Burning Mouth Syndrome

A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree of functional overlay; it is not limited to the psychophysiologic group of disorders.

Synonym
Burning Mouth Syndrome

Excerpt	Reference
"Burning mouth syndrome is an underdiagnosed and often poorly managed oral sensory disturbance."	( Savage, NW, 1996)
"Burning mouth syndrome is a debilitating disorder involving oral pain that may have at least 4 underlying causes."	( Emko, P; Kent, PF; Kurtz, DB; White, TL, 2004)
"Burning mouth syndrome is a relatively common condition."	( Maltsman-Tseikhin, A; Moricca, P; Niv, D, 2007)
"Burning mouth syndrome is a burning sensation or stinging disorder affecting the oral mucosa in the absence of any clinical signs or mucosal lesions."	( Capaccio, P; Marino, R; Pignataro, L; Spadari, F, 2009)
"Burning mouth syndrome is a chronic pain condition characterized by burning, painful sensations within the oral cavity."	( Friedman, DI, 2010)
"Burning mouth syndrome is a chronic pathology of unknown ethiopathogenesis."	( Messina, P; Provenzano, F; Ruggieri, A; Scardina, GA, 2010)
"Burning mouth syndrome is characterized by altered sensory qualities, namely tongue pain hypersensitivity."	( Honda, K; Iwata, K; Katagiri, A; Maruno, M; Satoh-Kuriwada, S; Shinoda, M; Shoji, N; Takeda, M; Tsuchiya, M, 2015)
"Burning mouth syndrome is defined as scorching sensation in the mouth in the absence of any local lesions or systemic disease that would explain that complaint."	( Cárcamo Fonfría, A; Cuadrado-Pérez, ML; Gómez-Vicente, L; Guerrero Peral, AL; Pedraza, MI; Porta-Etessam, J, 2017)
"Burning mouth syndrome is a condition of unknown aetiology that shares certain clinical patterns and treatment responses with restless leg syndrome."	( Cárcamo Fonfría, A; Cuadrado-Pérez, ML; Gómez-Vicente, L; Guerrero Peral, AL; Pedraza, MI; Porta-Etessam, J, 2017)
"Burning mouth syndrome is a chronic pain condition characterized by a burning sensation of the oropharynx."	( Chadwick, AL; Neuman, DL, 2021)
"Burning mouth syndrome is a chronic idiopathic intractable intraoral dysaesthesia that remains a challenge to clinicians due to its poorly understood pathogenesis and inconsistent response to various treatments."	( Hoffmann, J; Renton, T; Smith, JG; Tan, HL, 2022)
"Burning mouth syndrome is an intraoral chronic pain condition characterized by a moderate to severe sensation of burning from the oral mucosa."	( Aframian, DJ; Brotman, Y; Czerninski, R; Haviv, Y; Kay, Z; Klutstein, M; Merimsky, B; Sharav, Y, 2022)

Excerpt	Reference
"Burning mouth syndrome has been reported as being more common in Parkinson's disease patients than the general population."	( Coon, EA; Laughlin, RS, 2012)

Excerpt	Reference
"Burning mouth syndrome affects 1-3% of the population The exact mechanism is unknown."	( Hirsch, AR; Kim, AY; Lail, NS; Sharma, S; Ziad, A, 2011)

Excerpt	Reference
"Current treatment for burning mouth syndrome is usually directed at correction of detected organic causes or is empiric, and it often involves the use of tricyclic antidepressants."	( Epstein, J; Grushka, M; Mott, A, 1998)
"In the treatment of burning mouth syndrome (BMS), various approaches have been tried with equivocal results."	( Grushka, M; Heckmann, SM; Hummel, T; Kirchner, E; Wichmann, MG, 2012)
"Clonazepam has been used in the treatment of burning mouth syndrome (BMS) for several decades."	( Chen, FM; Chen, QM; Cui, Y; Jiang, L; Liu, JL; Xu, H; Zhou, Y, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	22 (7.46)	23.3326
1990's	36 (12.20)	12.5806
2000's	86 (29.15)	18.1394
2010's	115 (38.98)	28.8240
2020's	36 (12.20)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	13	1
ammonium hydroxide	low	1	0
citric acid, anhydrous	medium	6	1
chlorine	low	3	0
phloroglucinol	medium	1	1
gallic acid	low	1	0
glycerol	medium	1	1
histamine	low	1	0
dihydroxyphenylalanine	low	1	0
thioctic acid	medium	26	11
nickel	low	10	0
niacinamide	low	1	0
niacin	low	2	0
propylene glycol	medium	1	1
pyridoxine	low	3	0
sulfites	low	1	0
thiamine	low	4	0
urea	medium	1	1
menthol	low	1	0
dan 2163	medium	3	1
amitriptyline	medium	6	1
bethanechol	medium	1	1
bromazepam	low	1	0
bupivacaine	medium	2	1
caffeine	low	1	0
carbamazepine	medium	2	1
cetylpyridinium	medium	1	1
chlordiazepoxide	low	2	0
citalopram	low	1	0
desipramine	medium	1	1
diazepam	low	2	0
dyclonine	low	1	0
ethyl loflazepate	low	1	0
fentanyl	low	1	0
fluoxetine	medium	2	1
gabapentin	medium	10	1
hydroxychloroquine	medium	1	1
hypericin	medium	1	1
lidocaine	low	4	0
lamotrigine	low	1	0
mexiletine	low	1	0
miconazole	low	1	0
moclobemide	medium	1	1
muscimol	low	1	0
nevirapine	low	1	0
omeprazole	low	2	0
palmidrol	medium	1	1
prazepam	medium	1	1
procaine	low	1	0
sodium fluoride	medium	1	1
sulpiride	medium	3	1
trazodone	medium	1	1
thyroxine	low	1	0
prednisone	low	2	0
dehydroepiandrosterone	low	5	0
pilocarpine	low	1	0
biguanides	medium	1	1
sucrose	low	3	0
galactose	low	1	0
levodopa	low	4	0
medroxyprogesterone acetate	low	1	0
ethyl chloride	low	1	0
triamcinolone acetonide	low	2	0
pantothenic acid	low	2	0
methylmethacrylate	low	1	0
xylitol	medium	2	2
benzylamine	low	1	0
boric acid	medium	1	1
acrolein	low	1	0
thiophenes	low	3	0
1-naphthylamine	low	1	0
dydrogesterone	low	1	0
perylene	medium	1	1
betamethasone	low	1	0
medroxyprogesterone	low	1	0
trinitrobenzenesulfonic acid	low	1	0
acetylcysteine	low	1	0
benzydamine	medium	4	2
pimozide	low	1	0
mercury	low	8	0
palladium	low	4	0
cadmium	low	2	0
chromium	low	2	0
gold	low	4	0
mercuric chloride	low	1	0
ferric chloride	low	1	0
nickel sulfate	low	2	0
trolamine salicylate	medium	1	1
fluorides	low	1	0
phenyl acetate	low	1	0
cetylpyridinium chloride anhydrous	low	2	0
triamcinolone	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	low	2	0
tramadol	low	1	0
substance p	low	2	0
tocainide	low	1	0
propiconazole	low	1	0
paroxetine	medium	4	2
captopril	low	2	0
fomesafen	medium	3	1
fluorodopa f 18	low	1	0
aripiprazole	low	2	0
duloxetine hydrochloride	low	6	0
octyl gallate	low	1	0
milnacipran	low	3	0
sertraline	medium	4	1
trichlorosucrose	low	1	0
homocysteine	low	2	0
cobalt	low	3	0
carbidopa, levodopa drug combination	low	1	0
vitamin b 6	low	2	0
pramipexole	low	3	0
odapipam	low	1	0
benzofurans	low	1	0
inositol 3-phosphate	medium	6	2
hyperforin	medium	1	1
tibolone	medium	1	1
tretinoin	low	1	0
ferric hydroxide	low	1	0
cocaine	low	1	0
clindamycin	low	1	0
lycopene	medium	1	1
riboflavin	low	2	0
bromochloroacetic acid	low	1	0
cinnamaldehyde	low	1	0
sorbic acid	low	2	0
sodium metabisulfite	low	1	0
sb 366791	low	1	0
capsaicin	medium	24	8
D-fructopyranose	low	2	0
mercuric chloride, ammoniated	low	1	0
raclopride	low	1	0
quinine	low	2	0
cathepsin g	low	1	0
apigenin	medium	2	2
cholecalciferol	low	1	0
eprosartan	low	1	0
humulene	medium	1	1
lafutidine	medium	2	1
dothiepin hydrochloride	low	1	0
phenylephrine hydrochloride	low	1	0
oxycodone	low	1	0
topiramate	low	2	0
neurokinin a	low	1	0
naltrexone	low	2	0
lisinopril	low	1	0
ramipril	low	1	0
sulfur	low	1	0
enalapril	low	2	0
pepstatin	low	1	0
pregabalin	low	3	0
hypericum	medium	1	1
chlorhexidine	medium	4	3
f 13640	low	1	0
mocetinostat	low	1	0
vortioxetine	medium	2	2
nystatin a1	low	2	0
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc	low	1	0
acid phosphatase	low	1	0
jaw	low	3	0
tannins	low	1	0
cellulose	medium	2	2
phenylmercuric acetate	low	1	0
thimerosal	low	1	0
cardiovascular agents	low	1	0
piperidines	medium	3	1
interleukin-8	low	3	0
ascorbic acid	low	1	0
tetracycline	low	1	0
pyrethrins	low	1	0
vitamin b 12	low	9	0
cyclosporine	low	1	0
orabase	medium	1	1
muramidase	medium	3	2
acyclovir	low	1	0
folic acid	low	4	0
olanzapine	low	1	0
carbidopa	low	2	0

Protein Targets (1,357)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	25	0	0	25
Chain A, HADH2 protein	22	0	0	22
Chain B, HADH2 protein	22	0	0	22
RAR-related orphan receptor gamma	47	0	0	47
GLI family zinc finger 3	51	0	0	51
AR protein	63	0	0	63
aldehyde dehydrogenase 1 family, member A1	35	0	0	35
thyroid stimulating hormone receptor	17	0	0	17
estrogen receptor 2 (ER beta)	25	0	0	25
nuclear receptor subfamily 1, group I, member 3	41	0	0	41
progesterone receptor	31	0	0	31
glucocorticoid receptor [Homo sapiens]	50	0	0	50
retinoic acid nuclear receptor alpha variant 1	50	0	0	50
estrogen-related nuclear receptor alpha	50	0	0	50
pregnane X nuclear receptor	46	0	0	46
estrogen nuclear receptor alpha	68	0	0	68
aryl hydrocarbon receptor	26	0	0	26
thyroid stimulating hormone receptor	18	0	0	18
activating transcription factor 6	18	0	0	18
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	22	0	0	22
v-jun sarcoma virus 17 oncogene homolog (avian)	26	0	0	26
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	16	0	0	16
thyroid hormone receptor beta isoform 2	41	0	0	41
nuclear factor erythroid 2-related factor 2 isoform 1	50	0	0	50
cytochrome P450 3A4 isoform 1	21	0	0	21
Gamma-aminobutyric acid receptor subunit pi	21	11	1	33
Voltage-dependent calcium channel gamma-2 subunit	25	0	0	25
Gamma-aminobutyric acid receptor subunit beta-1	21	11	1	33
Gamma-aminobutyric acid receptor subunit delta	21	11	1	33
Gamma-aminobutyric acid receptor subunit gamma-2	21	11	2	34
Glutamate receptor 2	27	0	0	27
Gamma-aminobutyric acid receptor subunit alpha-5	21	11	1	33
Gamma-aminobutyric acid receptor subunit alpha-3	21	11	1	33
Gamma-aminobutyric acid receptor subunit gamma-1	21	11	1	33
Gamma-aminobutyric acid receptor subunit alpha-2	21	11	1	33
Gamma-aminobutyric acid receptor subunit alpha-4	21	11	1	33
Gamma-aminobutyric acid receptor subunit gamma-3	21	11	1	33
Gamma-aminobutyric acid receptor subunit alpha-6	21	11	1	33
Gamma-aminobutyric acid receptor subunit alpha-1	21	11	2	34
Gamma-aminobutyric acid receptor subunit beta-3	21	11	1	33
Gamma-aminobutyric acid receptor subunit beta-2	21	11	2	34
Kelch-like ECH-associated protein 1	0	0	1	1
GABA theta subunit	21	11	1	33
Gamma-aminobutyric acid receptor subunit epsilon	21	11	1	33
Histone acetyltransferase KAT8	0	1	0	1
5-hydroxytryptamine receptor 2C	0	11	1	12
5-hydroxytryptamine receptor 2A	0	12	1	13
5-hydroxytryptamine receptor 1A	0	18	2	22
5-hydroxytryptamine receptor 1B	0	10	1	11
5-hydroxytryptamine receptor 1D	0	4	1	5
5-hydroxytryptamine receptor 1F	0	4	1	5
5-hydroxytryptamine receptor 2B	0	10	1	11
5-hydroxytryptamine receptor 6	0	3	1	4
Sodium-dependent serotonin transporter	0	27	6	33
Sodium-dependent serotonin transporter	0	12	1	14
5-hydroxytryptamine receptor 7	0	5	1	6
5-hydroxytryptamine receptor 5A	0	3	1	4
5-hydroxytryptamine receptor 5B	0	3	1	4
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 4	0	3	1	4
5-hydroxytryptamine receptor 3B	0	3	1	4
Chain A, JmjC domain-containing histone demethylation protein 3A	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	19	0	0	19
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
acetylcholinesterase	24	0	0	24
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	13	0	0	13
pregnane X receptor	10	0	0	10
phosphopantetheinyl transferase	23	0	0	23
USP1 protein, partial	29	0	0	29
NFKB1 protein, partial	7	0	0	7
Microtubule-associated protein tau	22	0	0	22
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	17	0	0	17
retinoid X nuclear receptor alpha	38	0	0	38
farnesoid X nuclear receptor	29	0	0	29
vitamin D (1,25- dihydroxyvitamin D3) receptor	34	0	0	34
arylsulfatase A	15	0	0	15
euchromatic histone-lysine N-methyltransferase 2	49	0	0	49
Bloom syndrome protein isoform 1	17	0	0	17
D(1A) dopamine receptor	14	0	0	14
thyroid hormone receptor beta isoform a	22	0	0	22
heat shock protein beta-1	22	0	0	22
flap endonuclease 1	10	0	0	10
geminin	45	0	0	45
peripheral myelin protein 22	23	0	0	23
survival motor neuron protein isoform d	15	0	0	15
muscarinic acetylcholine receptor M1	15	0	0	15
Histone deacetylase 3	0	5	0	5
Solute carrier family 22 member 6	0	1	0	2
Histone deacetylase 4	0	4	0	4
Guanine nucleotide-binding protein G	3	0	0	3
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Ataxin-2	25	0	0	25
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
ATP-dependent phosphofructokinase	25	0	0	25
peroxisome proliferator activated receptor gamma	33	0	0	33
Transient receptor potential cation channel subfamily A member 1	0	0	3	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, Ferritin light chain	12	0	0	12
Thymidine kinase	0	1	0	1
thioredoxin reductase	23	0	0	23
GLS protein	24	0	0	24
TDP1 protein	47	0	0	47
Smad3	9	0	0	9
EWS/FLI fusion protein	22	0	0	22
Histone H2A.x	12	0	0	12
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lamin isoform A-delta10	45	0	0	45
Solute carrier family 22 member 1	0	12	0	15
ATP-binding cassette sub-family C member 3	0	39	0	39
Multidrug resistance-associated protein 4	0	39	0	40
Bile salt export pump	0	5	0	5
Bile salt export pump	0	54	0	54
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	16	3	19
Cytochrome P450 2J2	0	10	0	10
Disintegrin and metalloproteinase domain-containing protein 17	4	3	0	7
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Canalicular multispecific organic anion transporter 1	0	37	0	37
Thymidine kinase	0	1	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	36	0	0	36
nuclear receptor ROR-gamma isoform 1	27	0	0	27
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	13	5	18
Gamma-aminobutyric acid receptor subunit gamma-2	0	13	3	16
Cholecystokinin receptor type A	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	13	5	18
Gamma-aminobutyric acid receptor subunit alpha-3	0	13	4	17
Gamma-aminobutyric acid receptor subunit alpha-2	0	13	4	17
Gamma-aminobutyric acid receptor subunit beta-2	0	12	3	15
Cholecystokinin receptor type A	0	1	0	1
ATPase family AAA domain-containing protein 5	18	0	0	18
cytochrome P450 family 3 subfamily A polypeptide 4	41	0	0	41
cytochrome P450 2D6	32	0	0	32
cytochrome P450 2D6 isoform 1	16	0	0	16
chromobox protein homolog 1	31	0	0	31
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
Polyunsaturated fatty acid lipoxygenase ALOX15B	11	0	0	11
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	14	0	14
Albumin	0	0	5	5
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	13	0	13
Muscarinic acetylcholine receptor M2	0	15	1	16
Muscarinic acetylcholine receptor M4	0	12	0	12
Muscarinic acetylcholine receptor M1	0	4	0	5
Muscarinic acetylcholine receptor M3	0	3	0	4
Muscarinic acetylcholine receptor M4	0	3	0	4
Muscarinic acetylcholine receptor M5	0	3	0	4
Muscarinic acetylcholine receptor M5	0	13	0	13
Alpha-2A adrenergic receptor	0	16	0	16
Muscarinic acetylcholine receptor M2	0	3	0	4
Muscarinic acetylcholine receptor M1	0	15	3	18
Angiotensin-converting enzyme	0	21	0	22
D(2) dopamine receptor	0	22	5	28
Alpha-2B adrenergic receptor	0	15	1	16
Alpha-2C adrenergic receptor	0	12	0	12
Muscarinic acetylcholine receptor M3	0	14	0	14
D(1A) dopamine receptor	0	8	1	9
D(1B) dopamine receptor	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	1	0	3
Sodium-dependent noradrenaline transporter	0	21	4	25
Histamine H2 receptor	0	8	4	12
Alpha-1D adrenergic receptor	0	13	0	13
5-hydroxytryptamine receptor 2A	0	16	1	17
5-hydroxytryptamine receptor 2C	0	16	0	16
Histamine H1 receptor	0	4	1	5
Histamine H1 receptor	0	15	4	19
D(3) dopamine receptor	0	19	4	26
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	7	0	10
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 2B	0	18	0	18
Alpha-1A adrenergic receptor	0	15	0	15
Histamine H2 receptor	17	2	1	22
D(1A) dopamine receptor	6	1	0	7
5-hydroxytryptamine receptor 6	0	11	0	11
5-hydroxytryptamine receptor 7	0	4	0	4
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	17	3	20
Potassium voltage-gated channel subfamily H member 2	0	29	0	29
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Sodium channel protein type 5 subunit alpha	0	7	0	7
Sodium channel protein type 9 subunit alpha	0	9	0	9
Sigma non-opioid intracellular receptor 1	0	4	1	5
Nuclear receptor subfamily 3 group C member 3	0	13	0	13
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	20	0	20
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	6	2	8
Sodium channel protein type 10 subunit alpha	0	4	0	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	18	0	0	18
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, Cruzipain	8	0	0	8
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
Luciferase	14	0	0	14
interleukin 8	8	0	0	8
endonuclease IV	5	0	0	5
BRCA1	1	0	0	1
RGS12	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	17	0	0	17
ATAD5 protein, partial	14	0	0	14
PPM1D protein	7	0	0	7
apical membrane antigen 1, AMA1	8	0	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
G	23	0	0	23
Neuraminidase	0	2	0	2
67.9K protein	14	0	0	14
glucocerebrosidase	5	0	0	5
Parkin	6	0	0	6
peroxisome proliferator-activated receptor delta	27	0	0	27
pyruvate kinase	2	0	0	2
IDH1	20	0	0	20
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	10	0	0	10
Replicase polyprotein 1ab	0	1	2	3
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
peripheral myelin protein 22 isoform 1	7	0	0	7
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C19 precursor	10	0	0	10
cytochrome P450 2C9 precursor	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	18	0	0	18
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	9	0	0	9
histone deacetylase 9 isoform 3	3	0	0	3
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	20	0	0	20
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	14	0	0	14
DNA polymerase kappa isoform 1	17	0	0	17
M-phase phosphoprotein 8	7	0	0	7
pyruvate kinase PKM isoform b	1	0	0	1
neuropeptide S receptor isoform A	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	0	11	0	11
Gamma-aminobutyric acid receptor subunit delta	0	11	0	11
Polyphenol oxidase 2	0	5	0	6
Aldo-keto reductase family 1 member B10	0	3	0	3
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Lysozyme C-1	0	1	0	1
Cationic trypsin	0	1	0	1
Carbonic anhydrase 1	0	12	0	17
Carbonic anhydrase 2	0	14	2	22
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	23	0	0	23
Transthyretin	0	2	2	5
Estrogen receptor	0	5	1	6
Glucocorticoid receptor	0	12	2	15
Cellular tumor antigen p53	43	0	0	43
Cytochrome P450 1A1	0	3	0	3
Amyloid-beta precursor protein	0	4	0	4
Integrin beta-3	6	0	0	6
Myeloperoxidase	0	5	0	5
Cytochrome P450 1A2	0	5	1	6
Cyclin-dependent kinase 1	0	1	0	1
Beta-glucuronidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	3
ATP-dependent translocase ABCB1	0	12	1	16
Neutrophil elastase	0	2	0	2
Integrin alpha-IIb	6	0	0	6
Ornithine decarboxylase	1	0	0	2
Poly [ADP-ribose] polymerase 1	0	2	0	2
Replicase polyprotein 1a	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Replicase polyprotein 1ab	0	8	2	10
Replicase polyprotein 1ab	0	7	2	9
Androgen receptor	0	3	2	6
Sialidase	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	0	2
Aromatase	0	4	0	4
Cystic fibrosis transmembrane conductance regulator	0	1	1	2
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Pyruvate kinase PKM	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Urease subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	4	0	4
G2/mitotic-specific cyclin-B	0	1	0	1
Mucin-1	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	11	2	13
Casein kinase II subunit alpha'	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	6
Acetylcholinesterase	0	9	0	9
Carbonic anhydrase 4	0	6	0	10
Amine oxidase [flavin-containing] B	0	6	0	6
Dipeptidyl peptidase 4	0	2	0	2
Proteasome subunit beta type-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	12	3	15
Substance-P receptor	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	1
Prostaglandin G/H synthase 2	0	4	0	4
Mu-type opioid receptor	0	9	5	17
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Acetylcholinesterase	0	1	0	3
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Delta-type opioid receptor	0	9	3	15
Kappa-type opioid receptor	0	8	2	14
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Xanthine dehydrogenase/oxidase	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	11	2	13
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Estrogen receptor	0	0	1	1
Nuclear receptor ROR-gamma	12	1	1	14
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Beta-secretase 1	0	2	0	3
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	11	0	11
Lactoperoxidase	0	1	0	2
Xanthine dehydrogenase/oxidase	0	1	0	1
MO15-related protein kinase Pfmrk	0	1	0	1
Inositol monophosphatase 1	13	0	0	13
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Cyclin homolog	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	11	2	13
Mitogen-activated protein kinase 14	0	1	0	1
Cytochrome P450 1B1	0	4	0	4
Carbonic anhydrase 3	0	1	0	1
Substance-K receptor	0	2	0	2
Reverse transcriptase/RNaseH	0	6	2	17
Integrase	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	11	0	11
Casein kinase II subunit alpha 3	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Inositol hexakisphosphate kinase 1	23	0	0	23
Estrogen receptor beta	0	2	1	3
Enoyl-acyl-carrier protein reductase	0	3	0	3
Aurora kinase B	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	11	0	11
Myocilin	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
Prenyltransferase homolog	0	0	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
Carboxylic ester hydrolase	0	1	0	2
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Estrogen receptor beta	0	0	1	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	11	0	11
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
Sialidase-2	0	1	0	1
cytochrome P450 2C9, partial	23	0	0	23
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
5-hydroxytryptamine receptor 3E	0	3	0	3
SMAD family member 2	18	0	0	18
Fumarate hydratase	8	0	0	8
SMAD family member 3	18	0	0	18
polyprotein	8	0	0	8
lysosomal alpha-glucosidase preproprotein	5	0	0	5
mu-type opioid receptor isoform MOR-1	0	0	2	2
potassium voltage-gated channel subfamily H member 2 isoform d	15	0	0	15
transcriptional regulator ERG isoform 3	6	0	0	6
histone acetyltransferase KAT2A isoform 1	19	0	0	19
5-hydroxytryptamine receptor 2A	0	0	2	2
Solute carrier family 22 member 2	0	5	0	7
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	3	0	3
Cytochrome P450 3A4	0	15	1	16
5-hydroxytryptamine receptor 1A	0	6	6	12
Neuronal acetylcholine receptor subunit alpha-4	3	2	0	5
Neuronal acetylcholine receptor subunit beta-2	3	2	0	5
Alpha-1B adrenergic receptor	0	13	0	13
D	0	7	0	7
D(4) dopamine receptor	0	11	1	12
Alpha-1D adrenergic receptor	0	9	0	9
D(4) dopamine receptor	0	5	0	5
Histamine H1 receptor	0	3	2	5
5-hydroxytryptamine receptor 7	0	6	0	6
Alpha-1A adrenergic receptor	0	5	0	5
Alpha-1B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	5	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Spike glycoprotein	25	0	2	27
D(2) dopamine receptor	0	16	3	19
5-hydroxytryptamine receptor 3D	0	3	0	3
Multidrug and toxin extrusion protein 2	0	3	0	3
5-hydroxytryptamine receptor 3C	0	3	0	3
Multidrug and toxin extrusion protein 1	0	6	0	6
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	11	0	0	11
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
glp-1 receptor, partial	16	0	0	16
TAR DNA-binding protein 43	13	0	0	13
Guanylate cyclase soluble subunit beta-2	0	0	1	1
Guanylate cyclase soluble subunit alpha-2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Membrane primary amine oxidase	0	0	0	1
Trypsin-1	0	1	0	1
Phenylethanolamine N-methyltransferase	0	1	0	2
Alpha-2B adrenergic receptor	0	5	0	5
Amiloride-sensitive amine oxidase [copper-containing]	0	0	0	1
Alpha-2C adrenergic receptor	0	5	0	5
Alpha-2A adrenergic receptor	0	5	0	5
Amine oxidase [flavin-containing] B	0	2	0	3
Steroid C26-monooxygenase	0	0	3	3
Cytochrome P450 130	0	0	1	1
Cytochrome P450 130	0	0	1	1
Membrane primary amine oxidase	0	0	0	1
Lysyl oxidase homolog 2	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
galanin receptor type 3	0	1	0	1
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	3	0	3
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	5	3	8
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
DNA polymerase beta	4	0	0	4
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	5	0	5
Cholinesterase	0	3	0	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	5	0	5
Adenosine receptor A1	0	4	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	4	1	6
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Adenosine receptor A2a	0	3	0	7
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	2
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	1
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	5
Cannabinoid receptor 1	0	4	0	4
Prostaglandin G/H synthase 1	0	3	0	3
Cannabinoid receptor 2	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	3	3	7
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Metallo-beta-lactamase type 2	0	1	1	2
Prothrombin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	7	1	8
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	4	0	4
Solute carrier family 15 member 1	0	3	0	3
Beta-lactamase TEM	0	2	0	2
Mu-type opioid receptor	0	6	2	9
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	2	4
Beta-lactamase class B VIM-2	0	1	1	2
Chain A, Beta-lactamase	12	0	0	12
Vpr	4	0	0	4
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 2 subunit alpha	0	7	0	7
Sodium channel protein type 3 subunit alpha	0	4	0	4
UDP-glucuronosyltransferase 2B7	0	1	0	2
Cytochrome P450 2B6	0	0	1	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
5-hydroxytryptamine receptor 1D	0	1	0	3
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Carbonic anhydrase 4	0	3	0	5
interferon gamma precursor	0	0	0	1
Alpha-synuclein	9	4	0	13
caspase 7, apoptosis-related cysteine protease	11	0	0	11
caspase-3	11	0	0	11
thyrotropin-releasing hormone receptor	7	0	0	7
vitamin D3 receptor isoform VDRA	20	0	0	20
Caspase-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	4
Translocator protein	0	2	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
acid sphingomyelinase	2	0	0	2
PAX8	0	0	0	1
PINK1	4	0	0	4
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	2	0	2
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
huntingtin isoform 2	7	0	0	7
importin subunit beta-1 isoform 1	7	0	0	7
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	6	0	0	6
protein AF-9 isoform a	0	0	0	1
snurportin-1	7	0	0	7
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	7	0	0	7
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	3	0	4
Glutathione reductase, mitochondrial	0	1	0	2
72 kDa type IV collagenase	0	3	0	3
Matrix metalloproteinase-9	0	1	0	1
Trypanothione reductase	0	1	0	1
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Spermine oxidase	0	1	0	1
Carbonic anhydrase	0	5	0	7
Carbonic anhydrase 15	0	4	0	6
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
shiga toxin 1 variant A subunit	1	0	0	1
shiga toxin 1 B subunit	1	0	0	1
Cell division protein FtsZ	0	1	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Sodium-dependent noradrenaline transporter	0	3	0	3
Tryptophan 5-hydroxylase 1	0	3	0	3
Aldo-keto reductase family 1 member B1	0	3	0	3
Aromatase	0	1	1	2
Sodium-dependent dopamine transporter	0	12	0	12
Sigma intracellular receptor 2	0	4	0	4
Sodium-dependent serotonin transporter	0	3	0	3
Sodium-dependent dopamine transporter	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	5	0	5
Transporter	0	12	0	12
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Translocator protein	0	2	0	2
Translocator protein	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	3
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	3
Glutamate receptor ionotropic, NMDA 2B	0	2	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	3
Glutamate receptor ionotropic, NMDA 3B	0	1	0	3
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	3
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
Rap guanine nucleotide exchange factor 3	5	0	0	5
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
GALC protein	7	0	0	7
Sex hormone-binding globulin	0	0	2	2
Beta-glucuronidase	0	1	0	1
Corticosteroid-binding globulin	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
G-protein coupled bile acid receptor 1	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier family 22 member 3	0	1	0	1
Albumin	0	0	3	4
Prostaglandin G/H synthase 1	0	1	0	1
Solute carrier family 22 member 1	0	6	0	9
Histamine H3 receptor	0	1	0	1
Solute carrier family 22 member 2	0	5	0	7
Solute carrier family 22 member 4	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
polyunsaturated fatty acid lipoxygenase ALOX12	4	0	0	4
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Epidermal growth factor receptor	0	3	0	3
Glutamate receptor 1	2	0	0	2
Glutamate receptor 3	2	0	0	2
Glutamate receptor 4	2	0	0	2
Caspase-7	2	0	0	2
Spike glycoprotein	0	0	2	2
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	1	2	3
Chain A, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
Prothrombin	0	2	0	2
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	3	0	3
Kappa-type opioid receptor	0	7	0	8
Cannabinoid receptor 1	0	3	0	3
Microsomal triglyceride transfer protein large subunit	0	2	0	2
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120	0	1	0	1
Protease	0	2	0	3
Fructose-1,6-bisphosphatase 1	0	0	0	2
Reverse transcriptase	0	2	2	4
Cholesterol 24-hydroxylase	0	0	1	1
Type-2 angiotensin II receptor	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	1	0	1
Type-1 angiotensin II receptor	0	0	0	1
Cytochrome P450 1A1	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	2	3
Delta-type opioid receptor	0	6	1	8
Delta-type opioid receptor	0	7	1	8
Mu-type opioid receptor	0	10	2	12
Kappa-type opioid receptor	0	4	1	5
Mu-type opioid receptor	0	3	2	6
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	6
Chymotrypsinogen A	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Heme oxygenase 1	0	2	0	2
ATP-dependent translocase ABCB1	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	1	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Heme oxygenase 2	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	2	0	2
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	2	2
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	2	2
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	1	1
heat shock protein 90, putative	0	0	0	5
likely tRNA 2'-phosphotransferase	0	1	0	1
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
ras-related protein Rab-9A	5	0	0	5
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2D6	0	11	1	13
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Cytochrome P450 2C19	0	9	1	11
Gastrin/cholecystokinin type B receptor	0	1	0	1
Transporter	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	1	0	0	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	1	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
hypothetical protein, conserved	3	0	0	3
fructose-bisphosphate aldolase A	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
Carbonic anhydrase 12	0	3	0	6
Pancreatic triacylglycerol lipase	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Carbonic anhydrase 3	0	3	0	5
Matrilysin	0	1	0	1
L-selectin	0	1	0	1
P-selectin	0	1	0	1
E-selectin	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Carbonic anhydrase 6	0	4	0	7
Nitric oxide synthase, inducible	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	4	1	8
Carbonic anhydrase 7	0	3	0	6
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	2	0	2
Autoinducer 2-binding periplasmic protein LuxP	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Polypeptide N-acetylgalactosaminyltransferase 2	0	1	1	2
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Carbonic anhydrase 9	0	6	1	11
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Toll-like receptor 2	0	1	0	1
Carbonic anhydrase 14	0	2	0	5
Carbonic anhydrase 5B, mitochondrial	0	4	0	7
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	4	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	2	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	2
Macrophage migration inhibitory factor	0	3	0	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase	0	2	0	5
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	5
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	1	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	3	3	6
Histamine H3 receptor	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	2
Genome polyprotein	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	2	0	2
luciferase	2	0	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Dopamine beta-hydroxylase	0	1	0	1
Corticotropin-releasing factor receptor 1	0	1	0	1
Cystathionine beta-synthase	0	1	0	1
Glutathione reductase	0	1	0	1
5-lipoxygenase	0	1	0	1
Cysteine protease ATG4B	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	2	0	2
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	2
DNA gyrase subunit B	0	2	0	2
Cytochrome P450 2A6	0	2	1	3
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	3	0	4
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	1	0	0	1
D	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Androgen receptor	0	8	0	8
nonstructural protein 1	4	0	0	4
Progesterone receptor	0	2	1	3
Mineralocorticoid receptor	0	1	0	1
Androgen receptor	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Aldo-keto reductase family 1 member C2	0	2	0	2
Aldo-keto reductase family 1 member C1	0	2	0	2
ClpP	2	0	0	2
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Carboxylic ester hydrolase	0	1	0	1
Secreted chorismate mutase	0	1	0	1
Transient receptor potential cation channel subfamily M member 8	0	2	2	5
Transient receptor potential cation channel subfamily M member 8	0	0	1	1
serine/threonine-protein kinase PLK1	5	0	0	5
Metabotropic glutamate receptor 6	0	1	0	1
Acetylcholinesterase	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Beta-3 adrenergic receptor	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Substance-K receptor	0	6	0	7
Thromboxane-A synthase	0	1	0	1
Substance-P receptor	0	6	1	7
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	4	0	4
Melanocortin receptor 3	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Cholinesterase	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Calcium release-activated calcium channel protein 1	0	1	0	1
methionyl-tRNA synthetase, putative	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
D-amino-acid oxidase	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Histidine decarboxylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Kappa-type opioid receptor	0	2	2	4
Nociceptin receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Neuromedin-K receptor	0	0	2	2
Substance-K receptor	0	1	2	3
Neuromedin-K receptor	0	2	2	4
Substance-K receptor	0	2	0	2
Substance-K receptor	0	2	0	2
Chain B, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain B, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Reverse transcriptase/ribonuclease H	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Imidazoleglycerol-phosphate dehydratase	0	1	0	1
Ryanodine receptor 1	0	1	0	1
Exoribonuclease H	0	1	0	1
Cardiac ryanodine receptor 2	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	3	0	3
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
D(3) dopamine receptor	0	6	1	7
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Envelope glycoprotein	0	0	2	2
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
Chain A, CATHEPSIN D	0	1	0	1
Chain B, CATHEPSIN D	0	1	0	1
Chain A, PLASMEPSIN II	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Pepsin A	0	2	0	2
Cathepsin D	0	2	0	3
Cathepsin B	0	1	0	1
Pro-cathepsin H	0	1	0	1
Candidapepsin-2	0	1	0	1
Pepsin A-5	0	1	0	1
Gag-Pro polyprotein	0	1	0	1
Cathepsin E	0	1	0	1
Plasmepsin-1	0	1	0	1
Plasmepsin-2	0	1	0	1
Cathepsin D	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 9	0	1	0	1
Plasmepsin 4	0	1	0	1
Cysteine protease	0	1	0	1
Chymotrypsin-C	0	1	0	1
Protease	0	2	0	2
beta-2 adrenergic receptor	1	0	0	1
tumor necrosis factor	2	0	0	2
caspase-1 isoform alpha precursor	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
DNA polymerase III, partial	1	0	0	1
XBP1	0	1	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
D(1B) dopamine receptor	0	3	0	3
WD repeat-containing protein 48	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Pyridoxal kinase	0	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
Riboflavin-binding protein	0	1	1	2
Transient receptor potential cation channel subfamily M member 1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	2	0	2
Eyes absent homolog 2	0	1	0	1
Substance-P receptor	0	2	0	2
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
D(2) dopamine receptor	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Stromelysin-1	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Nrf2	1	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
toll-like receptor 9	0	1	0	1
caspase recruitment domain family, member 15	0	1	0	1
neurotensin receptor type 1	0	0	1	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
large T antigen	0	1	0	1
Beta lactamase (plasmid)	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-ACP reductase II	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (295)

Protein Targets (1,357)

Burning Mouth Syndrome

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (295)

Drugs Studied (209)

Protein Targets (1,357)