Page last updated: 2024-08-05 10:55:43
aminoalkylpyridine
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ChEBI ID: 38198
Members (4)
Member | Definition | Role |
---|---|---|
2-(2-aminoethyl)pyridine | An aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2. | 2-pyridylethylamine |
betahistine | An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease. | betahistine |
pyridoxamine | A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. | pyridoxamine |
pyridoxamine phosphate | A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. | pyridoxamine 5'-phosphate |
Research
Studies (1,219)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 459 (37.65) | 18.7374 |
1990's | 146 (11.98) | 18.2507 |
2000's | 260 (21.33) | 29.6817 |
2010's | 270 (22.15) | 24.3611 |
2020's | 84 (6.89) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 137 (9.42%) | 5.53% |
Reviews | 103 (7.08%) | 6.00% |
Case Studies | 23 (1.58%) | 4.05% |
Observational | 2 (0.14%) | 0.25% |
Other | 1,190 (81.79%) | 84.16% |