Any compound containing an indole skeleton.
| Member | Definition | Role |
|---|
| (11S,14S)-Cyclo-(L-Trp-L-Phe) | | (11S,14S)-Cyclo-(L-Trp-L-Phe) |
| (2R,4R)-4-(1-acetyl-3-indolyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-(phenylmethyl)-3,4-dihydro-2H-pyran-6-carboxamide | | (2R,4R)-4-(1-acetyl-3-indolyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-(phenylmethyl)-3,4-dihydro-2H-pyran-6-carboxamide |
| (3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)-4-pyrimidinyl]-3-methylmorpholine | | (3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)-4-pyrimidinyl]-3-methylmorpholine |
| (5-ethyl-8-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazine | | (5-ethyl-8-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazine |
| (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | A dihydroxy monocarboxylic acid that is N-isopropylindole which is substituted at position 3 by a p-fluorophenyl group and at position 2 by a 6-carboxy-3,5-dihydroxyhex-1-en-1-yl group. It has four possible diastereoisomers. | (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid |
| [1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione | | [1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione |
| [1-[2-(2-methylphenoxy)ethyl]-3-indolyl]-(4-methyl-1-piperazinyl)methanethione | | [1-[2-(2-methylphenoxy)ethyl]-3-indolyl]-(4-methyl-1-piperazinyl)methanethione |
| 1-(1H-indol-3-yl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanone | | 1-(1H-indol-3-yl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanone |
| 1-(2-methyl-1H-indol-3-yl)-2-(2-thiazolylamino)ethanone | | 1-(2-methyl-1H-indol-3-yl)-2-(2-thiazolylamino)ethanone |
| 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-2-tetrazolyl)ethanone | | 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-2-tetrazolyl)ethanone |
| 1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone | | 1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone |
| 1-(2,6-dimethyl-1H-indol-3-yl)-2-(1-pyrrolidinyl)ethanone | | 1-(2,6-dimethyl-1H-indol-3-yl)-2-(1-pyrrolidinyl)ethanone |
| 1-(3-phenoxypropyl)-3-indolecarbonitrile | | 1-(3-phenoxypropyl)-3-indolecarbonitrile |
| 1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol | | 1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol |
| 1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thiourea | | 1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thiourea |
| 1-[(2-oxo-1,3-dihydroindol-5-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester | | 1-[(2-oxo-1,3-dihydroindol-5-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester |
| 1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione | | 1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione |
| 1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-4-piperidinecarboxylic acid ethyl ester | | 1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-4-piperidinecarboxylic acid ethyl ester |
| 1-[2-(1H-indol-3-yl)ethyl]-5,6,7,8-tetrahydroquinolin-4-one | | 1-[2-(1H-indol-3-yl)ethyl]-5,6,7,8-tetrahydroquinolin-4-one |
| 1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thiourea | | 1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thiourea |
| 1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-(thiophen-2-ylmethyl)thiourea | | 1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-(thiophen-2-ylmethyl)thiourea |
| 1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thiourea | | 1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thiourea |
| 1-[2-(hydroxymethyl)-1-benzimidazolyl]-3-(1-indolyl)-2-propanol | | 1-[2-(hydroxymethyl)-1-benzimidazolyl]-3-(1-indolyl)-2-propanol |
| 1-[3-[(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-6-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]-3,4-dihydro-2H-pyran-4-yl]-1-indolyl]ethanone | | 1-[3-[(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-6-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]-3,4-dihydro-2H-pyran-4-yl]-1-indolyl]ethanone |
| 1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone | | 1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone |
| 1-[cyclopropyl(oxo)methyl]-N-(2-hydroxyethyl)-N-(phenylmethyl)-2,3-dihydroindole-5-sulfonamide | | 1-[cyclopropyl(oxo)methyl]-N-(2-hydroxyethyl)-N-(phenylmethyl)-2,3-dihydroindole-5-sulfonamide |
| 1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide | | 1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide |
| 1-cyclohexyl-3-[(1,2-dimethyl-5-indolyl)methyl]urea | | 1-cyclohexyl-3-[(1,2-dimethyl-5-indolyl)methyl]urea |
| 1-methyl-2-[(4-methyl-1-piperidinyl)methyl]-3-indolecarbonitrile | | 1-methyl-2-[(4-methyl-1-piperidinyl)methyl]-3-indolecarbonitrile |
| 1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrile | | 1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrile |
| 1-oxo-3-(1-piperidinyl)-5,6,7,8-tetrahydropyrrolo[1,2-a]indole-2-carbonitrile | | 1-oxo-3-(1-piperidinyl)-5,6,7,8-tetrahydropyrrolo[1,2-a]indole-2-carbonitrile |
| 10H-[1]benzothiolo[3,2-b]indole | | 10H-[1]benzothiolo[3,2-b]indole |
| 1H-indol-3-yl(pyridin-2-yl)methanol | | 1H-indol-3-yl(pyridin-2-yl)methanol |
| 2-(1H-indol-3-yl)-2-oxo-N-(2-thiazolyl)acetamide | | 2-(1H-indol-3-yl)-2-oxo-N-(2-thiazolyl)acetamide |
| 2-(1H-indol-3-ylthio)acetic acid | | 2-(1H-indol-3-ylthio)acetic acid |
| 2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanone | | 2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanone |
| 2-(2-methyl-1H-indol-3-yl)ethanol | | 2-(2-methyl-1H-indol-3-yl)ethanol |
| 2-(2,3-dihydro-1H-inden-5-yloxy)-1-(2,3-dihydroindol-1-yl)ethanone | | 2-(2,3-dihydro-1H-inden-5-yloxy)-1-(2,3-dihydroindol-1-yl)ethanone |
| 2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamine | | 2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamine |
| 2-(3-acetyl-1-indolyl)-N-(2,4-dimethylphenyl)acetamide | | 2-(3-acetyl-1-indolyl)-N-(2,4-dimethylphenyl)acetamide |
| 2-(6-cyano-1-indolyl)-N-cyclohexylacetamide | | 2-(6-cyano-1-indolyl)-N-cyclohexylacetamide |
| 2-[(1-methyl-3-indolyl)thio]-N-(2-thiazolyl)acetamide | | 2-[(1-methyl-3-indolyl)thio]-N-(2-thiazolyl)acetamide |
| 2-[(1R,3S)-3-(7-bromo-2-methyl-1H-indol-3-yl)-2,2-dimethylcyclopropyl]acetonitrile | | 2-[(1R,3S)-3-(7-bromo-2-methyl-1H-indol-3-yl)-2,2-dimethylcyclopropyl]acetonitrile |
| 2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile | | 2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile |
| 2-[[1-(phenylmethyl)-3-indolyl]thio]-N-(2-thiazolyl)acetamide | | 2-[[1-(phenylmethyl)-3-indolyl]thio]-N-(2-thiazolyl)acetamide |
| 2-[[1-[(3-bromophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | | 2-[[1-[(3-bromophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide |
| 2-[[1-[(3-chlorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | | 2-[[1-[(3-chlorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide |
| 2-[[1-[(3-fluorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide | | 2-[[1-[(3-fluorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide |
| 2-[[4-amino-5-(3,4-dimethoxyphenyl)-1,2,4-triazol-3-yl]thio]-1-(1H-indol-3-yl)-2-phenylethanone | | 2-[[4-amino-5-(3,4-dimethoxyphenyl)-1,2,4-triazol-3-yl]thio]-1-(1H-indol-3-yl)-2-phenylethanone |
| 2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioic acid diethyl ester | | 2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioic acid diethyl ester |
| 2-[1-[2-(diethylamino)-2-oxoethyl]-3-indolyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetamide | | 2-[1-[2-(diethylamino)-2-oxoethyl]-3-indolyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetamide |
| 2-[3-[[2-oxo-2-(1-pyrrolidinyl)ethyl]thio]-1-indolyl]-N,N-di(propan-2-yl)acetamide | | 2-[3-[[2-oxo-2-(1-pyrrolidinyl)ethyl]thio]-1-indolyl]-N,N-di(propan-2-yl)acetamide |
| 2-chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester | | 2-chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester |
| 2-methyl-3-(phenylmethylthio)-1H-indole | | 2-methyl-3-(phenylmethylthio)-1H-indole |
| 2-methyl-3-[(2-methyl-1H-indol-3-yl)-(2-pyridinyl)methyl]-1H-indole | | 2-methyl-3-[(2-methyl-1H-indol-3-yl)-(2-pyridinyl)methyl]-1H-indole |
| 2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide | | 2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide |
| 2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester | | 2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester |
| 2,6-difluoro-N-[2-[3-[(2-fluorophenyl)methylthio]-1-indolyl]ethyl]benzamide | | 2,6-difluoro-N-[2-[3-[(2-fluorophenyl)methylthio]-1-indolyl]ethyl]benzamide |
| 3-(4-pyridyl)-1h-indole | | 3-pyridin-4-yl-1H-indole |
| 3-(hydroxyacetyl)indole | | Hydroxymethyl indol-3-yl ketone |
| 3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one | | 3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one |
| 3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one | | 3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one |
| 3-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-N-[(5-methyl-2-furanyl)methyl]propanamide | | 3-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-N-[(5-methyl-2-furanyl)methyl]propanamide |
| 3-[2-(2,4-dimethyl-3-furanyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indolone | | 3-[2-(2,4-dimethyl-3-furanyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indolone |
| 3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one | | 3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one |
| 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester | | 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester |
| 3-methyleneindolenine | An indole that consists of 3H-indole bearing a methylene substituent at position 3. | 3-methyleneindolenine |
| 3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one | | 3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one |
| 3,3'-diindolylmethane | | 3,3'-diindolylmethane |
| 4-(1-methyl-3-indolyl)-N-propan-2-ylbutanamide | | 4-(1-methyl-3-indolyl)-N-propan-2-ylbutanamide |
| 4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-N-(2-oxolanylmethyl)-2-thiazolamine | | 4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-N-(2-oxolanylmethyl)-2-thiazolamine |
| 4-(1H-indol-3-yl)butanoic acid [2-(3-methoxyanilino)-2-oxoethyl] ester | | 4-(1H-indol-3-yl)butanoic acid [2-(3-methoxyanilino)-2-oxoethyl] ester |
| 4-(1H-indol-3-yl)butanoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester | | 4-(1H-indol-3-yl)butanoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester |
| 4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamide | | 4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamide |
| 4-(5-methoxy-1,2-dimethyl-3-indolyl)-2-thiazolamine | | 4-(5-methoxy-1,2-dimethyl-3-indolyl)-2-thiazolamine |
| 4-[(1,2-dimethyl-5-indolyl)methylamino]-4-oxobutanoic acid | | 4-[(1,2-dimethyl-5-indolyl)methylamino]-4-oxobutanoic acid |
| 4-[[1-[(3,4-dichlorophenyl)methyl]-3-indolyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one | | 4-[[1-[(3,4-dichlorophenyl)methyl]-3-indolyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one |
| 4-[2-[[1-[(2-methylphenyl)methyl]-3-indolyl]sulfonyl]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester | | 4-[2-[[1-[(2-methylphenyl)methyl]-3-indolyl]sulfonyl]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester |
| 4-amino-2-[[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thio]-5-pyrimidinecarboxylic acid ethyl ester | | 4-amino-2-[[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thio]-5-pyrimidinecarboxylic acid ethyl ester |
| 4-chloro-N-[2-(1H-indol-3-yl)-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl]benzamide | | 4-chloro-N-[2-(1H-indol-3-yl)-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl]benzamide |
| 5-[[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]methyl]-2-furancarboxylic acid methyl ester | | 5-[[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]methyl]-2-furancarboxylic acid methyl ester |
| 5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide | | 5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide |
| 5-bromo-4-chloro-3-indoxyl phosphate | An aryl phosphate that is indoxyl phopshate in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively. It is used to test for the presence of an enzyme, alkaline phosphatase, which cleaves the phosphate group to give 5-bromo-4-chloroindoxyl, which immediately dimerises to give an intensely blue product. | 5-bromo-4-chloro-3-indolyl phosphate |
| 5-bromo-N-[(1,2-dimethyl-5-indolyl)methyl]-2-furancarboxamide | | 5-bromo-N-[(1,2-dimethyl-5-indolyl)methyl]-2-furancarboxamide |
| 5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamide | | 5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamide |
| 5-bromoisatin | | 5-Bromoisatin |
| 5-Chloro-1H-indole-2,3-dione | | 5-Chloro-1H-indole-2,3-dione |
| 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole | | 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole |
| 5-Fluoroisatin | | 5-Fluoroisatin |
| 5-iodoisatin | | 5-Iodoisatin |
| 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole | | 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole |
| 5-methoxyindole | | 5-methoxyindole |
| 5-methoxyindole-3-carbaldehyde | | 5-methoxyindole-3-carbaldehyde |
| 5-Methoxyisatin | | 5-Methoxyisatin |
| 5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione | | 5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione |
| 5-Nitroisatin | | 5-Nitroisatin |
| 6-(2-chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-one | | 6-(2-chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-one |
| 6-chloroindole | | 6-Chloroindole |
| 8-(1H-indol-3-ylmethylidene)-6,10-dioxaspiro[4.5]decane-7,9-dione | | 8-(1H-indol-3-ylmethylidene)-6,10-dioxaspiro[4.5]decane-7,9-dione |
| a 443654 | | (2S)-1-(1H-indol-3-yl)-3-[[5-(3-methyl-2H-indazol-5-yl)-3-pyridinyl]oxy]-2-propanamine |
| acarbose | A chondramide that is chondramide A in which the hydrogen at position 2 of the indole moiety has been replaced by a chlorine. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide B |
| acetic acid [2-(1-acetyl-6-indolyl)-2-oxoethyl] ester | | acetic acid [2-(1-acetyl-6-indolyl)-2-oxoethyl] ester |
| adrenochrome | | Adrenochrome |
| AG-370 | | AG-370 |
| almotriptan | An indole compound having a 2-(dimethylamino)ethyl group at the 3-position and a (pyrrolidin-1-ylsulfonyl)methyl group at the 5-position. | almotriptan |
| am 694 | A member of the class of indoles that is 1H-indole which is substituted at position 1 by a 5-fluoropentyl group and a position 3 by an o-fluorobenzoyl group. It is a selective agonist for the CB1 cannabinoid receptor; Ki values for the CB1 and CB2 receptors are 0.08 and 1.44 nM, respectively. | 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole |
| amaranthin betacyanin | A disaccharide derivative that is betanidin in which a beta-D-glucuronosyl-(1->2)-beta-D-glucosyl moiety is attached at position 5. | amaranthin |
| apaziquone | | Apaziquone |
| arq 197 | | LSM-1131 |
| asperlicin c | A member of the class of asperlicins in which the core 6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione skeleton is substituted at the 7 pro-S position by an indol-3-ylmethyl group. It is a cholecystokinin antagonist. | asperlicin C |
| AZD3463 | A member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. | AZD3463 |
| beta-indol-3-yl-glucoside | | beta-indol-3-yl-glucoside |
| bisindolylmaleimide iii | | bisindolylmaleimide III |
| bisindolylmaleimide iv | | 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione |
| bisindolylmaleimide v | | Ro 31-6045 |
| brassilexin | | Brassilexin |
| brevianamide f | A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tryptophan and L-proline). | brevianamide F |
| chaetoglobosin A | A cytochalasan alkaloid isolated from Chaetomium globosum and Calonectria morganii. | chaetoglobosin A |
| chetomin | An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity. | chetomin |
| chondramide a | A chondramide that is chondramide C in which the pro-S hydrogen at position 2 of the beta-tyrosine residue is replaced by a methoxy group. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide A |
| chondramide c | A chondramide formally obtained from N-[(2S,4E,6R,7R)-7-hydroxy-2,4,6-trimethyloct-4-enoyl]-L-alanyl-Nalpha-methyl-D-tryptophanyl-beta-R-beta-tyrosine by intramolecular condensation of the alcoholic hydroxy group with the carboxy group of the beta-tyrosine residue. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide C |
| chondramide d | A chondramide that is chondramide C in which the hydrogen at position 2 of the indole moiety is replaced by a chlorine. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide D |
| chromopyrrolic acid | A pyrroledicarboxylic acid that is pyrrole-2,5-dicarboxylic acid in which the hydrogens at positions 3 and 4 have been replaced by indol-3-yl groups. | chromopyrrolic acid |
| cink4 | | 4-[[6-(ethylamino)-2-[[1-(phenylmethyl)-5-indolyl]amino]-4-pyrimidinyl]amino]-1-cyclohexanol |
| ck-0944666 | A member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation. | CK-666 |
| complestatin | A heterodetic cyclic peptide consisting of N-acylated trytophan, 3,5-dichloro-4-hydroxyphenylglycine, 4-hydroxyphenylglycine, 3,5-dichloro-4-hydroxyphenylglycyl, tyrosine and 4-hydroxyphenylglycine residues joined in sequence and in which the side-chain of the central 4-hydroxyphenylglycine residue is attached to the side-chain of the tryptophan via a C3-C6 bond and to the side-chain of the tyrosine via an ether bond from C5. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. | chloropeptin II; isocomplestatin |
| cyanopindolol | | 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile |
| cyclo(glycyltryptophyl) | | Cyclo(glycyltryptophyl) |
| cyclobutyl-[5-[(2-ethyl-1-piperidinyl)sulfonyl]-2,3-dihydroindol-1-yl]methanone | | cyclobutyl-[5-[(2-ethyl-1-piperidinyl)sulfonyl]-2,3-dihydroindol-1-yl]methanone |
| dapi | | DAPI |
| dendrobine | | Dendrobine |
| Dihydro-beta-erythroidine hydrobromide | | Dihydro-beta-erythroidine hydrobromide |
| echinuline | An indole alkaloid with formula C29H39N3O2. It is a fungal metabolite found in several Aspergillus species. | echinulin |
| eletriptan | An N-alkylpyrrolidine, that is N-methylpyrrolidine in which the pro-R hydrogen at position 2 is replaced by a {5-[2-(phenylsulfonyl)ethyl]-1H-indol-3-yl}methyl group. | eletriptan |
| enzastaurin | | 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dione |
| etryptamine | | etryptamine |
| fumiquinazoline f | A fumiquinazoline that consists of pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione bearing a methyl substituent at position 1 and an indol-3-yl group at position 4. | fumiquinazoline F |
| geneserine | | Eseridine |
| gö6983 | | 3-[1-[3-(dimethylamino)propyl]-5-methoxy-3-indolyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione |
| gsk2656157 | A pyrrolopyrimidine that is 7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine which has been substituted at position 5 by a 4-fluoro-2,3-dihydro-1H-indol-5-yl group, the nitrogen of which has been acylated by a (6-methylpyridin-2-yl)acetyl group. An orally bioavailable PERK inhibitor. | GSK2656157 |
| hydroxytryptophol | | 5-Hydroxytryptophol |
| ic 261 | | 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one |
| ici 204,219 | | zafirlukast |
| indalpine | | indalpine |
| indapamide | A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine. | indapamide |
| indican | An aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group. | indoxyl sulfate |
| indo-1 | | Indo-1 dye |
| indolactam v | | (-)-indolactam V |
| indole-3-acetonitrile | A nitrile that is acetonitrile where one of the methyl hydrogens is substituted by a 1H-indol-3-yl group. | indole-3-acetonitrile |
| indole-3-carbaldehyde | A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. | indole-3-carbaldehyde |
| indoleacetamide | A member of the class of indoles that is acetamide substituted by a 1H-indol-3-yl group at position 2. It is an intermediate in the production of plant hormone indole acetic acid (IAA). | indole-3-acetamide |
| indolepropanol phosphate | An monoalkyl phosphate compound having an O-3-(indol-3-yl)propyl substituent. | 3-(indol-3-yl)propyl phosphate |
| indoline | | indoline |
| indolmycin | A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted at the 2 and 5-pro-S positions by methylamino and [(1R)-1-(1H-indol-3-yl)ethyl] groups, respectively. | indolmycin |
| indoxyl acetate | | Indoxyl acetate |
| iprindole | | iprindole |
| koumine | | 15-Ethenyl-13-methyl-19-oxa-3,13-diazahexacyclo[14.3.1.02,10.04,9.010,15.012,17]icosa-2,4,6,8-tetraene |
| l 663536 | A member of the class of indoles that is 1H-indole substituted by a isopropyl group at position 5, a tert-butylsulfanediyl group at position 3, a 4-chlorobenzyl group at position 1 and a 2-carboxy-2-methylpropyl group at position 2. It acts as an inhibitor of arachidonate 5-lipoxygenase. | 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid |
| l 779976 | A member of the class of indoles that is (betaS)-beta-methyl-D-tryptophan in which the primary amino group undergoes formal condensation with the carboxy group of 4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylic acid and the carboxy group undegoes formal condensation with the amino group of (1R,3S)-cyclohexane-1,3-diyldimethanamine. It is a selective nonpeptidic agonist of the somatostatin subtype-2 (SST2) receptor with Ki of 0.05 nM. | L-779976 |
| le 300 | | LSM-2007 |
| leukodopachrome | Indoline substituted with hydroxy groups at C-5 and -6 and a carboxy group at C-2, and with S stereochemistry at C-2. | leucodopachrome |
| linopirdine | | Linopirdine |
| LSM-18452 | | LSM-18452 |
| LSM-2818 | | LSM-2818 |
| LSM-33266 | | LSM-33266 |
| LSM-3511 | | LSM-3511 |
| LSM-3706 | | LSM-3706 |
| lugdunin | A thiazolidine-containing homodetic cyclic peptide that is isolated from human nasal bacteria. Exhibits bactericidal activity against many major pathogens including methicillin-resistant Staphylococcus aureus (MRSA). | lugdunin |
| luzindole | A member of the class of indoles that is tryptamine in which one of the amino hydrogens is replaced by an acetyl group while the hydrogen at position 2 is replaced by a benzyl group. | luzindole; N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]acetamide |
| lyngbyatoxin a | | lyngbyatoxin A |
| mebhydroline | | mebhydrolin |
| mepindolol | | mepindolol |
| methoxytryptophol | | 5-Methoxytryptophol |
| methyl indole-3-carboxylate | The methyl ester of indole-3-carboxylic acid. | methyl indole-3-carboxylate |
| molindone | | Molindone |
| molindone hydrochloride | | Molindone hydrochloride |
| N-(1-acetyl-2-chloro-3-indolyl)-2-chloroacetamide | | N-(1-acetyl-2-chloro-3-indolyl)-2-chloroacetamide |
| N-(1-acetyl-2,3-dihydroindol-5-yl)-4-methylbenzamide | | N-(1-acetyl-2,3-dihydroindol-5-yl)-4-methylbenzamide |
| n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea | A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. | 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
| N-(1H-indol-5-yl)-2-thiophenecarboxamide | | N-(1H-indol-5-yl)-2-thiophenecarboxamide |
| N-(2-fluorophenyl)-2-[3-(1-oxopropyl)-1-indolyl]acetamide | | N-(2-fluorophenyl)-2-[3-(1-oxopropyl)-1-indolyl]acetamide |
| N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | | N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide |
| N-(2-furanylmethyl)-2-[3-(1-oxo-2-phenoxyethyl)-1-indolyl]acetamide | | N-(2-furanylmethyl)-2-[3-(1-oxo-2-phenoxyethyl)-1-indolyl]acetamide |
| N-(3-methoxyphenyl)-2-(1-methyl-3-indolyl)acetamide | | N-(3-methoxyphenyl)-2-(1-methyl-3-indolyl)acetamide |
| N-(4-propan-2-ylphenyl)-1-[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonyl]-4-piperidinecarboxamide | | N-(4-propan-2-ylphenyl)-1-[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonyl]-4-piperidinecarboxamide |
| N-[(1,2-dimethyl-5-indolyl)methyl]-2-(4-nitrophenyl)acetamide | | N-[(1,2-dimethyl-5-indolyl)methyl]-2-(4-nitrophenyl)acetamide |
| N-[(1,2-dimethyl-5-indolyl)methyl]-2-methyl-3-nitrobenzamide | | N-[(1,2-dimethyl-5-indolyl)methyl]-2-methyl-3-nitrobenzamide |
| N-[2-(1-cyclohexenyl)ethyl]-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindole-5-sulfonamide | | N-[2-(1-cyclohexenyl)ethyl]-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindole-5-sulfonamide |
| N-[2-(1H-indol-3-yl)ethyl]-4-(phenylmethyl)-5-thieno[3,2-b]pyrrolecarboxamide | | N-[2-(1H-indol-3-yl)ethyl]-4-(phenylmethyl)-5-thieno[3,2-b]pyrrolecarboxamide |
| N-[2-(2-chlorophenoxy)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide | | N-[2-(2-chlorophenoxy)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide |
| N-[2-(2-methyl-1-indolyl)ethyl]benzamide | | N-[2-(2-methyl-1-indolyl)ethyl]benzamide |
| N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide | | N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide |
| N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamide | | N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamide |
| N-[4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide | | N-[4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide |
| N-[4-(2-methyl-1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]-2-thiophen-2-ylacetamide | | N-[4-(2-methyl-1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]-2-thiophen-2-ylacetamide |
| N-[4-(dimethylamino)phenyl]-2-(1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)acetamide | | N-[4-(dimethylamino)phenyl]-2-(1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)acetamide |
| N-[4-[1-(1-oxopropyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-furancarboxamide | | N-[4-[1-(1-oxopropyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-furancarboxamide |
| N-[5-(2,3-dihydroindol-1-ylsulfonyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide | | N-[5-(2,3-dihydroindol-1-ylsulfonyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide |
| N-[amino-[2-(1H-indol-3-yl)ethylimino]methyl]-4-chlorobenzamide | | N-[amino-[2-(1H-indol-3-yl)ethylimino]methyl]-4-chlorobenzamide |
| n-acetyltryptamine | A tryptamine compound having an acetyl substituent attached to the side-chain amino function. | N-acetyltryptamine |
| n-pentanoyl-2-benzyltryptamine | | N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]pentanamide |
| N,N-diethylcarbamodithioic acid [2-(2-methyl-1H-indol-3-yl)-2-oxoethyl] ester | | N,N-diethylcarbamodithioic acid [2-(2-methyl-1H-indol-3-yl)-2-oxoethyl] ester |
| N'-(1h-indol-3-ylmethylene)benzohydrazide | | N'-(1h-indol-3-ylmethylene)benzohydrazide |
| Nb-Palmitoyltryptamine | | Nb-Palmitoyltryptamine |
| nematophin | | Pentanamide, N-[2-(1H-indol-3-yl)ethyl]-3-methyl-2-oxo- |
| neuroprotectin a | A heterodetic cyclic peptide that is chloropeptin II in which the indole moiety is oxidised to the corresponding 2-oxindole. It is a HIV-1 integrase inhibitor isolated from Streptomyces. | complestatin A |
| noradrenochrome | | Noradrenochrome |
| oncrasin-1 | A member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations. | oncrasin-1 |
| osimertinib | A member of the class of aminopyrimidines that is 4-(1-methylindol-3-yl)pyrimidin-2-amine in which one of the amino hydrogens is replaced by a 2-methoxy-4-[2-(dimethylamino)ethyl](methyl)amino-5-acrylamidophenyl group. Used (as the mesylate salt) for treatment of EGFR T790M mutation positive non-small cell lung cancer. | osimertinib |
| oxyphenisatin | | oxyphenisatine |
| pendolmycin | | Pendolmycin |
| pf-562,271 | | N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]methanesulfonamide |
| physovenine | | Physovenine |
| pindolol | A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol. | pindolol |
| quisinostat | | N-hydroxy-2-[4-[[(1-methyl-3-indolyl)methylamino]methyl]-1-piperidinyl]-5-pyrimidinecarboxamide |
| ramosetron | | ramosetron |
| ramosetron hydrochloride | | Ramosetron hydrochloride |
| ro 31-8220 | | Ro 31-8220 |
| ro 60-0175 | A member of the class of indoles that is 6-chloro-5-fluoroindole in which the hydrogen attached to the nitrogen has been replaced by a 2-aminopropyl group. | 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine |
| ropinirole hydrochloride | | Ropinirole hydrochloride |
| roxindole | | roxindole |
| rs 17053 | | 1-(5-chloro-1H-indol-3-yl)-N-[2-[2-(cyclopropylmethoxy)phenoxy]ethyl]-2-methyl-2-propanamine |
| sandoz-21-009 | | 4-(2-Hydroxy-3-tert-butylaminopropoxy)-2-methylindole |
| sb 200646 | | SB 200646 |
| sb 216763 | | 3-(2,4-dichlorophenyl)-4-(1-methyl-3-indolyl)pyrrole-2,5-dione |
| sotrastaurin | A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients. | sotrastaurin |
| tegaserod | | tegaserod |
| THZ531 | A member of the class of indoles that is 5-chloro-4-(1H-indol-3-yl)-N-[(3R)-piperidin-3-yl]pyrimidin-2-amine in which the piperidine NH group is substituted by a 4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzoyl group. It is a first-in-class CDK12 and CDK13 covalent kinase inhibitor with IC50 of 158 nM and 69 nM, respectively. | THZ531 |
| tilivalline | A pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine substituted by an oxo group at position 5, by a hydroxy group at position 9, and by a 1H-indol-3-yl group at position 11S. It is a natural product discovered in Klebsiella oxytoca which is the causative toxin in antibiotic associated hemorrhagic colitis. It exhibits a microtubule-stabilizing activity that leads to mitotic arrest in the host cells. | tilivalline |
| tinazoline | | tinazoline |
| tmc-95a | A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. It includes a R-hydroxy group at position 11 and a (3-methyl-2-oxopentanoyl)amino group at position at position 18 with a S-methyl group. It acts as a proteasome inhibitor and is obtained from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. | TMC-95A |
| tmc-95b | A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. A stereoisomer of TMC-95A, it has a [(3R)-3-methyl-2-oxopentanoyl]amino group at position 18. It acts as a proteasome inhibitor and is isolated from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. | TMC-95B |
| tryprostatin a | A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at positions 2 and 6 on the indole ring by prenyl and methoxy groups respectively. | tryprostatin A |
| tryprostatin b | A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at position 2 on the indole ring by a prenyl group. | tryprostatin B |
| varespladib | A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects. | varespladib |
| varespladib methyl | A methyl ester resulting from the formal condensation of the carboxy group of varespladib with methanol. It is a potential therapy for the treatment of snakebite envenomings in which toxicity depends on the action of PLA2s. | varespladib methyl |
| vilazodone | A 1-benzofuran that is 5-(piperazin-1-yl}-1-benzofuran-2-carboxamide having a (5-cyanoindol-3-yl)butyl group attached at position N-4 on the piperazine ring. Used for the treatment of major depressive disorder. | vilazodone |
| wasalexin a | | Wasalexin A |
| way-362450 | | turofexorate isopropyl |