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paraben

A 4-hydroxybenzoate ester in which the esterifying alcohol is an alkanol (in diagram, R = alkyl). Commonly used as preservatives in cosmetic and pharmaceutical products.

ChEBI ID: 85122

Members (3)

MemberDefinitionRole
ethyl-p-hydroxybenzoateAn ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol,ethylparaben
methylparabenA 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.methylparaben
propylparabenThe benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.propylparaben

Research

Studies (2,564)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990389 (15.17)18.7374
1990's223 (8.70)18.2507
2000's497 (19.38)29.6817
2010's953 (37.17)24.3611
2020's502 (19.58)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials38 (1.14%)5.53%
Reviews122 (3.66%)6.00%
Case Studies80 (2.40%)4.05%
Observational4 (0.12%)0.25%
Other3,088 (92.68%)84.16%