tetracycline and Heart-Defects--Congenital

Topics: Bacteriological Techniques; Diagnosis; Embolism; Endocarditis, Bacterial; Erythromycin; Fever; Heart Defects, Congenital; Heart Valves; Humans; Lung Diseases; Penicillin Resistance; Penicillins; Pneumococcal Infections; Postoperative Complications; Prognosis; Sepsis; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline; Vancomycin

A retrospective study was done on patients admitted to the University of Michigan Hospital from 1962 to 1972 with a diagnosis of bacterial endocarditis. The findings in the group studied indicate that Streptococcus viridans was the predominant causative organism, males were affected three times as often as females, erythromycin was effective against organisms of oral origin, dental procedures were not definitely established as responsible for the onset of the disease in any of the cases, and rheumatic heart disease and congenital heart disease were the predominant, but not the only, predisposing factors.

Topics: Age Factors; Dental Care; Endocarditis, Bacterial; Erythromycin; Heart Defects, Congenital; Heroin Dependence; Humans; Microbial Sensitivity Tests; Mouth; Penicillins; Retrospective Studies; Rheumatic Heart Disease; Sex Factors; Streptococcus; Streptomycin; Tetracycline; Tooth

Topics: Adolescent; Adult; Animals; Antigens, Viral; Child; Digitalis Glycosides; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Male; Mice; Middle Aged; Myocarditis; Pregnancy; Tetracycline; Virus Diseases; Virus Replication; Viruses

Topics: Adolescent; Antibodies; Arrhythmias, Cardiac; Arteritis; Cardiovascular Diseases; Cerebrovascular Disorders; Child; Chlortetracycline; Coronary Disease; Geriatrics; Heart Defects, Congenital; Heart Diseases; Humans; Infant; Raynaud Disease; Rickettsia Infections; Rolitetracycline; Tetracycline; Thrombophlebitis; Thrombosis