Any purine ribonucleoside that is a derivative of adenosine.
ChEBI ID: 22260
| Member | Definition | Role |
|---|---|---|
| 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and the hydrogen at position 2 on the adenine is replaced by a 4-(2-carboxyethyl)phenethylamino group. | CGS-21680 |
| 2-fluoroadenosine | 2-fluoroadenosine | |
| 2'-deoxy-2-fluoroadenosine | 2'-deoxy-2-fluoroadenosine | |
| 2'-o-methyladenosine | A member of the class of adenosines that is adenosine in which the hydroxy group at position 2' is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis. | cordysinin B |
| 3-iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodo-4-aminobenzyl group. | 3-iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine |
| 5'-chloro-5'-deoxyadenosine | 5'-chloro-5'-deoxyadenosine | |
| 5'-deoxyadenosine | A 5'-deoxyribonucleoside compound having adenosine as the nucleobase. | 5'-deoxyadenosine |
| adenosine | A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond. | adenosine |
| adenosine-5'-(n-ethylcarboxamide) | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by an N-ethylcarboxamido group. | N-ethyl-5'-carboxamidoadenosine |
| adenosine-5'-(N-propyl)carboxamide | A monocarboxylic acid amide that is the propyl amide of adenosine 5'-carboxylic acid. | adenosine-5'-(N-propyl)carboxamide |
| adenosine-5'-carboxaldehyde | A member of the class of adenosines that is 5'-dehydro derivative of adenosine. | 5'-dehydroadenosine |
| clofarabine | A purine nucleoside analogue consisting of a 6-amino-2-chloropurin-9-yl group attached to the 1beta position of 2'-deoxy-2'-fluoro-D-arabinofuranose. It is metabolized intracellularly to the active 5'-triphosphate metabolite, which inhibits DNA synthesisis and so stops the growth of cancer cells. Clofarabine is used as an antimetabolite antineoplastic agent in the treatment of relapsed or refractory acute lymphoblastic leukaemia. | clofarabine |
| cordycepin | cordycepin | |
| dideoxyadenosine | A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine. | 2',3'-dideoxyadenosine |
| n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group. | 3-iodobenzyl-5'-N-methylcarboxamidoadenosine |
| nucleocidin | A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. | nucleocidin |
| puromycin aminonucleoside | Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine |
| s-adenosyl-3-methylthiopropylamine | The S-adenosyl derivative of methioninamine. It acts as the aminopropyl donor in the biosynthesis of the polyamines, spermidine and spermine. | S-adenosylmethioninamine |
| s-adenosylhomocysteine | An organic sulfide that is the S-adenosyl derivative of L-homocysteine. | S-adenosyl-L-homocysteine zwitterion; S-adenosyl-L-homocysteine |
| sinefungin | An adenosine that is the the delta-(5'-adenosyl) derivative of ornithine. | sinefungin |
| succinyladenosine | An aspartic acid derivative that is L-aspartic acid in which one of the amine hydrogens is substituted by a 9-beta-D-ribofuranosyl-9H-purin-6-yl group. | succinyladenosine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8,649 (24.84) | 18.7374 |
| 1990's | 8,195 (23.53) | 18.2507 |
| 2000's | 7,075 (20.32) | 29.6817 |
| 2010's | 7,655 (21.98) | 24.3611 |
| 2020's | 3,251 (9.34) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,212 (3.09%) | 5.53% |
| Reviews | 3,098 (7.91%) | 6.00% |
| Case Studies | 682 (1.74%) | 4.05% |
| Observational | 115 (0.29%) | 0.25% |
| Other | 34,077 (86.97%) | 84.16% |