tetracycline has been researched along with Osteoradionecrosis* in 3 studies
3 other study(ies) available for tetracycline and Osteoradionecrosis
Article | Year |
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In vivo tetracycline labeling of bone: an intraoperative aid in the surgical therapy of osteoradionecrosis of the mandible.
In this technical approach, we demonstrate that preoperative tetracycline administration helps distinguish between viable and necrotic bone in osteoradionecrosis (ORN) during surgery by exciting tetracycline fluorescence by black light. The difficult aspect of the operative approach lies in the decision of the extent of the debridement in order to prevent an iatrogenic fracture or progression of ORN. With this technique, vital bone, in contrast to necrotic bone, showed detectable fluorescence. Therefore, tetracycline fluorescence labeling may be used in attempts to facilitate the intraoperative decision making in the surgical therapy of osteoradionecrosis. Topics: Cranial Irradiation; Fluorescent Dyes; Humans; Male; Mandibular Diseases; Middle Aged; Monitoring, Intraoperative; Osteoradionecrosis; Preoperative Care; Tetracycline; Ultraviolet Rays | 2006 |
Surgical management of osteoradionecrosis of the temporal bone.
The surgical management of osteoradionecrosis of the temporal bone has met with limited success because of the difficulty in accurate assessment of the viability of nonnecrotic bone intraoperatively. Failure to resect all nonviable bone results in recurrence of a necrotic focus. With the use of hyperbaric oxygen therapy to stabilize marginal bone and oral tetracycline to label viable bone preoperatively, removal of all nonviable bone can be accomplished. Postoperatively, a second course of hyperbaric therapy enhances wound healing, thus assuring a successful outcome. This article details a successful systematic approach that was developed to resect a necrotic focus in the temporal bone of a 10-year-old boy who had undergone a full course of radiotherapy for treatment of a rhabdomyosarcoma. Topics: Child; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Male; Osteoradionecrosis; Postoperative Care; Premedication; Radiation Injuries; Radiography; Temporal Bone; Tetracycline | 1988 |
Tetracyclines for controlling osteoradionecrosis in rat mandibles.
Topics: Animals; Mandible; Molar; Osteoradionecrosis; Radiation Injuries; Radiation Injuries, Experimental; Rats; Tetracycline; Tooth Extraction; Wound Healing | 1967 |