Page last updated: 2024-08-05 10:33:10
oxo dicarboxylic acid
Any dicarboxylic acid carrying one or more oxo groups.
ChEBI ID: 36145
Members (10)
| Member | Definition | Role |
|---|---|---|
| 3-oxoadipic acid | An oxo dicarboxylic acid consisting of adipic acid having a single oxo group at the 3-position. | 3-oxoadipic acid |
| alpha-ketoadipic acid | An oxo dicarboxylic acid that is adipic acid substituted by an oxo group at position 2. | 2-oxoadipic acid |
| alpha-ketoglutaric acid | An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. | 2-oxoglutaric acid |
| fumarylacetoacetate | 4-fumarylacetoacetic acid | |
| glycyrrhetyl 3-monoglucuronide | A triterpenoid saponin that is the 3-O-beta-glucuronide of glycyrrhetic acid. It is a metabolite of glycyrrhizin contained in licorice and potentially a causative agent in the pathogenesis of pseudoaldosteronism. | glycyrrhetic acid 3-O-glucuronide |
| mesoxalic acid | oxomalonic acid | |
| oxaloacetic acid | An oxodicarboxylic acid that is succinic acid bearing a single oxo group. | oxaloacetic acid |
| prephenic acid | An oxo dicarboxylic acid that consists of 4-hydroxycyclohexa-2,5-diene-1-carboxylic acid substituted by a 2-carboxy-2-oxoethyl group at position 1. | prephenic acid |
| sennoside A | A member of the class of sennosides that is rel-(9R,9'R)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. The exact stereochemisty at positions 9 and 9' is not known - it may be R,R (as shown) or S,S. | sennoside A |
| sennoside B | A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. | sennoside B |
Research
Studies (700)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 141 (20.14) | 18.7374 |
| 1990's | 72 (10.29) | 18.2507 |
| 2000's | 196 (28.00) | 29.6817 |
| 2010's | 239 (34.14) | 24.3611 |
| 2020's | 52 (7.43) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (0.28%) | 5.53% |
| Reviews | 27 (3.72%) | 6.00% |
| Case Studies | 11 (1.52%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 686 (94.49%) | 84.16% |