Page last updated: 2024-08-05 12:53:11
spiro-epoxide
An oxaspiro compound in which a carbon atom of an epoxide ring is the only common member of two rings.
ChEBI ID: 133131
Members (8)
Member | Definition | Role |
---|---|---|
arenaemycin e | A sesquiterpene lactone that is isolated from several Streptomyces species and exhibits antibiotic activity. | pentalenolactone |
fr 901464 | A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663. | FR901464 |
fumagillin | A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. | fumagillin |
fumagillol | A sesquiterpenoid with antimicrobial properties. | fumagillol |
o-(chloroacetylcarbamoyl)fumagillol | A carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative. | O-(chloroacetylcarbamoyl)fumagillol |
pentalenolactone f | A tetracyclic sesquiterpene lactone obtained by formal epoxidation of the 4-methylene group of pentalenolactone E. | pentalenolactone F |
petasitenine | Petasitenine | |
streptolydigin | A monocarboxylic acid amide that is a broad-spectrum antibiotic produced by Streptomyces lydicus. | streptolydigin |
Research
Studies (814)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 101 (12.41) | 18.7374 |
1990's | 235 (28.87) | 18.2507 |
2000's | 328 (40.29) | 29.6817 |
2010's | 133 (16.34) | 24.3611 |
2020's | 17 (2.09) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 15 (1.62%) | 5.53% |
Reviews | 79 (8.55%) | 6.00% |
Case Studies | 23 (2.49%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 807 (87.34%) | 84.16% |