Conditions > Alveolalgia
Page last updated: 2024-09-28

Alveolalgia

A condition sometimes occurring after tooth extraction, particularly after traumatic extraction, resulting in a dry appearance of the exposed bone in the socket, due to disintegration or loss of the blood clot. It is basically a focal osteomyelitis without suppuration and is accompanied by severe pain (alveolalgia) and foul odor. (Dorland, 28th ed)

Synonyms(7)

Synonym
Periostitis, Alveolar
Alveolalgia
Osteitis, Alveolar
Alveolar Osteitis
Alveolar Periostitis
Alveolitis Sicca Dolorosa
Dry Socket

Research Excerpts

Overview

ExcerptReference
"Alveolar osteitis (dry socket) is the most common complication following the extraction of permanent teeth."( Metin, M; Sener, I; Tek, M, 2006)
"Alveolar osteitis (dry socket) is a complication of dental extractions and occurs more commonly in extractions involving mandibular molar teeth."( Daly, B; Jones, K; Newton, T; Sharif, MO; Worthington, HV, 2012)
"Alveolar osteitis is a very painful and distressing condition for a patient who has recently undergone a tooth extraction and has led dental professionals to search for preventive measures."( Teshome, A, 2017)
"Alveolar osteitis is a complication that can occur after tooth extraction, whereby exposed bone results in severe throbbing pain for the patient and can be prone to infection."( Bender, L; Boostrom, HM; Celiksoy, V; Cowpe, J; Heard, CM; Sloan, A; Varricchio, C; Zuanon, M, 2020)
"Alveolar osteitis is one of the most common post-op- erative complications in which antibiotic use is controversial."( Buonavoglia, A; Cordisco, M; Corrente, M; Prati, C; Trotta, A; Zamparini, F, 2022)
"Alveolar osteitis (dry socket) is a complication of dental extractions more often involving mandibular molar teeth."( Beattie, A; Daly, BJ; Jones, K; Sharif, MO; Worthington, HV, 2022)

Treatment

ExcerptReference
"To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model."( Cardoso, CL; Carvalho, PS; Cestari, TM; Dionísio, TJ; Ferreira Júnior, O; Garlet, GP, 2011)
"PRGF predictably treated alveolar osteitis after tooth extraction compared with the conventional standard treatment of Alvogyl, which has been used for many years."( Cerajewska, TL; Claydon, NCA; Davies, M; King, EM; Locke, M; West, NX, 2018)
"Fifty-four patients diagnosed with alveolar osteitis were divided into three groups for the treatment protocol."( Çebi, AT, 2020)
"In the treatment of alveolar osteitis, irrigation with antibiotics following curettage was found effective for pain relief and alveolar mucosa healing."( Çebi, AT, 2020)

Research

Studies (283)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990120 (42.40)23.3326
1990's35 (12.37)12.5806
2000's45 (15.90)18.1394
2010's59 (20.85)28.8240
2020's24 (8.48)9.53
DrugIndicatedRelationship StrengthStudiesTrials
allantoin0low10
choline0medium41
guaiacol0low20
aminocaproic acid0medium11
lactic acid0medium51
dimethyl sulfoxide0medium21
glycerol0low20
hydrogen carbonate0low20
4-aminobenzoic acid0low10
taurine0medium21
thiamine0low10
acetaminophen0medium44
alendronate0low10
antipyrine0low10
aspirin0medium297
benzocaine0low10
caffeine0medium11
camphor, (+-)-isomer0low10
carbamazepine0low10
cetylpyridinium0medium11
clioquinol0low10
dibucaine0medium21
diclofenac0medium11
glutaral0low10
hexachlorophene0low10
ibuprofen0medium22
lidocaine0medium135
mefenamic acid0low10
mepivacaine0low10
methadone0low10
metronidazole0medium2210
pamidronate0low20
phenacetin0low10
4-aminobenzoic acid0medium85
prilocaine0medium32
procaine0low10
sodium iodide0low10
tetracaine0medium21
tranexamic acid0medium41
prednisolone0low10
sorbitol0low10
prednisone0low10
adrenochrome0low10
penicillin g0medium21
chloramphenicol0medium11
oxacillin0low10
ampicillin0low10
mannitol0low10
methyl iodide0low10
iodoform0low40
acrylic acid0low10
methylprednisolone0medium11
penicillin v0medium21
thymol0low20
aminacrine0low10
tolonium chloride0low10
propylparaben0medium164
boric acid0low20
framycetin0medium52
betamethasone0medium11
azomycin0low10
trimecaine0low10
erythromycin0medium21
zinc oxide0low20
bisphenol a-glycidyl methacrylate0low10
flumethasone0low10
streptomycin0low10
enbucrilate0low10
samarium0low10
silver0low30
titanium0low10
tricalcium phosphate0low20
ozone0medium21
trolamine salicylate0low20
fluorides0low10
taurolidine0medium21
iodine0low10
cephapirin0low10
carticaine0low20
amoxicillin0medium138
ticarcillin0low10
propiconazole0low10
octenidine0medium21
4-aminomethylbenzoic acid0low10
cephalosporin c0medium31
iprazochrome0low10
lenampicillin0low10
zoledronic acid0low20
n-methylscopolamine0low10
acemannan0medium22
htr composite0low10
methotrexate0low10
povidone-iodine0medium43
fibrin0medium31
inositol 3-phosphate0medium31
betadex0low10
pectins0low10
clindamycin0medium1410
fosfomycin0low10
zithromax0medium21
sodium bicarbonate0low20
dipyrone0low10
fusidic acid0low10
lincomycin0medium42
aspirin, 4-hydroxybenzoic acid propyl ester, drug combination0low40
sodium dodecyl sulfate0low10
chloramine-t0low10
clavulanic acid0low10
codeine0medium22
phosphorus0low10
cefatrizine0medium11
chlorhexidine0medium5327
amoxicillin-potassium clavulanate combination0medium74
cefditoren0low10
rifamycins0low10
jaw0low40
azidocillin0medium11
cellulose0low20
chitosan0medium54
mannans0medium22
methylcellulose0low10
ascorbic acid0low20
tetracycline0medium153
chlortetracycline0medium32
oxytetracycline, anhydrous0low40
minocycline0low10
salicylates0medium62
choline salicylate0low10
gluma0low10
nebacetin0low10
vitamin b 120low10
lactoferrin0medium11
exudates0low10
folic acid0low10
rifampin0low10
formocresol0low10

Protein Targets (983)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Genome polyprotein 0011
USP1 protein, partial170017
AR protein430043
thyroid stimulating hormone receptor180018
glucocorticoid receptor [Homo sapiens]360036
retinoic acid nuclear receptor alpha variant 1360036
estrogen nuclear receptor alpha500050
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a250025
Histone H2A.x130013
chromobox protein homolog 1190019
transcriptional regulator ERG isoform 36006
geminin340034
Polyphenol oxidase 20303
Cellular tumor antigen p53250025
Thiopurine S-methyltransferase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Cytochrome P450 1B10202
Dihydropteroate synthase 0011
Chain A, Toluene-4-monooxygenase system protein A0101
Trypsin-10101
RAR-related orphan receptor gamma290029
ATAD5 protein, partial120012
GLS protein100010
Microtubule-associated protein tau110011
Smad38008
aldehyde dehydrogenase 1 family, member A1220022
nuclear receptor subfamily 1, group I, member 3180018
progesterone receptor190019
EWS/FLI fusion protein130013
retinoid X nuclear receptor alpha290029
estrogen-related nuclear receptor alpha360036
peroxisome proliferator activated receptor gamma210021
aryl hydrocarbon receptor180018
thyroid hormone receptor beta isoform 2290029
peripheral myelin protein 22100010
cytochrome P450 3A4 isoform 1110011
Gamma-aminobutyric acid receptor subunit pi110011
ATP-binding cassette sub-family C member 3026026
Multidrug resistance-associated protein 4026028
Solute carrier family 22 member 60505
Carbonic anhydrase 120304
UDP-glucuronosyltransferase 1A90103
Bile salt export pump011011
Voltage-dependent calcium channel gamma-2 subunit170017
Bile salt export pump038038
Cytochrome P450 2B10102
Cytochrome P450 1A10001
Carbonic anhydrase 1016017
Carbonic anhydrase 2016118
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20204
Prostaglandin G/H synthase 10606
Carbonic anhydrase 30203
Cytochrome P450 3A40707
Cytochrome P450 2D60303
Cytochrome P450 2C9 013014
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1110011
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta110011
Gamma-aminobutyric acid receptor subunit gamma-2110011
UDP-glucuronosyltransferase 1-60304
Glutamate receptor 2170017
Gamma-aminobutyric acid receptor subunit alpha-5110011
Gamma-aminobutyric acid receptor subunit alpha-3110011
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0406
Carbonic anhydrase 40708
Prostaglandin G/H synthase 10708
Carbonic anhydrase 60405
Gamma-aminobutyric acid receptor subunit gamma-1110011
Gamma-aminobutyric acid receptor subunit alpha-2110011
Gamma-aminobutyric acid receptor subunit alpha-4110011
Gamma-aminobutyric acid receptor subunit gamma-3110011
Gamma-aminobutyric acid receptor subunit alpha-6110011
Carbonic anhydrase 5A, mitochondrial0304
Prostaglandin G/H synthase 209112
Carbonic anhydrase 70203
Nuclear receptor ROR-gamma140014
Cytochrome P450 2J2011011
Gamma-aminobutyric acid receptor subunit alpha-1112013
Gamma-aminobutyric acid receptor subunit beta-3110011
Gamma-aminobutyric acid receptor subunit beta-2110011
Carbonic anhydrase 90607
GABA theta subunit110011
Canalicular multispecific organic anion transporter 1025025
Carbonic anhydrase 150606
Carbonic anhydrase 130102
Gamma-aminobutyric acid receptor subunit epsilon110011
Carbonic anhydrase 140304
Carbonic anhydrase 5B, mitochondrial0303
toxin B0001
euchromatic histone-lysine N-methyltransferase 2250025
lamin isoform A-delta10300030
Choline O-acetyltransferase 0203
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Chain A, ATP-DEPENDENT DNA HELICASE Q16006
phosphopantetheinyl transferase9009
TDP1 protein280028
vitamin D3 receptor isoform VDRA160016
thyroid hormone receptor beta isoform a170017
DNA polymerase kappa isoform 1110011
histone acetyltransferase KAT2A isoform 1130013
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0405
Farnesyl pyrophosphate synthase0606
Acetylcholinesterase0505
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0404
Farnesyl pyrophosphate synthase 0202
RGS121001
GLI family zinc finger 3360036
estrogen receptor 2 (ER beta)180018
cytochrome P450 family 3 subfamily A polypeptide 4240024
Alpha-synuclein7209
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, 2-oxoglutarate Oxygenase110011
Chain A, Ferritin light chain6006
67.9K protein110011
alpha-galactosidase4004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1100010
nuclear receptor ROR-gamma isoform 1120012
survival motor neuron protein isoform d7007
caspase-1 isoform alpha precursor2002
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0303
Trypanothione reductase0202
Caspase-73003
Chain A, PLASMINOGEN0022
Chain A, PLASMINOGEN0022
Chain A, Apolipoprotein0011
15-lipoxygenase, partial8008
regulator of G-protein signaling 45005
nonstructural protein 17007
arylsulfatase A5005
D(1A) dopamine receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Rap guanine nucleotide exchange factor 35005
Plasminogen0426
Proton-coupled amino acid transporter 10202
Chain A, Beta-lactamase100010
Beta-lactamase 0104
Beta-lactamase 0104
Beta-lactamase 0003
Beta-lactamase 0104
apical membrane antigen 1, AMA14004
Beta-lactamase 0002
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)9009
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
Beta-lactamase SHV-10104
Beta-lactamase SHV-10205
Beta-lactamase0103
Kappa-type opioid receptor0003
Solute carrier family 15 member 10707
Solute carrier family 15 member 10202
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20404
Beta-lactamase 0104
Beta-lactamase 0104
Solute carrier family 15 member 20505
Beta-lactamase 0104
Beta-lactamase 0002
Chain A, Mutant Al2 6e7p9g0011
Chain A, Cruzipain8008
Beta-lactamase 0002
acid sphingomyelinase5005
farnesoid X nuclear receptor220022
Beta-lactamase 0103
Beta-lactamase 0003
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0003
Metallo-beta-lactamase0003
Beta-lactamase 0103
DNA polymerase beta6006
60 kDa heat shock protein, mitochondrial0404
Beta-lactamase OXA-70003
Spike glycoprotein110011
10 kDa heat shock protein, mitochondrial0404
Angiopoietin-1 receptor0011
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0102
Thiosulfate sulfurtransferase0404
Metallo-beta-lactamase VIM-130002
Efflux transporter 0002
Beta-lactamase 0001
Beta-lactamase Toho-10002
Beta-lactamase 0002
Class D beta-lactamase0104
60 kDa chaperonin 0404
Metallo-beta-lactamase0001
Beta-lactamase 0102
Beta-lactamase 0002
10 kDa chaperonin 0404
Metallo-b-lactamase 0003
Carbapenem-hydrolyzing beta-lactamase KPC0204
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0003
Beta-lactamase VIM-1 0002
ATP-dependent phosphofructokinase8008
peroxisome proliferator-activated receptor delta190019
nuclear factor erythroid 2-related factor 2 isoform 2140014
nuclear factor erythroid 2-related factor 2 isoform 1340034
Nicotinate phosphoribosyltransferase0303
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase120012
thioredoxin glutathione reductase6006
vitamin D (1,25- dihydroxyvitamin D3) receptor240024
IDH1180018
lethal(3)malignant brain tumor-like protein 1 isoform I2002
lethal factor (plasmid)9009
Pancreatic alpha-amylase0202
Albumin0202
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0213
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0022
ras protein, partial0022
interleukin 88008
thioredoxin reductase7007
hypothetical protein, conserved3003
cytochrome P450 2D6130013
glucocerebrosidase4004
Rac1 protein0022
cell division cycle 42 (GTP binding protein, 25kDa), partial0022
Bloom syndrome protein isoform 14004
muscarinic acetylcholine receptor M16006
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0404
Prostaglandin G/H synthase 2 0303
Epidermal growth factor receptor0404
Fatty acid-binding protein, liver0404
Integrin beta-36107
Myeloperoxidase0202
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb6107
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A11507
Adenosine receptor A2a0406
Substance-P receptor0202
Urotensin-2 receptor0202
4-aminobutyrate aminotransferase, mitochondrial0202
Ras-related protein Rab-2A0022
Prostaglandin G/H synthase 20606
Rho-associated protein kinase 20101
Solute carrier family 22 member 200404
Solute carrier family 22 member 60404
Sigma non-opioid intracellular receptor 10213
Sigma non-opioid intracellular receptor 10011
glp-1 receptor, partial100010
G110011
thyroid stimulating hormone receptor160016
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 110011
TAR DNA-binding protein 43110011
Inositol hexakisphosphate kinase 1110011
ATPase family AAA domain-containing protein 5140014
Ataxin-2140014
cytochrome P450 2C9, partial110011
Chain A, D-MALTODEXTRIN BINDING PROTEIN0011
Chain A, Limit Dextrinase0011
Chain A, Solute-binding protein0011
Chain A, Solute-binding protein0011
Chain B, SusD0011
Chain A, SusD0011
Chain A, SusD0011
Chain A, Alpha-hemolysin0011
Chain B, Alpha-hemolysin0011
Chain C, Alpha-hemolysin0011
Chain D, Alpha-hemolysin0011
Chain E, Alpha-hemolysin0011
Chain F, Alpha-hemolysin0011
Chain G, Alpha-hemolysin0011
activating transcription factor 6150015
potassium voltage-gated channel subfamily H member 2 isoform d7007
pregnane X receptor9009
pregnane X nuclear receptor290029
nuclear receptor subfamily 1, group I, member 26006
galanin receptor type 30101
Glucocorticoid receptor010217
Glycine receptor subunit alpha-1010010
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
ORF730011
hypoxia-inducible factor 1 alpha subunit140014
SMAD family member 28008
SMAD family member 38008
TSHR protein2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
v-jun sarcoma virus 17 oncogene homolog (avian)200020
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
heat shock protein beta-1100010
Beta-lactamase0203
Beta-lactamase0303
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
atrial natriuretic peptide receptor 1 precursor1001
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0202
Adenosine receptor A30707
Replicase polyprotein 1ab0314
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2a0618
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0102
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Guanine deaminase0101
mitogen-activated protein kinase 17007
Vpr3003
Albumin0022
Major prion protein0011
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
UDP-glucuronosyltransferase 2B70206
Cytochrome P450 2B60325
Sodium channel protein type 4 subunit alpha0304
Potassium voltage-gated channel subfamily H member 20606
Sodium channel protein type 9 subunit alpha0505
Frizzled-80011
P2X purinoceptor 40101
Luciferase140014
Chain A, Carbonic anhydrase II0101
Carbonic anhydrase 0001
Carbonic anhydrase 0303
PPM1D protein4004
caspase 7, apoptosis-related cysteine protease3003
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
caspase-33003
thyrotropin-releasing hormone receptor2002
Caspase-72002
interferon gamma precursor0002
prostaglandin E2 receptor EP2 subtype0001
caspase-32002
Prostaglandin E synthase0101
Histone deacetylase 30202
3-phosphoinositide-dependent protein kinase 10101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Cytochrome c oxidase subunit 10101
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20202
Procathepsin L0101
Aldo-keto reductase family 1 member B10404
Neuronal acetylcholine receptor subunit alpha-43205
Polyunsaturated fatty acid 5-lipoxygenase0101
Quinolone resistance protein NorA0101
Neuronal acetylcholine receptor subunit beta-23205
Beta-3 adrenergic receptor0202
Alpha-1B adrenergic receptor0718
Calpain-2 catalytic subunit0101
5-hydroxytryptamine receptor 1A0101
D(1A) dopamine receptor0202
Prostaglandin G/H synthase 10202
Sodium-dependent noradrenaline transporter 0415
Cruzipain0101
Sodium/hydrogen exchanger 10101
Indoleamine 2,3-dioxygenase 10101
Sodium-dependent serotonin transporter0606
Sodium-dependent serotonin transporter0011
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0404
Bifunctional epoxide hydrolase 20202
Prostaglandin G/H synthase 2 0304
Carbonic anhydrase0606
Alpha-1A adrenergic receptor0718
Carbonic anhydrase0101
Histone deacetylase 40202
D(2) dopamine receptor0101
Carbonic anhydrase 0101
Mu-type opioid receptor0303
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Sodium-dependent dopamine transporter 0404
Prostaglandin G/H synthase 20303
Histone deacetylase 10202
Mitogen-activated protein kinase 140202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Sigma intracellular receptor 20101
Delta carbonic anhydrase0101
Prostaglandin G/H synthase 1 0304
Carbonic anhydrase 0101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 130101
Cyclooxygenase-2 0101
Histone deacetylase 70202
Rap guanine nucleotide exchange factor 43003
Histone deacetylase 20202
Carbonic anhydrase 40303
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
P2Y purinoceptor 120202
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
flap endonuclease 18008
streptokinase A precursor0066
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60516
30S ribosomal protein S70516
50S ribosomal protein L150516
50S ribosomal protein L100516
50S ribosomal protein L110516
50S ribosomal protein L7/L120516
50S ribosomal protein L190516
50S ribosomal protein L10516
50S ribosomal protein L200516
50S ribosomal protein L270516
50S ribosomal protein L280516
50S ribosomal protein L290516
50S ribosomal protein L310516
50S ribosomal protein L31 type B0516
50S ribosomal protein L320516
50S ribosomal protein L330516
50S ribosomal protein L340516
50S ribosomal protein L350516
50S ribosomal protein L360516
30S ribosomal protein S100516
30S ribosomal protein S110516
30S ribosomal protein S120516
30S ribosomal protein S130516
30S ribosomal protein S160516
30S ribosomal protein S180516
30S ribosomal protein S190516
30S ribosomal protein S200516
30S ribosomal protein S20516
30S ribosomal protein S30516
30S ribosomal protein S40516
30S ribosomal protein S50516
30S ribosomal protein S80516
30S ribosomal protein S90516
50S ribosomal protein L130516
50S ribosomal protein L140516
50S ribosomal protein L160516
50S ribosomal protein L230516
30S ribosomal protein S150516
50S ribosomal protein L170516
50S ribosomal protein L210516
50S ribosomal protein L300516
50S ribosomal protein L60516
30S ribosomal protein S140516
30S ribosomal protein S170516
30S ribosomal protein S10516
50S ribosomal protein L180516
50S ribosomal protein L20516
50S ribosomal protein L30516
50S ribosomal protein L240516
50S ribosomal protein L40516
50S ribosomal protein L220516
50S ribosomal protein L50516
30S ribosomal protein S210516
50S ribosomal protein L250516
50S ribosomal protein L36 20516
Methionine--tRNA ligase, mitochondrial0011
Chain A, JmjC domain-containing histone demethylation protein 3A4004
Chain A, BCL-2-RELATED PROTEIN A10011
PAX80002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
PINK12002
Parkin2002
heat shock protein 900022
calcineurin A1, putative0011
cytochrome P450 2D6 isoform 13003
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a6006
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor2002
perilipin-50101
perilipin-10101
huntingtin isoform 23003
importin subunit beta-1 isoform 15005
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 13003
protein AF-9 isoform a0001
snurportin-15005
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0305
Polyunsaturated fatty acid lipoxygenase ALOX15B7007
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0102
72 kDa type IV collagenase0303
Matrix metalloproteinase-90303
Histamine H2 receptor8008
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Multidrug and toxin extrusion protein 10606
Spermine oxidase0101
P2Y purinoceptor 120202
Protein-arginine deiminase type-4010010
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10203
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20203
Beta-lactamase 0101
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase0102
Neutrophil elastase0101
Beta-lactamase OXA-10101
Beta-lactamase TEM0305
Beta-lactamase0101
Beta-lactamase 0102
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0102
mu opioid receptor, partial0011
90-kda heat shock protein beta HSP90 beta, partial0202
Fumarate hydratase4004
polyprotein4004
bromodomain adjacent to zinc finger domain 2B5005
LAP40011
MEP20011
polyunsaturated fatty acid lipoxygenase ALOX124004
delta-type opioid receptor0112
kappa-type opioid receptor isoform 10101
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
heat shock protein HSP 90-alpha isoform 20205
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Amyloid-beta precursor protein0101
Botulinum neurotoxin type A 0101
Spike glycoprotein0101
Catechol O-methyltransferase0101
Alpha-1D adrenergic receptor0112
Disintegrin and metalloproteinase domain-containing protein 171001
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Beta-galactosidase0011
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
heat shock protein 90, putative0003
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Kappa-type opioid receptor0101
Mu-type opioid receptor0617
Delta-type opioid receptor0303
Kappa-type opioid receptor0505
Mu-type opioid receptor0101
Cytochrome P450 2D40101
Mas-related G-protein coupled receptor member X20033
lysosomal alpha-glucosidase preproprotein4004
Aldo-keto reductase family 1 member B100202
Transient receptor potential cation channel subfamily A member 10033
Dihydrofolate reductase0506
Transthyretin0013
Albumin0279
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0202
Aldo-keto reductase family 1 member B10303
UDP-glucuronosyltransferase 1A40202
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
UDP-glucuronosyltransferase 1A30002
UDP-glucuronosyltransferase 2B10 0202
Sodium- and chloride-dependent betaine transporter0101
Solute carrier family 22 member 60304
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Protein cereblon0202
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK13003
Motilin receptor0112
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10303
60 kDa chaperonin0202
Chitinase B0101
ATP-dependent translocase ABCB10202
Low molecular weight phosphotyrosine protein phosphatase0101
Lanosterol 14-alpha demethylase0303
Estrogen receptor0415
Sex hormone-binding globulin0011
Androgen receptor0808
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sulfotransferase 1A10214
Aldehyde oxidase0101
Nuclear receptor subfamily 1 group I member 3 0101
Estrogen receptor beta0314
ras-related protein Rab-9A1001
Chain A, Dihydrofolate reductase0011
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Thymidylate synthase0404
Thymidylate synthase0303
Dihydrofolate reductase0235
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
Estrogen receptor0022
Guanine nucleotide-binding protein G3003
Estrogen receptor beta0022
Canalicular multispecific organic anion transporter 10203
large T antigen0202
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
calpain II, partial0101
SUMO-10101
Mcl-10101
Valosin-containing protein0202
Estrogen receptor 10101
envelope glycoprotein0101
heat shock 70kDa protein 1A0101
galactokinase1001
NPC intracellular cholesterol transporter 1 precursor1001
tumor necrosis factor1001
neuropeptide Y receptor type 10011
neuropeptide Y receptor type 20011
small ubiquitin-related modifier 2 isoform b precursor0101
estrogen receptor beta isoform 10202
enteropeptidase precursor1001
fatty acid synthase0101
eukaryotic translation initiation factor 4 gamma 1 isoform 40202
heat shock cognate 71 kDa protein isoform 10101
eukaryotic translation initiation factor 4E isoform 10202
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
replicative DNA helicase0001
recombinase A0011
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
POsterior Segregation0011
heat shock cognate 71 kDa protein isoform 20101
5-hydroxytryptamine receptor 40404
Urokinase-type plasminogen activator0202
Tissue-type plasminogen activator0101
Receptor tyrosine-protein kinase erbB-20101
Plasminogen activator inhibitor 10101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Urokinase-type plasminogen activator0101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30224
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0202
Replicase polyprotein 1a0101
Muscarinic acetylcholine receptor M20202
Endoplasmic reticulum chaperone BiP0101
Macrophage migration inhibitory factor0202
Alpha-2C adrenergic receptor0202
Substance-K receptor0202
Thromboxane-A synthase 0101
Mitogen-activated protein kinase 3 0101
5-hydroxytryptamine receptor 2C0404
Mitogen-activated protein kinase 10101
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 2B0202
Inositol monophosphatase 11001
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
Zinc finger protein mex-50011
phosphoglycerate kinase2002
M1-family alanyl aminopeptidase0101
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
BZLF20101
NFKB1 protein, partial1001
muscleblind-like protein 1 isoform 15005
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40202
Polyunsaturated fatty acid 5-lipoxygenase0102
Caspase-10202
Aldo-keto reductase family 1 member C30303
Caspase-30101
Solute carrier organic anion transporter family member 1A10202
Caspase-40101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Fatty-acid amide hydrolase 10101
Solute carrier family 22 member 80204
Dehydrogenase/reductase SDR family member 90101
histone deacetylase 9 isoform 33003
Chymotrypsinogen A0101
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0202
Glutamate receptor ionotropic, NMDA 3B0101
Glutamate receptor ionotropic, NMDA 1 0202
Cholinesterase0202
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Glutamate receptor ionotropic, NMDA 3A0202
Potassium channel subfamily K member 30303
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 5 subunit alpha0202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0202
Serum paraoxonase/arylesterase 10202
glycogen synthase kinase-3 beta isoform 10022
Transient receptor potential cation channel subfamily M member 20101
Myc proto-oncogene protein0101
Aldo-keto reductase family 1 member C40101
Malate dehydrogenase, cytoplasmic0101
Aldo-keto reductase family 1 member C2 0202
Aldo-keto reductase family 1 member C10202
Peroxisome proliferator-activated receptor alpha2002
NACHT, LRR and PYD domains-containing protein 3 0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
D(2) dopamine receptor0101
D(4) dopamine receptor0101
D(3) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Aldehyde oxidase 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 81001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Kappa-type opioid receptor0101
Reduced folate transporter0202
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Solute carrier organic anion transporter family member 1B30204
Solute carrier family 22 member 110002
Nuclear receptor subfamily 1 group I member 20022
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0202
Protein mono-ADP-ribosyltransferase PARP150101
Muscarinic acetylcholine receptor M20314
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M10202
POU domain, class 2, transcription factor 10001
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor 0011
Muscarinic acetylcholine receptor 0101
Metabotropic glutamate receptor 50101
Snake venom metalloproteinase BaP10101
NAD(+) hydrolase SARM10202
Solute carrier family 22 member 80405
MecA 0101
WRN1001
microphthalmia-associated transcription factor isoform 90101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Cytochrome P450 1A2 0002
Arylacetamide deacetylase0103
Arylacetamide deacetylase0001
Arylacetamide deacetylase0001
luciferase0001
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1B10203
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Carbonic anhydrase 0202
GALC protein1001
Sodium- and chloride-dependent taurine transporter0101
5-hydroxytryptamine receptor 2A0202
cGMP-gated cation channel alpha-10011
Sodium channel protein type 7 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
Neutrophil collagenase0202
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Solute carrier family 22 member 70001
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain B, Odorant-binding Protein0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Secreted chorismate mutase0101
Heat sensitive channel TRPV30011
Transient receptor potential cation channel subfamily A member 10112
Transient receptor potential cation channel subfamily M member 80112
Microtubule-associated protein tau0202
twin arginine protein translocation system - TatA protein0001
Butyrophilin subfamily 3 member A10012
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]