Page last updated: 2024-08-05 12:18:55

crown amine

Crown compounds containing only nitrogen as coordinating atom.

ChEBI ID: 37411

Members (4)

MemberDefinitionRole
1,4,7-triazacyclononane1,4,7-triazonane
cyclam1,4,8,11-tetraazacyclotetradecane
cyclenAn azacycloalkane that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogen atoms.1,4,7,10-tetraazacyclododecane
plerixaforAn azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.plerixafor

Research

Studies (1,742)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19908 (0.46)18.7374
1990's44 (2.53)18.2507
2000's409 (23.48)29.6817
2010's1,099 (63.09)24.3611
2020's182 (10.45)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials113 (6.29%)5.53%
Reviews117 (6.51%)6.00%
Case Studies42 (2.34%)4.05%
Observational7 (0.39%)0.25%
Other1,517 (84.47%)84.16%