| 3,5-dihydroxyphenylpropionic acid | | 3-(3,5-dihydroxyphenyl)propionic acid |
| 3,5-dimethyl-N-(2-phenylethyl)-N-(phenylmethyl)-4-isoxazolesulfonamide | | 3,5-dimethyl-N-(2-phenylethyl)-N-(phenylmethyl)-4-isoxazolesulfonamide |
| 3,6-dibenzyl-1,2-dihydro-1,2,4,5-tetraazine | | 3,6-dibenzyl-1,2-dihydro-1,2,4,5-tetraazine |
| 4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | | 4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione |
| 4-(1H-imidazol-1-ylmethyl)benzonitrile | | 4-(1H-imidazol-1-ylmethyl)benzonitrile |
| 4-(2-furanylmethyl)-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione | | 4-(2-furanylmethyl)-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione |
| 4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamide | | 4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamide |
| 4-(benzylsulfanyl)thieno[2,3-d]pyrimidine | A thienopyrimidine that is thieno[2,3-d]pyrimidine which is substituted at position 4 by a benzylsulfanediyl group. | 4-(benzylsulfanyl)thieno[2,3-d]pyrimidine |
| 4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | | 4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione |
| 4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile | | 4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile |
| 4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile | | 4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile |
| 4-amino-N-(4-ethoxyphenyl)benzenesulfonamide | | 4-amino-N-(4-ethoxyphenyl)benzenesulfonamide |
| 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease. | TDZD-8 |
| 4-butyl-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione | | 4-butyl-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione |
| 4-butyl-4-(hydroxymethyl)-1,2-diphenylpyrazolidine-3,5-dione | | 4-butyl-4-(hydroxymethyl)-1,2-diphenylpyrazolidine-3,5-dione |
| 4-chloro-5-sulfamoylanthranilic acid | | 2-amino-4-chloro-5-sulfamoylbenzoic acid |
| 4-methyl-1-phenylpentan-2-ol | | 4-Methyl-1-phenyl-2-pentanol |
| 4-phenyl-3-furoxancarbonitrile | A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation. | 4-phenyl-3-furoxancarbonitrile |
| 4-phenyl-3H-thiazole-2-thione | | 4-phenyl-3H-thiazole-2-thione |
| 4-phenylbutyl isothiocyanate | | 1-Isothiocyanato-4-phenylbutane |
| 4-phenylbutylamine | A phenylalkylamine that is benzene in which one of the hydrogens is substituted by a 4-aminobutyl group. | 4-phenylbutylamine |
| 4,5-diphenyl-1,2,3-triazole | A member of the class of triazoles that is 2H-1,2,3-triazole carrying two phenyl substituents at positions 4 and 5. | 4,5-diphenyl-1,2,3-triazole |
| 5-(4-phenylbutoxy)psoralen | A member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM). | psora 4 |
| 5-[4-(2-furylcarbonyl)piperazino]-5-oxo-3-phenylpentanoic acid | | 5-[4-(2-furylcarbonyl)piperazino]-5-oxo-3-phenylpentanoic acid |
| 5-amino-2-(diethylamino)-N-(2-methoxyphenyl)benzenesulfonamide | | 5-amino-2-(diethylamino)-N-(2-methoxyphenyl)benzenesulfonamide |
| 5-ethyl-1-(phenylmethyl)-1,3,5-triazinane-2-thione | | 5-ethyl-1-(phenylmethyl)-1,3,5-triazinane-2-thione |
| 5-Methyl-1-phenyl-3-hexanyl sulfamate | | 5-Methyl-1-phenyl-3-hexanyl sulfamate |
| 5-methyl-2-phenyl-5-(2-phenylethyl)-1,2,4-triazolidine-3-thione | | 5-methyl-2-phenyl-5-(2-phenylethyl)-1,2,4-triazolidine-3-thione |
| 5-methyl-5-pentyl-2-phenyl-1,2,4-triazolidine-3-thione | | 5-methyl-5-pentyl-2-phenyl-1,2,4-triazolidine-3-thione |
| 5-phenylvaleric acid | A monocarboxylic acid that is valeric acid substituted by a phenyl group at the delta-position. | 5-phenylpentanoic acid |
| 6-(2-phenylethyl)-3-(phenylmethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | | 6-(2-phenylethyl)-3-(phenylmethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole |
| 8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thione | | 8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thione |
| 9-oxo-N-(1-phenylethyl)-3-bicyclo[3.3.1]nonanecarboxamide | | 9-oxo-N-(1-phenylethyl)-3-bicyclo[3.3.1]nonanecarboxamide |
| 9,10-bis(phenylethynyl)anthracene | | 9,10-bis(phenylethynyl)anthracene |
| acetyl sulfisoxazole | | sulfisoxazole acetyl |
| alpha-Cyclohexylmandelic acid | | alpha-Cyclohexylmandelic acid |
| alpha-methylphenylalanine | | alpha-Methylphenylalanine |
| aminorex | | aminorex |
| amn082 | A diamine that is ethane-1,2-diamine in which both amino groups are substituted by diphenylmethyl groups. It is an allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7). | N,N'-bis(diphenylmethyl)ethane-1,2-diamine |
| bathophenanthroline | A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two phenyl substituents at positions 4 and 7. | 4,7-diphenyl-1,10-phenanthroline |
| bay 11-7085 | A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB. | BAY11-7085 |
| beclamide | | beclamide |
| bencyclane | | bencyclane |
| bensulide | | Bensulide |
| benzal chloride | | Benzal chloride |
| benzamidine | A carboxamidine that is benzene carrying an amidino group. | benzamidine |
| benzene | A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. | benzene |
| benzonitrile | A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group. | benzonitrile |
| benzotrichloride | An organochlorine compound that is toluene in which all three hydrogens of the methyl group have been replaced by chlorines. It is used as an intermediate in organic synthesis and dye chemistry. | (trichloromethyl)benzene |
| benzoyl chloride | An acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals. | benzoyl chloride |
| benzyl cyanide | A nitrile that is acetonitrile where one of the methyl hydrogens is substituted by a phenyl group. | phenylacetonitrile |
| benzyl d-glucopyranoside | A beta-D-glucoside that is beta-D-glucopyranose in which the hydroxy group at position 1R is substituted by a benzyloxy group. | benzyl beta-D-glucopyranoside |
| benzyl isothiocyanate | | benzyl isothiocyanate |
| benzylhydrochlorothiazide | | Benzylhydrochlorothiazide |
| benzylphosphonic acid | | Benzylphosphonic acid |
| biphenylacetylene | An arylacetylene that is acetylene in which the hydrogens are replaced by phenyl groups. | biphenylacetylene |
| bitoscanate | | bitoscanate |
| bm 567 | | BM 567 |
| bms 214662 | A member of the class of benzodiazepines that is 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine substituted by (1H-imidazol-5-yl)methyl, benzyl, (thiophen-2-yl)sulfonyl, and cyano groups at positions 1, 3R, 4 and 7, respectively. It is a potent inhibitor of farnesyltransferase (IC50 = 1.35nM) which was under clinical development for the treatment of solid tumors. | BMS-214662 |
| bromfenacoum | | Brodifacoum |
| cafenstrole | | cafenstrole |
| caramiphen | | caramiphen |
| carbetapentane | | 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester |
| carbidopa | | 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
| carbutamide | | carbutamide |
| carlina oxide | | Carlina oxide |
| cetraxate | | 3-[4-[[4-(aminomethyl)cyclohexyl]-oxomethoxy]phenyl]propanoic acid |
| chlorobactene | A carotenoid that is 1,2,4-trimethylmenzene in which the hydrogen at position 3 has been replaced by an all-trans-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaen-1-yl group. Found in photosynthetic green bacteria. | chlorobactene |
| chlorpropham | A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid. | chlorpropham |
| cimaterol | | 2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile |
| clobutinol | | 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-2-butanol |
| clofilium | | Clofilium |
| clorsulon | | 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide |
| cyanophenphos | | Cyanofenphos |
| cycloadiphenine | | 2-cyclohexyl-2-phenylacetic acid 2-(diethylamino)ethyl ester |
| cyclodrine | | cyclodrine |
| desethyloxybutynin | | N-desethyloxybutynin |
| dibenzo-18-crown-6 | A crown ether that is 18-crown-6 ortho-fused to two benzene rings at positions 8-9 and 17-18. | dibenzo-18-crown-6 |
| didesmethylcitalopram | | Didemethylcitalopram |
| difenacoum | | Difenacoum |
| dioxacarb | | Dioxacarb |
| diphenidol | A tertiary alcohol that is butan-1-ol substituted by two phenyl groups at position 1 and a piperidin-1-yl group at position 4. | diphenidol |
| diphenyl | A benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops. | biphenyl |
| diphenyl disulfide | | Diphenyl disulfide |
| DPI2 | A thiazolidinone that is 2-sulfanylidene-1,3-thiazolidin-4-one substituted by 3-{[3-(morpholin-4-yl)propyl]amino}-3-oxopropyl and 4-ethylbenzylidene groups at positions 3 and 5, respectively. It is a ferroptosis inducer. | DPI2 |
| emopamil | | Emopamil |
| ethyl phenylacetate | | Ethyl phenylacetate |
| fenestrel | | Fenestrel |
| fenipentol | | Fenipentol |
| flocoumafen | | Flocoumafen |
| forasartan | A member of the class of pyridines that is pyridine which is substituted at positions 2 and 5 by o-(tetrazol-5-yl)phenyl and (3,5-dibutyl-1,2,4-triazol-1-yl)methyl groups, respectively. It is a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors, used for the treatment of hypertension. | forasartan |
| fukiic acid | | Fukiic acid |
| gallopamil | | Gallopamil |
| gluconasturtiin | An aralkylglucosinolic acid that consists of 1-thio-beta-D-glucopyranose attached to a 3-phenyl-N-(sulfooxy)propanimidoyl group at the anomeric sulfur. | gluconasturtiin |
| glucotropeolin | An aralkylglucosinolic acid that consists of 1-thio-beta-D-glucopyranose attached to a 2-phenyl-N-(sulfooxy)ethanimidoyl group at the anomeric sulfur. | glucotropeolin |
| glybuthiazol | | glybuthiazol |
| gsk2879552 | A member of the class of piperidines that is piperidine substituted by (4-carboxyphenyl)methyl and {[(1R,2S)-2-phenylcyclopropyl]amino}methyl groups at positions 1 and 4, respectively. It is a potent and irreversible inhibitor of lysine specific demethylase 1 (LSD1, also known as KDM1A). It was under clinical investigation for the treatment of acute myeloid leukaemia and small cell lung carcinoma. | GSK2879552 |
| ibutilide | | Ibutilide |
| ifetroban | | ifetroban |
| iophenoxic acid | | iophenoic acid |
| iprodione | An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide. | iprodione |
| isocarboxazid | | 5-methyl-N'-(phenylmethyl)-3-isoxazolecarbohydrazide |
| Isopropyl phenylacetate | | Isopropyl phenylacetate |
| k 858 | | N-(4-acetyl-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide |
| l 744832 | A secondary carboxamide resulting from the formal condensation of the carboxy group of 2-{[(2S,3S)-2-{[(2R)-2-amino-3-sulfanylpropyl]amino}-3-methylpentyl]oxy}-3-phenylpropanoic acid with the amino group of propan-2-yl (2S)-2-amino-4-(methylsulfonyl)butanoate. It is a farnesyltransferase inhibitor that exhibits anticancer properties. | L-744,832 |
| l796778 | A methyl ester resulting from the formal condensation of the carboxy group of N-{[(2S)-1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl}-D-norleucyl-L-lysine with methanol. It is a partial agonist of somatostatin subtype receptor 3 (Ki = 24 nM) that exhibits anticonvulsant effects. | L-796,778 |
| l803087 | A fluoroindole that is 1H-indole substituted by phenyl, 4-{[(2S)-5-carbamimidamido-1-methoxy-1-oxopentan-2-yl]amino}-4-oxobutyl, fluoro and fluoro groups at positions 2, 3, 5 and 7, respectively. It is a selective nonpeptidic agonist of the somatostatin subtype-4 (SST4) receptor with Ki of 0.7 nM. | L-803087 |
| labetalol | A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5. | 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide |
| lidocaine | The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline. | lidocaine |
| magnesium salicylate | | Magnesium salicylate |
| mandelic acid | A 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. | mandelic acid |
| mebanazine | | mebanazine |
| mepiperphenidol | | mepiperphenidol |
| metahexamide | | metahexamide |
| methadone | A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4. | 6-(dimethylamino)-4,4-diphenylheptan-3-one |
| methaphenilene | | Methaphenilene |
| methyl mandelate | | Mandelic Acid, Methyl Ester |
| methyl phenyl sulfoxide | A sulfoxide resulting from the formal oxidation of the sulfur atom of thioanisole. | (methylsulfinyl)benzene |
| methyl phenylacetate | | Methyl benzeneacetate |
| methylphenylsulfide | An aryl sulfide that is thiophenol in which the hydrogen of the thiol group has been replaced by a methyl group. | thioanisole |
| metolachlor | An organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl) group at the nitrogen atom. | 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide |
| mexacarbate | | Mexacarbate |
| mitiglinide | | mitiglinide |
| monodesmethylcitalopram | | Demethylcitalopram |
| N-(3-cyano-5-methyl-4-phenyl-2-thiophenyl)-3,5-dimethyl-4-isoxazolecarboxamide | | N-(3-cyano-5-methyl-4-phenyl-2-thiophenyl)-3,5-dimethyl-4-isoxazolecarboxamide |
| N-(3-phenylpropyl)methanesulfonamide | | N-(3-phenylpropyl)methanesulfonamide |
| N-(3,4-dihydro-2H-pyrrol-5-yl)-5-phenyl-1,3,4-oxadiazol-2-amine | | N-(3,4-dihydro-2H-pyrrol-5-yl)-5-phenyl-1,3,4-oxadiazol-2-amine |
| n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide | A member of the class of coumarins that is 2H-chromen-2-one substituted by 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl, methyl, and diethylamino groups at positions 3, 4 and 7, respectively. It is a thiol-reactive fluorescent dye. | 7-diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin |
| N-(cyclopropylmethyl)-N'-phenylurea | | N-(cyclopropylmethyl)-N'-phenylurea |
| N-[[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide | | N-[[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide |
| N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide | | N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide |
| N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)aniline | | N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)aniline |
| N-[5-(phenylmethyl)-1,3,4-thiadiazol-2-yl]carbamic acid methyl ester | | N-[5-(phenylmethyl)-1,3,4-thiadiazol-2-yl]carbamic acid methyl ester |
| n-acetylphenelzine | | N2-Acetylphenelzine |
| n-alpha-benzoyl-n5-(2-chloro-1-iminoethyl)-l-ornithine amide | | Cl-Amidine |
| N-benzylquinazolin-4-amine | A member of the class of quinazolines that is quinazoline which is substituted by a benzylnitrilo group at position 4. | N-benzylquinazolin-4-amine |
| N-bis(N-methylanilino)phosphoryl-N-methylaniline | | N-bis(N-methylanilino)phosphoryl-N-methylaniline |
| N-methyl-3-[5-(3-phenylpropyl)-1,3,4-oxadiazol-2-yl]-N-(3-thiophenylmethyl)propanamide | | N-methyl-3-[5-(3-phenylpropyl)-1,3,4-oxadiazol-2-yl]-N-(3-thiophenylmethyl)propanamide |
| N-methyl-N-phenylthiourea | | N-methyl-N-phenylthiourea |
| N'-[5-(phenylmethyl)-4,5-dihydrothiazol-2-yl]hexanehydrazide | | N'-[5-(phenylmethyl)-4,5-dihydrothiazol-2-yl]hexanehydrazide |
| N'-methyl-N,N-diphenylurea | | N'-methyl-N,N-diphenylurea |
| N1-phenethylhydrazine-1-carbothioamide | | N1-phenethylhydrazine-1-carbothioamide |
| N1,N4-bis(1-phenylethyl)cyclohexane-1,4-dicarboxamide | | N1,N4-bis(1-phenylethyl)cyclohexane-1,4-dicarboxamide |
| nafoxidine | | Nafoxidine |
| neticonazole | An enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections. | neticonazole |
| nicardipine | A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively. | 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| niraparib | A member of the class of indazoles that is 2H-indazole substituted by 4-(piperidin-3-yl)phenyl and aminocarbonyl groups at positions 2 and 7, respectively. It is a potent PARP1 inhibitor with IC50 of 3.2 nM. | 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide |
| nitrosobenzene | A nitroso compound that is the nitroso derivative of benzene; a diamagnetic hybrid of singlet O2 and azobenzene. | nitrosobenzene |
| np 031112 | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. | tideglusib |
| npi 2358 | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. | plinabulin |
| phencyclidine | A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects. | phencyclidine |
| phenprobamate | | Phenprobamate |
| phenyl acetate | An acetate ester obtained by the formal condensation of phenol with acetic acid. | phenyl acetate |
| phenyl isocyanate | An isocyanate composed of a benzene ring bearing a single isocyanato substituent. | phenyl isocyanate |
| phenylacetic acid | A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group. | phenylacetic acid |
| phenylacetylene | | Ethynylbenzene |
| phenylethyl alcohol | A primary alcohol that is ethanol substituted by a phenyl group at position 2. | 2-phenylethanol |
| phenylheptatriyne | | 1-Phenylhepta-1,3,5-triyne |
| phenylisopropyladenosine | A hydrocarbyladenosine in which adenosine is substituted at N-6 by a (2R)-1-phenylpropan-2-yl group. It is a potent adenosine A1 receptor agonist that exhibits neuroprotective and antinociceptive properties. | (-)-N(6)-(2-phenylisopropyl)adenosine; (-)-n6-(2-phenylisopropyl)adenosine |
| phenylmercuric acetate | | phenylmercury acetate |
| phenylphosphonic acid | | Phenylphosphonic acid |
| phenylpropiolic acid | An acetylenic compound that is propynoic acid in which the acetylenic hydrogen is replaced by a phenyl group. | phenylpropiolic acid |
| phevalin | A member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 muM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression. | phevalin |
| pifithrin mu | | 2-phenylethynesulfonamide |
| piscidic acid | | piscidic acid |
| pivalylbenzhydrazine | | pivhydrazine |
| plerixafor | An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. | plerixafor |
| propham | A carbamate ester that is the isopropyl ester of phenylcarbamic acid. It is a selective herbicide used for the control of annual grasses and some broad-leaf weeds and is also a growth regulator for control of sprouting in stored potatoes. | propham |
| prosulfocarb | A monothiocarbamic ester that is carbamothioic S-acid substituted by two propyl groups at the nitrogen atom and a benzyl group at the the sulfur atom. | prosulfocarb |
| pyrazon | A pyridazinone that is pyridazin-3(2H)-one substituted by an amino group at position 5, a chloro group at position 4 and a phenyl group at position 2. | chloridazon |
| ripazepam | | Ripazepam |
| ro 25-6981 | A member of the class of piperidines that is 4-benzylpiperidine substituted by a 3-hydroxy-3-(4-hydroxyphenyl)-2-methylpropyl group at position 1 (the 1R,2S-stereoisomer). It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor. | Ro 25-6981 |
| ro 4-6790 | | 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide |
| sdds | | Sulfamoyldapsone |
| silomat | | Clobutinol hydrochloride |
| sm 164 | A potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models. | SM-164 |
| styrene glycol | | 1-Phenyl-1,2-ethanediol |
| sulfabenzamide | A sulfonamide containing a benzamido substituent on nitrogen. An antibacterial/antimicrobial, it is often used in conjunction with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation. | sulfabenzamide |
| sulfacytine | | sulfacytine |
| sulfaethidole | | 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide |
| sulfamonomethoxine | | Sulfamonomethoxine |
| sulfanilylurea | | sulfacarbamide |
| sulfaquinoxaline | | 4-amino-N-(2-quinoxalinyl)benzenesulfonamide |
| sulfatolamide | | Sulfatolamide |
| SYC-435 | A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and benzyl groups, respectively. It is a potent inhibitor of mutant isocitrate dehydrogenase 1 (Ki values of 190 nM against R132H mutant and 120 nM against R132C mutant). | SYC-435 |
| teclozan | | teclozan |
| thiobenzamide | | Thiobenzamide |
| tolazoline hydrochloride | | Tolazoline hydrochloride |
| trelagliptin | | trelagliptin |
| tribuzone | | tribuzone |
| triphenylphosphine | A member of the class of tertiary phosphines that is phosphane in which the three hydrogens are replaced by phenyl groups. | triphenylphosphine |
| tyropanoate | | tyropanoate |
| u 40481 | A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz. | N'-(2,4-dimethylphenyl)-N-methylformamidine |
| varespladib | A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects. | varespladib |
| varespladib methyl | A methyl ester resulting from the formal condensation of the carboxy group of varespladib with methanol. It is a potential therapy for the treatment of snakebite envenomings in which toxicity depends on the action of PLA2s. | varespladib methyl |
| warfarin | A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one |
| ws-5995 c | | 2-(1,5-Dihydroxy-3,4-dioxonaphthalen-2-yl)-3-methoxy-5-methylbenzoic acid |
| ym 216391 | An azamacrocycle with formula C34H32N8O7S isolated from the cultured mycelium of Streptomyces nobilis. It exhibits potent cytotoxic activity against human cancer cell lines. | YM-216391 |