dacarbazine

A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.

ChEBI ID: 4305

Members (1)

Member	Definition	Role
dacarbazine	A dacarbazine in which the N=N double bond adopts a trans-configuration.	(E)-dacarbazine

Research

Studies (7,204)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	916 (12.72)	18.7374
1990's	757 (10.51)	18.2507
2000's	1,775 (24.64)	29.6817
2010's	3,385 (46.99)	24.3611
2020's	371 (5.15)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	1,463 (19.36%)	5.53%
Reviews	787 (10.42%)	6.00%
Case Studies	1,122 (14.85%)	4.05%
Observational	17 (0.22%)	0.25%
Other	4,167 (55.15%)	84.16%