Page last updated: 2024-08-05 12:53:11

spiro-epoxide

An oxaspiro compound in which a carbon atom of an epoxide ring is the only common member of two rings.

ChEBI ID: 133131

Members (8)

MemberDefinitionRole
arenaemycin eA sesquiterpene lactone that is isolated from several Streptomyces species and exhibits antibiotic activity.pentalenolactone
fr 901464A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663.FR901464
fumagillinA meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.fumagillin
fumagillolA sesquiterpenoid with antimicrobial properties.fumagillol
o-(chloroacetylcarbamoyl)fumagillolA carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative.O-(chloroacetylcarbamoyl)fumagillol
pentalenolactone fA tetracyclic sesquiterpene lactone obtained by formal epoxidation of the 4-methylene group of pentalenolactone E.pentalenolactone F
petasiteninePetasitenine
streptolydiginA monocarboxylic acid amide that is a broad-spectrum antibiotic produced by Streptomyces lydicus.streptolydigin

Research

Studies (814)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990101 (12.41)18.7374
1990's235 (28.87)18.2507
2000's328 (40.29)29.6817
2010's133 (16.34)24.3611
2020's17 (2.09)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials15 (1.62%)5.53%
Reviews79 (8.55%)6.00%
Case Studies23 (2.49%)4.05%
Observational0 (0.00%)0.25%
Other807 (87.34%)84.16%