Fractures, Compound

Fractures in which there is an external wound communicating with the break of the bone.

Synonym
Fractures, Open
Fractures, Compound

Excerpt	Reference
"When severe open fractures are managed with the antibiotic bead pouch technique, wound closure should be obtained within one week to prevent infectious complications."	( Ekkernkamp, A; Henry, SL; Ostermann, PA; Seligson, D, 1994)
"Open fractures are plagued by high complication rates, among which infection and nonunion are the most common, leading to higher morbidity and poor patient outcomes."	( Guelcher, SA; Wenke, JC, 2011)
"Open fractures are often complicated by infection."	( Akers, KS; Shiels, SM; Tennent, DJ; Wenke, JC, 2017)
"Open fractures are at significant risk of developing a fracture-related infection, despite the routine administration of perioperative antibiotic prophylaxis."	( Arens, D; D'Este, M; Deimling, C; Eglin, D; Metsemakers, WJ; Morgenstern, M; Moriarty, TF; Puetzler, J; Richards, RG; Vallejo Diaz, A; Zeiter, S, 2020)

Excerpt	Reference
"The most serious complications in the treatment of open fractures and after procedures on bone tissue are infections."	( Kateusz, J; Misterka, S, 1992)
"A consecutive series of 119 type III B compound fractures in 103 patients was treated at the University of Louisville from May 1983 to May 1989."	( Ekkernkamp, A; Henry, SL; Ostermann, PA; Seligson, D, 1992)
"In a consecutive series of 222 compound fractures treated at the University of Louisville Level I Trauma Center from November 1984 to January 1987, 21 severe compound tibia shaft fractures in 20 patients were managed with the antibiotic bead pouch technique."	( Henry, SL; Ostermann, PA; Seligson, D, 1989)
"For the treatment of 25 open fractures - the wooden fixation proved to be the best solution."	( Domres, B; Klöss, T, 1984)
"Seven hundred four compound fractures (198 [28%] Grade I, 259 [37%] Grade II, and 247 [35%] Grade III) were treated during a seven-year period at the author's institution."	( Henry, SL; Ostermann, PA; Seligson, D, 1993)
"Seven hundred and four compound fractures--198 (28%) grade I, 259 (37%) grade II, 247 (35%) grade III (86 IIIA, 119 IIIB, 42 IIIC)--were treated in 590 patients between May 1983 and May 1989 at the University of Louisville."	( Henry, SL; Ostermann, PA; Seligson, D, 1993)
"Modern principles for the treatment of open fractures include stabilisation of the bone and management of the soft tissues."	( Crowley, DJ; Giannoudis, PV; Kanakaris, NK, 2007)
"Antibiotic administration during the treatment of open fractures has been shown to reduce infection rates and is considered a critical step in the management of these injuries."	( Banks, K; Hahn, J; Inaba, K; Marecek, GS; Pannell, WC, 2016)
"Gentamicin use during the treatment of open fractures does not lead to increased rates of renal dysfunction when used in patients with normal baseline renal function."	( Banks, K; Hahn, J; Inaba, K; Marecek, GS; Pannell, WC, 2016)
"In the treatment of open fractures complicated with soft tissue injury, cefazolin sodium pentahydrate combined with VSD can effectively reduce inflammation and stress, thus improving the treatment efficacy."	( Che, B; Lou, W; Qin, S; Wang, K; Yu, Z; Zou, K, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	188 (35.61)	23.3326
1990's	92 (17.42)	12.5806
2000's	91 (17.23)	18.1394
2010's	112 (21.21)	28.8240
2020's	45 (8.52)	9.53

Drug	Relationship Strength	Studies	Trials
methane	low	1	0
salicylic acid	low	3	0
aminocaproic acid	low	2	0
lactic acid	low	2	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	2	0
iodine	low	2	0
methanol	low	4	0
nitrous oxide	low	1	0
phenol	low	2	0
urea	medium	2	1
6-acetylaminocaproic acid	low	2	0
amiodarone	low	1	0
amlodipine	low	1	0
aspirin	low	1	0
bupivacaine	low	3	0
camphor, (+-)-isomer	low	1	0
cefuroxime	medium	5	1
ciprofloxacin	medium	3	1
erythrosine	low	2	0
fentanyl	low	1	0
fluconazole	low	1	0
furazolidone	low	1	0
gentamicin	medium	38	4
halothane	low	1	0
lidocaine	low	2	0
2-propanol	medium	1	1
mafenide	low	1	0
metronidazole	low	2	0
miconazole	low	1	0
norfloxacin	low	1	0
ofloxacin	medium	3	2
potassium iodide	low	1	0
procaine	low	4	0
sulfadiazine	medium	1	1
succinylcholine	low	1	0
sulfanilamide	low	1	0
thalidomide	low	1	0
tolazoline	low	1	0
tranexamic acid	low	1	0
floxuridine	low	1	0
3,3',5-triiodothyroacetic acid	low	1	0
penicillin g	medium	6	2
triiodothyronine	low	1	0
biguanides	low	1	0
sucrose	low	1	0
cephalothin	medium	7	1
carbostyril	low	2	0
phenylephrine	low	1	0
cloxacillin	medium	3	3
oxacillin	medium	1	1
ampicillin	medium	3	1
isoprene	low	2	0
methylmethacrylate	low	1	0
penicillanic acid	low	2	0
framycetin	low	1	0
sulfan blue	low	1	0
fusarium	low	1	0
dihydroergotamine	low	1	0
c.i. 42510	low	1	0
erythromycin	low	2	0
calcium citrate	low	1	0
durapatite	low	4	0
vancomycin	medium	25	2
d-alpha tocopherol	low	1	0
fluorescein	low	1	0
dicloxacillin	medium	2	2
streptomycin	medium	7	1
vantocil	low	1	0
floxacillin	medium	2	2
silver	medium	5	2
tantalum	medium	2	1
technetium	low	2	0
titanium	medium	16	2
calcium phosphate, dibasic, anhydrous	low	2	0
calcium phosphate, monobasic, anhydrous	low	2	0
tricalcium phosphate	low	7	0
calcium sulfate	medium	8	2
trolamine salicylate	low	20	0
clodronic acid	low	1	0
cephalexin	medium	5	1
triamcinolone	low	1	0
transferrin	low	1	0
cefazolin	medium	29	5
amoxicillin	low	1	0
tobramycin	medium	22	1
amikacin	low	5	0
cephradine	medium	4	1
propiconazole	low	8	0
cefonicid	medium	1	1
piperacillin	low	2	0
pefloxacin	medium	1	1
fomesafen	low	1	0
cefotetan	low	1	0
cephalosporin c	medium	17	4
triazoles	low	2	0
fluorodeoxyglucose f18	low	2	0
zoledronic acid	low	2	0
voriconazole	low	2	0
oxazolidin-2-one	low	1	0
clarithromycin	low	1	0
nicotine	low	1	0
fibrinogen	low	1	0
tazobactam	low	2	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
sulbactam	low	1	0
beta-lactams	low	1	0
ertapenem	low	1	0
calcium pyrophosphate	low	2	0
ropivacaine	low	1	0
1-(chloromethyl)silatrane	low	1	0
povidone-iodine	medium	4	3
fibrin	low	1	0
inositol 3-phosphate	low	2	0
meropenem	low	2	0
cefoxitin	low	1	0
linezolid	low	1	0
retinol	low	1	0
clindamycin	medium	6	3
h 89	low	1	0
cefamandole	medium	1	1
lincomycin	low	1	0
freedom	low	1	0
quercetin	low	1	0
vitamin k semiquinone radical	low	2	0
cholecalciferol	low	1	0
amphotericin b	low	3	0
phenylephrine hydrochloride	low	1	0
bismuth	low	1	0
cefotaxime	medium	1	1
4-(4-dihexadecylaminostyryl)-n-methylpyridium	low	1	0
furagin	low	1	0
chlorhexidine	medium	6	2
amoxicillin-potassium clavulanate combination	low	1	0
indocyanine green	low	3	0
virginiamycin	low	1	0
rifamycins	low	1	0
endothelin-1	low	1	0
chitosan	low	3	0
ro13-9904	medium	7	2
piperacillin, tazobactam drug combination	low	1	0
interleukin-8	low	2	0
ascorbic acid	low	1	0
tetracycline	low	2	0
chlortetracycline	low	1	0
acenocoumarol	low	1	0
warfarin	low	1	0
tigecycline	low	1	0
transforming growth factor beta	medium	13	4
technetium tc 99m sulfur colloid	low	1	0
hyaluronoglucosaminidase	low	1	0
daptomycin	low	1	0
technetium tc 99m medronate	low	1	0
muramidase	low	1	0
chondroitin sulfates	low	1	0
vitamin a, vitamin e, vitamin k3 drug combination	low	1	0
exudates	low	3	0
levoleucovorin	low	1	0
rifampin	low	3	0
eye	low	1	0

Protein Targets (1,180)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
RAR-related orphan receptor gamma	22	0	0	22
GLI family zinc finger 3	21	0	0	21
AR protein	35	0	0	35
aldehyde dehydrogenase 1 family, member A1	25	0	0	25
retinoic acid nuclear receptor alpha variant 1	22	0	0	22
retinoid X nuclear receptor alpha	23	0	0	23
estrogen nuclear receptor alpha	47	0	0	47
peroxisome proliferator-activated receptor delta	17	0	0	17
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	16	0	0	16
activating transcription factor 6	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
Histone H2A.x	13	0	0	13
thyroid hormone receptor beta isoform a	12	0	0	12
heat shock protein beta-1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	32	0	0	32
lamin isoform A-delta10	28	0	0	28
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Glutamate receptor 2	10	0	0	10
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
SMAD family member 2	10	0	0	10
USP1 protein, partial	13	0	0	13
SMAD family member 3	10	0	0	10
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
estrogen receptor 2 (ER beta)	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	13	0	0	13
progesterone receptor	13	0	0	13
glucocorticoid receptor [Homo sapiens]	29	0	0	29
estrogen-related nuclear receptor alpha	28	0	0	28
farnesoid X nuclear receptor	16	0	0	16
peroxisome proliferator activated receptor gamma	20	0	0	20
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	30	0	0	30
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
cytochrome P450 2C9 precursor	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
vitamin D3 receptor isoform VDRA	15	0	0	15
thyroid hormone receptor beta isoform 2	23	0	0	23
DNA polymerase beta	4	0	0	4
geminin	30	0	0	30
survival motor neuron protein isoform d	7	0	0	7
histone acetyltransferase KAT2A isoform 1	12	0	0	12
Cellular tumor antigen p53	22	0	0	22
Androgen receptor	0	2	0	2
Thyroid hormone receptor alpha	0	4	2	6
Thyroid hormone receptor beta	0	4	2	6
Proliferating cell nuclear antigen	0	2	0	2
Thyroid hormone receptor beta	0	3	0	3
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Histamine H2 receptor	8	0	0	8
Sodium/bile acid cotransporter	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	1	4
5-hydroxytryptamine receptor 2A	0	3	1	4
5-hydroxytryptamine receptor 1A	0	8	1	9
5-hydroxytryptamine receptor 1B	0	5	1	6
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	3	1	4
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	4	1	5
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	14	0	0	14
Luciferase	10	0	0	10
G	11	0	0	11
thyroid stimulating hormone receptor	11	0	0	11
chromobox protein homolog 1	20	0	0	20
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
muscleblind-like protein 1 isoform 1	5	0	0	5
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Guanine nucleotide-binding protein G	4	0	0	4
Inositol hexakisphosphate kinase 1	11	0	0	11
cytochrome P450 2C9, partial	11	0	0	11
peripheral myelin protein 22	14	0	0	14
ATP-binding cassette sub-family C member 3	0	29	0	29
Multidrug resistance-associated protein 4	0	29	0	30
Bile salt export pump	0	44	0	44
Canalicular multispecific organic anion transporter 1	0	29	0	29
Aminoglycoside 3'-phosphotransferase	0	0	0	2
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, PLASMINOGEN	0	0	2	2
Chain A, PLASMINOGEN	0	0	2	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
Chain A, Ferritin light chain	8	0	0	8
Chain A, Apolipoprotein	0	0	1	1
15-lipoxygenase, partial	6	0	0	6
ATAD5 protein, partial	7	0	0	7
regulator of G-protein signaling 4	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	19	0	0	19
EWS/FLI fusion protein	19	0	0	19
nonstructural protein 1	2	0	0	2
arylsulfatase A	6	0	0	6
D(1A) dopamine receptor	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
Rap guanine nucleotide exchange factor 3	6	0	0	6
Plasminogen	0	4	2	6
Proton-coupled amino acid transporter 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
acetylcholinesterase	11	0	0	11
phosphopantetheinyl transferase	10	0	0	10
Fumarate hydratase	4	0	0	4
NFKB1 protein, partial	4	0	0	4
PPM1D protein	3	0	0	3
TDP1 protein	30	0	0	30
Thrombopoietin	1	0	0	1
caspase 7, apoptosis-related cysteine protease	5	0	0	5
thyroid stimulating hormone receptor	15	0	0	15
pregnane X nuclear receptor	25	0	0	25
cytochrome P450 2D6	12	0	0	12
polyprotein	4	0	0	4
caspase-3	5	0	0	5
cytochrome P450 2D6 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
huntingtin isoform 2	3	0	0	3
mitogen-activated protein kinase 1	9	0	0	9
flap endonuclease 1	7	0	0	7
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
nuclear receptor ROR-gamma isoform 1	8	0	0	8
cytochrome P450 3A4 isoform 1	9	0	0	9
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	9	3	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	1	0	7
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	3	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	6	0	6
Lysine-specific demethylase PHF2	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Integrin beta-3	5	1	0	6
Tyrosine-protein kinase Fyn	0	2	0	2
ATP-dependent translocase ABCB1	0	7	0	7
Aldo-keto reductase family 1 member B1	0	5	0	5
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	4	0	4
ATP-dependent translocase ABCB1	0	12	2	15
Integrin alpha-IIb	5	1	0	6
Beta-1 adrenergic receptor	0	4	1	5
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	10	1	11
Adenosine receptor A3	0	5	0	5
Cytochrome P450 2C8	0	2	0	2
Muscarinic acetylcholine receptor M1	0	4	0	4
Beta-3 adrenergic receptor	0	4	1	5
D(2) dopamine receptor	0	7	0	7
Androgen receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	9	3	1	14
Alpha-1B adrenergic receptor	0	9	2	11
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	7	1	8
Gamma-aminobutyric acid receptor subunit delta	9	3	1	14
Gamma-aminobutyric acid receptor subunit gamma-2	9	3	1	14
Gamma-aminobutyric acid receptor subunit alpha-5	9	3	1	14
Gamma-aminobutyric acid receptor subunit alpha-3	9	3	1	14
Muscarinic acetylcholine receptor M3	0	4	0	4
ATP-dependent translocase ABCB1	0	7	0	7
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	6	0	6
D(4) dopamine receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	9	3	1	14
Gamma-aminobutyric acid receptor subunit alpha-2	9	3	1	14
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
Histamine H2 receptor	0	4	0	4
Endothelin-1 receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	9	3	1	14
Gamma-aminobutyric acid receptor subunit gamma-3	9	3	1	14
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	9	3	1	14
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	4	0	4
Mu-type opioid receptor	0	6	1	7
D(3) dopamine receptor	0	7	0	7
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	6	0	6
Kappa-type opioid receptor	0	6	0	6
5-hydroxytryptamine receptor 2B	0	6	0	6
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	8	2	10
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	8	0	8
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	3	0	3
Spike glycoprotein	10	0	1	11
Gamma-aminobutyric acid receptor subunit alpha-1	9	4	1	15
Gamma-aminobutyric acid receptor subunit beta-3	9	3	1	14
Gamma-aminobutyric acid receptor subunit beta-2	9	3	1	14
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Sodium-dependent dopamine transporter	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	13	0	14
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Sodium channel protein type 5 subunit alpha	0	2	0	2
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	9	3	1	14
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Ataxin-2	7	0	0	7
Sigma non-opioid intracellular receptor 1	0	4	1	5
Gamma-aminobutyric acid receptor subunit epsilon	9	3	1	14
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
acid sphingomyelinase	4	0	0	4
Smad3	6	0	0	6
IDH1	9	0	0	9
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
Potassium channel subfamily K member 2	0	2	2	4
Alpha-2C adrenergic receptor	0	5	1	6
Alpha-2B adrenergic receptor	0	4	2	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	4	2	6
Alpha-2A adrenergic receptor	0	4	2	6
Alpha-1D adrenergic receptor	0	5	1	6
Alpha-1A adrenergic receptor	0	2	2	4
Alpha-1B adrenergic receptor	0	2	2	4
Potassium channel subfamily K member 2	0	1	0	1
Chain A, Beta-lactamase	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Beta-lactamase	0	1	0	6
Beta-lactamase	0	1	0	7
Beta-lactamase	0	0	0	8
Beta-lactamase	0	2	0	10
apical membrane antigen 1, AMA1	7	0	0	7
Beta-lactamase	0	0	0	5
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	14	0	0	14
DNA polymerase kappa isoform 1	11	0	0	11
Bile salt export pump	0	9	0	9
Beta-lactamase SHV-1	0	1	0	7
Beta-lactamase SHV-1	0	3	0	11
Cytochrome P450 2C9	0	12	1	14
Beta-lactamase	0	2	0	10
Kappa-type opioid receptor	0	3	0	9
Solute carrier family 15 member 1	0	20	0	20
Solute carrier family 15 member 1	0	4	0	5
Cytochrome P450 2J2	0	4	0	4
B2 metallo-beta-lactamase	0	0	0	7
Solute carrier family 15 member 2	0	11	0	11
Beta-lactamase	0	1	0	7
Beta-lactamase	0	0	0	6
Solute carrier family 15 member 2	0	12	0	13
Beta-lactamase	0	1	0	7
Beta-lactamase	0	0	0	6
Chain A, Cruzipain	9	0	0	9
interleukin 8	8	0	0	8
GLS protein	8	0	0	8
tumor necrosis factor	1	0	0	1
Cytochrome P450 1A2	0	6	0	7
Cytochrome P450 3A4	0	12	0	13
Cytochrome P450 2D6	0	5	0	6
Cytochrome P450 2C19	0	5	0	6
Nuclear receptor ROR-gamma	7	0	0	7
Aurora kinase B	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	1	4
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	3	0	7
Beta-lactamase	0	2	0	7
Beta-lactamase	0	1	0	8
Metallo-beta-lactamase type 2	0	0	1	8
Metallo-beta-lactamase VIM-11	0	0	0	6
Metallo-beta-lactamase VIM-2	0	0	0	6
Beta-lactamase	0	1	0	9
Metallo-beta-lactamase	0	0	0	7
Beta-lactamase	0	2	0	7
Carbonic anhydrase 1	0	15	0	17
Carbonic anhydrase 2	0	17	2	21
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	5
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	0	0	6
Efflux transporter	0	1	0	5
Beta-lactamase	0	1	0	7
Beta-lactamase Toho-1	0	0	0	5
Beta-lactamase	0	1	0	5
Class D beta-lactamase	0	2	0	6
60 kDa chaperonin	0	5	0	5
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	8
Beta-lactamase	0	0	1	4
10 kDa chaperonin	0	5	0	5
Metallo-b-lactamase	0	0	0	12
Carbapenem-hydrolyzing beta-lactamase KPC	0	3	0	11
Histamine H3 receptor	0	0	0	6
Beta-lactamase class B VIM-2	0	0	1	13
Beta-lactamase VIM-1	0	0	0	6
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Polyphenol oxidase 2	0	3	0	6
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thioredoxin reductase	18	0	0	18
hypothetical protein, conserved	3	0	0	3
glucocerebrosidase	4	0	0	4
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Bloom syndrome protein isoform 1	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	10	0	10
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	3	0	3
Fatty acid-binding protein, liver	0	1	0	1
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	3	0	3
Adenosine receptor A2a	0	3	0	3
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	1	2
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
ATPase family AAA domain-containing protein 5	6	0	0	6
67.9K protein	5	0	0	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, serum paraoxonase	0	1	0	1
Carbonic anhydrase 12	0	7	0	7
Carbonic anhydrase 3	0	6	0	6
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 4	0	7	0	7
Carbonic anhydrase 6	0	9	0	9
Carbonic anhydrase 5A, mitochondrial	0	9	0	10
Carbonic anhydrase 7	0	6	0	6
Carbonic anhydrase 9	0	10	1	11
Carbonic anhydrase 13	0	3	0	3
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	7	0	7
Carbonic anhydrase 5B, mitochondrial	0	6	0	7
Solute carrier family 22 member 6	0	8	0	8
Solute carrier family 22 member 7	0	4	0	5
Solute carrier family 22 member 8	0	7	0	8
Solute carrier family 22 member 11	0	5	0	6
Solute carrier family 22 member 8	0	7	0	8
Solute carrier family 22 member 7	0	4	0	5
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Beta-lactamase	0	3	0	7
Beta-lactamase	0	2	0	5
Metallo-beta-lactamase VIM-19	0	0	0	6
Beta-lactamase	0	2	0	7
Albumin	0	2	7	9
Beta-lactamase	0	0	0	3
Beta-lactamase	0	2	0	7
Metallo-beta-lactamase VIM-2	0	0	0	6
BlaVIM-1	0	0	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	5
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3A isoform a	0	1	0	1
TAR DNA-binding protein 43	7	0	0	7
Solute carrier family 22 member 8	0	8	0	9
Microtubule-associated protein tau	10	0	0	10
Beta-lactamase	0	0	0	2
aryl hydrocarbon receptor	12	0	0	12
Beta-lactamase	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	2	0	5
Beta-lactamase	0	4	0	9
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	7	0	11
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	3
endonuclease IV	1	0	0	1
WRN	1	0	0	1
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
importin subunit beta-1 isoform 1	4	0	0	4
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	4	0	0	4
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Beta-lactamase OXA-1	0	2	0	4
Beta-lactamase	0	1	0	5
phosphoglycerate kinase	3	0	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
PAX8	0	0	0	1
glp-1 receptor, partial	9	0	0	9
pregnane X receptor	3	0	0	3
PINK1	1	0	0	1
Parkin	2	0	0	2
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cytochrome P450 2C19 precursor	3	0	0	3
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
protein AF-9 isoform a	0	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 1	0	2	0	3
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
72 kDa type IV collagenase	0	5	0	5
Matrix metalloproteinase-9	0	4	0	4
Trypanothione reductase	0	1	0	1
Alpha-synuclein	2	4	0	6
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Rap guanine nucleotide exchange factor 4	3	0	0	3
Multidrug and toxin extrusion protein 1	0	5	0	5
Spermine oxidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	6	0	6
60 kDa chaperonin	0	2	0	2
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	1	1
Vitamin D3 receptor	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	4	0	7
DNA gyrase subunit B	0	4	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	2	2
DNA gyrase subunit B	0	3	0	4
DNA gyrase subunit A	0	4	0	5
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
streptokinase A precursor	0	0	8	8
Solute carrier organic anion transporter family member 1B3	0	3	0	5
Solute carrier organic anion transporter family member 1B1	0	3	0	5
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
Stromelysin-1	0	3	1	4
Macrophage metalloelastase	0	2	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
dopamine D1 receptor	2	0	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
Replicase polyprotein 1ab	0	3	1	4
Replicase polyprotein 1ab	0	4	1	5
Alpha-1D adrenergic receptor	0	4	2	6
Cereblon isoform 4	0	4	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	5	1	7
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
Cytochrome P450 1B1	0	3	1	4
Lanosterol 14-alpha demethylase	0	5	1	6
50S ribosomal protein L36 2	0	4	1	5
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	4
Amine oxidase [flavin-containing] B	0	3	0	3
Delta-type opioid receptor	0	5	0	5
Delta-type opioid receptor	0	5	0	5
Mu-type opioid receptor	0	5	1	6
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	2	1	3
interferon gamma precursor	0	0	0	2
Sodium/nucleoside cotransporter 2	0	1	0	1
Thymidylate synthase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine kinase	0	0	0	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	4
Histone deacetylase 3	0	1	0	1
Chymotrypsinogen A	0	3	0	3
Beta-lactamase	0	5	0	5
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Heme oxygenase 1	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	2	3
Aromatase	0	3	0	3
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	2	0	2
Histone deacetylase 4	0	1	0	1
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	2	2
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	2	2
Histone deacetylase 1	0	1	0	1
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
14-alpha sterol demethylase	0	0	2	2
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
heat shock protein 90, putative	0	0	0	3
likely tRNA 2'-phosphotransferase	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	2	2
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Chain E, C-amp-dependent Protein Kinase	0	1	0	1
Chain I, Protein Kinase Inhibitor Peptide	0	1	0	1
Chain E, C-amp-dependent Protein Kinase	0	1	0	1
Chain E, C-amp-dependent Protein Kinase	0	1	0	1
Chain I, Protein Kinase Inhibitor Peptide	0	1	0	1
Rho-associated protein kinase 2	0	1	1	2
Ribosomal protein S6 kinase alpha-5	0	1	0	1
Serine/threonine-protein kinase D3	0	1	0	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Protein kinase C gamma type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	1	2
Protein kinase C beta type	0	1	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Protein kinase C alpha type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Casein kinase II subunit alpha'	0	3	0	3
cAMP-dependent protein kinase catalytic subunit gamma	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	0	1
Ribosomal protein S6 kinase beta-1	0	1	0	1
Protein kinase C eta type	0	1	0	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	3	0	3
RAC-beta serine/threonine-protein kinase	0	1	0	1
Protein kinase C iota type	0	1	0	1
G protein-coupled receptor kinase 6	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	0	2
Casein kinase II subunit beta	0	3	0	3
Casein kinase II subunit alpha	0	3	0	3
Casein kinase I isoform gamma-2	0	1	0	1
MO15-related protein kinase Pfmrk	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	2	0	2
cGMP-dependent protein kinase 1	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Myosin light chain kinase 3	0	1	0	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	1	0	1
Casein kinase I isoform gamma-1	0	1	0	1
RAC-gamma serine/threonine-protein kinase	0	1	0	1
histone deacetylase 9 isoform 3	3	0	0	3
Replicase polyprotein 1ab	0	1	1	2
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Estrogen receptor	0	0	1	1
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	1	1
Renin	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	3	0	3
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 15	0	4	0	4
Carbonic anhydrase 13	0	5	0	5
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Vpr	4	0	0	4
Metabotropic glutamate receptor 6	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Acetylcholinesterase	0	4	0	4
Aromatase	0	0	1	1
Thromboxane-A synthase	0	1	0	1
Substance-P receptor	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	4	0	4
Type-2 angiotensin II receptor	0	2	0	2
Cholinesterase	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
methionyl-tRNA synthetase, putative	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	2	6
Muscarinic acetylcholine receptor M2	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	1	2	2	6
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Translocator protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Inositol monophosphatase 1	2	0	0	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	2	1	4
neuropeptide S receptor isoform A	3	0	0	3
STE24	0	0	0	1
Trypsin	0	0	0	1
MecA	0	1	0	1
Beta-lactamase 1	0	0	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
alpha-galactosidase	1	0	0	1
Endolysin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Cannabinoid receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 3	0	3	0	3
Alpha-1B adrenergic receptor	0	0	1	1
ras-related protein Rab-9A	1	0	0	1
Beta-2 adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
GALC protein	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
Spike glycoprotein	0	0	1	1
galactokinase	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
Transmembrane protease serine 2	0	0	1	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	2	3
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Cytochrome P450 1A1	0	2	1	3
Amyloid-beta precursor protein	0	2	0	2
Tyrosine-protein kinase Lck	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Procathepsin L	0	0	1	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
Hepatocyte growth factor receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Urease subunit alpha	0	3	0	3
Serine/threonine-protein kinase B-raf	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Beta-secretase 1	0	2	0	2
Anthrax toxin receptor 2	0	1	0	1
Urease subunit beta	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Substance-K receptor	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Beta-lactamase	0	2	0	2
Metallo-beta-lactamase type 2	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Aurora kinase A	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
Protein argonaute-2	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Trace amine-associated receptor 1	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
Farnesyl pyrophosphate synthase	0	2	0	2
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (528)

Protein Targets (1,180)

Fractures, Compound

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (528)

Drugs Studied (179)

Protein Targets (1,180)