Abnormally high BLOOD GLUCOSE level.
Excerpt | Reference |
"This hyperglycemia is a part of the so-called "cancer-multistep-therapie"." | ( Graichen, D; Luppmann, HG, 1977) |
"Hyperglycemia is associated with a decrease in serum sodium concentration." | ( Goldstein, MB; Halperin, ML; Rolleston, FS; Roscoe, JM, 1975) |
"Hyperglycemia is known to worsen the outcome of transient global or forebrain ischemia." | ( Lundgren, J; Siesjö, BK; Smith, ML, 1992) |
"Thus, fasting hyperglycemia is sufficient to normalize insulin-stimulated muscle glucose uptake in NIDDM, and glucose is distributed normally to glycogenesis and glucose oxidation, possibly by normalization of GS and PDH." | ( Kelley, DE; Mandarino, LJ, 1990) |
"We conclude that hyperglycemia is associated with decreased histologic neuronal injury in this model of focal cerebral ischemia and may be protective when cerebral ischemia occurs from a focal insult." | ( Benson, GV; Kraft, SA; Larson, CP; Pearl, RG; Shuer, LM; Steinberg, GK, 1990) |
"2-DG-induced hyperglycemia is not dependent on only one of those three systems, it is dependent on all of them." | ( Gotoh, M; Iguchi, A; Mano, T; Matsunaga, H; Miura, H; Sakamoto, N; Uemura, K; Yatomi, A, 1989) |
"Hyperglycemia is one of the factors which could contribute considerably to the development of local ascorbic acid deficiency." | ( Aleo, JJ; Padh, H; Subramoniam, A, 1985) |
"After SAO early hyperglycemia is marked." | ( Valkenburg, PW; van der Meer, C; Versluys-Broers, JA, 1981) |
"Post-prandial hyperglycemia is common among diabetic patients." | ( Goto, Y; Ikeda, H; Matsuo, T; Odaka, H; Ohyama, T; Yamada, K, 1995) |
"To examine whether hyperglycemia is an independent regulator of adipose tissue lipolysis, we measured palmitate flux ([3H]palmitate) on two occasions in eight volunteers with insulin-dependent diabetes." | ( Cersosimo, E; Coppack, S; Jensen, M, 1993) |
"Hyperglycemia is a recognized complication of diarrhea-associated hemolytic-uremic syndrome (D + HUS)." | ( Brant, R; Leung, AK; Robson, WL; Stephure, DK; Trevenen, CL, 1995) |
"In summary, chronic hyperglycemia is associated with a fasting-induced paradoxical increase in glucose-potentiated insulin secretion." | ( Chen, C; Hosokawa, H; Hosokawa, YA; Leahy, JL, 1996) |
"Hyperglycemia is common in severely ill patients and is related principally to an increase in glucose production." | ( Brown, JA; Gore, DC, 1996) |
"Hyperglycemia is believed to be a major cause of diabetic vascular complications." | ( Horio, T; Kano, H; Kohno, M; Yasunari, K; Yokokawa, K; Yoshikawa, J, 1996) |
"Preischemic hyperglycemia is recognized to increase ischemic tissue acidosis and the present studies were undertaken to correlate depolarization and tissue acidosis during acute focal cerebral ischemia and hyperglycemia." | ( Hogan, MJ; Osuga, S, 1997) |
"Preexisting hyperglycemia is associated with enhanced reperfusion injury in the postischemic rat brain." | ( Huang, NC; Quast, MJ; Wei, J, 1997) |
"Severe hyperglycemia is uncommon in adult HIV-infected patients." | ( Kilby, JM; Tabereaux, PB, 1998) |
"Chronic hyperglycemia is then added to these risk markers." | ( Colwell, JA, 1997) |
"The control of hyperglycemia is of major importance in the treatment of patients with type 1 diabetes mellitus." | ( Brosh, D; Levy, Z; Rachmani, R; Ravid, M; Ravid-Safran, D, 1998) |
"Chronic hyperglycemia is a common feature of all forms of diabetes mellitus and may contribute greatly to the increased incidence of atherosclerosis, via promotion of both lipoprotein and tissue glycation, which may have atherogenic effects." | ( Cefalu, WT; Litwak, KN; Wagner, JD, 1998) |
"(a) Acute hyperglycemia is obtained from a condition of IIH by combined i." | ( Bazotte, RB; Hell, NS; Lopes, G; Souza, HM, 1996) |
"Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia." | ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999) |
"Hyperglycemia is considered a key causal factor in the development of diabetic vascular complications and can mediate its adverse effects through multiple pathways." | ( Gugliucci, A, 2000) |
"Stress hyperglycemia is common and likely to be associated with at least some of the same complications as hyperglycemia in true diabetes mellitus, such as poor wound healing and a higher infection rate." | ( Bistrian, BR; Malhotra, A; McCowen, KC, 2001) |
"Hyperglycemia is an important predictor of cardiovascular mortality in patients with diabetes." | ( Ghassemi, T; Gross, ER; Kersten, JR; Montgomery, MW; Pagel, PS; Toller, WG; Warltier, DC, 2001) |
"Chronic hyperglycemia is known to increase tissue glycation and diabetic complications, but controversy exists regarding the independent role of increased postprandial glucose excursions." | ( Beisswenger, PJ; Howell, SK; O'Dell, RM; Szwergold, BS; Touchette, AD; Wood, ME, 2001) |
"Hyperglycemia is likely to be one of the important determinants of ion transport as it is known to induce oxidative stress and may thus enhance non-specific permeability of membranes." | ( Güven, M; Hatemi, H; Onaran, I; Sultuybek, G; Ulutin, T, 2001) |
"This state of hyperglycemia is most obviously directed to satisfy the increased need of the injured organs and of the inflammatory cells." | ( Avignon, A; Monnier, L, 2001) |
"4." | ( Girija, AS; Sabitha, KM; Vargese, KS, 2001) |
"Chronic hyperglycemia is known to lead to a progressively further impaired insulin response and to hasten the development of complications in patients with type 2 diabetes, a notion referred as glucose toxicity." | ( Adachi, T; Fujimoto, S; Mukai, E; Nunoi, K; Okamoto, Y; Oku, A; Seino, Y; Shihara, N; Suzuki, N; Tamon, A; Tsuda, K; Yasuda, K, 2002) |
"Hyperglycemia is considered a primary cause of diabetic vascular complications." | ( Bernath, K; Madar, Z; Marikovsky, M; Noyman, I; Sasson, S; Seger, R; Stark, AH, 2002) |
"Hyperglycemia is associated with generation of reactive oxygen species (ROS), and this action may contribute to accelerated atherogenesis." | ( Gross, ER; Hettrick, DA; Kersten, JR; Kress, TT; LaDisa, JF; Olson, LE; Pagel, PS; Warltier, DC; Weihrauch, D, 2003) |
"Hyperglycemia is associated with detriments in immune function and impaired wound healing." | ( Gore, DC; Herndon, DN; Wolf, SE; Wolfe, RR, 2003) |
"Postprandial hyperglycemia is frequently associated with visceral obesity which plays a key role in metabolic abnormalities such as dyslipidemia and hypertension." | ( Yamada, K, 2003) |
"Hyperglycemia is a crucial factor in the development of diabetic nephropathy." | ( Lincoln, TM; Murphy-Ullrich, JE; Wang, S; Wu, X, 2003) |
"Stress hyperglycemia is frequent in critically ill patients." | ( Coopmans, W; Giulietti, AP; Mathieu, C; Michalaki, M; Van den Berghe, G; Van Herck, E; Weekers, F, 2003) |
"Hyperglycemia is a major risk factor for a poor outcome after major surgery in patients with type 2 diabetes." | ( Gallwitz, B; Holst, JJ; Meier, JJ; Michaely, M; Nauck, MA; Schmidt, WE; Senkal, M; Weyhe, D; Zumtobel, V, 2004) |
"Hyperglycemia is considered a primary cause of diabetic vascular complications and is associated with oxidative stress, impaired trace element and lipid metabolism as well as pancreatic enzyme abnormalities." | ( Abou-Seif, MA; Youssef, AA, 2004) |
"Acute and chronic hyperglycemia are proinflammatory states, but the status of proinflammatory cytokines and markers of oxidative stress and cardiovascular risks is not known in hyperglycemic crises of diabetic ketoacidosis (DKA) and nonketotic hyperglycemia (NKH)." | ( Cuervo, R; Kitabchi, AE; Stentz, FB; Umpierrez, GE, 2004) |
"Hyperglycemia is common in critically ill hospitalized patients, and it is associated with adverse outcomes, including increased mortality." | ( Lau, J; Pittas, AG; Siegel, RD, 2004) |
"Hyperglycemia is implicated to play a major role in development of diabetic neuropathy." | ( Arun, KH; Kaul, CL; Saini, AK; Sharma, SS, 2004) |
"Hyperglycemia is a major independent risk factor for diabetic macrovascular disease." | ( Barzilai, N; Berg, AH; Brownlee, M; Combs, TP; Du, X; Fantus, IG; Giacca, A; Hawkins, M; Iyengar, P; Lam, TK; Li, W; Lin, Y; Rajala, MW; Rhodes, CJ; Rollman, B; Scherer, PE, 2005) |
"Conversely, chronic hyperglycemia is accompanied by progressive increases in basal HGP and is a major contributor to hyperglycemia in both type 1 and type 2 diabetes by mechanisms that are poorly understood." | ( Friedman, JE; Janssen, RC; Pagliassotti, M; Qiao, L; Shao, J, 2005) |
"Hyperglycemia is an activating signal for cardiac PKC isozymes that modulate a myriad of cell events including cell death and survival." | ( Begley, R; Kang, BP; Liu, J; Malhotra, A; Meggs, LG; Mochly-Rosen, D; Rana, I; Yang, G, 2005) |
"We propose that hyperglycemia is the driving force that aggravates overproduction of VLDL1 in DM2." | ( Adiels, M; Borén, J; Caslake, MJ; Olofsson, SO; Packard, C; Soro, A; Stewart, P; Taskinen, MR; Wennberg, B; Westerbacka, J, 2005) |
"Hyperglycemia is a common problem encountered in hospitalized patients, especially in critically ill patients and those with diabetes mellitus." | ( Alaniz, C; Btaiche, IF; Butler, SO, 2005) |
"Hyperglycemia is becoming recognized as an important risk factor for microvascular dysfunction." | ( Demirci, C; Ince, C; Koeman, A; Vink, H; Zuurbier, CJ, 2005) |
"Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications." | ( Han, J; Hiebert, LM; Mandal, AK, 2005) |
"Maternal hyperglycemia is a non-specific teratogen." | ( Garne, E; Johansen, MN, 2005) |
"Hyperglycemia is supposed to be one of the factors inducing hepatic fibrogenesis, but the mechanism has not been fully clarified." | ( Enjoji, M; Fukushima, M; Inoguchi, T; Iwao, M; Kohjima, M; Kotoh, K; Nakamuta, M; Sonta, T; Sugimoto, R; Tsuruta, S, 2005) |
"Hyperglycemia is prevalent in chronic kidney disease; however, the relationship between glycosylated hemoglobin (HbA(1c)) as a marker of chronic hyperglycemia and outcomes has not been studied in nondiabetic chronic kidney disease." | ( Beck, GJ; Collins, AJ; Greene, T; Kusek, JW; Levey, AS; Menon, V; Pereira, AA; Sarnak, MJ; Wang, X, 2005) |
"Hyperglycemia is associated with increased mortality and morbidity in acute ischemic stroke." | ( Chaudhuri, A; Dandona, P; Garg, R; Munschauer, F, 2006) |
"Hyperglycemia is associated with metabolic disturbances affecting cell redox potential, particularly the NADPH/NADP+ ratio and reduced glutathione levels." | ( Baiza-Gutman, LA; Cruz, M; Díaz-Flores, M; Durán-Reyes, G; Galván, RE; Gutiérrez, M; Ibáñez-Hernández, MA; Medina-Navarro, R; Ortega-Camarillo, C; Pascoe-Lira, D; Vilar-Rojas, C, 2006) |
"Hyperglycemia is common after subarachnoid hemorrhage (SAH)." | ( Claassen, J; Fernandez, A; Frontera, JA; Mayer, SA; Ostapkovich, ND; Parra, A; Schmidt, M; Schumacher, HC; Temes, R; Wartenberg, K, 2006) |
"Since chronic hyperglycemia is central to diabetic complications, and poorly differentiated cells are oxidatively more vulnerable, we currently investigated the effect of glycemic status on MG-induced apoptosis in naïve (nPC12) cells focusing on glutathione-to-glutathione disulfide (GSH/GSSG) redox signaling." | ( Aw, TY; Okayama, N; Okouchi, M, 2005) |
"Hyperglycemia is a common feature of the critically ill patient and has been associated with increased mortality." | ( Langouche, L; Van den Berghe, G, 2006) |
"Hyperglycemia is common in patients treated with atypical antipsychotics and thought to be euglycemic." | ( Gulanski, B; Rosenheck, R; Sernyak, MJ, 2005) |
"Hyperglycemia is associated with increased susceptibility to atherothrombotic stimuli." | ( Gouverneur, MC; Hoekstra, JB; Holleman, F; Kastelein, JJ; Levi, M; Meijers, JC; Mooij, HL; Nieuwdorp, M; Stroes, ES; van Haeften, TW; van Lieshout, MH; Vink, H, 2006) |
"Hyperglycemia is a causal factor in the development of the vascular complications of diabetes." | ( Ape, AU; Beltramo, E; Berrone, E; Porta, M; Solimine, C, 2006) |
"Since hyperglycemia is much more common than intermittent hypoglycemia during early childhood diabetes, it is important to determine if hyperglycemia affects brain growth and development." | ( Hanna, SK; Malone, JI; Saporta, S, 2006) |
"The risk of hyperglycemia is increased in patients treated with ddI + TDF, particularly in those with lower weight." | ( Barreiro, P; Barrios, A; Blanco, F; García-Benayas, T; González-Lahoz, J; Maida, I; Rendón, AL; Rivas, P; Rodríguez-Novóa, S; Soriano, V, 2006) |
"Hyperglycemia is an independent risk factor for increased mortality of critically ill surgical patients, but despite the recognized clinical benefits of early insulin treatment, there is a lack of understanding of the cellular and molecular mechanisms behind this phenomenon." | ( Miller, FN; Polk, HC; Tucker, C; Turina, M, 2006) |
"Chronic hyperglycemia is an established risk factor for endothelial damage." | ( Ebihara, T; Furukawa, M; Kinoshita, K; Kitahata, Y; Noda, A; Sakurai, A; Tanjoh, K; Utagawa, A, 2006) |
"Stress-induced hyperglycemia is necessary for maximal rates of survival after severe hemorrhage; however, the responsible mechanisms are not clear." | ( Bounelis, P; Chatham, JC; Chaudry, I; Marchase, RB; Yang, S; Zou, LY, 2006) |
"Postprandial hyperglycemia is often inadequately assessed in diabetes management." | ( Buse, JB; Button, EA; Dungan, KM; Kato, S; Kelly, MM; Largay, J; Wittlin, S, 2006) |
"Acute hyperglycemia is associated with excess morbidity and mortality in acute cardiovascular illness in both diabetic and nondiabetic patients." | ( Zarich, SW, 2006) |
"Hyperglycemia is an independent risk factor for mortality in both diabetic patients and nondiabetic patients with ACS." | ( Chirkov, YY; Heresztyn, T; Holmes, AS; Horowitz, JD; Kucia, AM; Stewart, S; Willoughby, SR; Worthley, MI; Zeitz, CJ, 2007) |
"Hypertension and hyperglycemia are risk factors for incident retinopathy." | ( Amirul Islam, FM; Cotch, MF; Couper, DJ; Hubbard, LD; Klein, BE; Klein, R; Sharrett, AR; Wong, TY, 2007) |
"Hyperglycemia is common in hospitalized patients; however, glycemic control obtained during hospitalization is often suboptimal." | ( Bdolah-Abram, T; Elinav, H; Glaser, B; Leibowitz, G; Raz, I; Szalat, A; Wolf, Z, 2007) |
"Hyperglycemia is an independent risk factor for diabetic heart failure." | ( Kobayashi, S; Liang, Q; Mao, K; O'Connell, TD; Patterson, C; Wang, X; Zheng, H, 2007) |
"Hyperglycemia is the major cause of diabetic angiopathy." | ( Birnbaum, DE; Haubner, F; Lehle, K; Münzel, D; Preuner, JG; Schmid, C, 2007) |
"Hyperglycemia is a causative factor in the pathogenesis of diabetic nephropathy." | ( Chen, X; Gilbert, RE; Kelly, DJ; Pollock, CA; Qi, W; Schache, M; Waltham, M; Zhang, Y, 2007) |
"Hyperglycemia is a defining feature of Type 1 and 2 diabetes." | ( Bruce, CR; Cederberg, A; Cooney, GJ; Hoy, AJ; James, DE; Kraegen, EW; Turner, N, 2007) |
"Hyperglycemia is a major risk factor for atherosclerotic disease." | ( Cao, WM; Chen, K; Imachi, H; Ishida, T; Matsumoto, K; Murao, K; Nishiuchi, T; Wong, NC; Yu, X, 2008) |
"Hyperglycemia is an independent risk factor for development of vascular diabetic complications." | ( Bhattacharyya, S; Hoppe, G; Krukovets, I; Marinic, TE; Stenina, OI, 2008) |
"Hyperglycemia is the most important factor for the onset and progress of diabetic complications." | ( Ho, CT; Lo, CY; Tan, D; Wang, Y, 2008) |
"Significant hyperglycemia is present in pediatric intensive care patients and may be underestimated by intermittent laboratory monitoring." | ( Allen, HF; Brenner, D; McKiernan, CA; Rake, A; Roy, M, 2008) |
"Hyperglycemia is an independent risk factor for development of diabetic vascular complications." | ( Dabir, P; Krukovets, I; Marinic, TE; Stenina, OI, 2008) |
"The effect of hyperglycemia is unknown." | ( Ackermans, MT; Blümer, RM; Endert, E; Sauerwein, HP; Stegenga, ME; Tanck, MW; van der Crabben, SN; van der Poll, T, 2008) |
"Hyperglycemia is associated with higher HMGB1 levels and lung damage in sepsis." | ( Hagiwara, S; Hasegawa, A; Iwasaka, H; Koga, H; Noguchi, T, 2008) |
"Even mild hyperglycemia is associated with macrovascular disease." | ( Nadeau, DA; Unger, J, 2007) |
"Hyperglycemia is a common complication of prematurity, which requires attention because of its high prevalence and multiple consequences." | ( Ertl, T; Gaal, V; Gyarmati, J; Kovacs, GL; Tokes-Fuzesi, M; Vida, G, 2009) |
"Postprandial hyperglycemia is one of the features of type 2 diabetes." | ( Fujiwara, T; Hagisawa, Y; Izumi, M; Ohsumi, J; Okuno, A; Takahashi, K; Yoshida, T, 2008) |
"Maternal hyperglycemia is associated with decreased plasma fetal cholesterol levels in term infants." | ( Gordon, Y; Parker, CR; Patterson, TM, 2009) |
"Hyperglycemia is a common side effect, but ketoacidosis is observed rarely." | ( Cağdaş, DN; Cakal, E; Paç, FA, 2008) |
"Hyperglycemia is an on-target side effect of many inhibitors of PI3K/Akt signaling including the specific PI3K inhibitor PX-866." | ( Halter, RJ; Ihle, NT; Kirkpatrick, L; Lemos, R; Oh, J; Powis, G; Schwartz, D; Wipf, P, 2009) |
"Postprandial hyperglycemia is considerably reduced in adolescents with T1DM when treated with fixed-dose premeal pramlintide, and precisely calculated postmeal insulin, without significant side effects." | ( Hassan, K; Heptulla, RA, 2009) |
"Early neonatal hyperglycemia is common among very low birth weight (VLBW) neonates." | ( Bottino, M; Cowett, RM; Sinclair, JC, 2009) |
"Aging-related hyperglycemia is associated with increased oxidative stress and diminished muscle glucose transporter-4 (Glut4) that may be regulated, at least in part, by the mitogen-activated protein kinases (MAPK)." | ( Blough, ER; Desai, DH; Gutta, AK; Kakarla, SK; Katta, A; Paturi, S; Rice, KM; Walker, EM; Wu, M, 2009) |
"Hyperglycemia is noted in up to 60% of stroke patients." | ( Casaubon, LK; Ennis, M; Kapral, MK; Lam, N; Peeva, V; Saltman, A; Silver, FL, 2008) |
"Hyperglycemia is frequently observed in nondiabetic patients during acute illness." | ( Asai, N; Hagiwara, S; Hasegawa, A; Iwasaka, H; Noguchi, T, 2009) |
"Preventing harmful hyperglycemia is important in critical illness." | ( Arai, H; Bailey, M; Egi, M; Katayama, H; Morita, K; Naomoto, Y; Toda, Y; Yamatsuji, T; Yokoyama, M, 2010) |
"Hyperglycemia is often a problem in patients who receive continuous enteral nutrition." | ( Burkitt, D; Cook, A; McDonald, L; Sublett, L, 2009) |
"Hyperglycemia is a recognized risk factor for cardiovascular disease in diabetes." | ( Agardh, CD; Agardh, E; Fredrikson, GN; Gomez, MF; González Bosc, LV; Hultgårdh-Nilsson, A; Nilsson, J; Nilsson-Berglund, LM; Nilsson-Ohman, J; Salehi, A; Sigvardsson, M; Smith, ML; Wamhoff, BR; Zetterqvist, AV, 2010) |
"Hyperglycemia is associated with poor outcomes in critically ill and postsurgical patients." | ( Akhtar, S; Barash, PG; Inzucchi, SE, 2010) |
"Chronic hyperglycemia is a major contributor to in vivo platelet activation in diabetes mellitus." | ( Averna, M; Ciabattoni, G; Consoli, A; Davì, G; Di Fulvio, P; Formoso, G; Ganci, A; Lattanzio, S; Lauro, R; Miccoli, R; Patrono, C; Pulizzi, N; Santilli, F; Sbraccia, P, 2010) |
"Postprandial hyperglycemia is associated with enhanced lipid peroxidation and platelet activation in early type 2 diabetes." | ( Averna, M; Ciabattoni, G; Consoli, A; Davì, G; Di Fulvio, P; Formoso, G; Ganci, A; Lattanzio, S; Lauro, R; Miccoli, R; Patrono, C; Pulizzi, N; Santilli, F; Sbraccia, P, 2010) |
"Hyperglycemia is the major cause of diabetic angiopathy." | ( Jin, HB; Li, J; Su, Y; Sun, YM; Wang, LF, 2010) |
"Hyperglycemia is a major risk factor for atherosclerotic disease." | ( Hosomi, N; Imachi, H; Ishida, T; Iwama, H; Li, J; Masugata, H; Murao, K; Nishiuchi, T; Yu, X; Zhang, GX, 2010) |
"Hyperglycemia is known to inhibit ischemic and anesthetic preconditioning." | ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2010) |
"Hyperglycemia is commonplace in the critically ill patient and is associated with worse outcomes." | ( Brealey, D; Singer, M, 2009) |
"Although hyperglycemia is a well-recognized risk factor in the context of cardiac surgery, the relevance of perioperative glycemic control for patients undergoing major noncardiac operations has received little attention." | ( Carvalho, G; Hassanain, M; Lattermann, R; Matsukawa, T; Metrakos, P; Sato, H; Sato, T; Schricker, T, 2010) |
"Hyperglycemia is acknowledged as an independent risk factor for developing diabetes-associated atherosclerosis." | ( Abu-Taha, M; Azcutia, V; Luscinskas, FW; Matesanz, N; Peiró, C; Rodríguez-Mañas, L; Romacho, T; Sánchez-Ferrer, CF; Sanz, MJ; Vázquez-Bella, M, 2010) |
"Hyperglycemia is associated with hemodynamic changes in type 1 diabetes (DM), acting in part through renin-angiotensin system activation." | ( Bradley, TJ; Cherney, DZ; Dekker, MG; Lai, V; Miller, JA; Reich, HN; Scholey, JW; Sochett, EB; Zinman, B, 2010) |
"Hyperglycemia is one of the major factors for hemorrhagic transformation after ischemic stroke." | ( Chen, CH; Liu, WW; Manaenko, A; Ostrowki, RP; Tang, J; Zhan, Y; Zhang, JH, 2010) |
"Poststroke hyperglycemia is common and is associated with increased risk of death and dependence, but appropriate management remains uncertain." | ( Condon, B; Hadley, D; Macfarlane, JA; McCormick, M; McLean, JR; Muir, KW, 2010) |
"Hyperglycemia is an indication of poor outcome for heart attack patients, even for nondiabetic patients with stress-induced hyperglycemia." | ( Cheng, WT; Chung, SK; Chung, SS; Hou, XY; Kravtsov, GM; Tang, WH; Tong, XY, 2010) |
"Postprandial hyperglycemia is known to be associated with increasing cardiovascular mortality in type 2 diabetes mellitus patients." | ( Ban, N; Endo, K; Kawana, H; Miyashita, Y; Murano, T; Nagayama, D; Nagumo, A; Ohira, M; Oyama, T; Saiki, A; Shirai, K; Watanabe, H; Yamaguchi, T, 2011) |
"Hyperglycemia is implicated both in micro- and macro-vascular complications in diabetes mellitus." | ( Cardile, V; Castorina, A; D'Agata, V; Giunta, S; Mazzone, V, 2010) |
"Postprandial hyperglycemia is one of the important factors contributing to an increase in the circulating pro-inflammatory cytokine levels." | ( Abiko, A; Araki, S; Haneda, M; Itoh, H; Koya, D; Maegawa, H; Nakagawa, A; Nishizawa, M; Uzu, T; Yokomaku, Y; Yokoyama, H, 2011) |
"Hyperglycemia is the main factor which induces oxidative stress mainly by activation of NADPH oxidase in monocytes of diabetic patients." | ( Dong, Y; Guo, H; Huang, X; Jiang, L; Li, D; Li, J; Liu, J; Man, Y; Pan, Q; Sun, M; Wang, S, 2011) |
"Hyperglycemia is associated with greater hematoma expansion and poor clinical outcomes after intracerebral hemorrhage." | ( Blair, P; Chilcote, TJ; Clermont, AC; Feener, EP; Flaumenhaft, R; Gao, BB; Liu, J; Sinha, S, 2011) |
"Acute hyperglycemia is considered as a pro-inflammatory state and is related to an adverse outcome in critically ill adults." | ( Härtel, C; Holterhus, PM; Schultz, C; Temming, P; Thonnissen, S; Tröger, B, 2012) |
"Postprandial hyperglycemia is an important clinical problem in cystic fibrosis (CF), but the contribution of fat malabsorption, rapid gastric emptying, and the incretin axis has not been widely considered." | ( Chapman, I; Greville, H; Hetzel, D; Horowitz, M; Jones, KL; Kuo, P; Maddox, A; Rayner, CK; Russo, A; Stevens, JE; Wishart, JM, 2011) |
"Hyperglycemia is a known exacerbating factor in ischemic stroke." | ( Fujita-Hamabe, W; Harada, S; Tokuyama, S, 2011) |
"Hyperglycemia is an important confounder and should be evaluated in studies of OSA and autonomic function." | ( Artibee, K; Bagai, K; Diedrich, A; Elasy, T; Feldman, EL; Garland, E; Malow, BA; Peltier, AC; Robertson, D; Shi, Y; Wang, L, 2012) |
"Hyperglycemia is an exceptional manifestation of methylmalonic acidemia (MMA)." | ( Aida, R; Hanene, B; Ichraf, K; Ilhem, T; Imen, M; Naziha, K; Neziha, GK, 2012) |
"Hyperglycemia is an exceptional manifestation of MMA and could be a seriousness marker." | ( Aida, R; Hanene, B; Ichraf, K; Ilhem, T; Imen, M; Naziha, K; Neziha, GK, 2012) |
"Hyperglycemia is among the major side effects of dexamethasone (DEX)." | ( Friday, E; Ledet, J; Turturro, F, 2011) |
"Early neonatal hyperglycemia is common among very low birth weight (VLBW) neonates." | ( Bottino, M; Cowett, RM; Sinclair, JC, 2011) |
"Hyperglycemia is associated with a decreased tolerance to ischemia and an increased severity of renal ischemia reperfusion (I/R) injury." | ( Caetano, AM; Castiglia, YM; de Carvalho, LR; de Oliveira, C; de Souza, AV; Deffune, E; Golim, MA; Vianna Filho, PT; Vianna, PT, 2011) |
"Hyperglycemia is a common complication found in the burn population because hepatic glucose production and catecholamine-mediated hepatic glycogenolysis are augmented." | ( Børsheim, E; Elijah, IE; Finnerty, CC; Herndon, DN; Maybauer, DM; Maybauer, MO, 2012) |
"Hyperglycemia is one of the main metabolic disturbances in critically-ill patients and is associated with increased morbidity and mortality." | ( Grau Carmona, T; Juan Díaz, M; Vaquerizo Alonso, C, 2011) |
"Hyperglycemia is one of the main metabolic disturbances in critically-ill patients and is associated with increased morbidity and mortality." | ( Grau Carmona, T; Juan Díaz, M; Vaquerizo Alonso, C, 2011) |
"Perioperative hyperglycemia is common in patients with type 2 diabetes undergoing Coronary Artery Bypass Graft (CABG) surgery and there is a direct relation between postoperative hyperglycemia and mortality rate in these patients." | ( Aarabi, M; Baradari, AG; Emami Zeydi, A; Ghafari, R, 2011) |
"Hyperglycemia is a principal characteristic of diabetes and influences many cellular functions." | ( Shibasaki, M; Tahara, A; Tomura, Y; Tsukada, J; Yatsu, T, 2012) |
"It seems that hyperglycemia is not an important risk factor for future diabetes." | ( Bordbar, MR; Haghpanah, S; Karamizadeh, Z; Karimi, M; Omrani, GH; Taj-Aldini, R, 2012) |
"Hyperglycemia is associated with several common neurological syndromes." | ( Arnason, T; Savedia-Cayabyab, S; Senior, P; Slabu, H, 2011) |
"Since hyperglycemia is involved in the "aspirin resistance" occurring in diabetes, we aimed at evaluating whether high glucose interferes with the aspirin-induced inhibition of thromboxane synthesis and/or activation of the nitric oxide (NO)/cGMP/cGMP-dependent protein kinase (PKG) pathway in platelets." | ( Anfossi, G; Barale, C; Cavalot, F; Doronzo, G; Mattiello, L; Pagliarino, A; Russo, I; Trovati, M; Viretto, M, 2012) |
"Hyperglycemia is considered the major pathogenic factor for the development of diabetic retinopathy and is associated with increased oxidative/nitrosative stress in the retina." | ( Ambrósio, AF; Aveleira, CA; Baptista, FI; Castilho, Á; Fernandes, CR; Leal, EC; Meirinhos, RI; Simões, NF, 2012) |
"This hyperglycemia is associated with impaired pancreatic β-cell function, loss of pancreatic β-cell mass, and decreased responsiveness of liver and extrahepatic tissues to the actions of insulin and glucose." | ( Printz, RL; Shiota, M, 2012) |
"Early morning hyperglycemia is frequent among children and adolescents with type 1 diabetes." | ( Holl, R; Kapellen, T; Stachow, R; von Schütz, W; Wolf, J, 2012) |
"Hyperglycemia is associated with enhanced cortical toxicity and larger infarct volumes following focal cerebral ischemia." | ( Johnston, KC; Southerland, AM, 2012) |
"When diabetes or hyperglycemia is addressed early and consistently, the hospital stay can serve as a potential window of opportunity for reinforcing self-care behaviors that reduce long-term complications." | ( Dungan, K; Moore, J, 2012) |
"Hyperglycemia is independently related with excessive morbidity and mortality in cardiovascular disorders." | ( Kumar, PH; Murugan, PS; Puhari, SS; Ramprasath, T; Selvam, GS; Vasudevan, V, 2012) |
"Hyperglycemia is a result of impaired insulin action on glucose production and disposal, and a major target of antidiabetic therapies." | ( Barlow, JL; Bhargava, P; Dai, L; Gangl, MR; Inouye, K; Jacobi, D; Ji, Y; Lee, CH; Liu, S; McKenzie, AN; Mizgerd, JP; Qi, L; Shi, H; Stanya, KJ, 2013) |
"Hyperglycemia is a consequence of chronic uncontrolled diabetes and it is postulated to produce neuropathic pain." | ( Jain, G; Sharma, SS; Singh, JN, 2013) |
"Fasting hyperglycemia is due to excessive glucose production in people with either IFG/NGT or IFG/IGT." | ( Barosa, C; Basu, A; Basu, R; Carter, R; Dube, S; Jones, J; Rizza, RA, 2013) |
"Hyperglycemia is a hallmark of diabetes that is associated with diabetic complications and a reduction of lifespan." | ( Boll, M; Fitzenberger, E; Wenzel, U, 2013) |
"Hyperglycemia is the proximal detonator of systemic and local toxic effectors including proinflammation, acute-phase proteins elevation, and spillover of reactive oxygen and nitrogen species." | ( Berlanga-Acosta, J; García-Siverio, M; Guillen-Nieto, G; Herrera-Martínez, L; López-Mola, E; Schultz, GS, 2013) |
"Transient hyperglycemia is associated with an increase in IRI." | ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
"Hyperglycemia is a common complication of diabetes melitis (DM) and in the absence of metabolic decompensation is a common finding in the Emergency Department (ED)." | ( Akkaş, M; Akman, C; Aksoy, DY; Aksu, NM; Ozmen, MM; Usman, A; Yildiz, BO; Yilmaz, H, 2013) |
"Hyperglycemia is associated with advanced glycation end products (AGEs)." | ( Chang, WC; Cheng, YH; Hsu, WH; Lee, BH; Lee, CC; Wu, SC, 2013) |
"Hyperglycemia is a primary factor that disturbs podocyte function in the glomerular filtration process; this disturbance leads to the development of diabetic nephropathy, and ultimately, renal failure." | ( Angielski, S; Audzeyenka, I; Jankowski, M; Piwkowska, A; Rogacka, D, 2014) |
"Spontaneous hyperglycemia is common in critically ill patients and is associated with an adverse outcome compared to normoglycemia." | ( Krogh-Madsen, R; Møller, K; Nielsen, ST, 2015) |
"Postprandial hyperglycemia is one of the earliest abnormalities of glucose homeostasis associated with type 2 diabetes (T2D)." | ( Kumar, V; Priscilla, DH; Roy, D; Suresh, A; Thirumurugan, K, 2014) |
"Hyperglycemia is not identified as a significant prognostic factor for idiopathic sudden sensorineural hearing loss in any literature." | ( Choi, MG; Kim, DK; Lee, JH; Lee, JS; Park, CH; Ryu, OH, 2014) |
"Hyperglycemia is a key feature in diabetes." | ( Kim, HJ; Lee, W; Yun, JM, 2014) |
"Hyperglycemia is common during emergency craniotomy in TBI patients." | ( Bhattacharjee, S; Gozi, NK; Layek, A; Maitra, S; Pal, S; Sen, S, 2014) |
"Hyperglycemia is considered to be associated with poor outcomes of ischemic stroke." | ( Chen, NH; Guo, XF; He, WB; Zhang, S; Zuo, W, 2014) |
"Nonketotic hyperglycemia is a rare cause of hemichorea." | ( Guo, Y; Ji, XF; Li, M; Liu, X; Miao, YW; Sun, XP, 2014) |
"Postprandial hyperglycemia is a risk factor for cardiovascular disease and mortality." | ( Ako, J; Arao, K; Fujiwara, T; Funayama, H; Kakei, M; Katayama, T; Mitsuhashi, T; Momomura, S; Nakamura, T; Sakakura, K; Sugawara, Y; Tsukui, T; Wada, H; Yamada, H; Yoshida, M, 2015) |
"Hyperglycemia is a critical risk factor for development and progression of breast cancer." | ( Gupta, C; Kaur, J; Tikoo, K, 2014) |
"Hyperglycemia is the main feature for the diagnosis of this disease." | ( Antonioli, R; Bogo, MR; Bonan, CD; Capiotti, KM; Da Silva, RS; Kist, LW, 2014) |
"Hyperglycemia is the primary cause of the majority of diabetes complications, including diabetic retinopathy (DR)." | ( Gurel, Z; Pratt, MR; Sheibani, N; Zaro, BW, 2014) |
"Hyperglycemia is the main cause of several diabetic complications, and its consequences in terms of melatonin production were assessed." | ( Afeche, SC; Amaral, FG; Barone, M; Bordin, S; Cipolla-Neto, J; do Carmo Buonfiglio, D; Lima, L; Menna-Barreto, L; Peliciari-Garcia, RA; Peres, R; Reiter, RJ; Scavone, C; Scialfa, JH; Turati, AO, 2014) |
"Hyperglycemia is associated with increased risk of all-site cancer that may be mediated through activation of the renin-angiotensin-system (RAS) and 3-hydroxy-3-methyl-glutaryl-coenzyme-A-reductase (HMGCR) pathways." | ( Chan, JC; Cheung, KK; Chow, CC; Kong, AP; Lee, HM; Luk, A; Ma, RC; Ozaki, R; So, WY; Xu, G; Yang, X; Yu, L, 2014) |
"Hyperglycemia is involved in the diabetic complication of different organs and can elevate serum osmolarity." | ( Calleros, L; del Nogal, M; Griera, M; Rodriguez-Puyol, D; Rodriguez-Puyol, M; Ruiz-Torres, MP; Troyano, N, 2014) |
"Additionally, since hyperglycemia is considered the main trigger of diabetic complications, we investigated whether prolonged exposure to elevated glucose could affect the content and distribution of motor proteins in retinal cultures." | ( Almeida, RD; Ambrósio, AF; Baptista, FI; Elvas, F; Martins, T; Pinto, MJ, 2014) |
"Postprandial hyperglycemia is considered a major predictor of diabetic complications, and its reduction represents a specific treatment target in Type 1 and 2 diabetes." | ( Herzog, B; Jordi, J; Lutz, TA; Verrey, F, 2014) |
"Hyperglycemia is common in hospitalized patients with and without prior history of diabetes and is an independent marker of morbidity and mortality in critically and noncritically ill patients." | ( Schwartz, S; Umpierrez, GE, 2014) |
"Chronic hyperglycemia is an important risk factor involved in the onset and progression of diabetic retinopathy (DR)." | ( Chang, KC; LaBarbera, DV; Petrash, JM; Snow, A, 2015) |
"Long-term hyperglycemia is a typical symptom of diabetes mellitus (DM) which can cause a high level of protein glycation and lead to the formation of advanced glycation end products (AGEs)." | ( Huang, K; Huang, L; Lei, X; Peng, A; Wang, H; Yang, X; Zheng, L, 2015) |
"Perioperative hyperglycemia is associated with postoperative complications after major surgery." | ( Devries, JH; Eshuis, JH; Hermanides, J; Hollmann, MW; Houweling, PL; Polderman, JA; Preckel, B; Van Velzen, L; Wasmoeth, LG, 2015) |
"Although hyperglycemia is common in patients with acute myocardial infarction (MI), the underlying mechanisms are largely unknown." | ( Chen, Y; Han, H; Liu, B; Wang, J; Xu, F; Xue, M; Yuan, Q, 2015) |
"Hyperglycemia is known to inhibit myocardial anesthetic postconditioning." | ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2015) |
"Hyperglycemia is commonly associated with microcirculation dysfunction." | ( Gao, D; Han, P; Li, X; Liu, S; Yang, S; Zhang, W, 2015) |
"Evidence suggests hyperglycemia is associated with worse outcomes in glioblastoma (GB)." | ( Chung, C; Kiehl, TR; Laperriere, N; Lovblom, LE; Mason, W; McNamara, MG; Ménard, C; Millar, BA; Perkins, BA; Tieu, MT, 2015) |
"Although hyperglycemia is the main instigator in the development of diabetic retinopathy, dyslipidemia is also considered to play an important role." | ( Kowluru, A; Kowluru, RA; Kumar, B, 2015) |
"Hyperglycemia is common in critically ill and surgical patients, as are core temperature disturbances." | ( Ino, H; Ishiyama, T; Iwashita, H; Masamune, T; Matsukawa, T; Oguchi, T; Okuyama, K; Sato, H; Sessler, DI; Wada, K, 2015) |
"Hyperglycemia is a common metabolic problem in extremely low-birth-weight preterm infants." | ( Bhandari, V; Ennis, K; Gisslen, T; Rao, R, 2015) |
"However, stress hyperglycemia is not predictive of early febrile seizure recurrence in the emergency department." | ( Cho, HR; Kim, JH; Ko, TS; Lee, JS; Lee, JY; Ryu, JM; Yum, MS, 2016) |
"Postprandial hyperglycemia is a direct and independent risk factor for cardiovascular diseases." | ( Hase, T; Jokura, H; Shimotoyodome, A; Umeda, M; Watanabe, I, 2015) |
"Hyperglycemia is the driving force for the development of diabetic retinopathy." | ( Li, XF; Li, YB; Su, Y; Sun, YM; Wan, TT, 2015) |
"Hyperglycemia is associated with oxidative stress, which accelerates cardiovascular complications." | ( Leikin-Frenkel, A; Madar, Z; Magzal, F; Markman, G; Szuchman-Sapir, A; Tamir, S; Yehuda, I, 2016) |
"Hyperglycemia is common after acute stroke and is associated with a worse outcome of stroke." | ( Chen, CJ; Chen, WY; Kuan, YH; Lai, NW; Liu, CH; Mao, FC; Wu, CC, 2016) |
"Hyperglycemia is one of the major causes of suppressed angiogenesis and impaired wound healing leading to chronic wounds." | ( Bahadır, E; Çelik, A; Gülçiçek, OB; Karagöz, A; Özsavcı, D; Şirvancı, S; Solmaz, A; Yeğen, BÇ; Yiğitbaş, H, 2016) |
"Hyperglycemia is a major public health problem worldwide and there is increasing demand for prevention of postprandial hyperglycemia in diabetic, prediabetic, and healthy humans." | ( Hashizume, K; Okahara, F; Osaki, N; Shimotoyodome, A; Suzuki, J, 2016) |
"Admission hyperglycemia is an independent risk factor for poor outcome of ischemic stroke." | ( Hattori, N; Kuroki, T; Shimada, Y; Shimura, H; Tanaka, R; Ueno, Y; Urabe, T; Yamashiro, K, 2016) |
"Hyperglycemia is closely associated with prediabetes and Type 2 Diabetes Mellitus." | ( Armugam, A; Jeyaseelan, K; Karolina, DS; Kaur, C; Silambarasan, M; Tan, JR, 2016) |
"Hyperglycemia is a major complication of parenteral nutrition (PN)." | ( Amin, T; Azzam, A; Hakeam, HA; Mulia, HA, 2017) |
"Uncontrolled hyperglycemia is therefore a contra-indication for bone implant placement." | ( Ajami, E; Bell, S; Davies, JE; Liddell, RS, 2016) |
"Hypernatremia and hyperglycemia are highly prevalent in preterm infants during the first week after birth, and both can lead to hyperosmolarity and osmotic shifts." | ( Bermick, J; Dechert, RE; Sarkar, S, 2016) |
"Hyperglycemia is acknowledged as a pro-inflammatory condition and a major cause of vascular damage." | ( Azcutia, V; Bolaños, JP; Fernández, E; Moncada, S; Peiró, C; Romacho, T; Sánchez-Ferrer, CF; Villalobos, L, 2016) |
"Hyperglycemia is proposed to be an independent risk factor for cardiovascular morbidity and mortality." | ( Chen, L; Chen, M; Du, J; Gu, E; Wan, L; Zhang, L, 2016) |
"Perioperative hyperglycemia is a common clinical metabolic disorder." | ( Jiang, H; Wang, J; Zhao, Y; Zhu, M; Zhu, Y, 2016) |
"Diabetic hyperglycemia is a pathophysiological mechanism that triggers multiple maladaptive phenomena." | ( Cividini, F; Dai, A; Diaz-Juarez, J; Diemer, T; Dillmann, WH; Scott, BT; Suarez, J, 2016) |
"Stress hyperglycemia is commonly observed in patients suffering from ischemic heart disease." | ( Fan, C; Li, Z; Wang, H; Xu, Y; Xue, X; Yang, Y; Yu, L; Zhang, J; Zhao, G, 2017) |
"The management of hyperglycemia is challenging in older patients with type 2 diabetes owing to excess fragility and risk for adverse outcomes should hypoglycemia episodes occur." | ( Cook, W; Hirshberg, B; Ohman, P; Perl, S; Wei, C, 2016) |
"Hyperglycemia is associated with worsened clinical outcomes after central nervous system injury." | ( Chuter, T; Fernandez, C; Gasper, W; Hiramoto, JS; Reilly, L; Vartanian, S, 2017) |
"Although hyperglycemia is causally related to adverse outcomes after myocardial ischemia/reperfusion (I/R), the underlying mechanisms are largely unknown." | ( Chen, Y; Li, M; Liu, B; Wang, J; Xu, F; Xue, M; Yuan, Q, 2017) |
"Postprandial hyperglycemia is associated with impaired vascular responsiveness." | ( Murias, JM; Reimer, RA; Soares, RN, 2017) |
"The resulting hyperglycemia is very difficult to treat, and patients are at risk for early morbidity and mortality from complications of diabetes." | ( Cavino, K; Cheng, X; Gromada, J; Kim, SY; Krumm, E; Murphy, AJ; Na, E; Okamoto, H; Yancopoulos, GD, 2017) |
"Hyperglycemia is an important factor for chemoresistance of breast cancer patients with diabetes." | ( Chen, T; Ji, S; Li, X; Liu, Y; Luo, Y; Zeng, D; Zhao, J, 2017) |
"Early hyperglycemia is prevalent in preterm infants receiving parenteral nutrition (PN) therapy." | ( Capone, K; Newton, E; Patton, T; Sentongo, T; Sriram, S; Weinstein, D; Wroblewski, K, 2018) |
"Hyperglycemia is the major risk factor for microvascular complications in patients with type 2 diabetes (T2D)." | ( Abdul-Ghani, M; Chilton, R; DeFronzo, RA; Del Prato, S; Ryder, REJ; Singh, R, 2017) |
"Maternal hyperglycemia is a risk factor for fetal cardiac anomalies." | ( Balistreri, M; Campbell, KF; Da Rocha, AM; Davis, JA; Herron, TJ; Treadwell, MC, 2017) |
"Hyperglycemia is known to exacerbate neuronal death resulted from cerebral ischemia." | ( Hei, C; Li, PA; Liu, P; Niu, J; Yang, X, 2017) |
"Hyperglycemia is a risk factor for cardiovascular mortality and morbidity, and directly responsible for exacerbating macrophage activation and atherosclerosis." | ( Mohanta, J; Pal, A; Rizwan, H; Si, S, 2017) |
"Hyperglycemia is the major risk factor for microvascular complications in type 2 diabetes mellitus (T2DM) patients." | ( Karadag, A; Konukoglu, D; Orhanoglu, T; Senyigit, A; Tabak, O; Ugurlu, S; Uzun, H, 2017) |
"Hyperglycemia is a highly dangerous factor to various diseases, even resulting in death of people." | ( Chen, WK; Ma, D; Miao, CH; Shi, QQ; Sun, PF; Wang, HH; Weng, ML; Zhong, J, 2018) |
"We conclude that hyperglycemia is common during first-line NHL treatment with R-CHOP or DA-EPOCH-R, even in the absence of known diabetes and is associated with alterations of chemotherapy." | ( Dothard, A; Hurd, D; Isom, S; Kennedy, L; Lamar, ZS; Lesser, G; McClain, D; Robinson, M; Vaidya, R, 2018) |
"Early hyperglycemia is associated with multiple organ failure (MOF) after traumatic injury; however, few studies have considered the contribution of depth of clinical shock." | ( Galvagno, SM; Mazzeffi, MA; Richards, JE; Rock, P; Scalea, TM, 2018) |
"Hyperglycemia is one of the severe adverse drug reactions (ADRs) in cancer treatment." | ( He, J; Jia, B; Yan, J; Yang, J, 2017) |
"Furthermore, hyperglycemia is one of the severe ADRs from antineoplastics, which must be paid special attention to when treating in pancreatic carcinoma, especially doxorubicin, fluorouracil, and gemcitabine." | ( He, J; Jia, B; Yan, J; Yang, J, 2017) |
"Hyperglycemia is a common adverse event associated with parenteral nutrition (PN); however, there is no consensus on optimal glucose monitoring." | ( DeChicco, R; Lopez, R; Nishnick, A; Ratliff, A, 2018) |
"Neonatal hyperglycemia is common in extremely low birth weight (ELBW) infants because of physiologic stress, exogenous glucose infusion, and postnatal corticosteroid therapy for hypotension, adrenal insufficiency, and pulmonary immaturity." | ( Flanigan, E; Hwang, MJ; Newman, R; Philla, K, 2018) |
"Steroid-induced hyperglycemia is a commonly neglected symptom in cancer treatment, contributing to poor patient prognosis and extended hospital stay." | ( de Koeijer, E; Sinaga, G, 2018) |
"Early hyperglycemia is associated with higher mortality in trauma and predicts multiple organ failure." | ( Diebel, LN; Diebel, ME; Liberati, DM; Martin, JV, 2018) |
"Stress hyperglycemia is frequently diagnosed in septic patients in critical care units (ICU) and it is associated with greater illness severity and higher morbimortality rates." | ( Aleman, L; Guerrero, J, 2018) |
"Hyperglycemia is an important risk factor for the most severe cardiovascular diseases in patients with diabetes." | ( Chen, Y; Meng, K; Pu, Y; Wang, C; Wang, L; Zhang, X, 2018) |
"Acute hyperglycemia is regarded as a risk factor for critically ill patients; however, insufficient understanding of its nature and underlying mechanisms hinders widespread adoption of glycemic control in critical care units." | ( Gao, F; Han, J; Hu, D; Jia, Y; Li, J; Qin, X; Xie, W; Xu, J; Yang, H; Zhang, X; Zhu, H; Zhu, L, 2019) |
"Chronic hyperglycemia is linked to development of several ocular pathologies affecting the anterior segment, including diabetic corneal neuropathy and keratopathy, neovascular glaucoma, edema, and cataracts leading to significant visual defects." | ( Abbott, RD; Cairns, DM; Deardorff, PM; Funderburgh, JL; Ghezzi, CE; Kaplan, DL; Kenyon, KR; McKay, TB; Wang, S, 2018) |
"Controlling hyperglycemia is therefore crucial in preserving male reproductive function." | ( Ahmad, A; Bakar, ABA; Mohamed, M; Nna, VU, 2019) |
"Hyperglycemia is a metabolic derangement that frequently develops after cardiovascular surgery." | ( Beller, JP; Phadke, D; Tribble, C, 2018) |
"Hyperglycemia is a frequent complication in patients receiving parenteral nutrition (PN) and has been associated with an increased risk of mortality." | ( Hung, N; Kamalay, S; Meyer, JG; Momenzadeh, A; Nguyen, N; Park, A; Truong, S, 2019) |
"Hyperglycemia is a representative hallmark and risk factor for diabetes and is closely linked to diabetes associated complications." | ( Ahmad Hajam, Y; Basheer, M; Ghosh, H; Rai, S; Singh, S, 2018) |
"Hyperglycemia is a common endocrine system disease, which seriously affects people's health with a increasing morbidity in recent years." | ( He, K; Li, X; Ma, H; Ye, X; Zhu, J, 2019) |
"Diet-induced hyperglycemia is described as one major contributor to the formation of advanced glycation end products (AGEs) under inflammatory conditions, crucial in type 2 diabetes progression." | ( Deubel, S; Grune, T; Höhn, A; Kehm, R; Rückriemen, J; Weber, D, 2019) |
"Hyperglycemia is common and associated with increased mortality after out-of-hospital cardiac arrest (OHCA) and return of spontaneous circulation (ROSC)." | ( Ångerman, S; Kuisma, M; Nurmi, J; Pietiläinen, K; Salo, A; Vihonen, H, 2019) |
"Hyperglycemia is common immediately after OHCA and cardiopulmonary resuscitation." | ( Ångerman, S; Kuisma, M; Nurmi, J; Pietiläinen, K; Salo, A; Vihonen, H, 2019) |
"Hyperglycemia is a chief factor in diabetes, a complex disease associated with reproductive disorders, mainly testicular dysfunction, which contributes to male infertility." | ( de Oliveira, AA; Karpova, T; Naas, H; Nunes, KP, 2019) |
"Hyperglycemia is also associated with modifications to epigenetic profiles, indicating an additional role that the high levels of glucose play in freeze tolerance." | ( Hawkins, LJ; Storey, KB; Zhang, J, 2020) |
"Arterial hyperglycemia is associated with poor outcome in traumatic brain injury (TBI), but the pathophysiology is not completely understood." | ( Enblad, P; Hillered, L; Howells, T; Lewén, A; Ronne-Engström, E; Rostami, E; Svedung Wettervik, T, 2019) |
"Hyperglycemia is associated with protein kinase A (PKA)-mediated stimulation of L-type Ca2+ channels in arterial myocytes resulting in increased vasoconstriction." | ( Chiamvimonvat, N; Ghosh, D; Grandi, E; Hell, JW; Morotti, S; Navedo, MF; Nieves-Cintrón, M; Nystoriak, MA; Prada, MP; Reddy, GR; Santana, LF; Sirish, P; Syed, AU; Xiang, YK, 2019) |
"Hyperglycemia is a metabolic dysfunction highly associated with oxidative stress, a classical feature linked to many disorders such as diabetes mellitus." | ( Bobermin, LD; da Rosa, PM; Leite, MC; Meira, LAM; Quincozes-Santos, A; Souza, DO, 2019) |
"Hyperglycemia is a predictor for poor stroke outcome." | ( Castrén, M; Larsson, M; Lindström, V; Nathanson, D; Patrone, C; von Euler, M; Wahlgren, N, 2019) |
"Hyperglycemia is linked to impaired arterial endothelial function (EF), an early sign of cardiovascular disease." | ( de Groot, E; Schweitzer, L; Theis, S, 2020) |
"Hyperglycemia is one of the ischemic neuronal damage triggers that exacerbate the response to oxidative stress, inflammation, and apoptosis induced by cerebral ischemia/reperfusion (I/R) injury." | ( Abdel-Latif, RG; Amin, EF; Rifaai, RA, 2020) |
"Preoperative hyperglycemia is not a risk factor for postoperative complications in a carbohydrate-loaded population when known diabetic patients are excluded." | ( Alimena, S; Contrino Slattery, L; Elias, K; Falzone, M; Feltmate, CM; Prescott, K, 2020) |
"Intraoperative hyperglycemia is associated with infectious complications in general surgery patients." | ( Ahrendt, SA; Bartsch, C; Del Chiaro, M; Friedman, C; Gleisner, A; Halpern, AL; Herter, W; McCarter, MD; Oase, K; Schulick, RD; Sharma, P; Stewart, C; Torphy, RJ, 2020) |
"Intraoperative hyperglycemia is common when dextrose-containing carrier solution is used during HIPEC, and severe intraoperative hyperglycemia is strongly associated with an increased risk for infectious of complications following HIPEC." | ( Ahrendt, SA; Bartsch, C; Del Chiaro, M; Friedman, C; Gleisner, A; Halpern, AL; Herter, W; McCarter, MD; Oase, K; Schulick, RD; Sharma, P; Stewart, C; Torphy, RJ, 2020) |
"Stress-induced hyperglycemia is frequently experienced by critically ill patients and the use of glycemic control (GC) has been shown to improve patient outcomes." | ( Chase, JG; Knopp, JL; Ormsbee, JJ, 2021) |
"Moreover, hyperglycemia is known to induce NKCC1 expression via the activation of the serum-glucocorticoid kinase 1 (SGK1)-NKCC1 pathway." | ( Huang, KL; Lan, CC; Peng, CK; Wu, CP, 2020) |
"Hyperglycemia is common and associated with poor outcome in acute ischemic stroke patients." | ( Deng, J; Xu, X; Zhang, X; Zhang, Y; Zhao, F; Zhao, Y; Zhou, Y, 2020) |
"Hyperglycemia is a feature of worse brain injury after acute ischemic stroke, but the underlying metabolic changes and the link to cytotoxic brain injury are not fully understood." | ( Acharjee, A; Ament, Z; Bevers, MB; Kimberly, WT; Wolcott, Z, 2021) |
"Hyperglycemia is a common comorbidity for ischemic stroke and is associated with worsened neurological outcomes." | ( Campbell, RA; Denorme, F; Kosaka, Y; Portier, I, 2021) |
"Hyperglycemia is the dominant phenotype of diabetes and the main contributor of diabetic complications." | ( DU, GH; He, P; Hou, BY; Ma, P; Qiang, GF; Xu, CY; Yang, XY; Zhang, L; Zhao, YR, 2020) |
"Hyperglycemia is the main cause of the cellular damage seen in DKD." | ( Stanton, RC, 2021) |
"Stress hyperglycemia is a transient increase in blood glucose during acute physiological stress in the absence of glucose homeostasis dysfunction." | ( Bendjelid, K; Giraud, R; Scheen, M, 2021) |
"Hyperglycemia is associated with mortality after trauma; however, few studies have simultaneously investigated the association of depth of shock and acute hyperglycemia." | ( Galvagno, SM; Massey, MS; Mazzeffi, MA; Richards, JE; Rock, P; Scalea, TM, 2021) |
"Perioperative hyperglycemia is common and is associated with significant morbidity." | ( Brown, RE; Desjardins, EM; Smith, BK; Steinberg, GR, 2021) |
"Hyperglycemia is one of the major health concern in many parts of the world." | ( Breen, S; Davis, BA; Garrett, SH; Guyer, R; Kalonick, M; Sens, DA; Shrestha, S; Singhal, S; Somji, S, 2021) |
"However, acute hyperglycemia is suggested to block this protective effect." | ( Feige, K; Heinen, A; Hollmann, MW; Huhn, R; Raupach, A; Ruske, R; Stroethoff, M; Torregroza, C; Yueksel, B, 2021) |
"Postprandial hyperglycemia is a risk factor for type 2 diabetes." | ( Abete, I; Galarregui, C; González-Navarro, CJ; Martínez, JA; Navas-Carretero, S; Zulet, MA, 2021) |
"Similarly, hyperglycemia is known to impair endothelial function and is a predictor of severe cardiovascular outcomes, independent of the presence of diabetes." | ( Boccalone, E; de Donato, A; Frullone, S; Gambardella, J; Martinelli, G; Matarese, A; Mone, P; Pansini, A; Santulli, G, 2021) |
"Admission hyperglycemia is common in subjects with acute myocardial infarction (AMI)." | ( Mauro, C; Minicucci, F; Mone, P; Pansini, A; Rizzo, M, 2022) |
"Hyperglycemia is generally considered to be an important cause of diabetic retinopathy (DR)." | ( Hou, Y; Lin, L; Liu, J; Yu, N; Zhang, Y, 2021) |
"Postprandial hyperglycemia is an important causative factor of type 2 diabetes mellitus, and permanent localization of intestinal GLUT2 in the brush border membrane is an important reason of postprandial hyperglycemia." | ( Dong, L; Li, J; Yang, E; Yang, H; Zhang, M, 2021) |
"Hyperglycemia is often observed in the patients after acute stroke." | ( Bai, SJ; Li, Q; Li, R; Li, XH; Manaenko, A; Shen, YQ; Wu, QY; Xie, P; Xiong, X; Xu, SH; Yang, WS; Yang, X; Zhao, LB, 2022) |
"Chronic hyperglycemia is associated with low response to aerobic exercise training in rodent models and humans, including reduced aerobic exercise capacity and impaired oxidative remodeling in skeletal muscle." | ( Cooney, EM; Hafida, S; Lessard, SJ; MacDonald, TL; Mitri, J; Nava, RC; Pattamaprapanont, P, 2022) |
"Hyperglycemia is one of the most common on-target adverse effects (AEs) of PI3K/AKT inhibitors." | ( Casas, A; Drilon, A; Flory, JH; Garcia, C; Goncalves, MD; Harding, JJ; Harnicar, S; Jhaveri, K; Liu, D; Sisk, AE; Weintraub, MA, 2022) |
"Hyperglycemia is one of the major on-target side effects of PI3K and AKT inhibitors." | ( Casas, A; Drilon, A; Flory, JH; Garcia, C; Goncalves, MD; Harding, JJ; Harnicar, S; Jhaveri, K; Liu, D; Sisk, AE; Weintraub, MA, 2022) |
"Hyperglycemia is considered one of the main risk factors for atherosclerosis, since high glucose levels trigger multiple pathological processes, such as oxidative stress and hyperproduction of pro-inflammatory mediators, leading to endothelial dysfunction." | ( Aleksova, A; Beltrami, AP; Fluca, AL; Gagno, G; Janjusevic, M; Padoan, L; Pierri, A; Sinagra, G; Sorrentino, A, 2022) |
"Perioperative hyperglycemia is a common metabolic disorder in the clinic." | ( Ding, J; Hou, W; Jiang, H; Lu, L; Shao, J; Sun, Z; Wang, F; Zhao, Y, 2022) |
"Hyperglycemia is a condition where an excessive amount of glucose circulates in the bloodstream." | ( Ageel, M; Al-Ghorbani, M; Martiz, RM; Parameswaran, S; Patil, SM; Ramu, R; Ranganatha, L; Satish, AM; Shbeer, AM, 2022) |
"Hyperglycemia is an independent predictor of overall survival and is associated with preexisting DM or lymphatic metastasis in patients with pNENs." | ( Chen, J; Huang, D; Liang, Y; Luo, G; Ni, Q; Wang, L; Xiao, Z; Xu, H; Yu, X; Zhang, P; Zhu, X, 2022) |
"Hyperglycemia is reported to be associated with oxidative stress." | ( Almási, A; Mohammed, HO; Molnár, S; Perjési, P, 2022) |
"Hyperglycemia is highly prevalent in patients with acute ischemic stroke and is associated with increased risk of symptomatic intracranial hemorrhage, larger infarct size and unfavorable outcome." | ( Berkhemer, OA; Borst, J; den Hertog, HM; Dippel, DWJ; Haalboom, M; Kersten, CJBA; Majoie, CB; Roos, YBWEM; van der Lugt, A; van Oostenbrugge, RJ; van Zwam, WH; Zandbergen, AAM, 2022) |
"Furthermore, hyperglycemia is a risk factor for poor disease prognosis." | ( Kitazawa, T; Nakayama, S; Wakabayashi, Y; Yamamoto, A, 2022) |
"It suggests that hyperglycemia is a factor that may contribute to a more malignant phenotype of cancer cells by inhibition of oxidative phosphorylation and apoptosis." | ( Abramczyk, H; Beton, K; Jarczewska, K; Kopeć, M, 2022) |
"Hyperglycemia is mainly caused by insufficient insulin secretion or insulin resistance." | ( Cao, F; Li, D; Li, W; Tan, X; Wen, L; Wu, D; Xing, J; Zhong, M, 2022) |
"Hyperglycemia is a state in which excess glucose circulates in blood." | ( Arif, A; Mahmood, R; Qasim, N, 2023) |
"Hyperglycemia is a state in which excess glucose circulates in blood." | ( Arif, A; Mahmood, R; Qasim, N, 2023) |
"Hyperglycemia is a state in which excess glucose circulates in blood." | ( Arif, A; Mahmood, R; Qasim, N, 2023) |
"Perioperative hyperglycemia is associated with adverse outcomes for patients with and without diabetes." | ( Baghirzada, L; Cameron, A; Chong, M; Harrison, TG; Krahn, D; Morin, N; Ruzycki, SM; Taylor, S, 2023) |
"Perioperative hyperglycemia is associated with adverse outcomes for patients with and without diabetes." | ( Baghirzada, L; Cameron, A; Chong, M; Harrison, TG; Krahn, D; Morin, N; Ruzycki, SM; Taylor, S, 2023) |
"Exercise-induced hyperglycemia is recognized in type 1 diabetes (T1D) clinical guidelines, but its association with high-intensity intermittent exercise (HIIE) in acute studies is inconsistent." | ( Alcántara-Cordero, FJ; Boulé, NG; Hart, S; Maldaner, M; McClure, RD; Nitz, C; Weseen, E; Yardley, JE, 2023) |
"Hyperglycemia is a typical characteristic of diabetes." | ( Contreras, CM; Gutiérrez García, AG, 2023) |
"Whether admission hyperglycemia is differentially associated with early vascular outcomes in acute ischemic stroke (AIS) depending on stroke subtype has been incompletely delineated." | ( Bae, HJ; Cha, JK; Cho, YJ; Choi, JC; Choi, KH; Hong, JH; Hong, KS; Kang, J; Kang, K; Kim, BJ; Kim, DE; Kim, DH; Kim, JG; Kim, JT; Kim, WJ; Kwon, JH; Lee, BC; Lee, J; Lee, JS; Lee, KB; Lee, KJ; Lee, SH; Lee, SJ; Oh, MS; Park, HK; Park, JM; Park, MS; Park, TH; Ryu, WS; Saver, JL; Shin, DI; Sohn, SI; Yu, KH; Yum, KS, 2023) |
"Hyperglycemia is one of the poor prognostic factors in critical ill sepsis patients with diabetes." | ( He, W; Lai, D; Lin, S, 2022) |
"Hyperglycemia is a risk factor for breast cancer-related morbidity and mortality." | ( Jo, W; Kim, CS; Kim, M; Kim, S; Lee, C; Lee, KH; Oh, J; Park, C; Park, J; Ryu, HS; Seo, JK, 2023) |
"Hyperglycemia is common in acute ischemic stroke and is associated with larger infarct volume and unfavorable functional outcome, also in patients who undergo reperfusion therapy." | ( den Hertog, HM; Fokkert, MJ; Kersten, CJBA; Slingerland, RJ; Zandbergen, AAM, 2023) |
"Hyperglycemia is recognized as a common adverse event for patients receiving alpelisib but has been little studied outside of clinical trials." | ( Behrendt, CE; Ge, X; Lavasani, S; Mortimer, J; Patel, N; Samoa, R; Sedrak, M; Stewart, D; Waisman, J; Yost, SE; Yuan, Y, 2023) |
"Though hyperglycemia is associated with poor outcomes, no guidelines for identifying drug-induced hyperglycemia currently exist, and the time course for developing hyperglycemia remains relatively uncharacterized after induction therapy." | ( Diaz, M; Hamby, T; Hill, R; Levitt, M; Mohamed, A; Siebert, G, 2023) |
"Hyperglycemia is a major adverse event of phosphatidylinositol 3-kinase/AKT inhibitor class of cancer therapeutics." | ( Harun, R; Jin, JY; Lu, J; Sane, R; Sutaria, DS; Yoshida, K, 2023) |
"Hyperglycemia is commonly encountered in extremely preterm newborns and physiologically can be attributed to immaturity in several biochemical pathways related to glucose metabolism." | ( Angelis, D; Brion, LP; Jaleel, MA, 2023) |
"Preoperative hyperglycemia is an important predictor of postoperative complications and recurrence after CAWR." | ( Brown, C; Faulkner, HR; Losken, A; Marxen, T; Su, S, 2023) |
"Hyperglycemia is a long-lasting syndrome that occurs either when the pancreas cannot produce enough insulin, or the body cannot effectively utilize that insulin to regulate blood sugar levels." | ( Ahmed, A; Akram, A; Ali Khan, R; Azeem, I; Azizuddin, -; Furrukh, M; Naseem Khan, M; Tabassum, N, 2023) |
"Stress induced hyperglycemia is the body's protect response against strong (patho-physiological and/or psychological) stress, sometimes the blood glucose level is too high due to out of the body's adjustment." | ( An, Y, 2023) |