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insecticide

Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.

ChEBI ID: 24852

Members (48)

MemberDefinitionClass
1-hexacosanolA very long-chain primary fatty alcohol that is hexacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.hexacosan-1-ol
1-naphthylisothiocyanate1-naphthyl isothiocyanate
4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrileA pyrrole resulting from the N-dealkylation of the ethoxymethyl group of chlorfenapyr. It is the active insecticide of the proinsecticide chlorfenapyr.tralopyril
4-dichlorobenzeneA dichlorobenzene carrying chloro groups at positions 1 and 4.1,4-dichlorobenzene
afidopyropenAn organic heterotetracyclic compound that is 1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromen-11-one which is substituted by methyl groups at positions 4, 6a, and 12b; hydroxy groups at positions 3, 6, and 9; and a cyclopropycarbonyloxymethyl group and a cyclopropylcarbonyloxy group at positions 17 and 18 respectively, and a pyridin-3-yl group at position 14 (the (3S,4R,4aR,6S,6aS,12R,12aS,12bS stereoisomer). It is an insecticide that is effective against sucking insects on fruit, vegetables and nuts.afidopyropen
allyl alcoholA propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.allyl alcohol
amitrazA tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5.amitraz
arsenic trioxideAn arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.diarsenic trioxide
bassianolideA cyclodepsipeptide consisting of a cyclic tetramer of the depsipeptide D-Hiv-N-methyl-L-leucine (where D-Hiv = D-alpha-hydroxyisovaleric acid). Found in the fungal species Beauveria bassiana and Verticillium lecanii, it has insecticidal properties and is used as a commercial biopesticide to control of insects of agricultural, veterinary and medical significance. For elucidation of the structure, see Suzuki et al., Tetrahedron Lett. 1977 v25, 2167-2170.bassianolide
bpmcA carbamate ester obtained by the formal condensation of 2-sec-butylphenol with methylcarbamic acid.fenobucarb
cevineA steroid consisting of cevane having an oxygen bridge between positions 4 and 9 and carrying seven additional hydroxy substituents.cevine
chlordeconeAn organochlorine compound with insecticidal activity.chlordecone
chlorpyrifosAn organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.chlorpyrifos
chlorpyrifos-methylAn organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.chlorpyrifos-methyl
cuminaldehydeA member of the class of benzaldehydes that is benzaldehyde substituted by an isopropyl group at position 4. It is a component of essential oils from Cumin and exhibits insecticidal activities.cuminaldehyde
diallyl trisulfideAn organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activitydiallyl trisulfide
dimethoateA monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.dimethoate
dodecanolA primary alcohol that is dodecane in which a hydrogen from one of the methyl groups is replaced by a hydroxy group. It is registered for use in apple and pear orchards as a Lepidopteran pheromone/sex attractant, used to disrupt the mating behaviour of certain moths whose larvae destroy crops.dodecan-1-ol
epoxyazadiradioneA limonoid that is azadiradione with an epoxy group across positions 14 and 15. Isolated from Azadirachta indica it exhibits insecticidal activitry against mosquitoes.epoxyazadiradione
ethionAn organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7).ethion
euonineA sesquiterpene alkaloid that has been isolated from Tripterygium wilfordii and exhibits immunosuppressive and insecticidal properties. It was found to be identical with euonine, previously isolated from Euonymous sieboldiana.wilformine
fenitrothionAn organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4.fenitrothion
fenoxycarbA carbamate ester that is the O-ethyl carbamate of 2-(4-phenoxyphenoxy)ethylamine.fenoxycarb
fenthionAn organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.fenthion
flonicamidA pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom.flonicamid
flupyradifuroneA tertiary amino compound that is ammonia in which the nitrogens have been replaced by (6-chloropyridin-3-yl)methyl, 2,2-difluoroethyl, and 5-oxo-2,5-dihydrofuran-3-yl groups, respectively. A nicotinic acetylcholine receptor (AChR) agonist, it is used as an insecticide to control sucking pests in a variety of crops.flupyradifurone
germacroneA germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities.(E,E)-germacrone
isoprothiolaneA malonate ester that is diisopropyl malonate in which the two methylene hydrogens at position 2 are replaced by a 1,3-dithiolan-2-ylidene group. An insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale.isoprothiolane
lead arsenateAn inorganic lead salt composed from lead(2+) and arsenate dianion. It was widely used in the United States in the 1950's as an insecticide to control pests in fruit orchards, specifically apples and cherries.lead arsenate
maysinA flavone C-glycoside that is luteolin attached to a disaccharide residue at position 6. It has been isolated from natural product Petrorhagia velutina and Zea mays and exhibits insecticidal and neuroprotective activities.maysin
methiocarbA carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid.methiocarb
methomylA carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.methomyl
methoxyfenozideA carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by 3-methoxy-2-methylbenzoyl, 3,5-dimethylbenzoyl, and tert-butyl groups respectively.methoxyfenozide
methyl formateA formate ester resulting from the formal condensation of formic acid with methanol. A low-boiling (31.5 degreeC) colourless, flammable liquid, it has been used as a fumigant and larvicide for tobacco and food crops.methyl formate
nereistoxinToxin isolated from marine segmented worm, Lumbriconereis heterodopa. It is also the active insecticide of the proinsecticide thiocyclam.nereistoxin
pirimicarbAn aminopyrimidine that is N,N,4,5-tetramethylpyrimidin-2-amine substituted by a (dimethylcarbamoyl)oxy group at position 4.pirimicarb
pirimiphos methylAn organic thiophosphate that is O,O-dimethyl O-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2.pirimiphos-methyl
prothiophosAn organic thiophosphate that is the 2,4-dichlorophenyl ester of O-ethyl S-propyl dithiophosphoric acid.prothiofos
pyrazophosA member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A profungicide (by hydrolysis of the thionophosphate group to afford the corresponding 2-hydroxypyrazolopyrimidine fungicide), it is used to control Erysiphe, Helminthosporium and Rhynchospium in cereals.pyrazophos
rediocide aA diterpenoid of the class of daphnane-type terpenes. It is isolated from Trigonostemon reidioides and has been shown to exhibit insecticidal activity.rediocide A
safroleA member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.safrole
sodium arseniteAn inoganic sodium salt with formula with formula NaAsO2.sodium arsenite
spiromesifenA butenolide that is but-2-en-4-olide bearing a 2,4,6-trimethylphenyl group at position 3, a 3,3-dimethylbutyryloxy group at position 4 and a spiro-fused cyclopentyl ring at position 5.spiromesifen
sulfluramidA sulfonamide obtained by the formal condensation of perfluorooctane-1-sulfonic acid with ethylamine.sulfluramid
teflubenzuronA N-acylurea that is N-carbamoyl-2,6-difluorobenzamide substituted by a 3,5-dichloro-2,4-difluorophenyl group at the terminal nitrogen atom.teflubenzuron
thallium sulfateA metal sulfate in which the counterion is thallium and the ratio of thallium to sulfate is 2:1. It is a rodenticide used to control rats, squirrels, mice, moles, prairie dogs, ants and cockroaches. It is no longer registered for pesticide use in the United States.thallium sulfate
trichlorfonA phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.trichlorfon
xanthoneThe parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.xanthone

Research

Studies (22,242)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19903,681 (16.55)18.7374
1990's2,537 (11.41)18.2507
2000's4,983 (22.40)29.6817
2010's7,282 (32.74)24.3611
2020's3,759 (16.90)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials339 (1.41%)5.53%
Reviews921 (3.83%)6.00%
Case Studies430 (1.79%)4.05%
Observational16 (0.07%)0.25%
Other22,361 (92.91%)84.16%

Protein Targets (188)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency22.583313
15-lipoxygenase, partialHomo sapiens (human)Potency28.207314
67.9K proteinVaccinia virusPotency11.220211
acetylcholinesteraseHomo sapiens (human)Potency38.7255439
activating transcription factor 6Homo sapiens (human)Potency38.580829
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency32.307018
alpha-galactosidaseHomo sapiens (human)Potency31.832622
Alpha-synucleinHomo sapiens (human)Potency10.000011
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency22.387211
AR proteinHomo sapiens (human)Potency34.138211100
aryl hydrocarbon receptorHomo sapiens (human)Potency34.5542340
ATAD5 protein, partialHomo sapiens (human)Potency0.231011
Ataxin-2Homo sapiens (human)Potency52.148613
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency52.148613
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency75.059412
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency46.421313
caspase-1 isoform alpha precursorHomo sapiens (human)Potency25.118911
caspase-3Cricetulus griseus (Chinese hamster)Potency65.781614
caspase-3Homo sapiens (human)Potency46.421313
Caspase-7Cricetulus griseus (Chinese hamster)Potency65.781614
Caspase-7Homo sapiens (human)Potency25.118911
Cellular tumor antigen p53Homo sapiens (human)Potency58.1651321
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency15.937022
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency28.183811
Chain A, Beta-lactamaseEscherichia coli K-12Potency39.810711
Chain A, CruzipainTrypanosoma cruziPotency31.622811
Chain A, Ferritin light chainEquus caballus (horse)Potency29.881612
Chain A, HADH2 proteinHomo sapiens (human)Potency22.527625
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency65.569415
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency27.194715
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency12.559411
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency56.797314
Chain B, HADH2 proteinHomo sapiens (human)Potency22.527625
chromobox protein homolog 1Homo sapiens (human)Potency89.716414
cytochrome P450 2C9, partialHomo sapiens (human)Potency3.890211
cytochrome P450 2D6Homo sapiens (human)Potency36.289812
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency18.2158218
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency20.979014
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency47.2385111
DNA polymerase kappa isoform 1Homo sapiens (human)Potency23.778112
estrogen nuclear receptor alphaHomo sapiens (human)Potency35.486012118
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency44.9971320
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency37.7998673
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency32.310512
farnesoid X nuclear receptorHomo sapiens (human)Potency36.0382414
GVesicular stomatitis virusPotency3.890211
GABA theta subunitRattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency18.215819
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency18.215819
gemininHomo sapiens (human)Potency12.415126
GLI family zinc finger 3Homo sapiens (human)Potency29.6464337
glp-1 receptor, partialHomo sapiens (human)Potency10.157812
glucocerebrosidaseHomo sapiens (human)Potency25.118911
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency41.8359518
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency41.3456112
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency0.410911
Guanine nucleotide-binding protein GHomo sapiens (human)Potency50.118711
heat shock protein beta-1Homo sapiens (human)Potency35.8314216
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency31.622812
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency23.507913
histone deacetylase 9 isoform 3Homo sapiens (human)Potency20.987423
Histone H2A.xCricetulus griseus (Chinese hamster)Potency93.1799215
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency3.890211
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency42.8626219
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency40.870812
IDH1Homo sapiens (human)Potency16.360111
importin subunit beta-1 isoform 1Homo sapiens (human)Potency44.768022
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency3.890212
Integrin alpha-IIbHomo sapiens (human)Potency0.251211
Integrin beta-3Homo sapiens (human)Potency0.251211
Interferon betaHomo sapiens (human)Potency3.890211
interleukin 8Homo sapiens (human)Potency74.978012
lamin isoform A-delta10Homo sapiens (human)Potency23.654513
lethal factor (plasmid)Bacillus anthracis str. A2012Potency21.747013
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency31.622811
LuciferasePhotinus pyralis (common eastern firefly)Potency54.1003215
Microtubule-associated protein tauHomo sapiens (human)Potency23.204727
mitogen-activated protein kinase 1Homo sapiens (human)Potency39.810711
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency0.316211
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency22.387211
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency38.2813452
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency14.581011
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency43.422813
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency41.5102217
Nuclear receptor ROR-gammaHomo sapiens (human)Potency17.840513
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency21.390526
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency29.0568366
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency100.000011
ParkinHomo sapiens (human)Potency39.810711
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency2.869511
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency45.8225524
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)Potency39.810711
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency35.6770512
phosphopantetheinyl transferaseBacillus subtilisPotency35.949916
PINK1Homo sapiens (human)Potency39.810711
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency31.099012
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency31.622811
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency25.425116
pregnane X nuclear receptorHomo sapiens (human)Potency33.2732230
pregnane X receptorRattus norvegicus (Norway rat)Potency54.122117
progesterone receptorHomo sapiens (human)Potency27.6634223
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency28.183811
Rap guanine nucleotide exchange factor 4Homo sapiens (human)Potency11.220211
RAR-related orphan receptor gammaMus musculus (house mouse)Potency25.2153230
regulator of G-protein signaling 4Homo sapiens (human)Potency50.118711
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency39.4288351
retinoid X nuclear receptor alphaHomo sapiens (human)Potency26.3046437
serine-protein kinase ATM isoform aHomo sapiens (human)Potency39.810711
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency28.307212
SMAD family member 2Homo sapiens (human)Potency25.284127
SMAD family member 3Homo sapiens (human)Potency25.284127
Smad3Homo sapiens (human)Potency25.483013
snurportin-1Homo sapiens (human)Potency44.768022
survival motor neuron protein isoform dHomo sapiens (human)Potency12.589311
TDP1 proteinHomo sapiens (human)Potency21.821826
thioredoxin reductaseRattus norvegicus (Norway rat)Potency50.050012
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency45.1050327
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency29.1126210
thyroid stimulating hormone receptorHomo sapiens (human)Potency27.5293644
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency26.347726
USP1 protein, partialHomo sapiens (human)Potency39.810711
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency33.2362227
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency34.7583520
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency48.7602110
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency41.3456112
VprHuman immunodeficiency virus 1Potency31.622811

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC5025.158011
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki16.009011
Acetylcholinesterase Drosophila melanogaster (fruit fly)IC501.830011
Adenosine receptor A3Homo sapiens (human)IC506.100011
Adenosine receptor A3Homo sapiens (human)Ki3.448011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC506.100011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)Ki3.448011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC506.100011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)Ki3.448011
Alpha-2A adrenergic receptorHomo sapiens (human)IC503.599412
Alpha-2A adrenergic receptorHomo sapiens (human)Ki1.349812
Alpha-2C adrenergic receptorHomo sapiens (human)IC5054.539011
Alpha-2C adrenergic receptorHomo sapiens (human)Ki7.924011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC507.968333
Androgen receptorRattus norvegicus (Norway rat)IC5018.767822
Androgen receptorRattus norvegicus (Norway rat)Ki17.009011
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
ATP-dependent translocase ABCB1Homo sapiens (human)IC5044.300011
Bile salt export pumpHomo sapiens (human)IC5064.500022
C-C chemokine receptor type 2Homo sapiens (human)IC506.699011
C-C chemokine receptor type 2Homo sapiens (human)Ki2.589011
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000011
Carboxylic ester hydrolase Musca domestica (house fly)IC509.510011
Carboxylic ester hydrolase Plutella xylostella (diamondback moth)IC501,355.500022
Cytochrome P450 1A2Homo sapiens (human)IC505.500012
Cytochrome P450 2A5Mus musculus (house mouse)IC501.000022
Cytochrome P450 2A6Homo sapiens (human)IC5016.991222
Cytochrome P450 2D6Homo sapiens (human)IC506.400011
D(1A) dopamine receptorHomo sapiens (human)IC5027.576011
D(1A) dopamine receptorHomo sapiens (human)Ki13.788011
Fatty acid synthaseGallus gallus (chicken)IC508.370022
Glucocorticoid receptorHomo sapiens (human)IC5015.403011
Glucocorticoid receptorHomo sapiens (human)Ki7.001011
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)IC5015.403011
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)Ki7.001011
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)IC5015.403011
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)Ki7.001011
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)IC5015.403011
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)Ki7.001011
Glycine receptor subunit betaRattus norvegicus (Norway rat)IC5015.403011
Glycine receptor subunit betaRattus norvegicus (Norway rat)Ki7.001011
Macrophage migration inhibitory factorHomo sapiens (human)IC507.620035
Macrophage migration inhibitory factor Plasmodium falciparum 3D7IC5010.000011
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011
Phosphoglycerate mutase 1Homo sapiens (human)IC500.500011
polyadenylate-binding protein 1Homo sapiens (human)IC5066.000022
Polyphenol oxidase 2Agaricus bisporusIC5075.000011
Sodium-dependent serotonin transporterHomo sapiens (human)IC5014.293011
Sodium-dependent serotonin transporterHomo sapiens (human)Ki7.593011
TyrosinaseHomo sapiens (human)IC5029.420022

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
20-hydroxy-ecdysone receptor Choristoneura fumiferana (eastern spruce budworm)EC500.280011
20-hydroxy-ecdysone receptor Spodoptera littoralis (African cotton leafworm)EC500.006011
Ecdysone receptorBombyx mori (domestic silkworm)EC500.036533
Ecdysone receptorDrosophila melanogaster (fruit fly)EC5016.595911
Estrogen receptorOvis aries (sheep)Kd0.490011
Estrogen receptor betaOvis aries (sheep)Kd0.490011
ORF73Human gammaherpesvirus 8EC5075.000011
Protein ultraspiracleDrosophila melanogaster (fruit fly)EC5016.595911
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)EC500.490011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Glutathione reductase, mitochondrialHomo sapiens (human)Km160.000011
heat shock protein 90, putativePlasmodium falciparum 3D7AC502.930011
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)AC502.685011
prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)Active Concentration20.000011