Page last updated: 2024-08-05 12:02:50

benzochromene

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ChEBI ID: 38920

Members (5)

MemberDefinitionRole
delta(9)-tetrahydrocannabinolic acidA diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.Delta(9)-tetrahydrocannabinolic acid
dronabinolA diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy.Delta(9)-tetrahydrocannabinol
jwh-133A dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist.JWH-133
phenazopyridinelapachenole
rubimaillinA benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme.rubimaillin

Research

Studies (8,047)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19902,252 (27.99)18.7374
1990's839 (10.43)18.2507
2000's1,484 (18.44)29.6817
2010's2,141 (26.61)24.3611
2020's1,331 (16.54)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials791 (9.12%)5.53%
Reviews837 (9.65%)6.00%
Case Studies204 (2.35%)4.05%
Observational47 (0.54%)0.25%
Other6,799 (78.35%)84.16%